NO20084457L - Tiazolidinderivater som P13 kinaseinhibitorer - Google Patents

Tiazolidinderivater som P13 kinaseinhibitorer

Info

Publication number: NO20084457L
Authority: NO; Norway
Prior art keywords: kinase inhibitors; thiazolidine derivatives; thiazolidine; derivatives; kinase
Prior art date: 2006-04-11

Application number

NO20084457A

Other languages

English (en)

Inventor

Nicholas D Adams

Steven David Knight

Michael Gerard Darcy

Stanley J Schmidt

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-04-11

Filing date

2008-10-22

Publication date

2009-01-07

2008-10-22 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

2009-01-07 Publication of NO20084457L publication Critical patent/NO20084457L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Oncology (AREA)
Neurology (AREA)
Pulmonology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Communicable Diseases (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Hospice & Palliative Care (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Diabetes (AREA)
Gynecology & Obstetrics (AREA)
Psychiatry (AREA)
Psychology (AREA)
Dermatology (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Pregnancy & Childbirth (AREA)

NO20084457A 2006-04-11 2008-10-22 Tiazolidinderivater som P13 kinaseinhibitorer NO20084457L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US79113406P	2006-04-11	2006-04-11
PCT/US2007/066359 WO2007136940A2 (en)	2006-04-11	2007-04-11	Thiazolidinedione derivatives as pi3 kinase inhibitors

Publications (1)

Publication Number	Publication Date
NO20084457L true NO20084457L (no)	2009-01-07

Family

ID=38723938

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20084457A NO20084457L (no)	2006-04-11	2008-10-22	Tiazolidinderivater som P13 kinaseinhibitorer

Country Status (19)

Country	Link
US (1)	US20090306074A1 (no)
EP (1)	EP2004189A2 (no)
JP (1)	JP2009533467A (no)
KR (1)	KR20080108611A (no)
CN (1)	CN101466377A (no)
AR (1)	AR060391A1 (no)
AU (1)	AU2007253956A1 (no)
BR (1)	BRPI0710004A2 (no)
CA (1)	CA2649224A1 (no)
CL (1)	CL2007000995A1 (no)
CR (1)	CR10354A (no)
EA (1)	EA200870426A1 (no)
IL (1)	IL194575A0 (no)
MA (1)	MA30395B1 (no)
MX (1)	MX2008013174A (no)
NO (1)	NO20084457L (no)
PE (1)	PE20080038A1 (no)
TW (1)	TW200815429A (no)
WO (1)	WO2007136940A2 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20080255115A1 (en) *	2007-04-11	2008-10-16	Michael Gerard Darcy	Thiazolidinedione derivatives as pi3 kinase inhibitors
PE20090717A1 (es) *	2007-05-18	2009-07-18	Smithkline Beecham Corp	Derivados de quinolina como inhibidores de la pi3 quinasa
GB0801416D0 (en) *	2008-01-25	2008-03-05	Piramed Ltd	Pharmaceutical compounds
WO2011038380A2 (en)	2009-09-28	2011-03-31	Glaxosmithkline Llc	Combination
RU2458688C1 (ru) *	2011-06-23	2012-08-20	Государственное образовательное учреждение высшего профессионального образования "Курский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации	Способ коррекции нарушений структурно-функциональных свойств эритроцитов и иммунного статуса у больных с острым панкреатитом
SG11201406032TA (en) *	2012-03-26	2014-11-27	Nippon Chemiphar Co	Prophylactic or therapeutic agent for giant cell tumors occuring in bone and soft tissue or for chondrosarcoma
JP6378918B2 (ja) *	2013-04-03	2018-08-22	株式会社ヤクルト本社	チアゾリジン誘導体又はその塩を有効成分とするＰｉｍ阻害剤
JP6023630B2 (ja) *	2013-04-03	2016-11-09	株式会社ヤクルト本社	チアゾロン誘導体
US10653667B2 (en)	2013-09-25	2020-05-19	Nippon Chemiphar Co., Ltd	Drug for preventing, treating or preventing metastasis of giant cell tumor that occurs in bone or soft parts, chondrosarcoma, or osteosarcoma, local injection for arterial embolization, and artificial bone
WO2019157516A1 (en)	2018-02-12	2019-08-15	resTORbio, Inc.	Combination therapies
LT3813946T (lt)	2018-06-15	2024-07-10	Janssen Pharmaceutica Nv	Rapamicino analogai ir jų panaudojimas
CN115209897A (zh)	2019-12-05	2022-10-18	安纳库利亚治疗公司	雷帕霉素类似物及其用途

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5965589A (en) *	1994-08-10	1999-10-12	Takeda Chemical Industries, Ltd.	Thiazolidinedione derivatives, their production and use
US5925656A (en) *	1995-04-10	1999-07-20	Dr. Reddy's Research Foundation	Compounds having antidiabetic, hypolipidemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US6452014B1 (en) *	2000-12-22	2002-09-17	Geron Corporation	Telomerase inhibitors and methods of their use
US7153875B2 (en) *	2001-03-07	2006-12-26	Incyte San Diego	Heterocyclic derivatives for the treatment of cancer and other proliferative diseases
EP1377976A2 (de) *	2001-03-28	2004-01-07	Bayer Chemicals AG	Optischer datenträger enthaltend in der informationsschicht einen merocyaninfarbstoff als lichtabsorbierende verbindung
US20050019825A9 (en) *	2002-03-15	2005-01-27	Qing Dong	Common ligand mimics: pseudothiohydantoins
AU2003291613B2 (en) *	2002-04-30	2007-09-27	Merck & Co., Inc.	Aryl-link-aryl substituted thiazolidine-dione and oxazolidine-dione as sodium channel blockers
BR0312752A (pt) *	2002-07-10	2005-04-26	Applied Research Systems	Derivados de benzeno fundido de azolidinona-vinil
US20040092561A1 (en) *	2002-11-07	2004-05-13	Thomas Ruckle	Azolidinone-vinyl fused -benzene derivatives
AU2003255529B2 (en) *	2002-07-10	2008-11-20	Laboratoires Serono Sa	Use of compounds for increasing spermatozoa motility
AU2003291024A1 (en) *	2002-11-13	2004-06-03	Rigel Pharmaceuticals, Inc.	Rhodanine derivatives and pharmaceutical compositions containing them
US20060106077A1 (en) *	2003-07-18	2006-05-18	Pintex Pharmaceuticals, Inc.	Pin1-Modulating compounds and methods of use thereof
EP1648452B1 (en) *	2003-07-28	2009-07-22	Merck Serono SA	2-imino-4-(thio)oxo-5-polycyclovinylazolines for use as pi3 kinase inhibitors
US20050042213A1 (en) *	2003-08-14	2005-02-24	Insight Biopharmaceuticals Ltd.	Methods and pharmaceutical compositions for modulating heparanase activation and uses thereof
ATE420086T1 (de) *	2004-07-01	2009-01-15	Hoffmann La Roche	Chinolinthiazolinone mit cdk-1 antiproliferativer wirkung
US7253285B2 (en) *	2004-09-17	2007-08-07	Hoffmann-La Roche Inc.	Thiazolinone 4-monosubstituted quinolines
US20080255115A1 (en) *	2007-04-11	2008-10-16	Michael Gerard Darcy	Thiazolidinedione derivatives as pi3 kinase inhibitors

2007
- 2007-04-09 AR ARP070101487A patent/AR060391A1/es unknown
- 2007-04-09 CL CL200700995A patent/CL2007000995A1/es unknown
- 2007-04-09 TW TW096112219A patent/TW200815429A/zh unknown
- 2007-04-09 PE PE2007000423A patent/PE20080038A1/es not_active Application Discontinuation
- 2007-04-11 JP JP2009505582A patent/JP2009533467A/ja not_active Withdrawn
- 2007-04-11 EA EA200870426A patent/EA200870426A1/ru unknown
- 2007-04-11 US US12/296,708 patent/US20090306074A1/en not_active Abandoned
- 2007-04-11 BR BRPI0710004-3A patent/BRPI0710004A2/pt not_active Application Discontinuation
- 2007-04-11 WO PCT/US2007/066359 patent/WO2007136940A2/en not_active Ceased
- 2007-04-11 MX MX2008013174A patent/MX2008013174A/es not_active Application Discontinuation
- 2007-04-11 AU AU2007253956A patent/AU2007253956A1/en not_active Abandoned
- 2007-04-11 CN CNA2007800218014A patent/CN101466377A/zh active Pending
- 2007-04-11 KR KR1020087027465A patent/KR20080108611A/ko not_active Withdrawn
- 2007-04-11 CA CA002649224A patent/CA2649224A1/en not_active Abandoned
- 2007-04-11 EP EP07811839A patent/EP2004189A2/en not_active Withdrawn
2008
- 2008-10-06 IL IL194575A patent/IL194575A0/en unknown
- 2008-10-07 CR CR10354A patent/CR10354A/es not_active Application Discontinuation
- 2008-10-22 NO NO20084457A patent/NO20084457L/no not_active Application Discontinuation
- 2008-11-03 MA MA31349A patent/MA30395B1/fr unknown

Also Published As

Publication number	Publication date
MX2008013174A (es)	2008-10-21
IL194575A0 (en)	2009-08-03
EP2004189A2 (en)	2008-12-24
CN101466377A (zh)	2009-06-24
EA200870426A1 (ru)	2009-04-28
CR10354A (es)	2008-10-29
WO2007136940A3 (en)	2008-12-04
AR060391A1 (es)	2008-06-11
US20090306074A1 (en)	2009-12-10
JP2009533467A (ja)	2009-09-17
CA2649224A1 (en)	2007-11-29
BRPI0710004A2 (pt)	2011-08-02
CL2007000995A1 (es)	2008-06-27
PE20080038A1 (es)	2008-02-22
KR20080108611A (ko)	2008-12-15
AU2007253956A1 (en)	2007-11-29
TW200815429A (en)	2008-04-01
MA30395B1 (fr)	2009-05-04
WO2007136940A2 (en)	2007-11-29

Publication	Publication Date	Title
NO20084457L (no)	2009-01-07	Tiazolidinderivater som P13 kinaseinhibitorer
DK2021335T3 (da)	2011-09-05	Heterocykliske forbindelser som C-FMS-kinasehæmmere
DK1959951T3 (da)	2010-03-01	Heteroaryl-substituerede piperidinderivater som L-CPT1-inhibitorer
DK2220070T3 (da)	2011-07-04	2-benzylpyridazinonderivater som Met-kinaseinhibitorer
DK1789041T3 (da)	2008-09-08	Aryl-pyridinderivater som 11-beta-HSD1-inhibitorer
DK1926722T3 (da)	2011-12-19	Substituerede benzimidazoler som kinaseinhibitorer
DK2086939T3 (da)	2010-10-11	Pyridiacarboxamid som II-beta-HSDI-inhibitorer
DK1797042T3 (da)	2009-03-02	Indozolonderivater som 11B-HSD1-inhibitorer
DK1846394T3 (da)	2012-01-16	Pyrazolylaminopyridinderivater, der er egnede som kinaseinhibitorer
DK1910333T3 (da)	2013-08-19	Piperidinylsubstituerede isoquinolonderivater som RHO-kinaseinhibitorer
DK1981875T3 (da)	2014-07-14	Substituerede indolylalkylaminoderivater som inhibitorer af histondeacetylase
CY2016045I2 (el)	2017-04-05	Παραγωγα νιτροκατεχολης ως αναστολεις της comt
DK2094263T3 (da)	2013-12-02	2-adamantyl-butyramidderivater som selektive 11 beta-hsd1-inhibitorer
DK2142514T3 (da)	2015-03-23	Thioureaderivater som glutaminylcyclase-inhibitorer
DK1981892T3 (da)	2014-06-23	Thienopyridinderivater som mek-inhibitorer
DK2125748T3 (da)	2011-08-01	Acylaminopyrazol som FGFR inhibitorer
EP2046333A4 (en)	2010-09-15	THIOZOLIDINEDIONE DERIVATIVES AS INHIBITORS OF P13-KINASE
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