NO20076014L - Fremgangsmate for behandling av demens eller Alzheimers sykdom - Google Patents
Fremgangsmate for behandling av demens eller Alzheimers sykdomInfo
- Publication number
- NO20076014L NO20076014L NO20076014A NO20076014A NO20076014L NO 20076014 L NO20076014 L NO 20076014L NO 20076014 A NO20076014 A NO 20076014A NO 20076014 A NO20076014 A NO 20076014A NO 20076014 L NO20076014 L NO 20076014L
- Authority
- NO
- Norway
- Prior art keywords
- dementia
- disease
- procedures
- alzheimer
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Sammendrag Fremgangsmåter for å behandle Alzheimers sykdom (AD) eller demens ved å benytte et CD20-antistoff blir beskrevet. Fremstilte artikler til anvendelse i slike fremgangsmåter er også beskrevet.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67402805P | 2005-04-22 | 2005-04-22 | |
| PCT/US2006/015577 WO2006116369A2 (en) | 2005-04-22 | 2006-04-20 | Method for treating dementia or alzheimer's disease with a cd20 antibody |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20076014L true NO20076014L (no) | 2008-01-18 |
Family
ID=37215396
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20076014A NO20076014L (no) | 2005-04-22 | 2007-11-21 | Fremgangsmate for behandling av demens eller Alzheimers sykdom |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20060240007A1 (no) |
| EP (1) | EP1874350A2 (no) |
| JP (1) | JP2008538767A (no) |
| KR (1) | KR20070122497A (no) |
| CN (1) | CN101203242A (no) |
| AU (1) | AU2006238812A1 (no) |
| BR (1) | BRPI0612972A2 (no) |
| CA (1) | CA2607475A1 (no) |
| IL (1) | IL186333A0 (no) |
| MX (1) | MX2007012989A (no) |
| NO (1) | NO20076014L (no) |
| RU (1) | RU2007143302A (no) |
| WO (1) | WO2006116369A2 (no) |
| ZA (1) | ZA200708857B (no) |
Families Citing this family (67)
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| MXPA01011279A (es) | 1999-05-07 | 2002-07-02 | Genentech Inc | Tratamiento de enfermedades autoinmunes con antagonistas que se unene a los marcadores de superficie, de celulas b. |
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| ES2708095T3 (es) | 2003-11-05 | 2019-04-08 | Roche Glycart Ag | Anticuerpos de CD20 con afinidad de unión a receptor de Fc y función efectora incrementadas |
| CA2628703C (en) | 2005-11-30 | 2019-10-29 | Abbott Laboratories | Anti-a.beta. globulomer antibodies, antigen-binding moieties thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods of producing said antibodies, compositions comprising said antibodies, uses of said antibodies and methods of using said antibodies |
| EP1976877B2 (en) | 2005-11-30 | 2016-10-05 | AbbVie Inc. | Monoclonal antibodies against amyloid beta protein and uses thereof |
| CA2667802A1 (en) * | 2006-11-03 | 2008-05-29 | Northwestern University | Multiple sclerosis therapy |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| US20100189723A1 (en) | 2007-01-11 | 2010-07-29 | Peter Andreas Nicolai Reumert Wagtmann | Anti-kir antibodies, formulations, and uses thereof |
| EP2124952A2 (en) | 2007-02-27 | 2009-12-02 | Abbott GmbH & Co. KG | Method for the treatment of amyloidoses |
| EP2137171A4 (en) | 2007-03-14 | 2010-05-19 | Knopp Neurosciences Inc | SYNTHESIS OF BENZOTHIAZOLE DIAMINES SUBSTITUTED AND PURIFIED FROM THE CHIRAL PERSPECTIVE |
| US8383865B2 (en) * | 2007-04-17 | 2013-02-26 | Codman & Shurtleff, Inc. | Curcumin derivatives |
| EP2749552B1 (en) * | 2007-04-17 | 2015-11-18 | Codman & Shurtleff, Inc. | Curcumin-resveratrol hybrids |
| NZ583019A (en) * | 2007-07-31 | 2011-05-27 | Regeneron Pharma | Human antibodies to human cd20 and method of using thereof |
| US7745670B2 (en) * | 2008-06-27 | 2010-06-29 | Codman & Shurtleff, Inc. | Curcumin-Resveratrol hybrid molecule |
| US7985776B2 (en) | 2008-06-27 | 2011-07-26 | Codman & Shurtleff, Inc. | Iontophoretic delivery of curcumin and curcumin analogs for the treatment of Alzheimer's Disease |
| CA2731255C (en) * | 2008-07-21 | 2018-06-05 | David M. Goldenberg | Structural variants of antibodies for improved therapeutic characteristics |
| WO2010022140A1 (en) * | 2008-08-19 | 2010-02-25 | Knopp Neurosciences, Inc. | Compositions and methods of using (r)-pramipexole |
| AR073295A1 (es) | 2008-09-16 | 2010-10-28 | Genentech Inc | Metodos para tratar la esclerosis multiple progresiva. articulo de fabricacion. |
| EP2373660B1 (en) | 2008-12-10 | 2016-08-17 | WisTa Laboratories Ltd. | 3,6-disubstituted xanthylium salts as medicaments |
| US7723515B1 (en) * | 2009-01-26 | 2010-05-25 | Codman & Shurtleff, Inc. | Methylene blue—curcumin analog for the treatment of alzheimer's disease |
| US20100286585A1 (en) * | 2009-01-26 | 2010-11-11 | Codman & Shurtleff, Inc. | Shunt Delivery of Curcumin |
| US9925282B2 (en) | 2009-01-29 | 2018-03-27 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| AR078161A1 (es) * | 2009-09-11 | 2011-10-19 | Hoffmann La Roche | Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento. |
| US8987419B2 (en) | 2010-04-15 | 2015-03-24 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
| US20130336961A1 (en) * | 2010-07-16 | 2013-12-19 | The Ohio State University | B Cell Depletion for Central Nervous System Injuries and Methods and Uses Thereof |
| MX358739B (es) | 2010-08-14 | 2018-09-03 | Abbvie Inc Star | Proteinas de union a amiloide beta. |
| US9884909B2 (en) | 2010-12-01 | 2018-02-06 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
| US9539324B2 (en) | 2010-12-01 | 2017-01-10 | Alderbio Holdings, Llc | Methods of preventing inflammation and treating pain using anti-NGF compositions |
| AU2011336470B8 (en) | 2010-12-01 | 2017-09-14 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
| US9078878B2 (en) | 2010-12-01 | 2015-07-14 | Alderbio Holdings Llc | Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75 |
| US9067988B2 (en) | 2010-12-01 | 2015-06-30 | Alderbio Holdings Llc | Methods of preventing or treating pain using anti-NGF antibodies |
| US11214610B2 (en) | 2010-12-01 | 2022-01-04 | H. Lundbeck A/S | High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris |
| WO2013096816A1 (en) | 2011-12-22 | 2013-06-27 | Biogen Idec Ma Inc. | Improved synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds |
| PL3354751T3 (pl) * | 2012-08-21 | 2020-03-31 | Janssen Pharmaceutica Nv | Przeciwciała dla arypiprazolu i ich zastosowanie |
| PL2888593T3 (pl) * | 2012-08-21 | 2019-02-28 | Janssen Pharmaceutica Nv | Przeciwciała przeciwko rysperydonowi i ich zastosowanie |
| JOP20200236A1 (ar) | 2012-09-21 | 2017-06-16 | Regeneron Pharma | الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها |
| US10058530B2 (en) | 2012-10-25 | 2018-08-28 | The General Hospital Corporation | Combination therapies for the treatment of Alzheimer's disease and related disorders |
| CN104869993B (zh) | 2012-10-25 | 2019-01-15 | 通用医疗公司 | 治疗阿尔茨海默病及相关疾病的组合疗法 |
| US9662313B2 (en) | 2013-02-28 | 2017-05-30 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
| ES2798307T3 (es) | 2013-03-15 | 2020-12-10 | Hoffmann La Roche | Composiciones de cultivo de células con antioxidantes y procedimientos para la producción de polipéptidos |
| US9879076B2 (en) * | 2013-03-15 | 2018-01-30 | Ramot At Tel Aviv University Ltd. | Methods and compositions with immune therapy for treatment of dementia |
| US10525005B2 (en) | 2013-05-23 | 2020-01-07 | The General Hospital Corporation | Cromolyn compositions and methods thereof |
| EP3019167B1 (en) | 2013-07-12 | 2021-02-17 | Knopp Biosciences LLC | Treating elevated levels of eosinophils and/or basophils |
| US9468630B2 (en) | 2013-07-12 | 2016-10-18 | Knopp Biosciences Llc | Compositions and methods for treating conditions related to increased eosinophils |
| PL3033081T3 (pl) | 2013-08-13 | 2021-08-30 | Knopp Biosciences Llc | Kompozycje i sposoby do leczenia przewlekłej pokrzywki |
| EP3038467B1 (en) | 2013-08-13 | 2020-07-29 | Knopp Biosciences LLC | Compositions and methods for treating plasma cell disorders and b-cell prolymphocytic disorders |
| AU2014340182B2 (en) | 2013-10-22 | 2019-05-23 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| TWI701042B (zh) | 2014-03-19 | 2020-08-11 | 美商再生元醫藥公司 | 用於腫瘤治療之方法及抗體組成物 |
| HUE071048T2 (hu) | 2014-11-17 | 2025-07-28 | Regeneron Pharma | Daganatkezelési módszerek a CD3XCD20 bispecifikus antitest használatával |
| SG10201913841SA (en) * | 2015-07-24 | 2020-03-30 | Oncotracker Inc | Gamma secretase modulators for the treatment of immune system dysfunction |
| TWI797060B (zh) | 2015-08-04 | 2023-04-01 | 美商再生元醫藥公司 | 補充牛磺酸之細胞培養基及用法 |
| WO2018045217A1 (en) | 2016-08-31 | 2018-03-08 | The General Hospital Corporation | Macrophages/microglia in neuro-inflammation associated with neurodegenerative diseases |
| ES2834085T3 (es) * | 2016-11-10 | 2021-06-16 | Brain Biomarker Solutions In Gothenburg Ab | Métodos para detectar que un individuo está en riesgo de desarrollar una enfermedad neurodegenerativa |
| WO2018154580A1 (en) * | 2017-02-24 | 2018-08-30 | B. G. Negev Technologies And Applications Ltd., At Ben-Gurion University | Fc-based polypeptides and use thereof |
| US20180282784A1 (en) * | 2017-03-31 | 2018-10-04 | NeuroDiagnostics LLC | LYMPHOCYTE-BASED PKCe TEST FOR ALZHEIMER'S DISEASE |
| AU2017423862A1 (en) | 2017-07-20 | 2020-02-06 | Aztherapies, Inc. | Powdered formulations of cromolyn sodium and ibuprofen |
| AU2019299347A1 (en) | 2018-07-02 | 2021-01-21 | Aztherapies, Inc. | Powdered formulations of cromolyn sodium and alpha-lactose |
| PL3844189T3 (pl) | 2018-08-31 | 2025-03-31 | Regeneron Pharmaceuticals, Inc. | Strategia dawkowania, która łagodzi zespół uwalniania cytokin, dla przeciwciał dwuswoistych cd3/cd20 |
| KR20210113610A (ko) | 2018-12-10 | 2021-09-16 | 더 제너럴 하스피탈 코포레이션 | 크로몰린 에스테르 및 이의 용도 |
| CN109738653B (zh) * | 2019-01-11 | 2022-04-12 | 湖南诺琪生物科技有限公司 | 用于阿尔茨海默症的检测、诊断或风险预测的抗原蛋白组合以及包含其的试剂盒 |
| US12297451B1 (en) | 2019-10-25 | 2025-05-13 | Regeneron Pharmaceuticals, Inc. | Cell culture medium |
| JP2023520580A (ja) | 2020-04-06 | 2023-05-17 | ザ ジェネラル ホスピタル コーポレイション | コロナウイルス誘発炎症状態の処置方法 |
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| CN116077524A (zh) * | 2023-02-27 | 2023-05-09 | 广西馨海药业科技有限公司 | 氯化铷在制备治疗帕金森综合征的药物中的用途 |
| CN120324577A (zh) * | 2023-11-13 | 2025-07-18 | 长沙英奈发药业有限公司 | 促天然吞噬多肽在制备治疗阿尔茨海默症药物中的应用 |
| CN117624356B (zh) * | 2024-01-26 | 2024-04-12 | 南京诺唯赞医疗科技有限公司 | NfL特异性抗体及其在阿尔茨海默症辅助诊断试剂盒的应用 |
| CN118987213A (zh) * | 2024-07-16 | 2024-11-22 | 华中科技大学同济医学院附属同济医院 | B细胞耗竭剂在制备治疗血管性认知功能障碍药物中的应用 |
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| US6893625B1 (en) * | 1986-10-27 | 2005-05-17 | Royalty Pharma Finance Trust | Chimeric antibody with specificity to human B cell surface antigen |
| IL85035A0 (en) * | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| US5506126A (en) * | 1988-02-25 | 1996-04-09 | The General Hospital Corporation | Rapid immunoselection cloning method |
| US4861579A (en) * | 1988-03-17 | 1989-08-29 | American Cyanamid Company | Suppression of B-lymphocytes in mammals by administration of anti-B-lymphocyte antibodies |
| PL174721B1 (pl) * | 1992-11-13 | 1998-09-30 | Idec Pharma Corp | Przeciwciało monoklonalne anty-CD20 |
| US5736137A (en) * | 1992-11-13 | 1998-04-07 | Idec Pharmaceuticals Corporation | Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
| US5595721A (en) * | 1993-09-16 | 1997-01-21 | Coulter Pharmaceutical, Inc. | Radioimmunotherapy of lymphoma using anti-CD20 |
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-
2006
- 2006-04-20 MX MX2007012989A patent/MX2007012989A/es not_active Application Discontinuation
- 2006-04-20 RU RU2007143302/14A patent/RU2007143302A/ru not_active Application Discontinuation
- 2006-04-20 CA CA002607475A patent/CA2607475A1/en not_active Abandoned
- 2006-04-20 ZA ZA200708857A patent/ZA200708857B/xx unknown
- 2006-04-20 JP JP2008507995A patent/JP2008538767A/ja not_active Withdrawn
- 2006-04-20 WO PCT/US2006/015577 patent/WO2006116369A2/en not_active Ceased
- 2006-04-20 EP EP06751339A patent/EP1874350A2/en not_active Withdrawn
- 2006-04-20 AU AU2006238812A patent/AU2006238812A1/en not_active Abandoned
- 2006-04-20 BR BRPI0612972-2A patent/BRPI0612972A2/pt not_active IP Right Cessation
- 2006-04-20 KR KR1020077024089A patent/KR20070122497A/ko not_active Withdrawn
- 2006-04-20 CN CNA200680022682XA patent/CN101203242A/zh active Pending
- 2006-04-20 US US11/407,726 patent/US20060240007A1/en not_active Abandoned
-
2007
- 2007-10-07 IL IL186333A patent/IL186333A0/en unknown
- 2007-11-21 NO NO20076014A patent/NO20076014L/no not_active Application Discontinuation
-
2009
- 2009-04-17 US US12/425,537 patent/US20090226439A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008538767A (ja) | 2008-11-06 |
| KR20070122497A (ko) | 2007-12-31 |
| RU2007143302A (ru) | 2009-05-27 |
| MX2007012989A (es) | 2008-01-11 |
| WO2006116369A3 (en) | 2007-08-23 |
| WO2006116369A2 (en) | 2006-11-02 |
| ZA200708857B (en) | 2009-01-28 |
| EP1874350A2 (en) | 2008-01-09 |
| US20060240007A1 (en) | 2006-10-26 |
| IL186333A0 (en) | 2008-01-20 |
| CA2607475A1 (en) | 2006-11-02 |
| US20090226439A1 (en) | 2009-09-10 |
| CN101203242A (zh) | 2008-06-18 |
| BRPI0612972A2 (pt) | 2010-12-14 |
| AU2006238812A1 (en) | 2006-11-02 |
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