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NO20090289L - Inhibitorer av akt (proteinkinase B) - Google Patents

Inhibitorer av akt (proteinkinase B)

Info

Publication number
NO20090289L
NO20090289L NO20090289A NO20090289A NO20090289L NO 20090289 L NO20090289 L NO 20090289L NO 20090289 A NO20090289 A NO 20090289A NO 20090289 A NO20090289 A NO 20090289A NO 20090289 L NO20090289 L NO 20090289L
Authority
NO
Norway
Prior art keywords
protein kinase
act inhibitors
inhibitors
act
compounds
Prior art date
Application number
NO20090289A
Other languages
English (en)
Inventor
Christopher Randall Schmid
Michael R Myers
Renhua Li
Sajan Joseph
Aktham Aburub
Jenny Pingqi Dai
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO20090289L publication Critical patent/NO20090289L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

4-[5-(2- amino-etansulfonyl)-isoquinolin-7-yl]-fenol eller farmasøytisk akseptabelt salt derav eller et hydrat av forbindelsen eller saltet derav som aktive inhibitorer som er antineoplastiske og/eller antivirale midler så vel som sammensetninger som innbefatter disse forbinderlser og fremgangsmåter for anvendelse av disse forbindelsene
NO20090289A 2006-06-20 2009-01-19 Inhibitorer av akt (proteinkinase B) NO20090289L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80526006P 2006-06-20 2006-06-20
US88576507P 2007-01-19 2007-01-19
PCT/US2007/070945 WO2007149730A2 (en) 2006-06-20 2007-06-12 Inhibitors of akt (protein kinase b)

Publications (1)

Publication Number Publication Date
NO20090289L true NO20090289L (no) 2009-01-19

Family

ID=38834248

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090289A NO20090289L (no) 2006-06-20 2009-01-19 Inhibitorer av akt (proteinkinase B)

Country Status (28)

Country Link
US (1) US7998977B2 (no)
EP (1) EP2035385B1 (no)
JP (1) JP2009541335A (no)
KR (1) KR101067551B1 (no)
AR (1) AR061240A1 (no)
AT (1) ATE455102T1 (no)
AU (1) AU2007261120A1 (no)
BR (1) BRPI0713136A2 (no)
CA (1) CA2652612A1 (no)
CL (1) CL2007001752A1 (no)
DE (1) DE602007004333D1 (no)
DK (1) DK2035385T3 (no)
DO (1) DOP2008000053A (no)
EA (1) EA015712B1 (no)
EC (1) ECSP088992A (no)
ES (1) ES2336630T3 (no)
HR (1) HRP20100147T1 (no)
IL (1) IL195005A0 (no)
MA (1) MA30757B1 (no)
MX (1) MX2008015904A (no)
NO (1) NO20090289L (no)
PE (1) PE20080338A1 (no)
PL (1) PL2035385T3 (no)
PT (1) PT2035385E (no)
SI (1) SI2035385T1 (no)
TN (1) TNSN08529A1 (no)
TW (1) TW200812970A (no)
WO (1) WO2007149730A2 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5856843B2 (ja) 2008-05-27 2016-02-10 アンピオ ファーマシューティカルズ，インコーポレイテッド ジケトピペラジンを用いた医薬組成物
WO2012033792A2 (en) 2010-09-07 2012-03-15 Dmi Acquisition Corp. Treatment of diseases
MX362164B (es) 2011-10-10 2019-01-07 Ampio Pharmaceuticals Inc Tratamiento de enfermedad de articulacion degenerativa.
BR112014007657A2 (pt) 2011-10-10 2017-04-11 Ampio Pharmaceuticals Inc dispositivos médicos implantáveis com tolerância imune aperfeiçoada e métodos para produção e implantação
SG11201400283RA (en) 2011-10-28 2014-03-28 Ampio Pharmaceuticals Inc Treatment of rhinitis
SG10201707619RA (en) 2013-03-15 2017-10-30 Ampio Pharmaceuticals Inc Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
WO2015013579A1 (en) 2013-07-26 2015-01-29 Update Pharma Inc. Compositions to improve the therapeutic benefit of bisantrene
EP3183240A4 (en) 2014-08-18 2018-06-27 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
US10123997B2 (en) * 2015-06-15 2018-11-13 Yong Liao Target for treating hepatitis B virus
HK1246669A1 (zh) 2015-06-22 2018-09-14 Ampio Pharmaceuticals, Inc. 人血清白蛋白低分子量组分在疾病治疗中的应用
WO2017156350A1 (en) 2016-03-09 2017-09-14 K-Gen, Inc. Methods of cancer treatment
WO2022017448A1 (zh) * 2020-07-22 2022-01-27 南京正大天晴制药有限公司 一种二氢吡啶并[2,3-d]嘧啶酮衍生物的盐及晶型
CA3186565A1 (en) * 2020-07-22 2022-01-27 Lei Miao Unit dosage composition of akt inhibitor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL136458A0 (en) 2000-05-30 2001-06-14 Peptor Ltd Protein kinase inhibitors
CA2518180A1 (en) 2003-03-28 2004-11-04 Eli Lilly And Company Isoquinoline-5-sulfonic acid amides as inhibitors of akt (protein kinase b)
GB0317315D0 (en) 2003-07-24 2003-08-27 Astex Technology Ltd Pharmaceutical compounds
US7449477B2 (en) 2003-11-25 2008-11-11 Eli Lilly And Company 7-phenyl-isoquinoline-5-sulfonylamino derivatives as inhibitors of akt (protein kinase B)

Also Published As

Publication number Publication date
US7998977B2 (en) 2011-08-16
DOP2008000053A (es) 2009-01-15
ATE455102T1 (de) 2010-01-15
DE602007004333D1 (de) 2010-03-04
AR061240A1 (es) 2008-08-13
PT2035385E (pt) 2010-03-01
EP2035385B1 (en) 2010-01-13
KR20090015978A (ko) 2009-02-12
AU2007261120A1 (en) 2007-12-27
DK2035385T3 (da) 2010-03-22
MA30757B1 (fr) 2009-10-01
MX2008015904A (es) 2009-01-12
IL195005A0 (en) 2009-08-03
EA015712B1 (ru) 2011-10-31
PL2035385T3 (pl) 2010-06-30
ECSP088992A (es) 2009-01-30
US20090221633A1 (en) 2009-09-03
SI2035385T1 (sl) 2010-05-31
TW200812970A (en) 2008-03-16
WO2007149730A2 (en) 2007-12-27
EP2035385A2 (en) 2009-03-18
ES2336630T3 (es) 2010-04-14
TNSN08529A1 (en) 2010-04-14
HRP20100147T1 (hr) 2010-04-30
JP2009541335A (ja) 2009-11-26
PE20080338A1 (es) 2008-04-25
BRPI0713136A2 (pt) 2012-04-17
KR101067551B1 (ko) 2011-09-27
EA200970041A1 (ru) 2009-06-30
WO2007149730A3 (en) 2008-04-24
CL2007001752A1 (es) 2008-01-18
CA2652612A1 (en) 2007-12-27

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