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NO20091590L - Heterocykliske amidforbindelser anvendbare som kinaseinhibitorer - Google Patents

Heterocykliske amidforbindelser anvendbare som kinaseinhibitorer

Info

Publication number
NO20091590L
NO20091590L NO20091590A NO20091590A NO20091590L NO 20091590 L NO20091590 L NO 20091590L NO 20091590 A NO20091590 A NO 20091590A NO 20091590 A NO20091590 A NO 20091590A NO 20091590 L NO20091590 L NO 20091590L
Authority
NO
Norway
Prior art keywords
kinase inhibitors
compounds useful
amide compounds
heterocyclic amide
formula
Prior art date
Application number
NO20091590A
Other languages
English (en)
Inventor
James Lin
Stephen T Wrobleski
John Hynes
T G Murali Dhar
Jagabandhu Das
Alaric Dyckman
Katerina Leftheris
Shuqun Lin
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO20091590L publication Critical patent/NO20091590L/no

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    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
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Abstract

Forbindelse med formel I og enantiomerer, diastereomerer og farmasøytisk akseptable salter derav. Også beskrevet er farmasøytiske preparater inneholdende forbindelser med formel I og metoder for behandling av lidelser forbundet med aktiviteten til p38 kinase.
NO20091590A 2006-10-27 2009-04-22 Heterocykliske amidforbindelser anvendbare som kinaseinhibitorer NO20091590L (no)

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JP2010508288A (ja) 2010-03-18
US8404689B2 (en) 2013-03-26
EP2083816A2 (en) 2009-08-05
US20110160207A1 (en) 2011-06-30
WO2008057775A3 (en) 2008-07-31
EP2468717A1 (en) 2012-06-27
EP2468717B1 (en) 2013-11-20
WO2008057775A2 (en) 2008-05-15
US7935696B2 (en) 2011-05-03
US20080171741A1 (en) 2008-07-17

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