[go: up one dir, main page]

NO976128L - Forbindelser og farmasöytiske blandinger som inneholder dem - Google Patents

Forbindelser og farmasöytiske blandinger som inneholder dem

Info

Publication number
NO976128L
NO976128L NO976128A NO976128A NO976128L NO 976128 L NO976128 L NO 976128L NO 976128 A NO976128 A NO 976128A NO 976128 A NO976128 A NO 976128A NO 976128 L NO976128 L NO 976128L
Authority
NO
Norway
Prior art keywords
compounds
pharmaceutical compositions
compositions containing
pharmaceutical
compositions
Prior art date
Application number
NO976128A
Other languages
English (en)
Other versions
NO976128D0 (no
Inventor
Lan Mong Nguyen
Eric Niesor
Craig Leigh Bentzen
Hieu Trung Phan
Vinh Van Diep
Simon Floret
Raymond Azoulay
Alexandre Bulla
Yves Guyon-Gellin
Robert John Ife
Original Assignee
Symphar Sa
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symphar Sa, Smithkline Beecham Plc filed Critical Symphar Sa
Publication of NO976128D0 publication Critical patent/NO976128D0/no
Publication of NO976128L publication Critical patent/NO976128L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4056Esters of arylalkanephosphonic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/58Pyridine rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/59Hydrogenated pyridine rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO976128A 1995-06-30 1997-12-29 Forbindelser og farmasöytiske blandinger som inneholder dem NO976128L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH01920/95A CH690264A5 (fr) 1995-06-30 1995-06-30 Dérivés aminophosphonates substitués, leur procédé de préparation et leur utilisation pour la préparation de compositions pharmaceutiques.
PCT/EP1996/002842 WO1997002037A1 (en) 1995-06-30 1996-06-26 Compounds and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
NO976128D0 NO976128D0 (no) 1997-12-29
NO976128L true NO976128L (no) 1998-02-10

Family

ID=4221681

Family Applications (1)

Application Number Title Priority Date Filing Date
NO976128A NO976128L (no) 1995-06-30 1997-12-29 Forbindelser og farmasöytiske blandinger som inneholder dem

Country Status (27)

Country Link
US (2) US6060464A (no)
EP (1) EP0835116A1 (no)
JP (1) JPH11508576A (no)
KR (1) KR19990028542A (no)
CN (1) CN1113654C (no)
AP (1) AP778A (no)
AR (1) AR004498A1 (no)
AU (1) AU705206B2 (no)
BG (1) BG102215A (no)
BR (1) BR9609653A (no)
CA (1) CA2225391A1 (no)
CH (1) CH690264A5 (no)
CZ (1) CZ422097A3 (no)
EA (1) EA199800106A1 (no)
HU (1) HUP9901684A3 (no)
IL (1) IL122717A0 (no)
MA (1) MA24340A1 (no)
MX (1) MX9800189A (no)
NO (1) NO976128L (no)
NZ (1) NZ312696A (no)
OA (1) OA10554A (no)
PL (1) PL187024B1 (no)
SK (1) SK178397A3 (no)
TR (1) TR199701700T1 (no)
TW (1) TW413681B (no)
WO (1) WO1997002037A1 (no)
ZA (1) ZA965505B (no)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548084B2 (en) 1995-07-20 2003-04-15 Smithkline Beecham Plc Controlled release compositions
GB9626615D0 (en) * 1996-12-20 1997-02-05 Symphar Sa Novel compounds
GB9626536D0 (en) * 1996-12-20 1997-02-05 Symphar Sa Novel compounds
GB9626616D0 (en) * 1996-12-20 1997-02-05 Symphar Sa Novel compounds
DE19748659A1 (de) * 1997-11-04 1999-05-06 Hoechst Ag Aminophosphoniumgruppen enthaltende vernetzte Copolymere für medizinische Verwendungen
US6017918A (en) * 1998-08-06 2000-01-25 Warner-Lambert Company Phenyl glycine compounds and methods of treating atherosclerosis and restenosis
US6284795B1 (en) 1998-09-04 2001-09-04 Warner-Lambert Company Sulfonamide compounds and methods of treating atherosclerosis and restenosis
AU775885B2 (en) 1999-10-27 2004-08-19 Teva Pharmaceutical Industries Ltd. Use of 1-aminoindan derivatives for treatment of mania in bipolar mood disorder
AU2001235466B2 (en) 2000-02-16 2004-04-22 Glaxo Group Limited Pyrimidine-4-one derivatives as LDL-PLA2 inhibitors
AU2001294792B2 (en) * 2000-09-27 2006-12-14 Ilex Products, Inc. Alpha-substituted beta-aminoethyl phosphonates
US20030114421A1 (en) * 2000-09-27 2003-06-19 Phan Hieu Trung Alpha-substituted beta-aminoethyl phosphonate derivatives
GB0024808D0 (en) 2000-10-10 2000-11-22 Smithkline Beecham Plc Novel compounds
GB0025849D0 (en) * 2000-10-23 2000-12-06 Smithkline Beecham Plc Novel compounds
US20050124581A1 (en) * 2002-02-11 2005-06-09 Phan Hieu T. Alpha-substituted heteroarylalkyl phosphonate derivatives
EP1504013A4 (en) * 2002-05-11 2006-05-03 Ilex Products Inc USE OF HYDROXYPHOSPHONATES AND PHOSPHONOPHOSPHATES AS MODULATORS OF APOLIPOPROTEIN E
EP1534679A4 (en) * 2002-08-30 2007-06-06 Biostratum Inc INHIBITORS OF POST-AMADORI ADVANCED GLYCATION ENDPRODUCTS
CA2820408C (en) 2010-12-06 2018-03-06 Glaxo Group Limited Pyrimidinone compounds for use in the treatment of diseases or conditions mediated by lp-pla2
JP2014521625A (ja) 2011-07-27 2014-08-28 グラクソ グループ リミテッド 二環式ピリミドン化合物
JP2014521611A (ja) 2011-07-27 2014-08-28 グラクソ グループ リミテッド Lp−PLA2阻害剤としての2,3−ジヒドロイミダゾ[1,2−c]ピリミジン−5(1H)−オン化合物の使用
AU2012300841C1 (en) 2011-09-01 2016-02-18 Glaxo Group Limited Novel crystal form
JP2016505053A (ja) 2013-01-25 2016-02-18 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited Lp‐PLA2の阻害剤としての二環式ピリミドン化合物
WO2014114694A1 (en) 2013-01-25 2014-07-31 Glaxosmithkline Intellectual Property Development Limited 2,3-dihydroimidazol[1,2-c]pyrimidin-5(1h)-one based lipoprotein-associated phospholipase a2 (lp-pla2) inhibitors
CA2899124A1 (en) 2013-01-25 2014-07-31 Glaxosmithkline Intellectual Property Development Limited Compounds
WO2016012917A1 (en) 2014-07-22 2016-01-28 Glaxosmithkline Intellectual Property Development Limited 1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidine derivatives useful in the treatment of diseases and disorders mediated by lp-pla2
WO2016012916A1 (en) 2014-07-22 2016-01-28 Glaxosmithkline Intellectual Property Development Limited 1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidine derivatives useful in the treatment of diseases and disorders mediated by lp-pla2
WO2021089032A1 (zh) 2019-11-09 2021-05-14 上海赛默罗生物科技有限公司 三环二氢咪唑并嘧啶酮衍生物、其制备方法、药物组合物和用途
CN115304620A (zh) 2021-05-07 2022-11-08 上海赛默罗生物科技有限公司 嘧啶酮衍生物、其制备方法、药物组合物和用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH683996A5 (fr) * 1992-03-05 1994-06-30 Symphar Sa Dérivés aminophosphonates substitués, leur procédé de préparation et compositions pharmaceutiques les contenant.
DE4433244A1 (de) * 1994-09-19 1996-03-28 Hoechst Ag Aminomethylphosphon- und Aminomethylphosphinsäure-Derivate und deren Verwendung zur Behandlung von degenerativen Gelenkserkrankungen

Also Published As

Publication number Publication date
CH690264A5 (fr) 2000-06-30
EA199800106A1 (ru) 1998-08-27
AP9701160A0 (en) 1998-01-31
TR199701700T1 (xx) 1998-03-21
MA24340A1 (fr) 1998-07-01
PL187024B1 (pl) 2004-04-30
CZ422097A3 (cs) 1998-10-14
HUP9901684A2 (hu) 1999-09-28
CN1113654C (zh) 2003-07-09
PL324341A1 (en) 1998-05-25
NZ312696A (en) 1999-10-28
AU705206B2 (en) 1999-05-20
AU6418596A (en) 1997-02-05
US6060464A (en) 2000-05-09
EP0835116A1 (en) 1998-04-15
AR004498A1 (es) 1998-12-16
TW413681B (en) 2000-12-01
SK178397A3 (en) 1998-06-03
MX9800189A (es) 1998-04-30
CA2225391A1 (en) 1997-01-23
BR9609653A (pt) 1999-12-21
BG102215A (en) 1998-09-30
CN1193913A (zh) 1998-09-23
HUP9901684A3 (en) 2000-04-28
NO976128D0 (no) 1997-12-29
OA10554A (en) 2002-05-29
KR19990028542A (ko) 1999-04-15
IL122717A0 (en) 1998-08-16
JPH11508576A (ja) 1999-07-27
AP778A (en) 1999-10-29
WO1997002037A1 (en) 1997-01-23
US6660724B1 (en) 2003-12-09
ZA965505B (en) 1998-03-30

Similar Documents

Publication Publication Date Title
NO976128L (no) Forbindelser og farmasöytiske blandinger som inneholder dem
NO975985L (no) Aromatiske forbindelser og farmasöytiske blandinger inneholdende dem
NO975984L (no) Aromatiske forbindelser og farmasöytiske blandinger inneholdende dem
CY2005007I2 (el) Φαρμακευτικες συνθεσεις που περιεχουν δαριφενακινη
FI973039A0 (fi) Uusia farnesyylitransferaasin inhibiittoreita, niiden valmistus ja niitä sisältäviä farmaseuttisia koostumuksia
IS4706A (is) Lyfjasamsetningar
FI973279A0 (fi) Uudet farnesyylitransferaasin inhibiittorit, niiden valmistus ja niitä sisältävät farmaseuttiset koostumukset
DK0747050T3 (da) Farmaceutiske sammensætninger indeholdende irbesartan
NO942835D0 (no) 1-benzensulfonyl-1,3-dihydro-2H-benzimidazol-2-on-derivater, fremstilling derav og farmasöytiske blandinger som inneholder dem
NO301824B1 (no) 1-benzensulfonyl-1,3-dihydro-indol-2-on-derivater og farmasöytiske blandinger som inneholder dem
IL138028A0 (en) Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical use
NO20004345D0 (no) Farmasøytisk sammensetning
NO306114B1 (no) Substituerte 4-fenyltiazolderivater og farmasöytiske blandinger som inneholder dem
NO950537L (no) Polysubstituerte 3-acylamino-5-fenyl-1,4-benzodiazepin-2-on-derivater, fremgangsmåter for fremstilling derav og farmasöytiske blandinger inneholdende dem
DK0732328T3 (da) Heterocykliske, aromatiske forbindelser, farmaceutiske og kosmetiske sammensætninger, der indeholder dem, og anvendelser
NO941374L (no) 5-acylamino-1,2,4-tiadiazoler, fremstilling derav og farmasöytiske blandinger inneholdende dem
NO975365L (no) Benzopyraner og farmasöytiske sammensetninger inneholdende dem
LV11727A (lv) Farmaceitiska kompozicija
NO308004B1 (no) Nye aminofenylfosfonsyreforbindelser og farmasøytiske sammensetninger inneholdende dem
FI973280L (fi) Farmaseuttinen koostumus
DK0776328T3 (da) 8-fluoranthracycliner, fremgangsmåder til fremstilling deraf og farmaceutiske præparater indeholdende dem
BR9605777A (pt) Composição farmacêutica
DK0721456T3 (da) Anthracyclindisaccharider, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende dem
BR9605131A (pt) Composição farmacêutica
NO179172C (no) Nytt arylpiperidin-derivat og farmasöytiske blandinger som inneholder det

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application