NO20052909D0 - Tetracyclic 3-substituted indoles having serotonin receptor affinity. - Google Patents

Tetracyclic 3-substituted indoles having serotonin receptor affinity.

Info

Publication number: NO20052909D0
Authority: NO; Norway
Prior art keywords: tetracyclic; serotonin receptor; receptor affinity; substituted indoles; indoles
Prior art date: 2002-12-18

Application number

NO20052909A

Other languages

English (en)

Other versions

NO20052909L (no

NO334030B1 (no

Inventor

Venkata Satya Niro Ramakrishna

Vikas Shreekrishna Shirsath

Rama Sastri Kambhampati

Venkata Satya Veerabhadra Rao

Venkateswarlu Jasti

Original Assignee

Suven Life Sciences Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-18

Filing date

2005-06-15

Publication date

2005-06-15

2005-06-15 Application filed by Suven Life Sciences Ltd filed Critical Suven Life Sciences Ltd

2005-06-15 Publication of NO20052909D0 publication Critical patent/NO20052909D0/no

2005-09-12 Publication of NO20052909L publication Critical patent/NO20052909L/no

2013-11-18 Publication of NO334030B1 publication Critical patent/NO334030B1/no

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Ophthalmology & Optometry (AREA)
Psychology (AREA)
Epidemiology (AREA)
Optics & Photonics (AREA)
Physics & Mathematics (AREA)
Hospice & Palliative Care (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Diabetes (AREA)
Child & Adolescent Psychology (AREA)
Obesity (AREA)
Otolaryngology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Addiction (AREA)

NO20052909A 2002-12-18 2005-06-15 Tetrasykliske, 3-substituerte indoler samt deres fremstilling og anvendelse NO334030B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IN951MA2002		2002-12-18
PCT/IN2003/000393 WO2004055026A1 (en)	2002-12-18	2003-12-16	Tetracyclic 3-substituted indoles having serotonin receptor affinity

Publications (3)

Publication Number	Publication Date
NO20052909D0 true NO20052909D0 (no)	2005-06-15
NO20052909L NO20052909L (no)	2005-09-12
NO334030B1 NO334030B1 (no)	2013-11-18

Family

ID=40848934

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20052909A NO334030B1 (no)	2002-12-18	2005-06-15	Tetrasykliske, 3-substituerte indoler samt deres fremstilling og anvendelse

Country Status (19)

Country	Link
US (1)	US7781476B2 (no)
EP (1)	EP1581538B1 (no)
JP (1)	JP4571507B2 (no)
KR (1)	KR100739987B1 (no)
CN (1)	CN100378109C (no)
AT (1)	ATE355292T1 (no)
AU (1)	AU2003292510B2 (no)
BR (1)	BRPI0316895C1 (no)
CA (1)	CA2507923C (no)
DE (1)	DE60312226T2 (no)
DK (1)	DK1581538T3 (no)
EA (1)	EA009367B1 (no)
MX (1)	MXPA05005808A (no)
NO (1)	NO334030B1 (no)
NZ (1)	NZ540841A (no)
PT (1)	PT1581538E (no)
SI (1)	SI1581538T1 (no)
WO (1)	WO2004055026A1 (no)
ZA (1)	ZA200504042B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2005005439A1 (en) *	2003-07-09	2005-01-20	Suven Life Sciences Limited	Benzothiazino indoles
DK1704154T3 (da)	2004-01-02	2009-08-31	Suven Life Sciences Ltd	Nye indeno(2,1-A)indener og isoindol(2,1-A)indoler
ES2323535T3 (es) *	2005-03-08	2009-07-20	Suven Life Sciences Limited	Procedimiento para preparar benzotiazinoindoles sustituidos.
CA2618636C (en)	2005-08-12	2011-01-18	Suven Life Sciences Limited	Aminoaryl sulphonamide derivatives as functional 5-ht6 ligands
WO2007020654A1 (en)	2005-08-16	2007-02-22	Suven Life Sciences	An improved process for the preparation of losartan
MX2009006077A (es)	2007-01-08	2009-06-17	Suven Life Sciences Ltd	Compuestos de 5-(heterociclil)alquil-n-(arilsulfonil)indol y su uso como ligandos de la 5-hidroxitriptamina6.
JP5139512B2 (ja)	2007-05-03	2013-02-06	スベンライフサイエンシズリミティド	アミノアルコキシアリールスルホンアミド化合物及び５−ｈｔ６リガンドとしてのその使用
WO2008144263A1 (en) *	2007-05-18	2008-11-27	The Ohio State University Research Foundation	Potent indole-3-carbinol-derived antitumor agents
NZ585374A (en) *	2007-10-26	2011-09-30	Suven Life Sciences Ltd	Amino arylsulfonamide compounds for treating disorders related to 5-HT6 receptor functions
WO2010032257A1 (en)	2008-09-17	2010-03-25	Suven Life Sciences Limited	Aryl indolyl sulfonamide compounds and their use as 5-ht6 ligands
ES2424036T3 (es)	2008-09-17	2013-09-26	Suven Life Sciences Limited	Compuestos de amina de arilsulfonamida y su uso como ligandos de 5-HT6
US8153680B2 (en)	2009-08-25	2012-04-10	The Ohio State University Research Foundation	Alkyl indole-3-carbinol-derived antitumor agents
WO2013151982A1 (en)	2012-04-03	2013-10-10	Arena Pharmaceuticals, Inc.	Methods and compounds useful in treating pruritus, and methods for identifying such compounds
DK3077375T3 (en) *	2013-12-02	2017-09-11	Suven Life Sciences Ltd	PROCEDURE FOR LARGE SCALE PREPARATION OF 1 - [(2-BROMPHENYL) SULPHONYL] -5-METHOXY-3 - [(4-METHYL-1-PIPERAZINYL) METHYL] -1H-INDOL-DIMESYLATE-MONOHYDRATE
JP6629322B2 (ja)	2014-08-16	2020-01-15	スヴェン・ライフ・サイエンシズ・リミテッド	１−［（２−ブロモフェニル）スルフォニル］−５−メトキシ−３−［（４−メチル−１−ピペラジニル）メチル］−１ｈ−インドールジメシレート一水和物の活性代謝産物及びその活性代謝産物のジメシレート二水和物の塩
CA3023828C (en) *	2016-05-18	2019-08-27	Suven Life Sciences Limited	Combination of pure 5-ht6 receptor antagonists with nmda receptor antagonist
SI3484467T1 (sl) *	2016-05-18	2020-10-30	Suven Life Sciences Limited	Kombinacija čistih 5-HT receptor antagonistov z inhibitorji acetilholinesteraze
SI3518905T1 (sl) *	2016-10-03	2021-11-30	Suven Life Sciences Limited	Farmacevtski sestavki 5-HT6 antagonista
IL271694B2 (en) *	2017-07-03	2025-01-01	Suven Life Sciences Ltd	New uses of a pure 5-HT6 receptor antagonist – the compound 1-[(2-bromophenyl)sulfonyl]-5-methoxy-3-[(4-methyl-1-piperazinyl)methyl]-1-hydrogen-indole or its pharmaceutically acceptable salts

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3489429A (en) *	1967-12-18	1970-01-13	American Home Prod	1-loweralkanoyl-3-(2-substituted ethyl)indoles
ZA815541B (en)	1980-08-12	1983-03-30	Glaxo Group Ltd	Heterocyclic compounds
GB8600397D0 (en)	1986-01-08	1986-02-12	Glaxo Group Ltd	Chemical compounds
GB8719167D0 (en)	1987-08-13	1987-09-23	Glaxo Group Ltd	Chemical compounds
GB8724912D0 (en)	1987-10-23	1987-11-25	Wellcome Found	Indole derivatives
GB8819024D0 (en)	1988-08-10	1988-09-14	Glaxo Group Ltd	Chemical compounds
IL96891A0 (en)	1990-01-17	1992-03-29	Merck Sharp & Dohme	Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them
CA2042295A1 (fr)	1990-05-15	1991-11-16	Jacques Chauveau	Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
MC2210A1 (fr)	1990-06-07	1992-11-26	Wellcome Found	Composes heterocycliques therapeutiques,leur utilisation et procede pour les preparer
SK278998B6 (sk)	1991-02-01	1998-05-06	Merck Sharp & Dohme Limited	Deriváty imidazolu, triazolu a tetrazolu, spôsob i
GB9113802D0 (en)	1991-06-26	1991-08-14	Smithkline Beecham Plc	Medicaments
GB9210400D0 (en)	1992-05-15	1992-07-01	Merck Sharp & Dohme	Therapeutic agents
KR940007001A (ko)	1992-09-16	1994-04-26	최승주	새로운 n-신나모일-2-메틸-5-메톡시-3-인돌 아세트산 에스테르, 그 제조방법 및 이를 함유하는 약학적 제제
FR2737220B1 (fr)	1995-07-24	1997-09-26	Adir	Sequences nucleiques codant pour des recepteurs de la melatonine et leurs applications
JP2000026471A (ja) *	1998-07-10	2000-01-25	Nippon Soda Co Ltd	１１−ホルミル−インドロ［１，２−ｂ］［１，２］ベンズイソチアゾールおよび農園芸用殺菌剤
GB9820113D0 (en) *	1998-09-15	1998-11-11	Merck Sharp & Dohme	Therapeutic agents
US6403808B1 (en)	1999-12-10	2002-06-11	Virginia Commonwealth University	Selective 5-HT6 receptor ligands
WO2000034242A1 (en) *	1998-12-11	2000-06-15	Virginia Commonwealth University	Selective 5-ht6 receptor ligands
IL130169A (en)	1999-05-27	2006-08-20	Neurim Pharma 1991	Indole derivatives, and pharmaceutical preparations, skin protection preparations, and cosmetics containing them
FR2799757B1 (fr)	1999-10-15	2001-12-14	Adir	Nouveaux derives polycycliques azaindoliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN1317276C (zh) *	2000-09-29	2007-05-23	中国科学院上海药物研究所	一类吲哚基哌啶类化合物及其制备方法和用途
WO2002042292A2 (en) *	2000-11-20	2002-05-30	Scios Inc.	Indol derivative and their use as inhibitors of p38 kinase
FR2821843B1 (fr)	2001-03-12	2003-05-09	Servier Lab	Nouveaux derives d'isoindoloindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2003066056A1 (en)	2002-02-05	2003-08-14	Glaxo Group Limited	Method of promoting neuronal growth
US7297711B2 (en) *	2002-06-21	2007-11-20	Suven Life Sciences Limited	Arylalkyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
EP1523486B1 (en) *	2002-06-21	2007-11-07	Suven Life Sciences Limited	Tetracyclic arylsulfonyl indoles having serotonin receptor affinity
BRPI0315958B8 (pt) *	2002-11-28	2021-05-25	Suven Life Sciences Ltd	composto, composição farmacêutica, processo para a preparação de um composto, novos intermediários e uso do composto

2003
- 2003-12-16 SI SI200330795T patent/SI1581538T1/sl unknown
- 2003-12-16 AT AT03768092T patent/ATE355292T1/de active
- 2003-12-16 JP JP2004560176A patent/JP4571507B2/ja not_active Expired - Fee Related
- 2003-12-16 AU AU2003292510A patent/AU2003292510B2/en not_active Ceased
- 2003-12-16 EA EA200500994A patent/EA009367B1/ru not_active IP Right Cessation
- 2003-12-16 EP EP03768092A patent/EP1581538B1/en not_active Expired - Lifetime
- 2003-12-16 NZ NZ540841A patent/NZ540841A/en not_active IP Right Cessation
- 2003-12-16 KR KR1020057010266A patent/KR100739987B1/ko not_active Expired - Fee Related
- 2003-12-16 WO PCT/IN2003/000393 patent/WO2004055026A1/en not_active Ceased
- 2003-12-16 CA CA002507923A patent/CA2507923C/en not_active Expired - Fee Related
- 2003-12-16 DK DK03768092T patent/DK1581538T3/da active
- 2003-12-16 DE DE60312226T patent/DE60312226T2/de not_active Expired - Lifetime
- 2003-12-16 PT PT03768092T patent/PT1581538E/pt unknown
- 2003-12-16 MX MXPA05005808A patent/MXPA05005808A/es active IP Right Grant
- 2003-12-16 US US10/539,262 patent/US7781476B2/en not_active Expired - Fee Related
- 2003-12-16 CN CNB2003801070251A patent/CN100378109C/zh not_active Expired - Fee Related
- 2003-12-16 BR BRPI0316895A patent/BRPI0316895C1/pt not_active IP Right Cessation
2005
- 2005-06-15 NO NO20052909A patent/NO334030B1/no not_active IP Right Cessation
2006
- 2006-01-26 ZA ZA200504042A patent/ZA200504042B/en unknown

Also Published As

Publication number	Publication date
CN1729197A (zh)	2006-02-01
EP1581538B1 (en)	2007-02-28
DE60312226D1 (de)	2007-04-12
CA2507923C (en)	2010-02-02
JP4571507B2 (ja)	2010-10-27
CA2507923A1 (en)	2004-07-01
KR20050084185A (ko)	2005-08-26
KR100739987B1 (ko)	2007-07-16
HK1083840A1 (en)	2006-07-14
EA009367B1 (ru)	2007-12-28
JP2006515843A (ja)	2006-06-08
SI1581538T1 (sl)	2007-08-31
BR0316895A (pt)	2005-10-25
ATE355292T1 (de)	2006-03-15
BRPI0316895C1 (pt)	2021-05-25
DK1581538T3 (da)	2007-06-25
WO2004055026A1 (en)	2004-07-01
WO2004055026A8 (en)	2005-06-23
BRPI0316895B8 (pt)	2019-09-03
DE60312226T2 (de)	2007-11-15
CN100378109C (zh)	2008-04-02
MXPA05005808A (es)	2005-09-08
EP1581538A1 (en)	2005-10-05
US7781476B2 (en)	2010-08-24
AU2003292510B2 (en)	2009-04-23
AU2003292510A1 (en)	2004-07-09
ZA200504042B (en)	2006-01-26
PT1581538E (pt)	2007-05-31
NZ540841A (en)	2008-08-29
NO20052909L (no)	2005-09-12
EA200500994A1 (ru)	2006-02-24
US20070142398A1 (en)	2007-06-21
NO334030B1 (no)	2013-11-18
BRPI0316895B1 (pt)	2018-07-24

Publication	Publication Date	Title
NO20052909L (no)	2005-09-12	Tetracyclic 3-substituted indoles having serotonin receptor affinity.
NO20035359D0 (no)	2003-12-02	Nye indolderivater med 5-HT6-reseptoraffinitet
ATE344030T1 (de)	2006-11-15	4-piperazinylbenzolsulfonyl-indole mit 5-ht6 rezeptor-affinität
ATE392206T1 (de)	2008-05-15	Indolderivate als beta-2 agonisten
DK1218352T3 (da)	2004-06-28	Benzimidazolonderivater med affinitet for både serotonin- og dopamin-receptorer
ATE340792T1 (de)	2006-10-15	Substituierte indole als alpha-1 agonisten
DK1513832T3 (da)	2014-05-26	Indol, azaindol og relaterede heterocykliske 4-alkenylpiperidinamider
ATE430730T1 (de)	2009-05-15	Phenyl-substituierte indole als h3 histaminrezeptorantagonisten
ATE401307T1 (de)	2008-08-15	N-arylsulfonyl-2-substituierte indole mit affinität zum serotonin rezeptor, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
ZA200800512B (en)	2009-06-24	Substituted tetrahydro-1H-pyrido[4,3,B]indoles as serotonin receptor agonists and antagonists
MXPA03003039A (es)	2003-10-15	Derivados de indola y bencimidazola como moduladores del receptor crf.
ATE374184T1 (de)	2007-10-15	Substituierte indol-mannichbasen
AU2003236512A8 (en)	2004-01-06	Indole, azaindole and related heterocyclic sulfonylureido piperazine derivatives
NO20026168D0 (no)	2002-12-20	3-azabicyklo(3.1.0)heksan derivater med opioid reseptor affinitet
ATE399776T1 (de)	2008-07-15	Pyrrol-2,5-dithionderivate als modulatoren des liver-x-rezeptors
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