BR9910927A - Composto, composições farmacêuticas, processo para tratamento de depressão, ansiedade, psicoses, doença de parkinson, obesidade, hipertensão, sìndrome de tourette, disfunção sexual, toxicomania, abuso de droga, distúrbios cognitivos, doença de alzheimer, demência senil, comportamento obsessivo-compulsivo, ataques de pânico, indisposições alimentares, anorexia, distúrbios cardiovascular e cerebrovascular, enxaqueca, diabetes melitus não dependente de insulina, hiperglicemia, constipação, arritmia, distúrbios do sistema neuroendócrino, tensão, hipertrofia prostática, sintomas extrapiramidais induzidos por drogas ou espasticidade, uso de um composto, e, processo para preparação do composto - Google Patents
Composto, composições farmacêuticas, processo para tratamento de depressão, ansiedade, psicoses, doença de parkinson, obesidade, hipertensão, sìndrome de tourette, disfunção sexual, toxicomania, abuso de droga, distúrbios cognitivos, doença de alzheimer, demência senil, comportamento obsessivo-compulsivo, ataques de pânico, indisposições alimentares, anorexia, distúrbios cardiovascular e cerebrovascular, enxaqueca, diabetes melitus não dependente de insulina, hiperglicemia, constipação, arritmia, distúrbios do sistema neuroendócrino, tensão, hipertrofia prostática, sintomas extrapiramidais induzidos por drogas ou espasticidade, uso de um composto, e, processo para preparação do compostoInfo
- Publication number
- BR9910927A BR9910927A BR9910927-1A BR9910927A BR9910927A BR 9910927 A BR9910927 A BR 9910927A BR 9910927 A BR9910927 A BR 9910927A BR 9910927 A BR9910927 A BR 9910927A
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- disorders
- disease
- spasticity
- psychosis
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 7
- 208000024827 Alzheimer disease Diseases 0.000 title abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 4
- 208000035475 disorder Diseases 0.000 title abstract 4
- 229940079593 drug Drugs 0.000 title abstract 4
- 239000003814 drug Substances 0.000 title abstract 4
- 208000019901 Anxiety disease Diseases 0.000 title abstract 3
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 title abstract 3
- 206010010774 Constipation Diseases 0.000 title abstract 3
- 208000027776 Extrapyramidal disease Diseases 0.000 title abstract 3
- 206010020772 Hypertension Diseases 0.000 title abstract 3
- 208000019695 Migraine disease Diseases 0.000 title abstract 3
- 208000008238 Muscle Spasticity Diseases 0.000 title abstract 3
- 208000008589 Obesity Diseases 0.000 title abstract 3
- 206010033664 Panic attack Diseases 0.000 title abstract 3
- 208000018737 Parkinson disease Diseases 0.000 title abstract 3
- 208000004403 Prostatic Hyperplasia Diseases 0.000 title abstract 3
- 208000028017 Psychotic disease Diseases 0.000 title abstract 3
- 201000001880 Sexual dysfunction Diseases 0.000 title abstract 3
- 208000000323 Tourette Syndrome Diseases 0.000 title abstract 3
- 208000016620 Tourette disease Diseases 0.000 title abstract 3
- 208000022531 anorexia Diseases 0.000 title abstract 3
- 230000036506 anxiety Effects 0.000 title abstract 3
- 206010003119 arrhythmia Diseases 0.000 title abstract 3
- 230000006793 arrhythmia Effects 0.000 title abstract 3
- 206010061428 decreased appetite Diseases 0.000 title abstract 3
- 230000002526 effect on cardiovascular system Effects 0.000 title abstract 3
- 201000001421 hyperglycemia Diseases 0.000 title abstract 3
- 206010027599 migraine Diseases 0.000 title abstract 3
- 235000020824 obesity Nutrition 0.000 title abstract 3
- 208000019906 panic disease Diseases 0.000 title abstract 3
- 201000004240 prostatic hypertrophy Diseases 0.000 title abstract 3
- 231100000872 sexual dysfunction Toxicity 0.000 title abstract 3
- 208000018198 spasticity Diseases 0.000 title abstract 3
- 208000011117 substance-related disease Diseases 0.000 title abstract 3
- 208000001072 type 2 diabetes mellitus Diseases 0.000 title abstract 3
- 208000024172 Cardiovascular disease Diseases 0.000 title abstract 2
- 206010013654 Drug abuse Diseases 0.000 title abstract 2
- 206010039966 Senile dementia Diseases 0.000 title abstract 2
- 208000026106 cerebrovascular disease Diseases 0.000 title abstract 2
- 208000010877 cognitive disease Diseases 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 210000000607 neurosecretory system Anatomy 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 206010013663 drug dependence Diseases 0.000 title 1
- 208000020401 Depressive disease Diseases 0.000 abstract 2
- 208000030814 Eating disease Diseases 0.000 abstract 1
- 208000019454 Feeding and Eating disease Diseases 0.000 abstract 1
- 201000004311 Gilles de la Tourette syndrome Diseases 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 235000014632 disordered eating Nutrition 0.000 abstract 1
- 230000000955 neuroendocrine Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Addiction (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
"COMPOSTO, COMPOSIçõES FARMACêUTICAS, PROCESSO PARA TRATAMENTO DE DEPRESSãO, ANSIEDADE, PSICOSES, DOENçA DE PARKINSON, OBESIDADE, HIPERTENSãO, SìNDROME DE TOURETTE, DISFUNçãO SEXUAL, TOXICOMANIA, ABUSO DE DROGA, DISTúRBIOS COGNITIVOS, DOENçA DE ALZHEIMER, DEMêNCIA SENIL, COMPORTAMENTO OBSESSIVO-COMPULSIVO, ATAQUES DE PâNICO, INDISPOSIçõES ALIMENTARES, ANOREXIA, DISTúRBIOS CARDIOVASCULAR E CEREBROVASCULAR, ENXAQUECA, DIABETES MELITUS NãO DEPENDENTE DE INSULINA, HIPERGLICEMIA, CONSTIPAçãO, ARRITMIA, DISTúRBIOS DO SISTEMA NEUROENDóCRINO, TENSãO, HIPERTROFIA PROSTáTICA, SINTOMAS EXTRAPIRAMIDAIS INDUZIDOS POR DROGA OU ESPASTICIDADE, USO DE UM COMPOSTO, E, PROCESSO PARA PREPARAçãO DO COMPOSTO" Compostos de fórmula (I): incluindo seus sais farmaceuticamente aceitáveis em que o R representa H ou F, sua preparação e seu uso no tratamento de depressão, ansiedade, psicoses, doença de Parkinson, obesidade, hipertensão, síndrome de Tourette, disfunção sexual, toxicomania, abuso de droga, distúrbios cognitivos, doença de Alzheimer, demência senil, comportamento obsessivo-compulsivo, ataques de pânico, indisposições alimentares, anorexia, distúrbios cardiovascular e cerebrovascular, enxaqueca, diabetes melitus não dependente de insulina, hiperglicemia, constipação, arritmia, distúrbios do sistema neuroendócrino, tensão, hipertrofia prostática, sintomas extrapiramidais induzidos por droga ou espasticidade são descritos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9811879.7A GB9811879D0 (en) | 1998-06-03 | 1998-06-03 | Therapeutic agents |
| PCT/EP1999/003648 WO1999062902A1 (en) | 1998-06-03 | 1999-05-26 | N-benzodioxanylmethyl-1-piperidyl-methylamine compounds having affinity for 5-ht receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9910927A true BR9910927A (pt) | 2001-02-20 |
Family
ID=10833098
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9910927-1A BR9910927A (pt) | 1998-06-03 | 1999-05-26 | Composto, composições farmacêuticas, processo para tratamento de depressão, ansiedade, psicoses, doença de parkinson, obesidade, hipertensão, sìndrome de tourette, disfunção sexual, toxicomania, abuso de droga, distúrbios cognitivos, doença de alzheimer, demência senil, comportamento obsessivo-compulsivo, ataques de pânico, indisposições alimentares, anorexia, distúrbios cardiovascular e cerebrovascular, enxaqueca, diabetes melitus não dependente de insulina, hiperglicemia, constipação, arritmia, distúrbios do sistema neuroendócrino, tensão, hipertrofia prostática, sintomas extrapiramidais induzidos por drogas ou espasticidade, uso de um composto, e, processo para preparação do composto |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP1087964A1 (pt) |
| JP (1) | JP2002517392A (pt) |
| KR (1) | KR20010052526A (pt) |
| CN (1) | CN1304408A (pt) |
| AR (1) | AR018622A1 (pt) |
| AU (1) | AU4369599A (pt) |
| BG (1) | BG104988A (pt) |
| BR (1) | BR9910927A (pt) |
| CA (1) | CA2333756A1 (pt) |
| CO (1) | CO5021190A1 (pt) |
| GB (1) | GB9811879D0 (pt) |
| HR (1) | HRP20010005A2 (pt) |
| HU (1) | HUP0102233A2 (pt) |
| ID (1) | ID27067A (pt) |
| IL (1) | IL139552A0 (pt) |
| NO (1) | NO20006041D0 (pt) |
| PL (1) | PL344594A1 (pt) |
| SK (1) | SK17602000A3 (pt) |
| TR (1) | TR200003569T2 (pt) |
| WO (1) | WO1999062902A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9915616D0 (en) * | 1999-07-05 | 1999-09-01 | Knoll Ag | Therapeutic agents |
| GB0007376D0 (en) * | 2000-03-28 | 2000-05-17 | Knoll Ag | Therapeutic agents |
| US20030186838A1 (en) * | 2000-05-12 | 2003-10-02 | Feenstra Roelof W. | Use of compounds having combined dopamine d2, 5-ht1a and alpha adrenoreceptor agonistic action for treating cns disorders |
| CZ301464B6 (cs) * | 2000-05-12 | 2010-03-10 | Solvay Pharmaceuticals B. V. | Piperazinové a piperidinové slouceniny, zpusob jejich prípravy a farmaceutické prostredky, které je obsahují |
| BRPI0510642A (pt) * | 2004-05-05 | 2007-11-20 | Hoffmann La Roche | arilsulfonil benzodioxanos úteis para modulação do receptor de 5-ht6, do receptor de 5ht2a ou ambos |
| JP2008530229A (ja) | 2005-02-17 | 2008-08-07 | ワイス | シクロアルキル縮合インドール、ベンゾチオフェン、ベンゾフランおよびインデン誘導体 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2681325B1 (fr) * | 1991-09-16 | 1993-12-17 | Fabre Medicament Pierre | Derives de l'aminomethyl-4 piperidine, leur preparation et leur application en therapeutique. |
| FR2701479B1 (fr) * | 1993-02-11 | 1995-05-12 | Pf Medicament | Nouveaux dérivés hétérocycliques de l'aminométhyl-4 pipéridine, leur préparation et leur application en thérapeutique. |
| GB9318431D0 (en) * | 1993-09-06 | 1993-10-20 | Boots Co Plc | Therapeutic agents |
| GB9514380D0 (en) * | 1995-07-13 | 1995-09-13 | Knoll Ag | Therapeutic agents |
-
1998
- 1998-06-03 GB GBGB9811879.7A patent/GB9811879D0/en not_active Ceased
-
1999
- 1999-05-26 SK SK1760-2000A patent/SK17602000A3/sk unknown
- 1999-05-26 ID IDW20002519A patent/ID27067A/id unknown
- 1999-05-26 IL IL13955299A patent/IL139552A0/xx unknown
- 1999-05-26 EP EP99926434A patent/EP1087964A1/en not_active Ceased
- 1999-05-26 KR KR1020007013670A patent/KR20010052526A/ko not_active Withdrawn
- 1999-05-26 JP JP2000552113A patent/JP2002517392A/ja active Pending
- 1999-05-26 AU AU43695/99A patent/AU4369599A/en not_active Abandoned
- 1999-05-26 BR BR9910927-1A patent/BR9910927A/pt not_active IP Right Cessation
- 1999-05-26 CN CN99806908A patent/CN1304408A/zh active Pending
- 1999-05-26 HU HU0102233A patent/HUP0102233A2/hu unknown
- 1999-05-26 CA CA002333756A patent/CA2333756A1/en not_active Abandoned
- 1999-05-26 HR HR20010005A patent/HRP20010005A2/hr not_active Application Discontinuation
- 1999-05-26 TR TR2000/03569T patent/TR200003569T2/xx unknown
- 1999-05-26 WO PCT/EP1999/003648 patent/WO1999062902A1/en not_active Ceased
- 1999-05-26 PL PL99344594A patent/PL344594A1/xx not_active Application Discontinuation
- 1999-06-03 AR ARP990102619A patent/AR018622A1/es not_active Application Discontinuation
- 1999-06-03 CO CO99035020A patent/CO5021190A1/es unknown
-
2000
- 2000-11-27 BG BG104988A patent/BG104988A/bg unknown
- 2000-11-29 NO NO20006041A patent/NO20006041D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20010005A2 (en) | 2001-12-31 |
| IL139552A0 (en) | 2002-02-10 |
| AU4369599A (en) | 1999-12-20 |
| AR018622A1 (es) | 2001-11-28 |
| TR200003569T2 (tr) | 2001-04-20 |
| NO20006041L (no) | 2000-11-29 |
| SK17602000A3 (sk) | 2001-08-06 |
| GB9811879D0 (en) | 1998-07-29 |
| NO20006041D0 (no) | 2000-11-29 |
| CO5021190A1 (es) | 2001-03-27 |
| WO1999062902A1 (en) | 1999-12-09 |
| EP1087964A1 (en) | 2001-04-04 |
| ID27067A (id) | 2001-02-22 |
| BG104988A (bg) | 2001-11-30 |
| JP2002517392A (ja) | 2002-06-18 |
| HUP0102233A2 (hu) | 2002-05-29 |
| KR20010052526A (ko) | 2001-06-25 |
| PL344594A1 (en) | 2001-11-05 |
| CA2333756A1 (en) | 1999-12-09 |
| CN1304408A (zh) | 2001-07-18 |
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