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NO962539L - 5-(2-imidazolinylamino)benzimidazol-derivater, deres fremstilling og deres anvendelse som -2-adreniceptor-agonister - Google Patents

5-(2-imidazolinylamino)benzimidazol-derivater, deres fremstilling og deres anvendelse som -2-adreniceptor-agonister

Info

Publication number
NO962539L
NO962539L NO962539A NO962539A NO962539L NO 962539 L NO962539 L NO 962539L NO 962539 A NO962539 A NO 962539A NO 962539 A NO962539 A NO 962539A NO 962539 L NO962539 L NO 962539L
Authority
NO
Norway
Prior art keywords
adreniceptor
imidazolinylamino
agonists
preparation
unsubstituted
Prior art date
Application number
NO962539A
Other languages
English (en)
Other versions
NO962539D0 (no
NO309325B1 (no
Inventor
Thomas Lee Cupps
Sophie Eva Bogdan
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26865464&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO962539(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of NO962539D0 publication Critical patent/NO962539D0/no
Publication of NO962539L publication Critical patent/NO962539L/no
Publication of NO309325B1 publication Critical patent/NO309325B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO962539A 1993-12-17 1996-06-14 5-(2-imidazolinylamino)benzimidazol-derivater, anvendelse derav, og farmasöytiske preparater omfattende slike forbindelser NO309325B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16986893A 1993-12-17 1993-12-17
US08/349,558 US5478858A (en) 1993-12-17 1994-12-08 5-(2-imidazolinylamino) benzimidazole compounds useful as alpha-2 adrenoceptor agonists
PCT/US1994/014292 WO1995016685A1 (en) 1993-12-17 1994-12-15 5-(2-imidazolinylamino)benzimidazole derivatives, their preparation and their use as alpha-2 adrenoceptor agonists

Publications (3)

Publication Number Publication Date
NO962539D0 NO962539D0 (no) 1996-06-14
NO962539L true NO962539L (no) 1996-08-13
NO309325B1 NO309325B1 (no) 2001-01-15

Family

ID=26865464

Family Applications (1)

Application Number Title Priority Date Filing Date
NO962539A NO309325B1 (no) 1993-12-17 1996-06-14 5-(2-imidazolinylamino)benzimidazol-derivater, anvendelse derav, og farmasöytiske preparater omfattende slike forbindelser

Country Status (23)

Country Link
US (3) US5478858A (no)
EP (1) EP0736022B1 (no)
JP (1) JPH09507216A (no)
KR (1) KR100385195B1 (no)
CN (1) CN1076352C (no)
AT (1) ATE250598T1 (no)
AU (1) AU699631B2 (no)
BR (1) BR9408343A (no)
CA (1) CA2179008C (no)
CZ (1) CZ286816B6 (no)
DE (1) DE69433181T2 (no)
ES (1) ES2202352T3 (no)
FI (1) FI962494L (no)
HU (1) HU224016B1 (no)
MY (1) MY131696A (no)
NO (1) NO309325B1 (no)
NZ (1) NZ333371A (no)
PL (1) PL180903B1 (no)
RU (1) RU2143430C1 (no)
SG (1) SG49049A1 (no)
SK (1) SK282566B6 (no)
TW (1) TW393469B (no)
WO (1) WO1995016685A1 (no)

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EP0775134A4 (en) 1994-08-04 1997-08-13 Synaptic Pharma Corp NEW BENZIMIDAZOLE DERIVATIVES
KR100405116B1 (ko) * 1995-02-28 2004-02-05 아벤티스 파마슈티칼스 인크. 피페리디노알칸올화합물에대한약제학적조성물
US5677321A (en) 1996-02-29 1997-10-14 Synaptic Pharmaceutical Corporation 5- and 6-(2-imidazolin-2-ylamino) and -(2-thiazolin-2-ylamino)-benzothiazoles as alpha-2 adrenergic ligands
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US6525018B1 (en) 1999-05-17 2003-02-25 The General Hospital Corp. Treating eye disorders using intestinal trefoil proteins
AU730369B2 (en) 1996-11-25 2001-03-08 Board Of Regents Of The University Of Nebraska, The Guanidinyl heterocycle compounds useful as alpha-2 adrenoceptor agonists
US6172095B1 (en) 1996-11-25 2001-01-09 The Procter & Gamble Company Guanidinylamino heterocycle compounds useful as alpha-2 adrenoceptor agonists
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ATE232518T1 (de) * 1996-11-25 2003-02-15 Procter & Gamble Guanidinylamino-heterocyclische verbindungen als alpha-2 adrenoceptor agonisten
US6306877B1 (en) 1999-08-09 2001-10-23 The Procter & Gamble Co. Guanidinylamino heterocycle compounds useful as alpha-2 adrenoceptor agonists
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US7538082B2 (en) 2001-04-24 2009-05-26 The General Hospital Corporation Methods and compositions for treating oral and esophageal lesions
US20030105016A1 (en) * 2001-09-06 2003-06-05 Podolsky Daniel K. Methods and compositions for treating vaginal, cervical, and uterine epithelial lesions
US20040171544A1 (en) * 2001-04-24 2004-09-02 Barker Nicholas P. Trefoil domain-containing polypeptides and uses thereof
US20060189526A1 (en) * 2002-04-24 2006-08-24 Podolsky Daniel K Compositions containing an intestinal trefoil peptide and a mucoadhesive
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CN1617739A (zh) * 2001-11-28 2005-05-18 综合医院公司 用于治疗呼吸道上皮病变的方法和组合物
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FI20022007A0 (fi) * 2002-11-08 2002-11-08 Juvantia Pharma Ltd Oy Oromukosaalinen valmiste ja menetelmä sen valmistamiseksi
US20040167194A1 (en) * 2003-02-20 2004-08-26 Randall Jared Lynn Methods of making 6-[(4,5-Dihydro-1H-imidazol-2-yl)amino-]-7-methyl-1H-benzimidazole-4-carbonitrile and its preferred salt form
US7777051B2 (en) * 2003-05-13 2010-08-17 Icagen, Inc. Asymmetric benzimidazoles and related compounds as potassium channel modulators
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US20130210876A1 (en) * 2010-01-21 2013-08-15 Allergan, Inc Alpha-2 adrenergic agonist having long duration of intraocular pressure-lowering effect
EP2736906B1 (en) 2011-07-25 2016-10-19 Allergan, Inc. N-(IMIDAZOLIDIN-2-YLIDENE)-HETEROCYCLOPENTA[b]PYRIDINE DERIVATIVES AS MODULATORS OF ALPHA 2 ADRENERGIC RECEPTORS
US9629847B2 (en) 2011-11-23 2017-04-25 Michael Leighton Compositions and methods for treating symptoms of inflammatory related conditions using a combination of an antihistamine and a stimulant
US9149474B2 (en) * 2011-11-23 2015-10-06 Michael Leighton Compositions and methods for treating symptoms of inflammatory related conditions using a combination of an antihistamine and a stimulant
US20150133516A1 (en) 2013-11-13 2015-05-14 Brian K. Adams Methods and Compositions for Treating ADHD
TW202021584A (zh) 2018-08-21 2020-06-16 美商歐樂根公司 α2 腎上腺素受體促效劑用於改善視力之用途
US11077053B2 (en) * 2018-08-21 2021-08-03 Allergan, Inc. Alpha-2-adrenergic receptor agonists for treatment of presbyopia, visual glare, visual starbursts, visual halos and night myopia
US20210260042A1 (en) 2020-02-20 2021-08-26 Allergan, Inc. Alpha-2-adrenergic receptor agonists for reducing redness and increasing whiteness in eyes and other ophthalmic purposes
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EP0775134A4 (en) * 1994-08-04 1997-08-13 Synaptic Pharma Corp NEW BENZIMIDAZOLE DERIVATIVES

Also Published As

Publication number Publication date
EP0736022B1 (en) 2003-09-24
SG49049A1 (en) 1998-05-18
NZ333371A (en) 2001-12-21
SK282566B6 (sk) 2002-10-08
PL315059A1 (en) 1996-09-30
FI962494A7 (fi) 1996-06-14
FI962494A0 (fi) 1996-06-14
US5691370A (en) 1997-11-25
ATE250598T1 (de) 2003-10-15
MY131696A (en) 2007-08-30
AU1306295A (en) 1995-07-03
NO962539D0 (no) 1996-06-14
CZ175196A3 (en) 1996-11-13
SK77196A3 (en) 1997-03-05
HU9601663D0 (en) 1996-08-28
EP0736022A1 (en) 1996-10-09
US5541210A (en) 1996-07-30
WO1995016685A1 (en) 1995-06-22
DE69433181T2 (de) 2004-07-01
FI962494L (fi) 1996-06-14
JPH09507216A (ja) 1997-07-22
RU2143430C1 (ru) 1999-12-27
CN1137794A (zh) 1996-12-11
CN1076352C (zh) 2001-12-19
CZ286816B6 (en) 2000-07-12
CA2179008A1 (en) 1995-06-22
ES2202352T3 (es) 2004-04-01
KR100385195B1 (ko) 2003-08-21
TW393469B (en) 2000-06-11
DE69433181D1 (de) 2003-10-30
US5478858A (en) 1995-12-26
CA2179008C (en) 1999-08-17
BR9408343A (pt) 1997-08-19
HUT76473A (en) 1997-09-29
NO309325B1 (no) 2001-01-15
AU699631B2 (en) 1998-12-10
PL180903B1 (pl) 2001-04-30
HU224016B1 (hu) 2005-04-28

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