[go: up one dir, main page]

NO20082992L - Ostrogenmodulatorer - Google Patents

Ostrogenmodulatorer

Info

Publication number
NO20082992L
NO20082992L NO20082992A NO20082992A NO20082992L NO 20082992 L NO20082992 L NO 20082992L NO 20082992 A NO20082992 A NO 20082992A NO 20082992 A NO20082992 A NO 20082992A NO 20082992 L NO20082992 L NO 20082992L
Authority
NO
Norway
Prior art keywords
ostrogenmodulatorer
isoxazoles
present application
application relates
new class
Prior art date
Application number
NO20082992A
Other languages
English (en)
Inventor
Stephen Alan Fakhoury
Larry Don Bratton
Simon Bailey
Stephen Douglas Barrett
Sandra Marie Jennings
Lorna Helen Mitchell
Raj Kumar Raheja
Veerabahu Shanmugasundaram
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO20082992L publication Critical patent/NO20082992L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing alicyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Foreliggende søknad angår en ny klasse isoksazoler og deres anvendelse som østrogenmodulatorer.
NO20082992A 2005-12-22 2008-07-02 Ostrogenmodulatorer NO20082992L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75278005P 2005-12-22 2005-12-22
US80523306P 2006-06-20 2006-06-20
PCT/IB2006/003671 WO2007072164A2 (en) 2005-12-22 2006-12-11 Estrogen modulators

Publications (1)

Publication Number Publication Date
NO20082992L true NO20082992L (no) 2008-09-22

Family

ID=38066616

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082992A NO20082992L (no) 2005-12-22 2008-07-02 Ostrogenmodulatorer

Country Status (17)

Country Link
US (2) US7470715B2 (no)
EP (1) EP1966170A2 (no)
JP (1) JP2009520808A (no)
KR (1) KR20080073346A (no)
AP (1) AP2008004481A0 (no)
AR (1) AR058611A1 (no)
AU (1) AU2006327877A1 (no)
BR (1) BRPI0620215A2 (no)
CA (1) CA2628596A1 (no)
EA (1) EA200801407A1 (no)
EC (1) ECSP088533A (no)
NL (1) NL2000351C2 (no)
NO (1) NO20082992L (no)
PE (1) PE20070815A1 (no)
RS (1) RS20080267A (no)
UY (1) UY30047A1 (no)
WO (1) WO2007072164A2 (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2013001612A (es) * 2010-08-10 2013-07-05 Abbvie Inc Moduladores de trpv3 novedosos.
CN111938907B (zh) * 2020-08-12 2022-07-01 中国人民解放军陆军军医大学第一附属医院 一种鼻部手术后外敷面罩
GB2608397B (en) * 2021-06-29 2025-04-09 Chaitowitz Ilan Gynecomastia treatment

Family Cites Families (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US525666A (en) * 1894-09-04 Axel sarnmark
US9799A (en) * 1853-06-21 Simon ikgeksoll
US171412A (en) * 1875-12-21 Improvement in buck-boards
US256210A (en) * 1882-04-11 Bodolphe t
US207927A (en) * 1878-09-10 Improvement in horse hay-rakes
GB1012182A (en) 1963-04-23 1965-12-08 Ass Portland Cement Improvement in the manufacture of hydraulic cement
JPS63108339A (ja) 1986-10-27 1988-05-13 Fuji Photo Film Co Ltd ハロゲン化銀カラ−感光材料の処理方法
GB2201672A (en) 1986-12-18 1988-09-07 Shell Int Research Diphenyl ether compounds
US4952700A (en) 1988-04-25 1990-08-28 W.R. Grace & Co.-Conn. Preparation of isoxazolines and isoxazoles
US4933464A (en) 1988-04-25 1990-06-12 W. R. Grace & Co.-Conn. Process for forming 3-phenylisoxazolines and 3-phenylisoxazoles
JPH089600B2 (ja) 1988-08-02 1996-01-31 三井東圧化学株式会社 ピラゾールカルボン酸類の製造方法
JPH089599B2 (ja) 1988-08-02 1996-01-31 三井東圧化学株式会社 ピラゾールカルボン酸類の製造方法
IT1228288B (it) 1989-01-09 1991-06-07 Zambon Spa Composti ad attivita' antiserotoninica
DE4016049A1 (de) 1990-05-18 1991-11-21 Basf Ag 3-isoxazolylbenzylester, ihre herstellung und ihre verwendung
US5256632A (en) 1990-05-30 1993-10-26 Bayer Aktiengesellschaft Herbicidal sulphonylated carboxamides
DK178590D0 (da) 1990-07-26 1990-07-26 Novo Nordisk As 1,4-disubstituerede piperaziner
US5260322A (en) 1990-10-08 1993-11-09 Merck & Co., Inc. Angiotension II antagonists in the treatment of hyperuricemia
JP3010387B2 (ja) 1991-05-13 2000-02-21 コニカ株式会社 ピラゾール誘導体
JP3454531B2 (ja) 1991-11-07 2003-10-06 三共株式会社 ニトロキシアルキルアミド誘導体
DE4137940A1 (de) 1991-11-18 1993-05-19 Basf Ag 3-isoxazolylphenylverbindungen, ihre herstellung und ihre verwendung
WO1994017059A1 (fr) 1993-01-29 1994-08-04 Nippon Soda Co., Ltd. Derive heterocyclique
IT1263751B (it) 1993-02-05 1996-08-27 Mini Ricerca Scient Tecnolog Derivati di esteri arilacetici ad attivita' fungicida
JPH06236057A (ja) 1993-02-10 1994-08-23 Fuji Xerox Co Ltd 電子写真感光体
JPH07304748A (ja) 1993-06-29 1995-11-21 Nissan Chem Ind Ltd アルドキシム誘導体および農園芸用殺菌剤
WO1995011896A1 (en) 1993-10-26 1995-05-04 Nissan Chemical Industries, Ltd. Substituted pyrazole derivative and agrohorticultural fungicide
JP3791015B2 (ja) 1994-03-31 2006-06-28 日産化学工業株式会社 スルホンアミド誘導体の製造方法
JP3329061B2 (ja) 1994-04-19 2002-09-30 三菱化学株式会社 電子写真用感光体
JPH0873436A (ja) 1994-07-06 1996-03-19 Nissan Chem Ind Ltd セミカルバゾン誘導体
US5486534A (en) 1994-07-21 1996-01-23 G. D. Searle & Co. 3,4-substituted pyrazoles for the treatment of inflammation
FR2725988B1 (fr) 1994-10-24 1997-01-24 Roussel Uclaf Nouveaux derives de pyrazolones et pyrazoles acides, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
CN1117080A (zh) 1995-01-11 1996-02-21 刘波 苏云金芽胞杆菌培养基
BR9607035A (pt) 1995-02-13 1997-11-04 Searle & Co Isoxazois substituidos para o tratamento de inflamação
WO1996033994A1 (en) 1995-04-28 1996-10-31 Nippon Soda Co., Ltd. Amino-substituted derivatives, process for the preparation thereof, and herbicide
JPH11507670A (ja) 1995-06-12 1999-07-06 ジー．ディー．サール アンド カンパニー シクロオキシゲナーゼ−２インヒビターと５−リポキシゲナーゼインヒビターの組合せによる炎症と炎症関連疾患の治療
JP2000510816A (ja) 1995-10-17 2000-08-22 ジー．ディー．サール アンド カンパニー シクロオキシゲナーゼ−２の検出法
WO1997029774A1 (en) 1996-02-13 1997-08-21 G.D. Searle & Co. Combinations, having immunosuppressive effects, containing a cyclooxygenase-2 inhibitor and a leukotriene a4 hydrolase inhibitor
IL125849A (en) 1996-04-12 2003-10-31 Searle & Co Substituted benzenesulfonamide derivatives, their preparation and pharmaceutical compositions comprising them
JP3399756B2 (ja) 1996-10-22 2003-04-21 三菱製紙株式会社 平版印刷版の処理方法
CN1117080C (zh) 1997-09-05 2003-08-06 巴斯福股份公司 (杂)芳族羟胺化合物的制备方法
US5972986A (en) 1997-10-14 1999-10-26 G.D. Searle & Co. Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia
CA2372912C (en) 1997-10-14 2008-12-02 G.D. Searle & Co. Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia
JPH11124306A (ja) 1997-10-22 1999-05-11 Nissan Chem Ind Ltd 殺虫・殺ダニ・殺菌剤組成物
ATE315033T1 (de) 1998-08-07 2006-02-15 Chiron Corp Subtituierte isoxazole derivate als estrogen rezeptor modulatore
AU1199600A (en) 1998-10-02 2000-04-26 Board Of Trustees Of The University Of Illinois, The Estrogen receptor ligands
AU766648B2 (en) 1999-03-17 2003-10-23 Axys Pharmaceuticals, Inc. Compounds and methods for modulation of estrogen receptors
AU3253800A (en) 1999-05-14 2000-11-16 Pfizer Products Inc. Combination therapy for the treatment of migraine
US6413965B1 (en) 1999-06-30 2002-07-02 Pfizer Inc. Compositions and treatment for diabetic complications
CO5190678A1 (es) 1999-06-30 2002-08-29 Pfizer Prod Inc Terapia combinada para el tratamiento de la migrana
JP4645871B2 (ja) 1999-09-24 2011-03-09 日本農薬株式会社 イソキサゾリン誘導体及び除草剤並びにその使用方法
CA2390113A1 (en) 1999-12-02 2001-06-07 Maurizio Schwarzenbach Aminoheterocyclylamides as pesticides and antiparasitic agents
WO2001081333A2 (en) 2000-04-25 2001-11-01 Pharmacia Corporation Regioselective synthesis of 3,4-di(carbocyclyl or heterocyclyl)thiophenes
JP2001302662A (ja) 2000-04-27 2001-10-31 Nissan Chem Ind Ltd アクリロニトリル化合物
DE60120746T2 (de) 2000-11-27 2007-05-24 Merck & Co., Inc. Östrogenrezeptormodulatoren
US6693295B2 (en) 2000-12-25 2004-02-17 Fuji Photo Film Co., Ltd. Indole derivative, material for light-emitting device and light-emitting device using the same
US7276523B2 (en) 2001-03-30 2007-10-02 Smithkline Beecham Corporation Aminopyridine derivatives as estrogen receptor modulators
US6673818B2 (en) 2001-04-20 2004-01-06 Pharmacia Corporation Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
EP1270535A3 (de) 2001-06-20 2004-02-18 Clariant GmbH Verfahren zur Herstellung von substituierten aromatischen Verbindungen
US6960607B2 (en) 2001-12-13 2005-11-01 Wyeth Naphthyl benzoxazoles and benzisoxazoles as estrogenic agents
US6884814B2 (en) 2001-12-13 2005-04-26 Wyeth Phenyl benzisoxazoles as estrogenic agents
GB0130339D0 (en) 2001-12-19 2002-02-06 Lilly Co Eli Isochroman compounds
ATE374753T1 (de) 2001-12-21 2007-10-15 Vernalis Cambridge Ltd 3-(2,4)dihydroxyphenyl-4-phenylpyrazole und deren medizinische verwendung
AU2002367426A1 (en) 2001-12-28 2003-07-24 Takeda Chemical Industries, Ltd. Neurotrophic factor production/secretion accelerator
US6803379B2 (en) 2002-06-04 2004-10-12 Jose A. Fernandez-Pol Pharmacological agents and methods of treatment that inactivate pathogenic prokaryotic and eukaryotic cells and viruses by attacking highly conserved domains in structural metalloprotein and metalloenzyme targets
CN100345863C (zh) 2002-07-03 2007-10-31 奥索-麦克尼尔药品公司 作为雌激素受体调节剂的雌三烯并[3,2－b]/[3,4－c]吡咯衍生物
EP1551820A2 (en) 2002-09-19 2005-07-13 Merck & Co., Inc. Estrogen receptor modulators
EP1577288B1 (en) 2002-12-26 2014-07-23 Eisai R&D Management Co., Ltd. Selective estrogen receptor modulators
WO2004073612A2 (en) 2003-02-13 2004-09-02 Merck & Co. Inc. Estrogen receptor modulators
WO2004073610A2 (en) 2003-02-13 2004-09-02 Merck & Co., Inc. Estrogen receptor modulators
CA2527659A1 (en) 2003-05-31 2005-01-06 Janssen Pharmaceutica N.V. Cyclohexyl derivatives as selective estrogen receptor modulators
WO2005033056A2 (en) 2003-10-08 2005-04-14 Smithkline Beecham Corporation Triphenylethylene compounds as selective estrogen receptor modulators
AU2005240609A1 (en) 2004-05-04 2005-11-17 Acadia Pharmaceuticals Inc. Compounds with activity at estrogen receptor

Also Published As

Publication number Publication date
JP2009520808A (ja) 2009-05-28
EP1966170A2 (en) 2008-09-10
US20070149564A1 (en) 2007-06-28
BRPI0620215A2 (pt) 2011-11-01
AU2006327877A1 (en) 2007-06-28
EA200801407A1 (ru) 2008-10-30
ECSP088533A (es) 2008-07-30
RS20080267A (sr) 2009-05-06
AP2008004481A0 (en) 2008-06-30
PE20070815A1 (es) 2007-08-27
US7470715B2 (en) 2008-12-30
UY30047A1 (es) 2007-07-31
KR20080073346A (ko) 2008-08-08
WO2007072164A2 (en) 2007-06-28
NL2000351C2 (nl) 2007-09-11
US20090131397A1 (en) 2009-05-21
CA2628596A1 (en) 2007-06-28
WO2007072164A3 (en) 2007-10-04
NL2000351A1 (nl) 2007-06-25
AR058611A1 (es) 2008-02-13

Similar Documents

Publication Publication Date Title
NO20091395L (no) Nye tiofenderivater
NO20055135D0 (no) Fenylguinoliner og deres anvendelse som ostrogenreseptormodulatorer
DK1904475T3 (da) N-thioanthranilamid-forbindelser og deres anvendelse som pesticider
DK1735286T3 (da) Tetrahydroindazoler som cannabinoidmodulatorer
NO20084850L (no) MGLUR5 modulatorer I
DK1660491T3 (da) Benzimidazol-, benzthiazol- og benzoxazolderivater og deres anvendelse som LTA4Hmodulatorer
DK1789401T3 (da) Isoxazolinderivater og deres anvendelse som herbicider
CY1110491T1 (el) Διαμορφωτες του υποδοχεα γλυκοκορτικοειδους αζαδεκαλινης
DK1594867T3 (da) Phenylacetamider og deres anvendelse som glucokinasemodulatorer
SG10201809390QA (en) Modulators of indoleamine 2,3-dioxygenase and methods of using the same
CR11548A (es) Azolilmetiloxiranos, su uso y agentes que los contienen
EA200900781A1 (ru) 4-фенилпиран-3,5-дионы, 4-фенилтиопиран-3,5-дионы и циклогексантрионы, как новые гербициды
NO20090994L (no) 2-aminobenzoxazol karboxamider som 5HT3 modulatorer
NO20076001L (no) Tigecyklin og metoder for deres fremstilling
CL2008000873A1 (es) Compuestos derivados de pirrolidin amidas; composicion farmaceutica que comprende dichos compuestos; y su uso para tratar trombosis.
NO20084852L (no) MGLUR5 modulatorer V
CL2008002041A1 (es) Compuestos derivados de piperidina; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar ansiedad.
BRPI0518752A2 (pt) 1-alquinil-2-arilàxi-alquil-amidas e uso do mesmo como fungicidas
DK1636228T3 (da) Nye pyridopyraziner og deres anvendelse som kinasemodulatorer
AR059444A1 (es) Composiciones ramnolipidicas y metodos de uso relacionados
DK1928840T3 (da) 1H-pyrazol-4-carboxamider, deres fremstilling og deres anvendelse som 11-beta-hydroxysteroid-dehydrogenaseinhibitorer
CR11157A (es) Derivados de 7-alquinil-1,8-naftiridonas, su preparacion y su aplicacion en terapeutica
EA200900780A1 (ru) Аналоги эпотилона, модифицированные в положениях c12-c13, как противораковые лекарственные средства
BRPI0606358A2 (pt) uso de pelo menos um aminoditiol, processo e kit para a deformação permanente dos cabelos e aminotióis
NO20084290L (no) Process to prepare sulfonyl chloride derivatives

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application