NO20063230L - CRF receptorantagonister og fremgangsmater for fremstilling derav - Google Patents

CRF receptorantagonister og fremgangsmater for fremstilling derav

Info

Publication number: NO20063230L
Authority: NO; Norway
Prior art keywords: crf receptor; receptor antagonists; methods; preparation; crf
Prior art date: 2003-12-22

Application number

NO20063230A

Other languages

English (en)

Norwegian (no)

Inventor

Deborah Slee

Zhiyong Luo

John Edward Tellew

John Williams

Xiaohu Zhang

Original Assignee

Sb Pharmco Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-12-22

Filing date

2006-07-11

Publication date

2006-09-12

2006-07-11 Application filed by Sb Pharmco Inc filed Critical Sb Pharmco Inc

2006-09-12 Publication of NO20063230L publication Critical patent/NO20063230L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Diabetes (AREA)
Psychiatry (AREA)
Child & Adolescent Psychology (AREA)
Obesity (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO20063230A 2003-12-22 2006-07-11 CRF receptorantagonister og fremgangsmater for fremstilling derav NO20063230L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US53203103P	2003-12-22	2003-12-22
PCT/IB2004/004234 WO2005063755A1 (fr)	2003-12-22	2004-12-20	Antagonistes du recepteur de crf et procedes correspondants

Publications (1)

Publication Number	Publication Date
NO20063230L true NO20063230L (no)	2006-09-12

Family

ID=34738733

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20063230A NO20063230L (no)	2003-12-22	2006-07-11	CRF receptorantagonister og fremgangsmater for fremstilling derav

Country Status (19)

Country	Link
US (1)	US7737154B2 (fr)
EP (1)	EP1697374B1 (fr)
JP (1)	JP4926720B2 (fr)
KR (1)	KR20070009537A (fr)
CN (1)	CN1938309B (fr)
AR (1)	AR046967A1 (fr)
AU (1)	AU2004309168B2 (fr)
BR (1)	BRPI0417943A (fr)
CA (1)	CA2550948A1 (fr)
IL (1)	IL176350A0 (fr)
IS (1)	IS8526A (fr)
MA (1)	MA29984B1 (fr)
MY (1)	MY143499A (fr)
NO (1)	NO20063230L (fr)
NZ (1)	NZ547990A (fr)
RU (1)	RU2394035C2 (fr)
TW (1)	TW200530242A (fr)
WO (1)	WO2005063755A1 (fr)
ZA (1)	ZA200604574B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0308208D0 (en)	2003-04-09	2003-05-14	Glaxo Group Ltd	Chemical compounds
US8815599B2 (en)	2004-06-01	2014-08-26	Pronai Therapeutics, Inc.	Methods and compositions for the inhibition of gene expression
JP2008517060A (ja) *	2004-10-19	2008-05-22	エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド	Ｃｒｆ受容体アンタゴニストおよびその製法
GB0519957D0 (en)	2005-09-30	2005-11-09	Sb Pharmco Inc	Chemical compound
US8088779B2 (en) *	2005-09-30	2012-01-03	Smithkline Beecham (Cork) Limited	Pyrazolo [1,5-alpha] pyrimidinyl derivatives useful as corticotropin-releasing factor (CRF) receptor antagonists
AU2007297421B2 (en)	2006-09-20	2012-03-08	Eli Lilly And Company	Thiazole pyrazolopyrimidines as CRF1 receptor antagonists
CA2662000C (fr)	2006-09-20	2013-01-08	Eli Lilly And Company	Composes de thiophene pyrazolopyrimidine
KR100854679B1 (ko) *	2007-02-03	2008-08-27	김기형	심플 서비스 로케이션 프로토콜 네트워크 시스템 및 이를구성하는 에이전트.
EP2282998B1 (fr) *	2008-04-21	2014-09-10	Albemarle Corporation	Procédés de production du n-alkylpyrazole
CN102753527B (zh) *	2010-02-02	2014-12-24	诺华股份有限公司	用作crf受体拮抗剂的环己基酰胺衍生物
WO2014060381A1 (fr)	2012-10-18	2014-04-24	Bayer Cropscience Ag	Composés hétérocycliques pour la lutte contre les nuisibles
BR112015009751A2 (pt)	2012-10-31	2017-07-11	Bayer Cropscience Ag	novos compostos heterocíclicos como pesticidas
US9856262B2 (en) *	2014-04-10	2018-01-02	Hubei Bio-Pharmaceutical Industrial Technological Institute Inc.	Analogues of 4H-pyrazolo[1,5-a] benzimidazole compound as PARP inhibitors
CN110996943A (zh)	2017-08-14	2020-04-10	云杉生物科学公司	促肾上腺皮质激素释放因子受体拮抗剂
KR20230092870A (ko) *	2020-07-27	2023-06-26	에스팜 바이오테크 피티와이 엘티디	화합물
KR20240023691A (ko)	2020-08-12	2024-02-22	스프루스 바이오사이언시스 인코포레이티드	다낭성 난소 증후군을 치료하기 위한 방법 및 조성물
US11708372B2 (en)	2021-11-19	2023-07-25	Spruce Biosciences, Inc.	Crystalline composition of tildacerfont and methods of use and preparation thereof

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2168237T3 (es) *	1996-02-07	2007-04-01	Neurocrine Biosciences, Inc.	Pirazolopirimidinas como antagonistas de receptores de crf.
PT915880E (pt)	1996-07-24	2007-12-31	Bristol Myers Squibb Pharma Co	Azol triazinas e pirimidinas
US6060478A (en)	1996-07-24	2000-05-09	Dupont Pharmaceuticals	Azolo triazines and pyrimidines
US6313124B1 (en) *	1997-07-23	2001-11-06	Dupont Pharmaceuticals Company	Tetrazine bicyclic compounds
CN1227554A (zh)	1996-08-28	1999-09-01	辉瑞大药厂	取代的6,5－杂二环衍生物
CA2291709A1 (fr) *	1997-05-30	1998-12-03	Merck & Co., Inc.	Nouveaux inhibiteurs d'angiogenese
ATE301657T1 (de) *	1998-01-28	2005-08-15	Bristol Myers Squibb Pharma Co	Azolo-pyrimidine
WO2000059908A2 (fr)	1999-04-06	2000-10-12	Du Pont Pharmaceuticals Company	Pyrazolopyrimidines antagonistes de corticoliberine (crf)
CA2379633C (fr)	1999-09-30	2006-06-20	Neurogen Corporation	Pyrazolo[1,5,-a]-1,5-pyrimidines et pyrazolo[1,5-a]-1,3,5-triazines amino substituees
CO5271670A1 (es)	1999-10-29	2003-04-30	Pfizer Prod Inc	Antagonistas del factor de liberacion de corticitropina y composiciones relacionadas
MXPA03009938A (es)	2001-04-30	2005-09-07	Glaxo Group Ltd	Pirimidinas fusionadas como antagonistas del factor liberador de corticotropina.
EP1395591B1 (fr)	2001-06-12	2008-06-04	Glaxo Group Limited	Antagonistes du facteur de liberation de la corticotropine
GB0117396D0 (en)	2001-07-17	2001-09-05	Glaxo Group Ltd	Chemical compounds
ES2285409T3 (es)	2003-01-16	2007-11-16	Sb Pharmco Puerto Rico Inc	Derivados pirrol(2,3-b)piridina sustituidos con heteroarilo como antagonistas del receptor de crf.
WO2004087707A1 (fr)	2003-03-31	2004-10-14	Vernalis (Cambridge) Limited	Composes pyrazolopyrimidines et leur utilisation en medecine
GB0308208D0 (en)	2003-04-09	2003-05-14	Glaxo Group Ltd	Chemical compounds
US20070021429A1 (en)	2003-04-09	2007-01-25	Yves St-Denis	Condensed n-heterocyclic compounds and their use as crf receptor antagonists
US20070293511A1 (en)	2003-12-22	2007-12-20	Sb Pharmco Puerto Rico Inc. And Neurocrine Biosciences, Inc., A Corporation	Crf Receptor Antagonists and Methods
DE102004008807A1 (de)	2004-02-20	2005-09-08	Bayer Cropscience Ag	Pyrazolopyrimidine
GB0519957D0 (en)	2005-09-30	2005-11-09	Sb Pharmco Inc	Chemical compound
JP2008517060A (ja)	2004-10-19	2008-05-22	エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド	Ｃｒｆ受容体アンタゴニストおよびその製法
US8088779B2 (en)	2005-09-30	2012-01-03	Smithkline Beecham (Cork) Limited	Pyrazolo [1,5-alpha] pyrimidinyl derivatives useful as corticotropin-releasing factor (CRF) receptor antagonists

2004
- 2004-12-20 CN CN2004800420125A patent/CN1938309B/zh not_active Expired - Fee Related
- 2004-12-20 JP JP2006546391A patent/JP4926720B2/ja not_active Expired - Fee Related
- 2004-12-20 US US10/596,648 patent/US7737154B2/en active Active
- 2004-12-20 KR KR1020067012368A patent/KR20070009537A/ko not_active Ceased
- 2004-12-20 AR ARP040104790A patent/AR046967A1/es not_active Application Discontinuation
- 2004-12-20 RU RU2006126675/04A patent/RU2394035C2/ru not_active IP Right Cessation
- 2004-12-20 TW TW093139578A patent/TW200530242A/zh unknown
- 2004-12-20 CA CA002550948A patent/CA2550948A1/fr not_active Abandoned
- 2004-12-20 AU AU2004309168A patent/AU2004309168B2/en not_active Ceased
- 2004-12-20 NZ NZ547990A patent/NZ547990A/en unknown
- 2004-12-20 WO PCT/IB2004/004234 patent/WO2005063755A1/fr not_active Ceased
- 2004-12-20 MY MYPI20045253A patent/MY143499A/en unknown
- 2004-12-20 EP EP04820857A patent/EP1697374B1/fr not_active Expired - Lifetime
- 2004-12-20 BR BRPI0417943-9A patent/BRPI0417943A/pt not_active Application Discontinuation
2006
- 2006-06-05 ZA ZA200604574A patent/ZA200604574B/en unknown
- 2006-06-15 IL IL176350A patent/IL176350A0/en unknown
- 2006-06-27 MA MA29147A patent/MA29984B1/fr unknown
- 2006-07-11 IS IS8526A patent/IS8526A/is unknown
- 2006-07-11 NO NO20063230A patent/NO20063230L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
MA29984B1 (fr)	2008-12-01
CN1938309B (zh)	2011-11-09
RU2006126675A (ru)	2008-01-27
IS8526A (is)	2006-07-11
JP4926720B2 (ja)	2012-05-09
JP2007515472A (ja)	2007-06-14
RU2394035C2 (ru)	2010-07-10
BRPI0417943A (pt)	2007-04-17
EP1697374B1 (fr)	2012-08-29
AU2004309168B2 (en)	2009-04-23
WO2005063755A1 (fr)	2005-07-14
EP1697374A1 (fr)	2006-09-06
US7737154B2 (en)	2010-06-15
US20070287705A1 (en)	2007-12-13
AR046967A1 (es)	2006-01-04
CA2550948A1 (fr)	2005-07-14
TW200530242A (en)	2005-09-16
AU2004309168A1 (en)	2005-07-14
ZA200604574B (en)	2007-11-28
CN1938309A (zh)	2007-03-28
IL176350A0 (en)	2006-10-05
NZ547990A (en)	2010-04-30
KR20070009537A (ko)	2007-01-18
MY143499A (en)	2011-05-31

Publication	Publication Date	Title
NO20063230L (no)	2006-09-12	CRF receptorantagonister og fremgangsmater for fremstilling derav
HRP20080666T3 (en)	2009-01-31	Cgrp receptor antagonists
NO20070555L (no)	2007-01-30	Kinazolinonderivater som parp-inhibitorer
WO2006044821A8 (fr)	2006-08-24	Antagonistes du recepteur du crf et procedes associes
MX2009004900A (es)	2009-05-19	Arilamidas sustituidas por tiazol u oxazol.
MXPA05009508A (es)	2005-12-14	Derivados de nicotinamida 6-substituida como antagonistas de receptor opioide.
MX2009005217A (es)	2009-07-31	Compuestos heterociclicos que contienen nitrogeno y metodos de uso de los mismos.
NO20070445L (no)	2007-01-24	Pyrimidinderivater.
TW200606151A (en)	2006-02-16	Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions
TW200626599A (en)	2006-08-01	CRF receptor antagonists and methods relating thereto
SG154443A1 (en)	2009-08-28	Piperidine derivatives as nk1 antagonists
NO20091741L (no)	2009-05-29	Pyrazolinforbindelser som mineralkortikoidreceptorantagonister
NO331174B1 (no)	2011-10-24	Substituerte 1-piperidin-4-yl-4-pyrrolidin-3-yl-piperazinderivater og deres anvendelse som neurokininantagonister
ATE225349T1 (de)	2002-10-15	Crf rezeptor-antagonisten und darauf bezogene methoden
MXPA05010760A (es)	2005-12-12	Derivados de acido 2-(8,9-dioxo-2,6-diazabiciclo[5.2.0]non-1(7)-en-2-il)alquil fosfonico y su uso como antagonistas de receptor de n-metil-d-aspartato (nmda).
TW200621753A (en)	2006-07-01	Pyrimidinylimidazoles and methods of making and using the same
NO20071319L (no)	2007-05-29	Fremgangsmate for fremstilling av isotiazolderivater.
MX2008001606A (es)	2008-04-14	Piperazinas substituidas como antagonistas de receptor de glutamato metabotropico.
TW200633984A (en)	2006-10-01	Amide compounds and activators of thrombopoietin receptor
MX2007007152A (es)	2007-08-14	Antagonista de naurocinina-1 con anillo en puente.
NO20080669L (no)	2008-05-15	Acetylenpiperaziner som metabotrofiske glutamatreseptorantagonister
NO20035148D0 (no)	2003-11-19	Tri- og tetra-aza-acenaftylenderivater som CRF- reseptorantagonister
TW200514785A (en)	2005-05-01	Hexa- and octahydro-pyrido[1,2-a]pyrazine derivatives with NK1 antagonistic activity
DE60100811D1 (de)	2003-10-23	Crf rezeptor-antagonisten und darauf bezogene methoden
TW200633997A (en)	2006-10-01	Substituted heterocyclic compounds and thrombopoietin receptor activators

Legal Events

Date	Code	Title	Description
2012-07-23	FC2A	Withdrawal, rejection or dismissal of laid open patent application