NO304117B1 - Konjugat av pneumokokkpolysakkarid og immunogent protein, fremgangsmÕte for fremstilling av konjugatet, samt vaksine som inneholder konjugatet - Google Patents

Konjugat av pneumokokkpolysakkarid og immunogent protein, fremgangsmÕte for fremstilling av konjugatet, samt vaksine som inneholder konjugatet Download PDF

Info

Publication number: NO304117B1
Authority: NO; Norway
Prior art keywords: approx; polysaccharide; conjugate; solution; hours
Prior art date: 1991-01-28

Application number

NO920350A

Other languages

English (en)

Norwegian (no)

Other versions

NO920350D0 (no

NO920350L (no

Inventor

Peter J Kniskern

Charlotte C Ip

Arpi Hagopian

John P Hennessey Jr

William J Miller

Dennis J Kubek

Pamela D Burke

Stephen Marburg

Richard L Tolman

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-01-28

Filing date

1992-01-27

Publication date

1998-10-26

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27094961&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO304117(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1992-01-27 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1992-01-27 Publication of NO920350D0 publication Critical patent/NO920350D0/no

1992-07-29 Publication of NO920350L publication Critical patent/NO920350L/no

1998-10-26 Publication of NO304117B1 publication Critical patent/NO304117B1/no

Links

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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Mycology (AREA)
Microbiology (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Steroid Compounds (AREA)

NO920350A 1991-01-28 1992-01-27 Konjugat av pneumokokkpolysakkarid og immunogent protein, fremgangsmÕte for fremstilling av konjugatet, samt vaksine som inneholder konjugatet NO304117B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US64657091A	1991-01-28	1991-01-28
US80794291A	1991-12-19	1991-12-19

Publications (3)

Publication Number	Publication Date
NO920350D0 NO920350D0 (no)	1992-01-27
NO920350L NO920350L (no)	1992-07-29
NO304117B1 true NO304117B1 (no)	1998-10-26

Family

ID=27094961

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO920350A NO304117B1 (no)	1991-01-28	1992-01-27	Konjugat av pneumokokkpolysakkarid og immunogent protein, fremgangsmÕte for fremstilling av konjugatet, samt vaksine som inneholder konjugatet

Country Status (23)

Country	Link
US (1)	US5623057A (es)
EP (1)	EP0497525B2 (es)
JP (1)	JPH0794472B2 (es)
KR (1)	KR100243958B1 (es)
CN (1)	CN1080124C (es)
AT (1)	ATE169825T1 (es)
AU (1)	AU651656B2 (es)
CA (1)	CA2059692C (es)
CZ (1)	CZ283284B6 (es)
DE (1)	DE69226668T3 (es)
DK (1)	DK0497525T4 (es)
ES (1)	ES2121820T5 (es)
FI (1)	FI107370B (es)
HU (1)	HU216101B (es)
IE (1)	IE920244A1 (es)
IL (5)	IL119961A (es)
LV (1)	LV12309B (es)
MX (1)	MX9200328A (es)
NO (1)	NO304117B1 (es)
NZ (1)	NZ241367A (es)
SI (1)	SI9210081B (es)
SK (1)	SK280659B6 (es)
YU (1)	YU49068B (es)

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US5445817A (en) *	1992-08-21	1995-08-29	The United States Of America As Represented By The Department Of Health And Human Services	Pertussis toxin used as a carrier protein with non-charged saccharides in conjugate vaccines
US5439808A (en) *	1993-07-23	1995-08-08	North American Vaccine, Inc.	Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
US5565204A (en) *	1994-08-24	1996-10-15	American Cyanamid Company	Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections
US5681570A (en) *	1995-01-12	1997-10-28	Connaught Laboratories Limited	Immunogenic conjugate molecules
US5747287A (en) *	1995-04-28	1998-05-05	North American Vaccine, Inc.	Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
US5866132A (en) *	1995-06-07	1999-02-02	Alberta Research Council	Immunogenic oligosaccharide compositions
KR19990007777A (ko) *	1995-06-07	1999-01-25	듀크두플레시스	면역성 및 면역자극성 올리고당 조성물 및 이를 제조하고 이용하는 방법
US5695768A (en)	1995-06-07	1997-12-09	Alberta Research Council	Immunostimulating activity of Streptococcus pneumoniae serotype 8 oligosaccharides
US6410025B1 (en)	1996-02-14	2002-06-25	Merck & Co., Inc.	Polysaccharide precipitation process
SE9601158D0 (sv) *	1996-03-26	1996-03-26	Stefan Svenson	Method of producing immunogenic products and vaccines
US6207157B1 (en)	1996-04-23	2001-03-27	The United States Of America As Represented By The Department Of Health And Human Services	Conjugate vaccine for nontypeable Haemophilus influenzae
DE69708318T3 (de)	1996-08-27	2006-11-16	Novartis Vaccines and Diagnostics, Inc., Emeryville	Neisseria meningitidis serogruppe b glykokonjugate und verfahren zu deren verwendung
FR2763244B1 (fr) *	1997-05-14	2003-08-01	Pasteur Merieux Serums Vacc	Composition vaccinale multivalente a porteur mixte
EP0998557A2 (en)	1997-07-21	2000-05-10	North American Vaccine, Inc.	Modified immunogenic pneumolysin, compositions and their use as vaccines
US6224880B1 (en)	1997-09-24	2001-05-01	Merck & Co., Inc.	Immunization against Streptococcus pneumoniae using conjugated and unconjugated pneumoccocal polysaccharide vaccines
US6756361B1 (en) *	1997-10-14	2004-06-29	Nabi	Enterococcus antigens and vaccines
GB9727262D0 (en) *	1997-12-24	1998-02-25	Smithkline Beecham Biolog	Vaccine
IL137809A0 (en) *	1998-02-12	2001-10-31	American Cyanamid Co	Pneumococcal and meningococcal vaccines formulated with interleukin-12
US7018637B2 (en) *	1998-02-23	2006-03-28	Aventis Pasteur, Inc	Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
WO1999055715A2 (en) *	1998-04-28	1999-11-04	Galenica Pharmaceuticals, Inc.	Polysaccharide-antigen conjugates
GB9816337D0 (en) *	1998-07-27	1998-09-23	Cortecs Uk Ltd	Proteins
US9134303B1 (en)	1998-08-25	2015-09-15	Alere Scarborough, Inc.	ICT immunoassay for Legionella pneumophila serogroup 1 antigen employing affinity purified antibodies thereto
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- 1992-01-27 DK DK92300655.5T patent/DK0497525T4/da active
- 1992-01-27 FI FI920353A patent/FI107370B/fi active
- 1992-01-27 NO NO920350A patent/NO304117B1/no not_active IP Right Cessation
- 1992-01-27 ES ES92300655T patent/ES2121820T5/es not_active Expired - Lifetime
- 1992-01-27 EP EP92300655A patent/EP0497525B2/en not_active Expired - Lifetime
- 1992-01-27 CN CN92100700A patent/CN1080124C/zh not_active Expired - Lifetime
- 1992-01-27 IE IE024492A patent/IE920244A1/en unknown
- 1992-01-28 JP JP4012941A patent/JPH0794472B2/ja not_active Expired - Lifetime
1994
- 1994-05-20 US US08/246,394 patent/US5623057A/en not_active Expired - Lifetime
1997
- 1997-01-03 IL IL11996197A patent/IL119961A0/xx unknown
- 1997-01-03 IL IL11996297A patent/IL119962A0/xx unknown
1999
- 1999-04-26 LV LVP-99-69A patent/LV12309B/en unknown

Also Published As

Publication number	Publication date
HU9200252D0 (en)	1992-04-28
ES2121820T5 (es)	2010-05-28
SI9210081A (en)	1996-02-29
EP0497525B2 (en)	2010-03-03
YU49068B (sh)	2003-08-29
NO920350D0 (no)	1992-01-27
US5623057A (en)	1997-04-22
EP0497525A2 (en)	1992-08-05
FI920353A0 (fi)	1992-01-27
IE920244A1 (en)	1992-07-29
IL119962A0 (en)	1997-04-15
IL119961A0 (en)	1997-04-15
LV12309B (en)	1999-11-20
HUT69968A (en)	1995-09-28
DE69226668T2 (de)	1999-04-22
LV12309A (lv)	1999-07-20
ES2121820T3 (es)	1998-12-16
EP0497525A3 (en)	1993-03-10
ATE169825T1 (de)	1998-09-15
MX9200328A (es)	1992-09-01
NZ241367A (en)	1994-04-27
SK280659B6 (sk)	2000-05-16
KR100243958B1 (ko)	2000-02-01
AU651656B2 (en)	1994-07-28
IL119962A (en)	2000-01-31
EP0497525B1 (en)	1998-08-19
HU216101B (hu)	1999-04-28
DE69226668D1 (de)	1998-09-24
YU8192A (sh)	1994-12-28
CN1080124C (zh)	2002-03-06
NO920350L (no)	1992-07-29
JPH0794472B2 (ja)	1995-10-11
DK0497525T3 (da)	1998-10-26
CA2059692A1 (en)	1992-07-29
DE69226668T3 (de)	2010-12-16
KR920014829A (ko)	1992-08-25
DK0497525T4 (da)	2010-07-05
FI107370B (fi)	2001-07-31
IL100716A0 (en)	1992-09-06
CA2059692C (en)	2004-11-16
CZ283284B6 (cs)	1998-02-18
SI9210081B (en)	2001-12-31
IL119961A (en)	2000-01-31
IL100716A (en)	1999-12-22
AU1046792A (en)	1992-07-30
CS19992A3 (en)	1992-10-14
FI920353L (fi)	1992-07-29
CN1064217A (zh)	1992-09-09
JPH0565300A (ja)	1993-03-19

Publication	Publication Date	Title
NO304117B1 (no)	1998-10-26	Konjugat av pneumokokkpolysakkarid og immunogent protein, fremgangsmÕte for fremstilling av konjugatet, samt vaksine som inneholder konjugatet
EP0497524B1 (en)	1998-07-15	Polysaccharide antigens from streptococcus pneumoniae
EP0161188B1 (en)	1991-04-03	Covalently-modified bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency
US4830852A (en)	1989-05-16	Covalently-modified neutral bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins and methods of preparing such polysaccharides and conjugates
US4882317A (en)	1989-11-21	Covalently-modified bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers and methods of preparing such polysaccharides and conjugataes and of confirming covalency
AU2025256067A1 (en)	2025-11-13	Improvements in immunogenic conjugates
HK40121270A (en)	2025-09-12	Improvements in immunogenic conjugates
HK40050310A (en)	2021-12-24	Improvements in immunogenic conjugates
HK40050310B (en)	2025-02-28	Improvements in immunogenic conjugates

Legal Events

Date	Code	Title	Description
2012-02-20	MK1K	Patent expired