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NO20081034L - Pyrimidinforbindelser som serotoninreseptormodulatorer - Google Patents

Pyrimidinforbindelser som serotoninreseptormodulatorer

Info

Publication number
NO20081034L
NO20081034L NO20081034A NO20081034A NO20081034L NO 20081034 L NO20081034 L NO 20081034L NO 20081034 A NO20081034 A NO 20081034A NO 20081034 A NO20081034 A NO 20081034A NO 20081034 L NO20081034 L NO 20081034L
Authority
NO
Norway
Prior art keywords
receptor modulators
serotonin receptor
pyrimidine compounds
serotonin
pyrimidine
Prior art date
Application number
NO20081034A
Other languages
English (en)
Other versions
NO340744B1 (no
Inventor
Curt A Dvorak
Dale A Rudolph
Brock T Shireman
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO20081034L publication Critical patent/NO20081034L/no
Publication of NO340744B1 publication Critical patent/NO340744B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
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    • C07D239/72—Quinazolines; Hydrogenated quinazolines
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
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Abstract

Visse pyrimidinholdige forbindelser representert ved formel (I) og (II) er serotoninreseptormodulatorer nyttige i behandlingen av serotoninmedierte sykdommer.
NO20081034A 2005-08-04 2008-02-27 Pyrimidinforbindelser som serotoninreseptormodulatorer NO340744B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70571905P 2005-08-04 2005-08-04
PCT/US2006/029437 WO2007019083A1 (en) 2005-08-04 2006-07-27 Pyrimidine compounds as serotonin receptor modulators

Publications (2)

Publication Number Publication Date
NO20081034L true NO20081034L (no) 2008-02-28
NO340744B1 NO340744B1 (no) 2017-06-12

Family

ID=37400981

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20081034A NO340744B1 (no) 2005-08-04 2008-02-27 Pyrimidinforbindelser som serotoninreseptormodulatorer

Country Status (16)

Country Link
EP (1) EP1928461B1 (no)
JP (1) JP5066088B2 (no)
KR (1) KR101353268B1 (no)
CN (1) CN101277700B (no)
AT (1) ATE539753T1 (no)
AU (1) AU2006278759B2 (no)
BR (1) BRPI0614397A2 (no)
CA (1) CA2617760C (no)
CR (1) CR9791A (no)
EA (1) EA014495B1 (no)
IL (2) IL189164A (no)
NO (1) NO340744B1 (no)
NZ (1) NZ565334A (no)
UA (1) UA95247C2 (no)
WO (1) WO2007019083A1 (no)
ZA (1) ZA200802010B (no)

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SI1668014T1 (sl) 2003-09-17 2009-06-30 Janssen Pharmaceutica Nv Kondenzirane heterociklične spojine kot modulatorji serotoninskih receptorjev
US7598255B2 (en) 2005-08-04 2009-10-06 Janssen Pharmaceutica Nv Pyrimidine compounds as serotonin receptor modulators
PE20080145A1 (es) * 2006-03-21 2008-02-11 Janssen Pharmaceutica Nv Tetrahidro-pirimidoazepinas como moduladores de trpv1
AU2008231543B2 (en) * 2007-03-23 2011-07-28 Pfizer Limited Pyrimido [4, 5-D] azepine derivatives as 5-HT2C agonists
US8288397B2 (en) 2007-12-17 2012-10-16 Janssen Pharmaceutica Nv Imidazolo-, oxazolo-, and thiazolopyrimidine modulators of TRPV1
NZ603792A (en) * 2010-05-21 2015-07-31 Abbvie Inc Modulators of 5-ht receptors and methods of use thereof
DK3150599T3 (en) * 2014-05-29 2019-01-14 Taiho Pharmaceutical Co Ltd HIS UNKNOWN TETRAHYDROPYRIDOPYRIMIDE COMPOUND OR SALT THEREOF
CN107365314B (zh) * 2016-05-11 2024-09-27 国药集团国瑞药业有限公司 一种吡唑类化合物、其晶型及其制备方法
KR102590403B1 (ko) * 2016-11-15 2023-10-16 템플 유니버시티-오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 5-히드록시트립타민 수용체 7의 신규 조절제 및 이의 사용 방법
MA48803A (fr) 2017-05-31 2020-04-08 Chemocentryx Inc Cycles 6-5 fusionnés utilisés en tant qu'inhibiteurs de c5a
ES2980175T3 (es) * 2017-12-22 2024-09-30 Chemocentryx Inc Compuestos anulares fusionados en 6,5 sustituidos con diarilo como inhibidores de C5aR
MY208662A (en) 2018-04-18 2025-05-22 Constellation Pharmaceuticals Inc Modulators of methyl modifying enzymes, compositions and uses thereof
CN120097995A (zh) 2018-05-21 2025-06-06 星座制药公司 甲基修饰酶的调节剂、其组合物和用途
KR102282569B1 (ko) * 2019-02-08 2021-07-29 (주)퓨쳐켐 새로운 18F-표지된 친디엔체와 테트라진 화합물과의 IeDDA 반응을 이용한 18F-표지 방법
WO2021016414A1 (en) 2019-07-24 2021-01-28 Constellation Pharmaceuticals, Inc. Crystalline forms of 7-chloro-2-(4-(3-methoxyazetidin-1-yl)cyclohexyl)-2,4-dimethyl-n-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)benzo[d][1,3]dioxole-5-carboxamide
KR102483495B1 (ko) * 2019-09-02 2023-01-04 한양대학교 에리카산학협력단 2,4-이치환된 피리미딘 유도체 및 이를 포함하는 약학적 조성물
CN119060064A (zh) * 2019-11-13 2024-12-03 英联邦高等教育系统坦普尔大学 作为5-羟色胺受体7调节剂的新型官能化内酯及其使用方法
CN117120429A (zh) 2021-03-29 2023-11-24 吉利德科学公司 Khk抑制剂
AR128432A1 (es) * 2022-02-02 2024-05-08 The Katholieke Univ Leuven Tetrahidropiridopirimidinas y análogos relacionados para la inhibición de yap / taz-tead

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AU2006278759A1 (en) 2007-02-15
ATE539753T1 (de) 2012-01-15
BRPI0614397A2 (pt) 2011-03-29
CR9791A (es) 2010-05-27
EP1928461A1 (en) 2008-06-11
WO2007019083A1 (en) 2007-02-15
ZA200802010B (en) 2009-09-30
CA2617760C (en) 2015-02-17
UA95247C2 (ru) 2011-07-25
KR101353268B1 (ko) 2014-02-06
EA014495B1 (ru) 2010-12-30
CN101277700A (zh) 2008-10-01
AU2006278759B2 (en) 2012-08-16
CN101277700B (zh) 2013-02-20
KR20080033502A (ko) 2008-04-16
JP5066088B2 (ja) 2012-11-07
CA2617760A1 (en) 2007-02-15
IL189164A (en) 2013-08-29
NZ565334A (en) 2010-12-24
HK1118469A1 (en) 2009-02-13
JP2009503076A (ja) 2009-01-29
EP1928461B1 (en) 2012-01-04
NO340744B1 (no) 2017-06-12
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