NO964950L - Krystallinsk hydroklorid av (R)-(-)-2-{N-£4-(1,1-dioksido-3-okso-2,3-dihydro-benziso-tiazol-2-yl)-butyl|-aminometyl}-kroman - Google Patents

Krystallinsk hydroklorid av (R)-(-)-2-{N-£4-(1,1-dioksido-3-okso-2,3-dihydro-benziso-tiazol-2-yl)-butyl|-aminometyl}-kroman

Info

Publication number: NO964950L
Authority: NO; Norway
Prior art keywords: benzisothiazol; dioxido; chroman; aminomethyl; dihydro
Prior art date: 1995-11-22

Application number

NO964950A

Other languages

English (en)

Other versions

NO964950D0 (no

NO307340B1 (no

Inventor

Alfons Grunenberg

Oliver Brehm

Michael Conrad

Dietrich Seidel

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-11-22

Filing date

1996-11-21

Publication date

1997-05-23

1996-11-21 Application filed by Bayer Ag filed Critical Bayer Ag

1996-11-21 Publication of NO964950D0 publication Critical patent/NO964950D0/no

1997-05-23 Publication of NO964950L publication Critical patent/NO964950L/no

2000-03-20 Publication of NO307340B1 publication Critical patent/NO307340B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)

NO964950A 1995-11-22 1996-11-21 Krystallinsk hydroklorid av (R)-(-)-2-{N-[4-(1,1-dioksido-3- okso-2,3-dihydro-benzisotiazol-2-yl)-butyl]-aminometyl}-kroman, legemiddel inneholdende samme, samt fremstilling og anvendelse av samme NO307340B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19543478A DE19543478A1 (de)	1995-11-22	1995-11-22	Kristallines Hydrochlorid von {(R)-(-)-2- N-[4-(1,1-Dioxido-3-oxo-2,3-dihydrobenzisothiazol-2-yl)-buytl]-aminomethyl}-chroman

Publications (3)

Publication Number	Publication Date
NO964950D0 NO964950D0 (no)	1996-11-21
NO964950L true NO964950L (no)	1997-05-23
NO307340B1 NO307340B1 (no)	2000-03-20

Family

ID=7778081

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO964950A NO307340B1 (no)	1995-11-22	1996-11-21	Krystallinsk hydroklorid av (R)-(-)-2-{N-[4-(1,1-dioksido-3- okso-2,3-dihydro-benzisotiazol-2-yl)-butyl]-aminometyl}-kroman, legemiddel inneholdende samme, samt fremstilling og anvendelse av samme

Country Status (32)

Country	Link
US (1)	US5830908A (no)
EP (1)	EP0775704B1 (no)
JP (1)	JPH09143180A (no)
KR (1)	KR970027079A (no)
CN (1)	CN1086703C (no)
AR (1)	AR004961A1 (no)
AT (1)	ATE201872T1 (no)
AU (1)	AU712922B2 (no)
BR (1)	BR9605646A (no)
CA (1)	CA2190700A1 (no)
CZ (1)	CZ289730B6 (no)
DE (2)	DE19543478A1 (no)
DK (1)	DK0775704T3 (no)
EE (1)	EE9600183A (no)
ES (1)	ES2159342T3 (no)
GR (1)	GR3036505T3 (no)
HU (1)	HUP9603237A3 (no)
IL (1)	IL119647A (no)
MX (1)	MX9605741A (no)
MY (1)	MY132473A (no)
NO (1)	NO307340B1 (no)
NZ (1)	NZ299780A (no)
PL (1)	PL317090A1 (no)
PT (1)	PT775704E (no)
RU (1)	RU2181723C2 (no)
SG (1)	SG44989A1 (no)
SI (1)	SI0775704T1 (no)
SK (1)	SK150096A3 (no)
TR (1)	TR199600930A2 (no)
TW (1)	TW449595B (no)
UA (1)	UA45338C2 (no)
ZA (1)	ZA969753B (no)

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US5854217A (en) *	1992-09-28	1998-12-29	Bearsden Bio, Inc.	Allosteric modulators of the NMDA receptor and their use in the treatment of CNS disorders and enhancement of CNS function
US7407955B2 (en)	2002-08-21	2008-08-05	Boehringer Ingelheim Pharma Gmbh & Co., Kg	8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
US7501426B2 (en)	2004-02-18	2009-03-10	Boehringer Ingelheim International Gmbh	8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de)	2004-11-05	2006-05-11	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
DE102005035891A1 (de)	2005-07-30	2007-02-08	Boehringer Ingelheim Pharma Gmbh & Co. Kg	8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
PE20080251A1 (es)	2006-05-04	2008-04-25	Boehringer Ingelheim Int	Usos de inhibidores de dpp iv
KR101452915B1 (ko)	2006-05-04	2014-10-21	베링거 인겔하임 인터내셔날 게엠베하	다형태
EP1852108A1 (en)	2006-05-04	2007-11-07	Boehringer Ingelheim Pharma GmbH & Co.KG	DPP IV inhibitor formulations
NZ600126A (en) *	2007-08-17	2013-12-20	Boehringer Ingelheim Int	Purine derivatives for use in the treatment of fap-related diseases
PE20140960A1 (es)	2008-04-03	2014-08-15	Boehringer Ingelheim Int	Formulaciones que comprenden un inhibidor de dpp4
PE20100156A1 (es) *	2008-06-03	2010-02-23	Boehringer Ingelheim Int	Tratamiento de nafld
KR20190016601A (ko)	2008-08-06	2019-02-18	베링거 인겔하임 인터내셔날 게엠베하	메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
UY32030A (es)	2008-08-06	2010-03-26	Boehringer Ingelheim Int	"tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
WO2010018217A2 (en) *	2008-08-15	2010-02-18	Boehringer Ingelheim International Gmbh	Organic compounds for wound healing
MX2011002558A (es)	2008-09-10	2011-04-26	Boehringer Ingelheim Int	Terapia de combinacion para el tratamiento de diabetes y estados relacionados.
US20200155558A1 (en)	2018-11-20	2020-05-21	Boehringer Ingelheim International Gmbh	Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
AU2009331471B2 (en)	2008-12-23	2015-09-03	Boehringer Ingelheim International Gmbh	Salt forms of organic compound
AR074990A1 (es)	2009-01-07	2011-03-02	Boehringer Ingelheim Int	Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
KR20120107080A (ko)	2009-11-27	2012-09-28	베링거 인겔하임 인터내셔날 게엠베하	리나글립틴과 같은 ｄｐｐ－ｉｖ 억제제를 사용한 유전자형 검사된 당뇨병 환자의 치료
KR101927068B1 (ko)	2010-05-05	2018-12-10	베링거 인겔하임 인터내셔날 게엠베하	체중 감소 치료에 후속하는 dpp-4 억제제에 의한 순차적 병용 요법
KR20220025926A (ko)	2010-06-24	2022-03-03	베링거 인겔하임 인터내셔날 게엠베하	당뇨병 요법
AR083878A1 (es)	2010-11-15	2013-03-27	Boehringer Ingelheim Int	Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
CN103781788B (zh)	2011-07-15	2016-08-17	勃林格殷格翰国际有限公司	经取代的喹唑啉、其制备及其在药物组合物中的用途
US9555001B2 (en)	2012-03-07	2017-01-31	Boehringer Ingelheim International Gmbh	Pharmaceutical composition and uses thereof
JP6224084B2 (ja)	2012-05-14	2017-11-01	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	糸球体上皮細胞関連障害及び／又はネフローゼ症候群の治療に用いるｄｐｐ−４阻害薬としてのキサンチン誘導体
WO2013171166A1 (en)	2012-05-14	2013-11-21	Boehringer Ingelheim International Gmbh	A xanthine derivative as dpp-4 inhibitor for use in the treatment of sirs and/or sepsis
WO2013174767A1 (en)	2012-05-24	2013-11-28	Boehringer Ingelheim International Gmbh	A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
JP6615109B2 (ja)	2014-02-28	2019-12-04	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Ｄｐｐ−４阻害薬の医学的使用
MX390363B (es)	2016-06-10	2025-03-20	Boehringer Ingelheim Int	Combinacion de linagliptina y metformina

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US4748182A (en) *	1986-03-05	1988-05-31	Merrell Dow Pharmaceuticals Inc.	Aromatic 2-aminoalkyl-1,2-benzoisothiazol-3(2H)one-1,1-dioxide derivatives and their use as anti-hypertensive and anxiolytic agents
US5300523A (en) *	1988-07-28	1994-04-05	Bayer Aktiengesellschaft	Substituted aminomethyltetralins and their heterocyclic analogues
DE3901814A1 (de) *	1988-07-28	1990-02-01	Bayer Ag	Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE4138756A1 (de) *	1991-11-26	1993-05-27	Troponwerke Gmbh & Co Kg	Kombination mit neuroprotektiver wirkung

1995
- 1995-11-22 DE DE19543478A patent/DE19543478A1/de not_active Withdrawn
1996
- 1996-10-30 AR ARP960104981A patent/AR004961A1/es unknown
- 1996-11-11 DK DK96118043T patent/DK0775704T3/da active
- 1996-11-11 ES ES96118043T patent/ES2159342T3/es not_active Expired - Lifetime
- 1996-11-11 EP EP96118043A patent/EP0775704B1/de not_active Expired - Lifetime
- 1996-11-11 SI SI9630292T patent/SI0775704T1/xx unknown
- 1996-11-11 DE DE59607040T patent/DE59607040D1/de not_active Expired - Fee Related
- 1996-11-11 PT PT96118043T patent/PT775704E/pt unknown
- 1996-11-11 AT AT96118043T patent/ATE201872T1/de not_active IP Right Cessation
- 1996-11-14 AU AU71772/96A patent/AU712922B2/en not_active Ceased
- 1996-11-18 JP JP8322212A patent/JPH09143180A/ja not_active Withdrawn
- 1996-11-19 CA CA002190700A patent/CA2190700A1/en not_active Abandoned
- 1996-11-19 IL IL11964796A patent/IL119647A/xx not_active IP Right Cessation
- 1996-11-19 US US08/752,348 patent/US5830908A/en not_active Expired - Fee Related
- 1996-11-19 NZ NZ299780A patent/NZ299780A/en unknown
- 1996-11-20 SG SG1996011319A patent/SG44989A1/en unknown
- 1996-11-20 PL PL96317090A patent/PL317090A1/xx unknown
- 1996-11-20 TW TW085114226A patent/TW449595B/zh not_active IP Right Cessation
- 1996-11-21 NO NO964950A patent/NO307340B1/no not_active IP Right Cessation
- 1996-11-21 BR BR9605646A patent/BR9605646A/pt unknown
- 1996-11-21 KR KR1019960056088A patent/KR970027079A/ko not_active Ceased
- 1996-11-21 EE EE9600183A patent/EE9600183A/xx unknown
- 1996-11-21 UA UA96114365A patent/UA45338C2/uk unknown
- 1996-11-21 MY MYPI96004849A patent/MY132473A/en unknown
- 1996-11-21 ZA ZA969753A patent/ZA969753B/xx unknown
- 1996-11-21 MX MX9605741A patent/MX9605741A/es unknown
- 1996-11-21 SK SK1500-96A patent/SK150096A3/sk unknown
- 1996-11-21 CZ CZ19963428A patent/CZ289730B6/cs not_active IP Right Cessation
- 1996-11-22 HU HU9603237A patent/HUP9603237A3/hu unknown
- 1996-11-22 TR TR96/00930A patent/TR199600930A2/xx unknown
- 1996-11-22 RU RU96122395/04A patent/RU2181723C2/ru active
- 1996-11-22 CN CN96114587A patent/CN1086703C/zh not_active Expired - Fee Related
2001
- 2001-08-31 GR GR20010401365T patent/GR3036505T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
TW449595B (en)	2001-08-11
ATE201872T1 (de)	2001-06-15
ES2159342T3 (es)	2001-10-01
CA2190700A1 (en)	1997-05-23
MY132473A (en)	2007-10-31
EE9600183A (et)	1997-06-16
AU712922B2 (en)	1999-11-18
PT775704E (pt)	2001-09-28
AU7177296A (en)	1997-05-29
RU2181723C2 (ru)	2002-04-27
HU9603237D0 (en)	1997-01-28
CZ342896A3 (en)	1997-06-11
EP0775704A1 (de)	1997-05-28
NZ299780A (en)	1998-09-24
KR970027079A (ko)	1997-06-24
UA45338C2 (uk)	2002-04-15
ZA969753B (en)	1997-03-25
BR9605646A (pt)	1998-08-18
EP0775704B1 (de)	2001-06-06
CN1086703C (zh)	2002-06-26
DK0775704T3 (da)	2001-07-23
HUP9603237A2 (hu)	1998-01-28
DE59607040D1 (de)	2001-07-12
MX9605741A (es)	1997-05-31
IL119647A0 (en)	1997-02-18
TR199600930A2 (tr)	1997-06-21
NO964950D0 (no)	1996-11-21
IL119647A (en)	1999-12-22
NO307340B1 (no)	2000-03-20
SG44989A1 (en)	1997-12-19
CZ289730B6 (cs)	2002-03-13
GR3036505T3 (en)	2001-11-30
DE19543478A1 (de)	1997-05-28
US5830908A (en)	1998-11-03
HUP9603237A3 (en)	1998-12-28
JPH09143180A (ja)	1997-06-03
SI0775704T1 (en)	2001-08-31
AR004961A1 (es)	1999-04-07
PL317090A1 (en)	1997-05-26
SK150096A3 (en)	1997-08-06
CN1152574A (zh)	1997-06-25

Publication	Publication Date	Title
NO964950L (no)	1997-05-23	Krystallinsk hydroklorid av (R)-(-)-2-{N-£4-(1,1-dioksido-3-okso-2,3-dihydro-benziso-tiazol-2-yl)-butyl\|-aminometyl}-kroman
IT1289532B1 (it)	1998-10-15	Composti, di cloridrato di paroxetina e procedimenti per la loro preparazione
NO933093D0 (no)	1993-08-31	Monohydrat av 5-(2-(4-(1,2-benzisotiazol-3-yl)-1-piperazinyl)-etyl)-6-klor-1,3-dihydro-2h-indol-2-on hydroklorid
FI911096A7 (fi)	1991-09-07	N-(4-piperidyl) dihydrobenzofuran)karboxamid- eller n-(4-piperidyl)(dihydro-2h- benzopyran) karboxamidderivat.
ID17275A (id)	1997-12-18	N-[4-(heteroarilmetil)fenil]-heteroarilamina
EE9900053A (et)	1999-08-16	4-(5-metüül-3-fenüülisoksasool-4-üül)benseensulfoonamiidi kristalliline vorm
NO965084D0 (no)	1996-11-28	N-[3(3-cyanopyrazol[1,5-aÅpyrimidin-7-yl)fenylÅ-N-etyl-acetamid
PT1000048E (pt)	2003-03-31	Derivados substituidos do 1,2,3,4-tetrahidronaftaleno
PL334184A1 (en)	2000-02-14	Fungicidal compositions based on methyl n-(phenylacetyl)-n-(2,6-xylyl) alaninate
NO308537B1 (no)	2000-09-25	Antipsykotiske 4-(1H-indol-1-yl)-piperidinylderivater
NO975220D0 (no)	1997-11-13	Ny fremgangsmåte for fremstilling av ropivacainhydrokloridmonohydrat
ID21499A (id)	1999-06-17	Proses untuk memproduksi n-(4-fluorofenil)-n-(1-metiletil)-2-[(5-(trifluorometil)-1,3,4-tiadiazol-2-il)-oksi]-asetamida
NO20006350D0 (no)	2000-12-13	Derivater av 3-(2-okso-[1,3']bipyrrolidinyl-3-ylidenmetyl)- cephemer
FI955387L (fi)	1995-11-08	4(p-fluorifenyyli)-3-((3,4-(metyleenioksi)fenoksi)metyyli)-piperidiinin N-p-halobentsoyylimetyylijohdannaiset
NO982105D0 (no)	1998-05-08	Nye mellomprodukter og deres anvendelse for fremstilling av N,N'-broslÕtte bisindolylmaleimider
MA25653A1 (fr)	2002-12-31	Derives d'amides heterocycliques.
NO974846D0 (no)	1997-10-20	Fremgangsmåte for fremstilling av Form 1 Ranitidin-Hydroklorid
NO20003145D0 (no)	2000-06-16	FremgangsmÕte for fremstilling av paroxetine-hydroklorid
NO20013715L (no)	2001-09-17	Karbamatderivater av diaryl 1,3,4-oksadiazolon
DE69625379D1 (de)	2003-01-23	Salze des n-[4-oxo-2-(1h-tetrazoyl-5-yl)-4h-1-benzopyran-8-yl]-4-(4-phenylbutoxy)benzamids
EP0824453A4 (en)	1998-08-05	NEW USES OF HEPTAFLUORPROPAN
IT1275594B1 (it)	1997-08-06	Epimeri del (22rs)-n-(1,1,1-trifluoro-2-fenilprop-2-il)-3-osso -4-aza-5alfa-androst-1-ene-17beta-carbossammide
AU1479800A (en)	2000-06-05	Procedure for synthesis of N-(2(((5-((dialkilamino) methyl)-2- furanyl) methyl)thyo) ethyl)-N'- alkyl-2-nitro1,1 alkenediamines and their hydrochlorides
HK1016182A (en)	1999-10-29	Salts of n-[4-oxo-2-(1h-tetrazoyl-5-yl)-4h-1-benzopyran-8-yl]-4-(4-phenylbutoxy)benzamide

Legal Events

Date	Code	Title	Description
2003-06-30	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN MAY 2003