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NO20055078L - Hoyrene baser av 3,3-difenylpropylamin -monoestere - Google Patents

Hoyrene baser av 3,3-difenylpropylamin -monoestere

Info

Publication number
NO20055078L
NO20055078L NO20055078A NO20055078A NO20055078L NO 20055078 L NO20055078 L NO 20055078L NO 20055078 A NO20055078 A NO 20055078A NO 20055078 A NO20055078 A NO 20055078A NO 20055078 L NO20055078 L NO 20055078L
Authority
NO
Norway
Prior art keywords
compounds
hoyrene
bases
deuterium
disclosed
Prior art date
Application number
NO20055078A
Other languages
English (en)
Inventor
Hans-Michael Wolff
Claus Meese
Armin Breitenbach
Roland Drews
Original Assignee
Sanol Arznei Schwarz Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanol Arznei Schwarz Gmbh filed Critical Sanol Arznei Schwarz Gmbh
Publication of NO20055078L publication Critical patent/NO20055078L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

Det er beskrevet forbindelser med generell formel (I), hvori A er deuterium eller hydrogen, R står for en gruppe valgt fra C1-6-alkyl, C3-10-cykloalkyl eller fenyl, som i hvert tilfelle kan være substituert med C1-3-alkoksy, fluor, klor, brom, jod, nitro, amino, hydroksy, okso, merkapto eller deuterium, og hvorved det med "*" (stjerne) merkede C-atomet kan foreligge i (R)-konfigurasjon, i (S)-konfigurasjon eller som blanding derav, kjennetegnet ved at den nevnte forbindelsen foreligger som fri base med en renhetsgrad på over 97 vekt-%. Videre er det beskrevet en fremgangsmåte for fremstilling av de høvrene forbindelsene med generell formel (I) samt anvendelse av de høvrene forbindelsene for fremstilling av legemidler. Formel (I):
NO20055078A 2003-04-08 2005-10-31 Hoyrene baser av 3,3-difenylpropylamin -monoestere NO20055078L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10315917A DE10315917A1 (de) 2003-04-08 2003-04-08 Hochreine Basen von 3,3-Diphenylpropylaminmonoestern
PCT/EP2004/003567 WO2004089872A1 (de) 2003-04-08 2004-04-03 Hochreine basen von 3,3-diphenylpropylaminmonoestern

Publications (1)

Publication Number Publication Date
NO20055078L true NO20055078L (no) 2005-10-31

Family

ID=33154113

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20055078A NO20055078L (no) 2003-04-08 2005-10-31 Hoyrene baser av 3,3-difenylpropylamin -monoestere

Country Status (16)

Country Link
US (2) US20060014832A1 (no)
EP (1) EP1613584B1 (no)
JP (2) JP4651035B2 (no)
KR (1) KR100912451B1 (no)
CN (1) CN100475775C (no)
AU (1) AU2004228163B2 (no)
BR (1) BRPI0406221A (no)
CA (1) CA2505848A1 (no)
DE (2) DE10315917A1 (no)
ES (1) ES2297409T3 (no)
MX (1) MXPA05003562A (no)
NO (1) NO20055078L (no)
RU (1) RU2394019C2 (no)
UA (1) UA81803C2 (no)
WO (1) WO2004089872A1 (no)
ZA (1) ZA200502679B (no)

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IT1392082B1 (it) * 2008-12-10 2012-02-09 Chemi Spa Nuove forme solide della fesoterodina fumarato
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EP2459520A1 (en) 2009-09-03 2012-06-06 Teva Gyógyszergyár Zártköruen Muködo Részvénytársaság Crystalline forms of fesoterodine fumarate and fesoterodine base
EP2316432A1 (de) * 2009-10-30 2011-05-04 ratiopharm GmbH Zusammensetzung enthaltend Fesoterodin und Ballaststoffe
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Also Published As

Publication number Publication date
JP2010215643A (ja) 2010-09-30
EP1613584A1 (de) 2006-01-11
US7989654B2 (en) 2011-08-02
MXPA05003562A (es) 2005-06-03
UA81803C2 (en) 2008-02-11
US20060014832A1 (en) 2006-01-19
AU2004228163B2 (en) 2007-06-07
BRPI0406221A (pt) 2005-08-09
JP2006522758A (ja) 2006-10-05
ES2297409T3 (es) 2008-05-01
DE502004005560D1 (de) 2008-01-03
EP1613584B1 (de) 2007-11-21
HK1087399A1 (en) 2006-10-13
AU2004228163A1 (en) 2004-10-21
CA2505848A1 (en) 2004-10-21
KR20060006012A (ko) 2006-01-18
JP4651035B2 (ja) 2011-03-16
KR100912451B1 (ko) 2009-08-14
CN1802345A (zh) 2006-07-12
US20090012159A1 (en) 2009-01-08
RU2394019C2 (ru) 2010-07-10
ZA200502679B (en) 2006-04-26
RU2005134170A (ru) 2006-07-27
CN100475775C (zh) 2009-04-08
WO2004089872A1 (de) 2004-10-21
DE10315917A1 (de) 2004-11-18

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