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NO834057L - Fremgangsmaate for fremstilling av derivater av piperidindion - Google Patents

Fremgangsmaate for fremstilling av derivater av piperidindion

Info

Publication number
NO834057L
NO834057L NO834057A NO834057A NO834057L NO 834057 L NO834057 L NO 834057L NO 834057 A NO834057 A NO 834057A NO 834057 A NO834057 A NO 834057A NO 834057 L NO834057 L NO 834057L
Authority
NO
Norway
Prior art keywords
derivatives
indion
piperid
preparing
procedure
Prior art date
Application number
NO834057A
Other languages
English (en)
Other versions
NO159852B (no
NO159852C (no
Inventor
Claude Bernhart
Werner Cautreels
Patrick Gautier
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of NO834057L publication Critical patent/NO834057L/no
Publication of NO159852B publication Critical patent/NO159852B/no
Publication of NO159852C publication Critical patent/NO159852C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57Nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
NO834057A 1982-11-08 1983-11-07 Analogifremgangsm te for fremstilling av terapeutisk aktive derivater av piperidindion. NO159852C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8218706A FR2535721A1 (fr) 1982-11-08 1982-11-08 Derives de la piperidinedione protecteurs du myocarde presentant une acticite antiarythmique, leur procede de preparation et les medicaments qui contiennent lesdits derives

Publications (3)

Publication Number Publication Date
NO834057L true NO834057L (no) 1984-05-09
NO159852B NO159852B (no) 1988-11-07
NO159852C NO159852C (no) 1989-02-15

Family

ID=9279000

Family Applications (1)

Application Number Title Priority Date Filing Date
NO834057A NO159852C (no) 1982-11-08 1983-11-07 Analogifremgangsm te for fremstilling av terapeutisk aktive derivater av piperidindion.

Country Status (29)

Country Link
US (1) US4721710A (no)
EP (1) EP0110755B1 (no)
JP (1) JPS59161377A (no)
KR (1) KR900006721B1 (no)
AT (1) ATE22561T1 (no)
AU (1) AU565519B2 (no)
CA (1) CA1221967A (no)
CS (1) CS244681B2 (no)
DD (3) DD229407A5 (no)
DE (1) DE3366623D1 (no)
DK (1) DK511383A (no)
ES (1) ES527091A0 (no)
FI (1) FI79536C (no)
FR (1) FR2535721A1 (no)
GR (1) GR78747B (no)
HU (1) HU191494B (no)
IE (1) IE56209B1 (no)
IL (1) IL70099A (no)
MA (1) MA19948A1 (no)
NO (1) NO159852C (no)
NZ (1) NZ206177A (no)
OA (1) OA07582A (no)
PH (1) PH20421A (no)
PL (3) PL139946B1 (no)
PT (1) PT77607B (no)
SG (1) SG1989G (no)
SU (3) SU1333237A3 (no)
YU (3) YU221183A (no)
ZA (1) ZA838065B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668689A (en) * 1984-07-19 1987-05-26 National Research Development Corporation Glutarimide derivatives for treating oestrogen-dependent tumors
US5238947A (en) * 1990-04-12 1993-08-24 University Of Georgia Research Foundation, Inc. Synthetic piperidinediones with cytostatic activity
US5463063A (en) * 1993-07-02 1995-10-31 Celgene Corporation Ring closure of N-phthaloylglutamines
DE19703763C1 (de) * 1997-02-01 1998-10-01 Gruenenthal Gmbh Thalidomidanaloge Verbindungen aus der Klasse der Piperidin-2,6-Dione
WO2012158795A1 (en) 2011-05-17 2012-11-22 Principia Biopharma Inc. Pyrazolopyrimidine derivatives as tyrosine kinase inhibitors
JP6068451B2 (ja) 2011-05-17 2017-01-25 ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・カリフオルニア キナーゼ阻害剤
PT2710005T (pt) 2011-05-17 2016-11-16 Principia Biopharma Inc Inibidores de tirosina-quinase
PT2892900T (pt) 2012-09-10 2017-11-06 Principia Biopharma Inc Compostos de pirazolopirimidina como inibidores de cinase
US8957080B2 (en) 2013-04-09 2015-02-17 Principia Biopharma Inc. Tyrosine kinase inhibitors
PT3107544T (pt) 2014-02-21 2021-01-05 Principia Biopharma Inc Sais e forma sólida de um inibidor de btk
CA2970723C (en) 2014-12-18 2023-09-05 Principia Biopharma Inc. Treatment of pemphigus
EP3313839A1 (en) 2015-06-24 2018-05-02 Principia Biopharma Inc. Tyrosine kinase inhibitors
IL293621B2 (en) 2016-06-29 2023-09-01 Principia Biopharma Inc Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[4,3-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4 -Methyl-4-[4-(oxane-3-yl)piperazine-1-yl)penta-2-ananitrile
CA3154257A1 (en) 2019-10-14 2021-04-22 Principia Biopharma Inc. Methods for treating immune thrombocytopenia by administering (r)-2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile
AU2021209884A1 (en) 2020-01-22 2022-09-15 Principia Biopharma Inc. Crystalline forms of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2664424A (en) * 1953-12-29 Dioxo-piperidines
GB1455687A (en) * 1972-12-28 1976-11-17 Aspro Nicholas Ltd Pharmacologically active 3-phenyl-3-aminoalkyl-2,6-dioxo-hydro genated pyridines
FR2467200A1 (fr) * 1979-10-11 1981-04-17 Clin Midy Derives du pyrrole actifs sur les troubles du rythme cardiovasculaire

Also Published As

Publication number Publication date
PL140992B1 (en) 1987-06-30
PL249749A1 (en) 1985-03-12
NO159852B (no) 1988-11-07
ZA838065B (en) 1984-06-27
MA19948A1 (fr) 1984-07-01
KR840006641A (ko) 1984-12-01
ES8406070A1 (es) 1984-07-01
GR78747B (no) 1984-10-02
EP0110755B1 (fr) 1986-10-01
IE832581L (en) 1984-05-08
FI79536C (fi) 1990-01-10
DE3366623D1 (en) 1986-11-06
DK511383A (da) 1984-05-09
FI834087A0 (fi) 1983-11-08
IL70099A (en) 1987-10-20
SU1316558A3 (ru) 1987-06-07
DD219770A5 (de) 1985-03-13
FR2535721B1 (no) 1985-05-17
SU1333238A3 (ru) 1987-08-23
JPS59161377A (ja) 1984-09-12
CA1221967A (en) 1987-05-19
SU1333237A3 (ru) 1987-08-23
US4721710A (en) 1988-01-26
NZ206177A (en) 1985-11-08
PL249750A1 (en) 1985-03-12
FI79536B (fi) 1989-09-29
IE56209B1 (en) 1991-05-22
CS244681B2 (en) 1986-08-14
EP0110755A1 (fr) 1984-06-13
AU2089883A (en) 1984-05-17
OA07582A (fr) 1985-03-31
DD229407A5 (de) 1985-11-06
ATE22561T1 (de) 1986-10-15
FI834087L (fi) 1984-05-09
PL139946B1 (en) 1987-03-31
DD229402A5 (de) 1985-11-06
KR900006721B1 (ko) 1990-09-20
PL140021B1 (en) 1987-03-31
ES527091A0 (es) 1984-07-01
YU221183A (en) 1986-06-30
SG1989G (en) 1989-06-02
PL244462A1 (en) 1985-02-13
PH20421A (en) 1987-01-05
AU565519B2 (en) 1987-09-17
PT77607B (fr) 1986-03-18
PT77607A (fr) 1983-12-01
NO159852C (no) 1989-02-15
HU191494B (en) 1987-02-27
IL70099A0 (en) 1984-01-31
YU184185A (en) 1986-06-30
YU184285A (en) 1986-06-30
FR2535721A1 (fr) 1984-05-11
DK511383D0 (da) 1983-11-08

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