NO306676B1 - Nye 4-oksocykliske urinstoffer som er nyttige som antiarytmiske og antifibrillatoriske midler - Google Patents

Nye 4-oksocykliske urinstoffer som er nyttige som antiarytmiske og antifibrillatoriske midler Download PDF

Info

Publication number: NO306676B1
Authority: NO; Norway
Prior art keywords: arrhythmias; new; oxocyclic; antiarrhythmic; lubricants
Prior art date: 1991-08-14

Application number

NO940497A

Other languages

English (en)

Norwegian (no)

Other versions

NO940497L (no

NO940497D0 (no

Inventor

Jr Stanford Salvatore Pelosi

Chia-Nien Yu

Mark Arthur Calcagno

Original Assignee

Procter & Gamble Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-08-14

Filing date

1994-02-14

Publication date

1999-12-06

1994-02-14 Application filed by Procter & Gamble Pharma filed Critical Procter & Gamble Pharma

1994-02-14 Publication of NO940497L publication Critical patent/NO940497L/no

1994-02-14 Publication of NO940497D0 publication Critical patent/NO940497D0/no

1999-12-06 Publication of NO306676B1 publication Critical patent/NO306676B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/80—Two oxygen atoms, e.g. hydantoin with hetero atoms or acyl radicals directly attached to ring nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Pharmacology & Pharmacy (AREA)
Cardiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicinal Preparation (AREA)
Hydrogenated Pyridines (AREA)

NO940497A 1991-08-14 1994-02-14 Nye 4-oksocykliske urinstoffer som er nyttige som antiarytmiske og antifibrillatoriske midler NO306676B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US74486791A	1991-08-14	1991-08-14
PCT/US1992/006684 WO1993004061A1 (en)	1991-08-14	1992-08-10	Novel 4-oxocyclic ureas useful as antiarrhythmic and antifibrillatory agents

Publications (3)

Publication Number	Publication Date
NO940497L NO940497L (no)	1994-02-14
NO940497D0 NO940497D0 (no)	1994-02-14
NO306676B1 true NO306676B1 (no)	1999-12-06

Family

ID=24994275

Family Applications (5)

Application Number	Title	Priority Date	Filing Date
NO940497A NO306676B1 (no)	1991-08-14	1994-02-14	Nye 4-oksocykliske urinstoffer som er nyttige som antiarytmiske og antifibrillatoriske midler
NO19992897A NO310148B1 (no)	1991-08-14	1999-06-14	Nye 4-oksocykliske urinstoffer som er nyttige som antiarytmiske og antifibrillatoriske midler
NO19992898A NO310145B1 (no)	1991-08-14	1999-06-14	Nye 4-oksocykliske urinstoffer som er nyttige som antiarytmiske og antifibrillatoriske midler
NO19992899A NO310146B1 (no)	1991-08-14	1999-06-14	Nye 4-oksocykliske urinstoffer som er nyttige som antiarytmiske og antifibrillatoriske midler
NO19992900A NO310147B1 (no)	1991-08-14	1999-06-14	Nye 4-oksocykliske urinstoffer som er nyttige som antiarytmiske og antifibrillatoriske midler

Family Applications After (4)

Application Number	Title	Priority Date	Filing Date
NO19992897A NO310148B1 (no)	1991-08-14	1999-06-14	Nye 4-oksocykliske urinstoffer som er nyttige som antiarytmiske og antifibrillatoriske midler
NO19992898A NO310145B1 (no)	1991-08-14	1999-06-14	Nye 4-oksocykliske urinstoffer som er nyttige som antiarytmiske og antifibrillatoriske midler
NO19992899A NO310146B1 (no)	1991-08-14	1999-06-14	Nye 4-oksocykliske urinstoffer som er nyttige som antiarytmiske og antifibrillatoriske midler
NO19992900A NO310147B1 (no)	1991-08-14	1999-06-14	Nye 4-oksocykliske urinstoffer som er nyttige som antiarytmiske og antifibrillatoriske midler

Country Status (27)

Country	Link
US (1)	US5462940A (de)
EP (2)	EP0598061B1 (de)
JP (1)	JP3040473B2 (de)
KR (2)	KR100273605B1 (de)
AT (1)	ATE220675T1 (de)
AU (1)	AU668360B2 (de)
BR (1)	BR9206369A (de)
CA (1)	CA2115427C (de)
CZ (1)	CZ282368B6 (de)
DE (1)	DE69232681T2 (de)
DK (1)	DK0598061T3 (de)
ES (1)	ES2180537T3 (de)
FI (1)	FI109696B (de)
HK (1)	HK1048806A1 (de)
HU (1)	HU221317B1 (de)
IL (1)	IL102793A (de)
MX (1)	MX9204730A (de)
MY (1)	MY109205A (de)
NO (5)	NO306676B1 (de)
NZ (1)	NZ243938A (de)
PH (1)	PH31451A (de)
PL (2)	PL170961B1 (de)
PT (1)	PT100777B (de)
RU (2)	RU2130935C1 (de)
SK (1)	SK282656B6 (de)
TW (1)	TW232691B (de)
WO (1)	WO1993004061A1 (de)

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US6083945A (en) *	1995-06-07	2000-07-04	The Procter & Gamble Company	Cyclic ureas useful as antiarrhythmic and antifibrillatory agents
US6262068B1 (en)	1997-02-21	2001-07-17	Bristol-Myers Squibb Company	Lactam derivatives as antiarrhythmic agents
AU6320998A (en)	1997-02-21	1998-09-09	Bristol-Myers Squibb Company	Benzoic acid derivatives and related compounds as antiarrhythmic agents
US6048877A (en) *	1997-02-21	2000-04-11	Bristol-Myers Squibb Company	Tetralone derivatives as antiarrhythmic agents
US6664250B2 (en)	1998-01-20	2003-12-16	Bristol-Myers Squibb Co.	Lactam derivatives as antiarrhythmic agents
US6413785B1 (en)	1998-02-20	2002-07-02	The Procter & Gamble Co.	Solid phase synthesis of 1-aminohydantoins
TR200003136T2 (tr) *	1998-04-29	2001-03-21	The Procter & Gamble Company	1,3-İki ikameli-4-oksosiklik ürelerin yapımı ile ilgili yöntem.
RU2194706C2 (ru) *	1998-04-29	2002-12-20	Дзе Проктер Энд Гэмбл Компани	Способ получения дигидрохлорида 1-[[[5-(4-хлорфенил)-2-фуранил]метилен]амино]-3-[4-(4-метил-1-пиперазинил) бутил]-2,4-имидазолидиндиона
SE0100733D0 (sv) *	2001-03-05	2001-03-05	Medivir Ab	Non-nucleoside reverse transcriptase inhibitors
CN100443473C (zh) *	2005-04-30	2008-12-17	中国药科大学	1-氨基-3-(氮杂环基烷基)-2,4-咪唑二酮的合成方法
EP1948679B1 (de) *	2005-10-18	2010-05-05	Seoul National University Industry Foundation	Verfahren zur herstellung eines rekombinanten peptids aus spinnengift, und das peptid enthaltende analgetische zusammensetzung
TW200840578A (en) *	2006-12-15	2008-10-16	Procter & Gamble	Compositions of azimilide dihydrochloride
US20120178762A1 (en)	2006-12-15	2012-07-12	Warner Chilcott Company, Llc	Compositions of azimilide dihydrochloride
CN101735202B (zh) *	2009-12-17	2012-05-30	天津药物研究院	盐酸阿齐利特的晶型ⅰ及其制备方法和用途
CN101735203B (zh) *	2009-12-17	2012-05-23	天津药物研究院	盐酸阿齐利特的晶型ⅱ及其制备方法和用途
CN101735205B (zh) *	2009-12-17	2013-05-15	天津药物研究院	盐酸阿齐利特的晶型ⅴ及其制备方法和用途

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1992
- 1992-08-10 PL PL92302377A patent/PL170961B1/pl unknown
- 1992-08-10 BR BR9206369A patent/BR9206369A/pt not_active Application Discontinuation
- 1992-08-10 JP JP5504376A patent/JP3040473B2/ja not_active Expired - Fee Related
- 1992-08-10 HU HU9400396A patent/HU221317B1/hu unknown
- 1992-08-10 AU AU24717/92A patent/AU668360B2/en not_active Expired
- 1992-08-10 AT AT92918467T patent/ATE220675T1/de active
- 1992-08-10 DK DK92918467T patent/DK0598061T3/da active
- 1992-08-10 DE DE69232681T patent/DE69232681T2/de not_active Expired - Lifetime
- 1992-08-10 SK SK171-94A patent/SK282656B6/sk not_active IP Right Cessation
- 1992-08-10 KR KR1019940700427A patent/KR100273605B1/ko not_active Expired - Fee Related
- 1992-08-10 RU RU94015844A patent/RU2130935C1/ru not_active IP Right Cessation
- 1992-08-10 EP EP92918467A patent/EP0598061B1/de not_active Expired - Lifetime
- 1992-08-10 PL PL92314009A patent/PL170984B1/pl unknown
- 1992-08-10 WO PCT/US1992/006684 patent/WO1993004061A1/en not_active Ceased
- 1992-08-10 RU RU99101341/04A patent/RU2221788C2/ru not_active IP Right Cessation
- 1992-08-10 EP EP02075117A patent/EP1231208A3/de not_active Withdrawn
- 1992-08-10 ES ES92918467T patent/ES2180537T3/es not_active Expired - Lifetime
- 1992-08-10 CZ CZ94306A patent/CZ282368B6/cs not_active IP Right Cessation
- 1992-08-10 CA CA002115427A patent/CA2115427C/en not_active Expired - Lifetime
- 1992-08-12 IL IL10279392A patent/IL102793A/en not_active IP Right Cessation
- 1992-08-12 PH PH44800A patent/PH31451A/en unknown
- 1992-08-13 NZ NZ243938A patent/NZ243938A/en unknown
- 1992-08-14 PT PT100777A patent/PT100777B/pt not_active IP Right Cessation
- 1992-08-14 MY MYPI92001463A patent/MY109205A/en unknown
- 1992-08-14 MX MX9204730A patent/MX9204730A/es unknown
- 1992-08-22 TW TW081106647A patent/TW232691B/zh not_active IP Right Cessation
1994
- 1994-02-11 FI FI940657A patent/FI109696B/fi not_active IP Right Cessation
- 1994-02-14 NO NO940497A patent/NO306676B1/no not_active IP Right Cessation
- 1994-06-03 US US08/275,461 patent/US5462940A/en not_active Expired - Lifetime
1999
- 1999-06-14 NO NO19992897A patent/NO310148B1/no not_active IP Right Cessation
- 1999-06-14 NO NO19992898A patent/NO310145B1/no not_active IP Right Cessation
- 1999-06-14 NO NO19992899A patent/NO310146B1/no not_active IP Right Cessation
- 1999-06-14 NO NO19992900A patent/NO310147B1/no not_active IP Right Cessation
- 1999-11-01 KR KR1019997010110A patent/KR100295946B1/ko not_active Expired - Fee Related
2003
- 2003-01-30 HK HK03100753.4A patent/HK1048806A1/en unknown

Also Published As

Publication number	Publication date
CZ30694A3 (en)	1995-01-18
PT100777B (pt)	1999-07-30
NO992900L (no)	1994-02-14
NO310145B1 (no)	2001-05-28
DE69232681T2 (de)	2003-02-13
NO992898L (no)	1994-02-14
US5462940A (en)	1995-10-31
NO992899D0 (no)	1999-06-14
JP3040473B2 (ja)	2000-05-15
PT100777A (pt)	1993-12-31
FI940657A0 (fi)	1994-02-11
EP0598061A1 (de)	1994-05-25
RU2221788C2 (ru)	2004-01-20
PH31451A (en)	1998-11-03
FI940657A7 (fi)	1994-02-11
HUT70152A (en)	1995-09-28
CA2115427A1 (en)	1993-03-04
BR9206369A (pt)	1995-05-30
NO992897D0 (no)	1999-06-14
CZ282368B6 (cs)	1997-07-16
NO940497L (no)	1994-02-14
NO992899L (no)	1994-02-14
SK282656B6 (sk)	2002-11-06
NO992900D0 (no)	1999-06-14
DE69232681D1 (de)	2002-08-22
ES2180537T3 (es)	2003-02-16
JPH06509804A (ja)	1994-11-02
NO310147B1 (no)	2001-05-28
AU2471792A (en)	1993-03-16
NZ243938A (en)	1996-10-28
PL170961B1 (en)	1997-02-28
HU221317B1 (en)	2002-09-28
IL102793A (en)	1996-12-05
HK1048806A1 (en)	2003-04-17
IL102793A0 (en)	1993-01-31
MX9204730A (es)	1994-03-31
EP0598061B1 (de)	2002-07-17
DK0598061T3 (da)	2002-11-11
PL170984B1 (pl)	1997-02-28
EP1231208A3 (de)	2003-12-10
NO940497D0 (no)	1994-02-14
NO992897L (no)	1994-02-14
EP1231208A2 (de)	2002-08-14
AU668360B2 (en)	1996-05-02
WO1993004061A1 (en)	1993-03-04
HU9400396D0 (en)	1994-05-30
SK17194A3 (en)	1995-03-08
RU2130935C1 (ru)	1999-05-27
CA2115427C (en)	2000-05-02
ATE220675T1 (de)	2002-08-15
NO310148B1 (no)	2001-05-28
MY109205A (en)	1996-12-31
KR100295946B1 (ko)	2001-07-03
NO992898D0 (no)	1999-06-14
KR100273605B1 (ko)	2000-12-15
FI109696B (fi)	2002-09-30
NO310146B1 (no)	2001-05-28
TW232691B (de)	1994-10-21

Publication	Publication Date	Title
EP0920438B1 (de)	2001-06-20	N6-heterocyclisch-substituierte adenosin-derivate
NO306676B1 (no)	1999-12-06	Nye 4-oksocykliske urinstoffer som er nyttige som antiarytmiske og antifibrillatoriske midler
US3949089A (en)	1976-04-06	Substituted guanidine compounds as antifibrillatory agents
AU761521C (en)	2004-01-22	Pharmaceutical composition comprising a combination of dextro- and laevo- isomers of sotalol
US5175187A (en)	1992-12-29	Synergistic compositions for the treatment of coronary insufficiency and methods of use thereof
RU2142461C1 (ru)	1999-12-10	Циклические соединения мочевины, фармацевтическая композиция и способ лечения
EA007952B1 (ru)	2007-02-27	Применение ирбесартана для изготовления лекарств, которые пригодны для предупреждения или лечения лёгочной артериальной гипертензии
JPH08511014A (ja)	1996-11-19	クラス▲ｉｉｉ▼抗不整脈薬としてのｎ−［［１−［４−（４−フルオロフェノキシ）ブチル］４−ピペリジニル］−ｎ−メチル−アミノ］−２−ベンゾチアゾロール
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NO300807B1 (no)	1997-07-28	Cykliske uretaner som er nyttige som antiarytmiske og antifibrillatoriske midler
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