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NO875312D0 - Fremgangsmaate for fremstilling av alfa-l-aspartyl-l-fenylalanin-methylester med lav hygroskopisitet. - Google Patents

Fremgangsmaate for fremstilling av alfa-l-aspartyl-l-fenylalanin-methylester med lav hygroskopisitet.

Info

Publication number
NO875312D0
NO875312D0 NO875312A NO875312A NO875312D0 NO 875312 D0 NO875312 D0 NO 875312D0 NO 875312 A NO875312 A NO 875312A NO 875312 A NO875312 A NO 875312A NO 875312 D0 NO875312 D0 NO 875312D0
Authority
NO
Norway
Prior art keywords
methylestes
aspartyl
phenylalanine
procedure
low hygroscopicity
Prior art date
Application number
NO875312A
Other languages
English (en)
Other versions
NO875312L (no
Inventor
Ryuichi Mita
Toshio Katoh
Chojiro Higuchi
Takeshi Oura
Akihiro Yamaguchi
Original Assignee
Mitsui Toatsu Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals
Publication of NO875312D0 publication Critical patent/NO875312D0/no
Publication of NO875312L publication Critical patent/NO875312L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)
NO875312A 1986-12-19 1987-12-18 Fremgangsmaate for fremstilling av alfa-l-aspartyl-l-fenylalanin-methylester med lav hygroskopisitet. NO875312L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP61301469A JPH0832719B2 (ja) 1986-12-19 1986-12-19 吸湿性の小さいα−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの製造法

Publications (2)

Publication Number Publication Date
NO875312D0 true NO875312D0 (no) 1987-12-18
NO875312L NO875312L (no) 1988-06-20

Family

ID=17897271

Family Applications (1)

Application Number Title Priority Date Filing Date
NO875312A NO875312L (no) 1986-12-19 1987-12-18 Fremgangsmaate for fremstilling av alfa-l-aspartyl-l-fenylalanin-methylester med lav hygroskopisitet.

Country Status (9)

Country Link
US (1) US4962222A (no)
EP (1) EP0272062B1 (no)
JP (1) JPH0832719B2 (no)
KR (1) KR900008013B1 (no)
AU (1) AU589053B2 (no)
BR (1) BR8706921A (no)
CA (1) CA1318458C (no)
DE (1) DE3787082T2 (no)
NO (1) NO875312L (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0718306B1 (en) * 1994-12-22 2001-05-30 Holland Sweetener Company V.O.F. Crystallization of alpha-L-aspartyl-L-phenylalanine methyl ester from aqueous solution
DE69521110T2 (de) * 1994-12-22 2002-03-07 Holland Sweetener Co. V.O.F., Maastricht Crystallisierung vom Alpha-L-Aspartyl-L-phenylalanylmethylester aus wässrigen Lösungen
EP0751146B1 (en) * 1995-06-30 2002-03-13 Holland Sweetener Company V.o.F. Crystallization of alpha-L-aspartyl-L-phenylalanine methyl ester from aqueous solution
US6293692B1 (en) * 1999-11-05 2001-09-25 M. William Bowsher Multipurpose container structure

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE791544A (fr) * 1971-11-19 1973-05-17 Stamicarbon Preparation d'esters alkyliques de dipeptide
JPS4896557A (no) * 1972-03-22 1973-12-10
CA1028197A (en) * 1973-04-02 1978-03-21 Jeffrey H. Berg Concentrated liquid low calorie sweetener
US3933781A (en) * 1973-11-05 1976-01-20 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters
JPS5140069A (no) * 1974-10-02 1976-04-03 Hitachi Ltd
JPS5823380B2 (ja) * 1974-12-05 1983-05-14 味の素株式会社 ホルミルキノ ダツリホウ
JPS51113841A (en) * 1975-03-28 1976-10-07 Ajinomoto Co Inc Process for preparing lower alkyl esters of n-formyl-alpha -l-aspartyl-l-phenylalanine
US4088649A (en) * 1975-07-02 1978-05-09 Firmenich S.A. Process for preparing a diketo-piperazine
JPS5223001A (en) * 1975-08-14 1977-02-21 Ajinomoto Co Inc Process for elimination of formyl group
MX4704E (es) * 1976-12-27 1982-08-04 Monsanto Co Procedimiento mejorado para la preparacion de ester metilico de alfa-l-aspartil-l-fenilalanina
JPS58185545A (ja) * 1982-04-22 1983-10-29 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩の製法
GB2133409B (en) * 1983-01-13 1986-03-05 Erba Farmitalia Aspartame synthesis
GB8300810D0 (en) * 1983-01-13 1983-02-16 Erba Farmitalia Aspartame synthesis
JPH0631312B2 (ja) * 1983-03-18 1994-04-27 味の素株式会社 ジペプチド結晶及びその製造方法
JPS59219258A (ja) * 1983-05-28 1984-12-10 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル又はその塩酸塩の製法
JPH0613550B2 (ja) * 1983-06-03 1994-02-23 味の素株式会社 α―Ｌ―アスパルチル―Ｌ―フェニルアラニン―低級アルキルエステルの製造法
JPS59225152A (ja) * 1983-06-02 1984-12-18 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル又はその塩酸塩の製法
JPS59227849A (ja) * 1983-06-08 1984-12-21 Ajinomoto Co Inc Ｌ―α―アスパルチル―Ｌ―フェニルアラニンメチルエステル束状晶の晶析分離法
JPS6050200A (ja) * 1983-08-30 1985-03-19 Nippon Kokan Kk <Nkk> 金属ストリップのクリーニング洗浄液の浄化装置
JPS60174799A (ja) * 1984-02-21 1985-09-09 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの製造法
JPH0710878B2 (ja) * 1986-07-28 1995-02-08 東ソー株式会社 溶解性の改善されたα−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの製造方法
US4835303A (en) * 1986-08-12 1989-05-30 Toyo Soda Manufacturing Company, Ltd. Process for producing dry α-L-aspartyl-L-phenylalanine methyl ester
JPH07103154B2 (ja) * 1986-08-13 1995-11-08 東ソー株式会社 安定なα−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの製造方法
JPS6345298A (ja) * 1986-08-13 1988-02-26 Tosoh Corp 安定なα−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの製造方法

Also Published As

Publication number Publication date
JPH0832719B2 (ja) 1996-03-29
EP0272062A3 (en) 1990-04-25
NO875312L (no) 1988-06-20
EP0272062B1 (en) 1993-08-18
KR900008013B1 (ko) 1990-10-29
DE3787082T2 (de) 1994-04-07
CA1318458C (en) 1993-05-25
EP0272062A2 (en) 1988-06-22
BR8706921A (pt) 1988-07-26
AU8229187A (en) 1988-06-23
JPS63156800A (ja) 1988-06-29
KR880007561A (ko) 1988-08-27
DE3787082D1 (de) 1993-09-23
US4962222A (en) 1990-10-09
AU589053B2 (en) 1989-09-28

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