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NO20064400L - Prolin-derivater, og anvendelse av samme som inhibitorer av dipeptidyl peptidase IV - Google Patents

Prolin-derivater, og anvendelse av samme som inhibitorer av dipeptidyl peptidase IV

Info

Publication number
NO20064400L
NO20064400L NO20064400A NO20064400A NO20064400L NO 20064400 L NO20064400 L NO 20064400L NO 20064400 A NO20064400 A NO 20064400A NO 20064400 A NO20064400 A NO 20064400A NO 20064400 L NO20064400 L NO 20064400L
Authority
NO
Norway
Prior art keywords
inhibitors
same
dipeptidyl peptidase
proline derivatives
diabetic
Prior art date
Application number
NO20064400A
Other languages
English (en)
Inventor
David Walter Piotrowski
Bernard Hulin
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34966115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20064400(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO20064400L publication Critical patent/NO20064400L/no

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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D498/04—Ortho-condensed systems

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  • Rheumatology (AREA)
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Abstract

Det beskrives forbindelser av formel (I), prodrug og stereoisomerer derav, og farmasøytisk akseptable salter av forbindelsene, prodrugene og stereoisomerene, hvor R1, R2, R3, HET, n, Q, X, Y, og Z er som beskrevet heri; sammensetninger derav; og anvendelse derav for å behandle diabetiske komplikasjoner inkluderende diabetisk neuropati, diabetisk nefropati, diabetisk mikroangiopati, og lignende.
NO20064400A 2004-05-12 2006-09-28 Prolin-derivater, og anvendelse av samme som inhibitorer av dipeptidyl peptidase IV NO20064400L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57030004P 2004-05-12 2004-05-12
US66430505P 2005-03-21 2005-03-21
PCT/IB2005/001194 WO2005116014A1 (en) 2004-05-12 2005-04-29 Proline derivatives and their use as dipeptidyl peptidase iv inhibitors

Publications (1)

Publication Number Publication Date
NO20064400L true NO20064400L (no) 2006-10-25

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ID=34966115

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20064400A NO20064400L (no) 2004-05-12 2006-09-28 Prolin-derivater, og anvendelse av samme som inhibitorer av dipeptidyl peptidase IV

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EP (2) EP1753748B1 (no)
JP (1) JP4227660B2 (no)
KR (1) KR100869616B1 (no)
AP (1) AP2320A (no)
AR (1) AR049894A1 (no)
AT (1) ATE437870T1 (no)
AU (1) AU2005247684B2 (no)
BR (1) BRPI0510284A (no)
CA (1) CA2566108C (no)
CR (1) CR8744A (no)
CY (1) CY1109322T1 (no)
DE (1) DE602005015699D1 (no)
DK (1) DK1753748T3 (no)
EA (1) EA011086B9 (no)
EC (1) ECSP066985A (no)
ES (1) ES2327857T3 (no)
GE (1) GEP20084421B (no)
HR (1) HRP20090471T1 (no)
IL (1) IL178339A (no)
MA (1) MA28578B1 (no)
MX (1) MXPA06013114A (no)
MY (1) MY139805A (no)
NL (1) NL1029015C2 (no)
NO (1) NO20064400L (no)
NZ (1) NZ550229A (no)
PA (1) PA8632701A1 (no)
PE (1) PE20060316A1 (no)
PL (1) PL1753748T3 (no)
PT (1) PT1753748E (no)
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SI (1) SI1753748T1 (no)
SV (1) SV2006002110A (no)
TW (1) TWI347322B (no)
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WO (1) WO2005116014A1 (no)

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US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
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JP4227660B2 (ja) 2004-05-12 2009-02-18 ファイザー・プロダクツ・インク ジペプチジルペプチダーゼｉｖインヒビターとしてのプロリン誘導体およびそれらの使用
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
WO2006071875A1 (en) 2004-12-29 2006-07-06 Millennium Pharmaceuticals, Inc. Compounds useful as chemokine receptor antagonists
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WO2006073167A1 (ja) * 2005-01-07 2006-07-13 Ono Pharmaceutical Co., Ltd. ピロリジン誘導体
DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
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