NO20085158L - Farmasoytiske blandinger av ropinirol samt deres anvendelse - Google Patents
Farmasoytiske blandinger av ropinirol samt deres anvendelseInfo
- Publication number
- NO20085158L NO20085158L NO20085158A NO20085158A NO20085158L NO 20085158 L NO20085158 L NO 20085158L NO 20085158 A NO20085158 A NO 20085158A NO 20085158 A NO20085158 A NO 20085158A NO 20085158 L NO20085158 L NO 20085158L
- Authority
- NO
- Norway
- Prior art keywords
- agents
- compositions
- ropinirole
- hydroalcoholic
- present
- Prior art date
Links
- UHSKFQJFRQCDBE-UHFFFAOYSA-N ropinirole Chemical group CCCN(CCC)CCC1=CC=CC2=C1CC(=O)N2 UHSKFQJFRQCDBE-UHFFFAOYSA-N 0.000 title abstract 2
- 229960001879 ropinirole Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 239000003963 antioxidant agent Substances 0.000 abstract 2
- 239000006172 buffering agent Substances 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 239000006184 cosolvent Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003349 gelling agent Substances 0.000 abstract 1
- QNLOWBMKUIXCOW-UHFFFAOYSA-N indol-2-one Chemical compound C1=CC=CC2=NC(=O)C=C21 QNLOWBMKUIXCOW-UHFFFAOYSA-N 0.000 abstract 1
- FGFUBBNNYLNVLJ-UHFFFAOYSA-N indolone Natural products C1=CC=C2C(=O)C=NC2=C1 FGFUBBNNYLNVLJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003961 penetration enhancing agent Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- -1 ropinirole) Chemical compound 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychology (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Foreliggende oppfinnelse omfatter preparater for levering av et farmasøytisk medikament av et indolon (for eksempel ropinirol), eller et farmasøytisk akseptabelt salt derav. Preparatet kan for eksempel være en gel egnet for transdermal anvendelse. Preparatene ifølge foreliggende oppfinnelse omfatter typisk en hydro- alkoholisk konstituent, en eller flere antioksidanter og ett eller flere bufringsmidler, hvor pH i gelen vanligvis er mellom ca. pH 7 og ca. pH 9. Preparatene kan omfatte ytterligere komponenter; for eksempel kan den hydroalkoholiske konstituenten videre omfatte ytterligere løsningsmiddel/midler, antioksidant(er), medløsningsmiddel/midler, penetreringsforbedrende middel/midler, bufringsmiddel/midler og/eller geldannende middel/midler. Preparatene kan anvendes for behandling av en rekke nevrologiske lidelser.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81725906P | 2006-06-29 | 2006-06-29 | |
| PCT/US2007/014821 WO2008005240A2 (en) | 2006-06-29 | 2007-06-26 | Ropinirole-containing pharmaceutical compositions in the form of a gel, uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20085158L true NO20085158L (no) | 2009-01-15 |
Family
ID=38895093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20085158A NO20085158L (no) | 2006-06-29 | 2008-12-11 | Farmasoytiske blandinger av ropinirol samt deres anvendelse |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20080004329A1 (no) |
| EP (1) | EP2032125A2 (no) |
| JP (1) | JP2009542657A (no) |
| KR (1) | KR20090031598A (no) |
| CN (1) | CN101478952A (no) |
| AR (1) | AR063201A1 (no) |
| AU (1) | AU2007269896A1 (no) |
| BR (1) | BRPI0713801A2 (no) |
| CA (1) | CA2654383A1 (no) |
| IL (1) | IL195161A0 (no) |
| MX (1) | MX2008015083A (no) |
| NO (1) | NO20085158L (no) |
| NZ (1) | NZ572481A (no) |
| PE (1) | PE20080374A1 (no) |
| TW (1) | TW200815045A (no) |
| UY (1) | UY30442A1 (no) |
| WO (1) | WO2008005240A2 (no) |
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|---|---|---|---|---|
| US11400065B2 (en) | 2019-03-01 | 2022-08-02 | Flamel Ireland Limited | Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state |
| US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11839597B2 (en) | 2016-07-22 | 2023-12-12 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11986451B1 (en) | 2016-07-22 | 2024-05-21 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12186296B1 (en) | 2016-07-22 | 2025-01-07 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12295926B1 (en) | 2022-02-07 | 2025-05-13 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12478604B1 (en) | 2016-07-22 | 2025-11-25 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
Families Citing this family (39)
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| US20070212397A1 (en) * | 2005-09-15 | 2007-09-13 | Roth Daniel B | Pharmaceutical delivery device and method for providing ocular treatment |
| US9050293B2 (en) | 2008-07-16 | 2015-06-09 | Juventio, Llc | Small molecule solubilization system |
| US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
| SG2014007389A (en) | 2009-01-29 | 2014-04-28 | Forsight Vision4 Inc | Posterior segment drug delivery |
| JP5933974B2 (ja) * | 2009-04-24 | 2016-06-15 | 久光製薬株式会社 | 貼付剤入り包装袋、及び貼付剤の保存方法 |
| SMT201700583T1 (it) * | 2009-09-28 | 2018-01-11 | Intarcia Therapeutics Inc | Instaurazione e/o terminazione rapida di erogazione di farmaci in modo sostanzialmente stazionario |
| WO2013022801A1 (en) | 2011-08-05 | 2013-02-14 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device |
| KR20120137373A (ko) | 2010-04-30 | 2012-12-20 | 테이코쿠 팔마 유에스에이, 인코포레이티드 | 프로필아미노인단 경피 조성물 |
| HRP20211909T1 (hr) | 2010-08-05 | 2022-03-18 | Forsight Vision4, Inc. | Uređaj za liječenja oka |
| CN105435338B (zh) | 2010-08-05 | 2019-03-26 | 弗赛特影像4股份有限公司 | 用于药物输送的注入器装置和方法 |
| WO2012019139A1 (en) | 2010-08-05 | 2012-02-09 | Forsight Vision4, Inc. | Combined drug delivery methods and apparatus |
| CA2818612C (en) | 2010-11-19 | 2020-12-29 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
| KR101853082B1 (ko) | 2011-03-24 | 2018-04-27 | 테이코쿠 팔마 유에스에이, 인코포레이티드 | 활성제층 및 활성제 변환층을 포함하는 경피 조성물 |
| WO2012165254A1 (ja) * | 2011-05-31 | 2012-12-06 | 久光製薬株式会社 | ロピニロール含有貼付剤及びその包装体 |
| US10398592B2 (en) | 2011-06-28 | 2019-09-03 | Forsight Vision4, Inc. | Diagnostic methods and apparatus |
| DK2755600T3 (da) | 2011-09-16 | 2021-05-03 | Forsight Vision4 Inc | Fluidudvekslingsindretning |
| WO2013070526A1 (en) | 2011-11-09 | 2013-05-16 | Teikoku Pharma Usa, Inc. | Methods for the treatment of skin neoplasms |
| WO2013116061A1 (en) | 2012-02-03 | 2013-08-08 | Forsight Vision4, Inc. | Insertion and removal methods and apparatus for therapeutic devices |
| AU2013289403B2 (en) | 2012-07-12 | 2017-05-11 | Ferring B.V. | Diclofenac formulations |
| US10918607B2 (en) | 2012-11-02 | 2021-02-16 | Teikoku Pharma Usa, Inc. | Propynylaminoindan transdermal compositions |
| WO2014084311A1 (ja) * | 2012-11-30 | 2014-06-05 | 帝國製薬株式会社 | ロピニロール含有貼付剤 |
| CA2905496A1 (en) | 2013-03-14 | 2014-09-25 | Forsight Vision4, Inc. | Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant |
| US9526654B2 (en) | 2013-03-28 | 2016-12-27 | Forsight Vision4, Inc. | Ophthalmic implant for delivering therapeutic substances |
| PL2981269T3 (pl) | 2013-04-04 | 2024-02-05 | Boehringer Ingelheim Vetmedica Gmbh | Leczenie zaburzeń metabolicznych u zwierząt koniowatych |
| US9463889B2 (en) * | 2013-10-25 | 2016-10-11 | Medtronic, Inc. | Prefilled reservoir apparatus for ambulatory infusion device |
| KR102416726B1 (ko) | 2014-07-15 | 2022-07-05 | 포사이트 비젼4, 인크. | 안구 이식물 전달 디바이스 및 방법 |
| SG11201700943TA (en) | 2014-08-08 | 2017-03-30 | Forsight Vision4 Inc | Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof |
| EP3197429B1 (en) * | 2014-09-25 | 2024-05-22 | Boehringer Ingelheim Vetmedica GmbH | Combination treatment of sglt2 inhibitors and dopamine agonists for preventing metabolic disorders in equine animals |
| CN114587774B (zh) | 2014-11-10 | 2024-07-19 | 弗赛特影像4股份有限公司 | 治疗眼睛的系统 |
| WO2016167345A1 (ja) * | 2015-04-15 | 2016-10-20 | 久光製薬株式会社 | ロピニロール含有貼付剤 |
| WO2017087902A1 (en) | 2015-11-20 | 2017-05-26 | Forsight Vision4, Inc. | Porous structures for extended release drug delivery devices |
| IL260290B2 (en) | 2015-12-30 | 2023-11-01 | Corium Inc | Systems and methods for long-term percutaneous administration |
| WO2017176886A1 (en) | 2016-04-05 | 2017-10-12 | Forsight Vision4, Inc. | Implantable ocular drug delivery devices |
| AU2017281789B2 (en) | 2016-06-23 | 2023-04-13 | Corium, LLC. | Adhesive matrix with hydrophilic and hydrophobic domains and a therapeutic agent |
| CN116270551A (zh) * | 2016-07-27 | 2023-06-23 | 考里安有限责任公司 | 通过盐至中性药物原位转化的组合物、透皮贴剂及应用 |
| WO2019103906A1 (en) | 2017-11-21 | 2019-05-31 | Forsight Vision4, Inc. | Fluid exchange apparatus for expandable port delivery system and methods of use |
| KR102212722B1 (ko) * | 2019-12-23 | 2021-02-08 | 환인제약 주식회사 | 로피니롤을 포함하는 마이크로스피어 및 이를 함유하는 주사제 조성물 |
| USD1033637S1 (en) | 2022-01-24 | 2024-07-02 | Forsight Vision4, Inc. | Fluid exchange device |
| CN116763842B (zh) * | 2023-07-11 | 2025-03-04 | 海南职业技术学院 | 一种胆木浸膏凝胶剂及其制备工艺 |
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-
2007
- 2007-06-14 TW TW096121617A patent/TW200815045A/zh unknown
- 2007-06-26 NZ NZ572481A patent/NZ572481A/en unknown
- 2007-06-26 PE PE2007000821A patent/PE20080374A1/es not_active Application Discontinuation
- 2007-06-26 AU AU2007269896A patent/AU2007269896A1/en not_active Abandoned
- 2007-06-26 JP JP2009518225A patent/JP2009542657A/ja not_active Withdrawn
- 2007-06-26 WO PCT/US2007/014821 patent/WO2008005240A2/en not_active Ceased
- 2007-06-26 CN CNA2007800229856A patent/CN101478952A/zh active Pending
- 2007-06-26 EP EP07809906A patent/EP2032125A2/en not_active Withdrawn
- 2007-06-26 BR BRPI0713801-6A patent/BRPI0713801A2/pt not_active IP Right Cessation
- 2007-06-26 CA CA002654383A patent/CA2654383A1/en not_active Abandoned
- 2007-06-26 KR KR1020097001878A patent/KR20090031598A/ko not_active Withdrawn
- 2007-06-26 MX MX2008015083A patent/MX2008015083A/es not_active Application Discontinuation
- 2007-06-26 US US11/823,028 patent/US20080004329A1/en not_active Abandoned
- 2007-06-27 UY UY30442A patent/UY30442A1/es not_active Application Discontinuation
- 2007-06-28 AR ARP070102901A patent/AR063201A1/es unknown
-
2008
- 2008-11-06 IL IL195161A patent/IL195161A0/en unknown
- 2008-12-11 NO NO20085158A patent/NO20085158L/no not_active Application Discontinuation
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| US12167992B2 (en) | 2019-03-01 | 2024-12-17 | Flamel Ireland Limited | Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state |
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| US11400065B2 (en) | 2019-03-01 | 2022-08-02 | Flamel Ireland Limited | Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state |
| US12303478B2 (en) | 2019-03-01 | 2025-05-20 | Flamel Ireland Limited | Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state |
| US12295926B1 (en) | 2022-02-07 | 2025-05-13 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008005240A3 (en) | 2008-05-08 |
| JP2009542657A (ja) | 2009-12-03 |
| MX2008015083A (es) | 2008-12-10 |
| AR063201A1 (es) | 2009-01-14 |
| EP2032125A2 (en) | 2009-03-11 |
| TW200815045A (en) | 2008-04-01 |
| PE20080374A1 (es) | 2008-06-11 |
| CA2654383A1 (en) | 2008-01-10 |
| NZ572481A (en) | 2011-03-31 |
| WO2008005240A2 (en) | 2008-01-10 |
| KR20090031598A (ko) | 2009-03-26 |
| US20080004329A1 (en) | 2008-01-03 |
| BRPI0713801A2 (pt) | 2012-11-06 |
| UY30442A1 (es) | 2008-01-31 |
| CN101478952A (zh) | 2009-07-08 |
| AU2007269896A1 (en) | 2008-01-10 |
| IL195161A0 (en) | 2009-08-03 |
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