NO304488B1 - 5-leddede heteroaryloksazolidinoner, anvendelse av disse for fremstilling av legemidler samt legemiddel inneholdende forbindelsen - Google Patents

5-leddede heteroaryloksazolidinoner, anvendelse av disse for fremstilling av legemidler samt legemiddel inneholdende forbindelsen

Info

Publication number: NO304488B1
Authority: NO; Norway
Prior art keywords: drugs; heteroaryloxazolidinones; membered; manufacture; compound
Prior art date: 1994-07-20

Application number

NO952866A

Other languages

English (en)

Norwegian (no)

Other versions

NO952866L (no

NO952866D0 (no

Inventor

Bernd Riedl

Dieter Hobich

Andreas Stolle

Hanno Wild

Rainer Endermann

Klaus Dieter Bremm

Hein-Peter Kroll

Harald Labischinski

Klaus Schaller

Hans-Otto Werling

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-07-20

Filing date

1995-07-19

Publication date

1998-12-28

1995-07-19 Application filed by Bayer Ag filed Critical Bayer Ag

1995-07-19 Publication of NO952866D0 publication Critical patent/NO952866D0/no

1996-01-22 Publication of NO952866L publication Critical patent/NO952866L/no

1998-12-28 Publication of NO304488B1 publication Critical patent/NO304488B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/48—Nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Thiazole And Isothizaole Compounds (AREA)

NO952866A 1994-07-20 1995-07-19 5-leddede heteroaryloksazolidinoner, anvendelse av disse for fremstilling av legemidler samt legemiddel inneholdende forbindelsen NO304488B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4425613A DE4425613A1 (de)	1994-07-20	1994-07-20	5-gliedrige Heteroaryl-oxazolidinone

Publications (3)

Publication Number	Publication Date
NO952866D0 NO952866D0 (no)	1995-07-19
NO952866L NO952866L (no)	1996-01-22
NO304488B1 true NO304488B1 (no)	1998-12-28

Family

ID=6523633

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO952866A NO304488B1 (no)	1994-07-20	1995-07-19	5-leddede heteroaryloksazolidinoner, anvendelse av disse for fremstilling av legemidler samt legemiddel inneholdende forbindelsen

Country Status (28)

Country	Link
US (1)	US5698574A (sk)
EP (1)	EP0693491A1 (sk)
JP (1)	JPH0853443A (sk)
KR (1)	KR960004343A (sk)
CN (1)	CN1121919A (sk)
AU (1)	AU695661B2 (sk)
BG (1)	BG99791A (sk)
CA (1)	CA2154026A1 (sk)
CO (1)	CO4410193A1 (sk)
CZ (1)	CZ187395A3 (sk)
DE (1)	DE4425613A1 (sk)
EE (1)	EE9500044A (sk)
FI (1)	FI953476L (sk)
HR (1)	HRP950391A2 (sk)
HU (1)	HUT74003A (sk)
IL (1)	IL114622A (sk)
MA (1)	MA23621A1 (sk)
NO (1)	NO304488B1 (sk)
NZ (1)	NZ272596A (sk)
PE (1)	PE35896A1 (sk)
PL (1)	PL309685A1 (sk)
RO (1)	RO115161B1 (sk)
RU (1)	RU95113086A (sk)
SK (1)	SK91695A3 (sk)
SV (1)	SV1995000042A (sk)
TN (1)	TNSN95083A1 (sk)
YU (1)	YU49195A (sk)
ZA (1)	ZA956015B (sk)

Families Citing this family (69)

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DE4425609A1 (de) *	1994-07-20	1996-01-25	Bayer Ag	Benzofuranyl- und Benzothienyloxazolidinone
DE69615002T2 (de) *	1995-02-03	2002-06-13	Pharmacia & Upjohn Co., Kalamazoo	Durch hetero-aromatische ring substituierte phenyloxazolidinone als antimikrobielles mittel
US6124334A (en) *	1995-02-03	2000-09-26	Pharmacia & Upjohn Company	Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials
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DE19601264A1 (de) *	1996-01-16	1997-07-17	Bayer Ag	Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone
GB9601666D0 (en) *	1996-01-27	1996-03-27	Zeneca Ltd	Chemical compounds
DE19604223A1 (de) *	1996-02-06	1997-08-07	Bayer Ag	Neue substituierte Oxazolidinone
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GB9702213D0 (en)	1996-02-24	1997-03-26	Zeneca Ltd	Chemical compounds
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GB9717807D0 (en) *	1997-08-22	1997-10-29	Zeneca Ltd	Chemical compounds
GB9717804D0 (en)	1997-08-22	1997-10-29	Zeneca Ltd	Chemical compounds
GB9725244D0 (en)	1997-11-29	1998-01-28	Zeneca Ltd	Chemical compounds
US7002020B1 (en)	1998-01-23	2006-02-21	Pharmacia & Upjohn Company	Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6562844B2 (en)	1998-01-23	2003-05-13	Pharmacia & Upjohn Company	Oxazolidinone combinatorial libraries, compositions and methods of preparation
JP2002501059A (ja)	1998-01-23	2002-01-15	ファルマシア・アンド・アップジョン・カンパニー	オキサゾリジノンの組合せライブラリー、組成物および調製方法
US6262044B1 (en) *	1998-03-12	2001-07-17	Novo Nordisk A/S	Modulators of protein tyrosine phosphatases (PTPASES)
US6221902B1 (en)	1998-05-12	2001-04-24	American Home Products Corporation	Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
US6110962A (en) *	1998-05-12	2000-08-29	American Home Products Corporation	11-aryl-benzo[B]naphtho[2,3-D]furans and 11-aryl-benzo[B]naphtho[2,3-D]thiophenes useful in the treatment of insulin resistance and hyperglycemia
HRP20000767A2 (en) *	1998-05-12	2001-10-31	American Home Prod	Benzothiophenes, benzofurans and indoles useful in the treatment of insulin resistance and hyperglycemia
US6232322B1 (en)	1998-05-12	2001-05-15	American Home Products Corporation	Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
US6251936B1 (en)	1998-05-12	2001-06-26	American Home Products Corporation	Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia
AU4072799A (en)	1998-05-12	1999-12-13	American Home Products Corporation	2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia
US6110963A (en) *	1998-05-12	2000-08-29	American Home Products Corporation	Aryl-oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
US6699896B1 (en)	1998-05-12	2004-03-02	Wyeth	Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
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NZ508174A (en)	1998-06-05	2003-10-31	Astrazeneca Ab	Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
EA003274B1 (ru) *	1998-07-14	2003-04-24	Фармация Энд Апджон Компани	Оксазолидиноны в качестве активного вещества при лечении инфекционных глазных болезней
US6420349B1 (en)	1998-08-24	2002-07-16	Bristol-Myers Squibb Company	Isoxazolinone antibacterial agents
AR020660A1 (es) *	1998-09-30	2002-05-22	Alcon Lab Inc	Composiciones antibioticas para el tratamiento de ojos, oidos y nariz
JP2002535680A (ja)	1999-01-27	2002-10-22	ファルマシア・アンド・アップジョン・カンパニー	延長因子ｐ活性モジュレーターのアッセイ方法
US6310081B1 (en)	1999-05-10	2001-10-30	American Home Products Corporation	Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
GB9928568D0 (en)	1999-12-03	2000-02-02	Zeneca Ltd	Chemical compounds
US6514529B2 (en)	2000-03-22	2003-02-04	Pharmacia & Upjohn Company	Oxazolidinone tablet formulation
MY127336A (en)	2000-03-22	2006-11-30	Upjohn Co	Container for linezolid iv solution
GB0009803D0 (en) *	2000-04-25	2000-06-07	Astrazeneca Ab	Chemical compounds
US6465456B2 (en)	2000-06-29	2002-10-15	Bristol-Myers Squibb Company	Isoxazolinone antibacterial agents
US6544991B2 (en)	2000-06-30	2003-04-08	Pharmacia & Upjohn Company	Compositions and methods for treating bacterial infections
PE20020300A1 (es) *	2000-08-22	2002-05-10	Pharmacia Corp	Composicion de solucion de un farmaco antibiotico a base de oxazolidinona con mejoramiento de la carga de farmaco
WO2002018354A1 (en) *	2000-08-31	2002-03-07	Abbott Laboratories	Oxazolidinones and their use as antibacterial agents
AR031135A1 (es)	2000-10-10	2003-09-10	Upjohn Co	Composiciones de antibiotico topico para el tratamiento de infecciones oculares
ES2256331T3 (es)	2000-12-21	2006-07-16	PHARMACIA & UPJOHN COMPANY LLC	Derivados de quinolina antimicrobianos y uso de los mismos para tratar infecciones bacterianas.
GB0118407D0 (en) *	2001-07-27	2001-09-19	Cipla Ltd	Oxazolidinone derivatives as antibacterial agents
JP2003192773A (ja) *	2001-12-26	2003-07-09	Mitsui Chemicals Inc	生体吸収性ポリヒドロキシカルボン酸及びその製造法
TW200302095A (en) *	2002-01-25	2003-08-01	Upjohn Co	Oxazolidinone cotherapy
AR038576A1 (es) *	2002-02-22	2005-01-19	Pharmacia Corp	Formulaciones de drogas antibioticas oftalmicas que contienen un compuesto de ciclodextrina y cloruro de cetil piridinio
US7141588B2 (en) *	2002-02-25	2006-11-28	Pfizer, Inc.	N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
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EP1490059A1 (en) *	2002-03-29	2004-12-29	Pharmacia & Upjohn Company LLC	Parenteral, intravenous, and oral administration of oxazolidinones for treating diabetic foot infections
MXPA05001558A (es) *	2002-08-12	2005-09-08	Pharmacia & Upjohn Co Llc	N-aril-2-oxazolidinonas y sus derivados.
AR042086A1 (es) *	2002-11-21	2005-06-08	Upjohn Co	N-aril-2- oxazolidinon -5- carboxamidas y sus derivados, usados como agentes antibacterianos
MXPA05005651A (es) *	2002-11-28	2005-07-27	Astrazeneca Ab	Derivados de oxazolidinona y/o isoxazolina como agentes antibacterianos.
GB0229526D0 (en) *	2002-12-19	2003-01-22	Astrazeneca Ab	Chemical compounds
US20040170686A1 (en) *	2003-01-31	2004-09-02	Fredrickson Jennifer K.	Suspension vehicle for coated drug particles
CA2515269A1 (en) *	2003-02-07	2004-08-19	Warner-Lambert Company Llc	Oxazolidinone derivatives n-substituted by a bicyclic ring, for use as antibacterial agents
MXPA05007724A (es) *	2003-02-07	2005-09-30	Warner Lambert Co	Agentes antibacterianos.
US20040191326A1 (en) *	2003-03-31	2004-09-30	Reo Joseph P.	Taste-masking vehicle for coated oxazolidinone particles
US20040204463A1 (en) *	2003-04-01	2004-10-14	Harris Christina Renee	N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
WO2005019214A1 (en) *	2003-08-25	2005-03-03	Warner-Lambert Company Llc	Novel antimicrobial aryloxazolidinone compounds
US7304050B2 (en) *	2003-09-16	2007-12-04	Pfizer Inc.	Antibacterial agents
AU2006231919A1 (en)	2005-04-06	2006-10-12	Pharmacia & Upjohn Company Llc	7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
WO2008021338A2 (en) *	2006-08-15	2008-02-21	Wyeth	Tricyclic oxazolidone derivatives useful as pr modulators
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WO2013182070A1 (zh) *	2012-06-08	2013-12-12	四川贝力克生物技术有限责任公司	一种用于预防或治疗分支杆菌疾病的药物

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1994
- 1994-07-20 DE DE4425613A patent/DE4425613A1/de not_active Withdrawn
1995
- 1995-07-07 EP EP95110629A patent/EP0693491A1/de not_active Withdrawn
- 1995-07-10 HR HRP4425613.2A patent/HRP950391A2/hr not_active Application Discontinuation
- 1995-07-11 RO RO95-01295A patent/RO115161B1/ro unknown
- 1995-07-13 AU AU24988/95A patent/AU695661B2/en not_active Ceased
- 1995-07-17 IL IL11462295A patent/IL114622A/xx active IP Right Grant
- 1995-07-17 CA CA002154026A patent/CA2154026A1/en not_active Abandoned
- 1995-07-17 US US08/503,183 patent/US5698574A/en not_active Expired - Fee Related
- 1995-07-18 FI FI953476A patent/FI953476L/fi unknown
- 1995-07-18 NZ NZ272596A patent/NZ272596A/en unknown
- 1995-07-18 JP JP7203904A patent/JPH0853443A/ja active Pending
- 1995-07-18 EE EE9500044A patent/EE9500044A/xx unknown
- 1995-07-18 BG BG99791A patent/BG99791A/bg unknown
- 1995-07-18 CO CO95031767A patent/CO4410193A1/es unknown
- 1995-07-18 PL PL95309685A patent/PL309685A1/xx unknown
- 1995-07-19 MA MA23960A patent/MA23621A1/fr unknown
- 1995-07-19 TN TNTNSN95083A patent/TNSN95083A1/fr unknown
- 1995-07-19 PE PE1995274242A patent/PE35896A1/es not_active Application Discontinuation
- 1995-07-19 KR KR1019950021178A patent/KR960004343A/ko not_active Withdrawn
- 1995-07-19 RU RU95113086/04A patent/RU95113086A/ru unknown
- 1995-07-19 ZA ZA956015A patent/ZA956015B/xx unknown
- 1995-07-19 NO NO952866A patent/NO304488B1/no not_active IP Right Cessation
- 1995-07-19 CZ CZ951873A patent/CZ187395A3/cs unknown
- 1995-07-19 YU YU49195A patent/YU49195A/sh unknown
- 1995-07-19 HU HU9502167A patent/HUT74003A/hu unknown
- 1995-07-19 CN CN95108995A patent/CN1121919A/zh active Pending
- 1995-07-19 SK SK916-95A patent/SK91695A3/sk unknown
- 1995-07-20 SV SV1995000042A patent/SV1995000042A/es unknown

Also Published As

Publication number	Publication date
SK91695A3 (en)	1996-02-07
PL309685A1 (en)	1996-01-22
CA2154026A1 (en)	1996-01-21
SV1995000042A (es)	1996-03-28
FI953476A7 (fi)	1996-01-21
HU9502167D0 (en)	1995-09-28
TNSN95083A1 (fr)	1996-02-06
CZ187395A3 (en)	1996-02-14
ZA956015B (en)	1996-02-22
BG99791A (en)	1996-04-30
FI953476L (fi)	1996-01-21
EP0693491A1 (de)	1996-01-24
JPH0853443A (ja)	1996-02-27
RU95113086A (ru)	1997-06-27
EE9500044A (et)	1996-02-15
PE35896A1 (es)	1996-10-14
HRP950391A2 (en)	1997-06-30
HUT74003A (en)	1996-10-28
DE4425613A1 (de)	1996-01-25
CN1121919A (zh)	1996-05-08
IL114622A0 (en)	1995-11-27
FI953476A0 (fi)	1995-07-18
IL114622A (en)	1999-07-14
MA23621A1 (fr)	1996-04-01
AU695661B2 (en)	1998-08-20
NZ272596A (en)	1997-03-24
US5698574A (en)	1997-12-16
NO952866L (no)	1996-01-22
AU2498895A (en)	1996-02-01
KR960004343A (ko)	1996-02-23
RO115161B1 (ro)	1999-11-30
NO952866D0 (no)	1995-07-19
YU49195A (sh)	1998-12-23
CO4410193A1 (es)	1997-01-09

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ID26340A (id)	2000-12-14	Kapsul ganda dengan penggunaan bahan-bahan aktif dalam berbagai macam pengobatan
NO308287B1 (no)	2000-08-28	Substituerte 4-fenyl-6-amino-nikotinsyrederivater, legemidler inneholdende disse samt deres anvendelse
NO890792D0 (no)	1989-02-24	Termoplastiske formmasser, samt anvendelse av slike.
NO941903D0 (no)	1994-05-20	Fortilsetning for drövtyggere samt forpellet inneholdende samme
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IL127518A0 (en)	1999-10-28	Substituted heterocyclic benzocycloalkenes and the use thereof as substances having an analgesic effect
DK51589A (da)	1989-08-06	5-substituerede ornithinderivater samt anvendelse heraf
DE68919154D1 (de)	1994-12-08	Benzodiazepinverbindungen und ihre Verwendung als Arzneimittel.
NO960529D0 (no)	1996-02-09	Substituerte benzensulfonylureaer og -tioureaer, fremgangsmåte for fremstilling av disse, og deres anvendelse for fremstilling av farmasöytiske preparater samt farmasöytiske preparater inneholdende forbindelsene
NO904016D0 (no)	1990-09-14	Paafoerings-hjelpemiddel samt anvendelse av dette.
NO305795B1 (no)	1999-07-26	Substituerte benzensulfonylurinstoffer og -tiourinstoffer, og anvendelse i farmas°ytiske preparater pÕ basis av disse forbindelsene samt legemidler inneholdende forbindelsene
AU6119398A (en)	1998-09-22	Phenylpropenone compounds and medicines containing the same
NO306212B1 (no)	1999-10-04	Oligosakkarid selektivt for 1,3-L-fucosyltransferase samt anvendelse av samme
NO308528B1 (no)	2000-09-25	Substituerte 1-naftoylguanidiner, deres anvendelse for fremstilling av medikamenter samt helbredende middel inneholdende forbindelsene
NO970140D0 (no)	1997-01-13	Technetium-sulfonamidkomplekser, deres anvendelse, farmasöytiske midler inneholdende disse, samt fremgangsmåte for fremstilling av kompleksene og midlene

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