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NO20053846L - Fremgangsmate for a modifisere legemiddel-krystalldannelse - Google Patents

Fremgangsmate for a modifisere legemiddel-krystalldannelse

Info

Publication number
NO20053846L
NO20053846L NO20053846A NO20053846A NO20053846L NO 20053846 L NO20053846 L NO 20053846L NO 20053846 A NO20053846 A NO 20053846A NO 20053846 A NO20053846 A NO 20053846A NO 20053846 L NO20053846 L NO 20053846L
Authority
NO
Norway
Prior art keywords
crystal formation
drug crystal
modifying drug
modifying
crystals
Prior art date
Application number
NO20053846A
Other languages
English (en)
Inventor
Sabine Pfeffer
Dierk Wieckhusen
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9951448&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20053846(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20053846L publication Critical patent/NO20053846L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Furan Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Det er beskrevet en fremgangsmåte for å modifisere krystalltilstanden av aciculære legemiddelstoffer, krystaller oppnådd ved en slik fremgangsmåte og spesielle krystallformer eller modifikasjoner av mycofenolsyre eller mycofenolatnatrium, så vel som farmasøytiske preparater omfattende krystallene, fremgangsmåter for behandling og anvendelse derav.
NO20053846A 2003-01-20 2005-08-16 Fremgangsmate for a modifisere legemiddel-krystalldannelse NO20053846L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0301259.8A GB0301259D0 (en) 2003-01-20 2003-01-20 Organic compounds
PCT/EP2004/000354 WO2004064806A2 (en) 2003-01-20 2004-01-19 Process for modifying drug crystal formation

Publications (1)

Publication Number Publication Date
NO20053846L true NO20053846L (no) 2005-08-16

Family

ID=9951448

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20053846A NO20053846L (no) 2003-01-20 2005-08-16 Fremgangsmate for a modifisere legemiddel-krystalldannelse

Country Status (31)

Country Link
US (3) US20060122265A1 (no)
EP (2) EP2308471A1 (no)
JP (1) JP4549976B2 (no)
KR (5) KR100855149B1 (no)
CN (2) CN101333201A (no)
AR (2) AR043343A1 (no)
AT (1) ATE546132T1 (no)
AU (1) AU2004206731B2 (no)
BR (1) BRPI0406827A (no)
CA (2) CA2706900A1 (no)
CL (1) CL2004000073A1 (no)
CO (1) CO5580738A2 (no)
CY (1) CY1112772T1 (no)
DK (1) DK1592401T3 (no)
EC (1) ECSP055918A (no)
ES (1) ES2382035T3 (no)
GB (1) GB0301259D0 (no)
IL (1) IL169484A (no)
MX (1) MXPA05007691A (no)
MY (1) MY148297A (no)
NO (1) NO20053846L (no)
NZ (1) NZ541073A (no)
PE (2) PE20040826A1 (no)
PL (2) PL376525A1 (no)
PT (1) PT1592401E (no)
RU (1) RU2388757C2 (no)
SG (1) SG155046A1 (no)
SI (1) SI1592401T1 (no)
TW (1) TWI325785B (no)
WO (1) WO2004064806A2 (no)
ZA (1) ZA200504442B (no)

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GB0124953D0 (en) 2001-10-17 2001-12-05 Novartis Ag Organic Compounds
GB0301259D0 (en) 2003-01-20 2003-02-19 Novartis Ag Organic compounds
AR045957A1 (es) * 2003-10-03 2005-11-16 Novartis Ag Composicion farmaceutica y combinacion
WO2005105768A2 (en) 2004-04-26 2005-11-10 Teva Gyógyszergyár Zàrtköruen Muködo Rèszvènytàrsasàg Process for preparation of mycophenolic acid and ester derivatives thereof
US20050250773A1 (en) 2004-04-27 2005-11-10 Sandor Molnar Process for preparation of mycophenolate mofetil and other esters of mycophenolic acid
DE602005020014D1 (de) 2004-07-20 2010-04-29 Teva Gyogyszergyar Zartkoeruen Kristallines mycophenolat-natrium
GB0419355D0 (en) * 2004-08-31 2004-09-29 Novartis Ag Organic compounds
US20080176937A1 (en) * 2007-01-23 2008-07-24 Apotex Fermentation Inc. Novel crystalline mycophenolate sodium polymorph and processes to manufacture same
JP5461565B2 (ja) * 2008-10-09 2014-04-02 アブディ イブラヒム イラク サナイ ベ ティカレット アノニム シルケティ 有機溶媒を使用したモキシフロキサシンの湿式造粒法
CN101756958B (zh) * 2008-11-10 2011-07-20 鲁南制药集团股份有限公司 一种治疗关节炎的药物组合物及其制备方法
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
JP5658751B2 (ja) * 2009-07-10 2015-01-28 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプＪａｎｓｓｅｎ Ｐｈａｒｍａｃｅｕｔｉｃａ Ｎａａｍｌｏｚｅ Ｖｅｎｎｏｏｔｓｃｈａｐ １−（β−Ｄ−グルコピラノシル）−４−メチル−３−［５−（４−フルオロフェニル）−２−チエニルメチル］ベンゼンのための結晶化方法
EP2488173A1 (en) * 2009-10-13 2012-08-22 Teva Pharmaceutical Industries Ltd. Delayed release compositions
EP4148045A1 (en) 2010-01-27 2023-03-15 Arena Pharmaceuticals, Inc. Intermediate compounds for the preparation of (r)-2-(7-(4-cyclopentyl-3- (trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b] indol-3-yl)acetic acid and salts thereof
SG185525A1 (en) 2010-05-11 2012-12-28 Janssen Pharmaceutica Nv Pharmaceutical formulations comprising 1 - (beta-d-glucopyranosyl) - 2 -thienylmethylbenzene derivatives as inhibitors of sglt
CN103880799A (zh) * 2010-11-16 2014-06-25 北京京卫信康医药科技发展有限公司 麦考酚酸钠的新晶型及其制备方法
CN103880800A (zh) * 2010-11-16 2014-06-25 北京京卫信康医药科技发展有限公司 麦考酚酸钠的新晶型及其制备方法
KR101913587B1 (ko) 2011-04-13 2018-10-31 얀센 파마슈티카 엔.브이. Sglt2의 억제제로서 유용한 화합물의 제조 방법
TWI582078B (zh) * 2013-01-23 2017-05-11 北京貝美拓新藥研發有限公司 抑制脯氨酸羥化酶活性的化合物的晶型及其應用
PL3310760T3 (pl) 2015-06-22 2023-03-06 Arena Pharmaceuticals, Inc. Krystaliczna sól L-argininy kwasu (R)-2-(7-(4-cyklopentylo-3-(trifluorometylo)benzyloksy)- 1,2,3,4-tetrahydrocyklo-penta[b]indol-3-ilo)octowego do zastosowania w zaburzeniach związanych z receptorem S1P1
US20170071970A1 (en) 2015-09-15 2017-03-16 Janssen Pharmaceutica Nv Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders
CN108368096B (zh) * 2015-12-21 2021-12-10 詹森药业有限公司 用于获得坎格列净半水合物晶体的结晶程序
AU2018222747A1 (en) 2017-02-16 2019-09-05 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of inflammatory bowel disease with extra-intestinal manifestations
CN110520124A (zh) 2017-02-16 2019-11-29 艾尼纳制药公司 用于治疗原发性胆汁性胆管炎的化合物和方法
CN108727317A (zh) * 2017-04-25 2018-11-02 鲁南制药集团股份有限公司 一种麦考酚酸的晶型物
CN108727318A (zh) * 2017-04-25 2018-11-02 鲁南制药集团股份有限公司 麦考酚酸的晶型物
CA3102136A1 (en) 2018-06-06 2019-12-12 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the s1p1 receptor
CN110922371B (zh) * 2019-12-27 2020-08-11 广东蓝宝制药有限公司 一种m2晶型麦考酚钠的制备方法
CN120172955A (zh) 2020-05-18 2025-06-20 诺华股份有限公司 Lnp023的结晶形式
US20250296904A1 (en) * 2022-05-31 2025-09-25 Honshu Chemical Industry Co., Ltd. Crystal of 4,4'-bis(1,1-bis(4-hydroxy-3-methylphenyl)ethyl)biphenyl and method for producing the same

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Also Published As

Publication number Publication date
US20060122265A1 (en) 2006-06-08
HK1084874A1 (en) 2006-08-11
PL393385A1 (pl) 2011-03-14
PL376525A1 (pl) 2006-01-09
RU2388757C2 (ru) 2010-05-10
ATE546132T1 (de) 2012-03-15
AU2004206731A8 (en) 2004-08-05
JP4549976B2 (ja) 2010-09-22
US20090209639A1 (en) 2009-08-20
KR20090115898A (ko) 2009-11-09
PL213192B1 (pl) 2013-01-31
GB0301259D0 (en) 2003-02-19
EP1592401A2 (en) 2005-11-09
IL169484A (en) 2016-03-31
CN1738605A (zh) 2006-02-22
KR100855149B1 (ko) 2008-08-28
NZ541073A (en) 2008-12-24
KR20090115821A (ko) 2009-11-06
ZA200504442B (en) 2006-02-22
MY148297A (en) 2013-03-29
IL169484A0 (en) 2007-07-04
AR103711A2 (es) 2017-05-31
PE20040826A1 (es) 2004-12-23
AU2004206731A1 (en) 2004-08-05
TW200505505A (en) 2005-02-16
TWI325785B (en) 2010-06-11
JP2006515016A (ja) 2006-05-18
ES2382035T3 (es) 2012-06-04
PT1592401E (pt) 2012-05-10
BRPI0406827A (pt) 2005-12-27
KR20050096940A (ko) 2005-10-06
US20110288313A1 (en) 2011-11-24
AU2004206731B2 (en) 2008-03-20
AR043343A1 (es) 2005-07-27
US8124795B2 (en) 2012-02-28
CA2509796A1 (en) 2004-08-05
CN100595199C (zh) 2010-03-24
ECSP055918A (es) 2005-11-22
WO2004064806A3 (en) 2004-10-28
CY1112772T1 (el) 2016-02-10
SG155046A1 (en) 2009-09-30
KR20100120321A (ko) 2010-11-15
CN101333201A (zh) 2008-12-31
CA2706900A1 (en) 2004-08-05
DK1592401T3 (da) 2012-05-21
US8008511B2 (en) 2011-08-30
KR101129105B1 (ko) 2012-04-12
EP1592401B1 (en) 2012-02-22
MXPA05007691A (es) 2005-09-30
CL2004000073A1 (es) 2005-01-14
PE20110276A1 (es) 2011-05-27
RU2005126328A (ru) 2006-07-27
SI1592401T1 (sl) 2012-05-31
KR20070087181A (ko) 2007-08-27
WO2004064806A2 (en) 2004-08-05
CA2509796C (en) 2010-09-14
CO5580738A2 (es) 2005-11-30
EP2308471A1 (en) 2011-04-13

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