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NO20043951L - 3-cyklyl-5-(nitrogenholdig 5-leddet ring) metyl-oksazolidinon-derivater og deres anvendelse som antibakterielle midler - Google Patents

3-cyklyl-5-(nitrogenholdig 5-leddet ring) metyl-oksazolidinon-derivater og deres anvendelse som antibakterielle midler

Info

Publication number
NO20043951L
NO20043951L NO20043951A NO20043951A NO20043951L NO 20043951 L NO20043951 L NO 20043951L NO 20043951 A NO20043951 A NO 20043951A NO 20043951 A NO20043951 A NO 20043951A NO 20043951 L NO20043951 L NO 20043951L
Authority
NO
Norway
Prior art keywords
antibacterial agents
formula
cyclyl
nitrogen
membered ring
Prior art date
Application number
NO20043951A
Other languages
English (en)
Other versions
NO20043951D0 (no
Inventor
Michael Barry Gravestock
Neil James Hales
Folkert Reck
Fei Zhou
Paul Robert Fleming
Daniel Robert Carcanague
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20043951D0 publication Critical patent/NO20043951D0/no
Publication of NO20043951L publication Critical patent/NO20043951L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Forbindelser av formel (I), eller et farmasøytisk akseptabelt salt, eller en in vivo-hydrolyserbar ester derav,. hvor -N-HET er f.eks. formel (Ic) eller (If),hvor RI er f.eks. halogen eller en (l-4C)alkylgruppe som er substituert med en substi-tuent valgt fra f.eks. hydroksy, (l-4C)alkoksy, amino, cyano eller azido; Q er valgt fra f.eks. Ql, formel Qlhvor R2 og R3 er uavhengig hydrogen eller fluor; T er valgt fra en rekke grupper, f.eks. formel (TC12b). hvor m er 0,1 eller 2; er nyttige som antibakterielle midler; og fremgangsmåter for de-res fremstilling og farmasøytiske preparater som inneholder dem.
NO20043951A 2002-02-28 2004-09-21 3-cyklyl-5-(nitrogenholdig 5-leddet ring) metyl-oksazolidinon-derivater og deres anvendelse som antibakterielle midler NO20043951L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36068802P 2002-02-28 2002-02-28
PCT/GB2003/000791 WO2003072576A2 (en) 2002-02-28 2003-02-25 Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
NO20043951D0 NO20043951D0 (no) 2004-09-21
NO20043951L true NO20043951L (no) 2004-11-11

Family

ID=27766238

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20043951A NO20043951L (no) 2002-02-28 2004-09-21 3-cyklyl-5-(nitrogenholdig 5-leddet ring) metyl-oksazolidinon-derivater og deres anvendelse som antibakterielle midler

Country Status (20)

Country Link
US (1) US7199143B2 (no)
EP (1) EP1480975A2 (no)
JP (1) JP2005531504A (no)
KR (1) KR20040086465A (no)
CN (1) CN1653064A (no)
AR (1) AR039559A1 (no)
AU (1) AU2003209994A1 (no)
BR (1) BR0308018A (no)
CA (1) CA2477379A1 (no)
CO (1) CO5601010A2 (no)
IL (1) IL163643A0 (no)
IS (1) IS7424A (no)
MX (1) MXPA04008273A (no)
NO (1) NO20043951L (no)
NZ (1) NZ535591A (no)
PL (1) PL372090A1 (no)
RU (1) RU2004129278A (no)
TW (1) TW200403241A (no)
WO (1) WO2003072576A2 (no)
ZA (1) ZA200406684B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL160739A0 (en) 2001-09-11 2004-08-31 Astrazeneca Ab Oxazolidinone and/or isoxazoline as antibacterial agents
EP1443930A1 (en) 2001-10-25 2004-08-11 AstraZeneca AB Isoxazoline derivatives useful as antimicrobials
RU2004129276A (ru) * 2002-02-28 2005-06-10 Астразенека Аб (Se) Производные 3-циклического-5-(азотсодержащего 5-членного кольцевого) метил-оксазолидинона и их применение в качестве антибактериальных средств
AR043050A1 (es) * 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
AU2003285509A1 (en) * 2002-11-28 2004-06-18 Astrazeneca Ab Oxazolidinones as antibacterial agents
GB0306358D0 (en) 2003-03-20 2003-04-23 Astrazeneca Ab Chemical compounds
WO2005042523A1 (en) * 2003-11-03 2005-05-12 Il-Dong Pharm. Co., Ltd. A novel oxazolidinone derivative and manufacturing process thereof
KR100854211B1 (ko) 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
ATE449773T1 (de) 2005-06-29 2009-12-15 Pharmacia & Upjohn Co Llc Homomorpholinoxazolidinone als antibakterielle mittel
US8084477B2 (en) 2007-10-31 2011-12-27 Bristol-Myers Squibb Company Alpha-(N-sulfonamido)acetamide compound as an inhibitor of beta amyloid peptide production
KR101674146B1 (ko) 2008-10-10 2016-11-08 머크 샤프 앤드 돔 코포레이션 옥사졸리디논 및 이를 포함하는 조성물을 제조하는 방법
ES2734724T3 (es) 2009-02-03 2019-12-11 Merck Sharp & Dohme Forma cristalina de dihidrogenofosfato de (R)-3-(4-(2-(2-metiltetrazol-5-il)piridin-5-il)-3-fluorofenil)-5-hidroximetiloxazolidin-2-ona
US8580767B2 (en) 2009-05-28 2013-11-12 Trius Therapeutics, Inc. Oxazolidinone containing dimer compounds, compositions and methods to make and use
CN101792437B (zh) * 2010-03-10 2012-01-25 天津药物研究院 一类三氮唑的衍生物、其制备方法和用途

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1260948A (en) * 1984-12-05 1989-09-26 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents
MY115155A (en) 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
DE4332384A1 (de) * 1993-09-23 1995-03-30 Merck Patent Gmbh Adhäsionsrezeptor-Antagonisten III
GB9521508D0 (en) 1995-10-20 1995-12-20 Zeneca Ltd Chemical compounds
GB9601666D0 (en) 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9604301D0 (en) 1996-02-29 1996-05-01 Zeneca Ltd Chemical compounds
GB9609919D0 (en) 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
GB9614236D0 (en) 1996-07-06 1996-09-04 Zeneca Ltd Chemical compounds
GB9614238D0 (en) 1996-07-06 1996-09-04 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
AU8872198A (en) 1997-08-29 1999-03-22 Zeneca Limited Aminometyl oxooxazolidinyl benzene derivatives
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
GB9812019D0 (en) 1998-06-05 1998-07-29 Zeneca Ltd Chemical compounds
AU753988B2 (en) 1998-06-05 2002-10-31 Astrazeneca Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
GB9821938D0 (en) 1998-10-09 1998-12-02 Zeneca Ltd Chemical compounds
GB9928499D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical processes and intermediates
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
CN1395569A (zh) 2000-02-10 2003-02-05 法玛西雅厄普约翰美国公司 含有哌嗪酰胺取代基的噁唑二酮硫代酰胺
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6277868B1 (en) * 2000-08-31 2001-08-21 Abbott Laboratories Oxazolidinone chemotherapeutic agents
JP3972575B2 (ja) 2000-11-02 2007-09-05 株式会社日立製作所 ドアシステム
GB0108764D0 (en) 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compounds
GB0108793D0 (en) 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compounds
JP2004531518A (ja) 2001-04-07 2004-10-14 アストラゼネカ アクチボラグ スルホンイミド基を含有する、抗生物質としてのオキサゾリジノン
GB0108794D0 (en) 2001-04-07 2001-05-30 Astrazeneca Ab Chemical compound
GB0113297D0 (en) 2001-06-01 2001-07-25 Astrazeneca Ab Chemical Process
GB0113299D0 (en) 2001-06-01 2001-07-25 Astrazeneca Ab Chemical process & intermediates
GB0113300D0 (en) 2001-06-01 2001-07-25 Astrazeneca Ab Purification process
GB0121490D0 (en) 2001-09-05 2001-10-24 Smithkline Beecham Plc Ciompounds
IL160739A0 (en) 2001-09-11 2004-08-31 Astrazeneca Ab Oxazolidinone and/or isoxazoline as antibacterial agents
GB2396350A (en) 2001-10-25 2004-06-23 Astrazeneca Ab Aryl substituted oxazolidinones with antibacterial activity
EP1443930A1 (en) 2001-10-25 2004-08-11 AstraZeneca AB Isoxazoline derivatives useful as antimicrobials
AU2003285509A1 (en) 2002-11-28 2004-06-18 Astrazeneca Ab Oxazolidinones as antibacterial agents
US20060116400A1 (en) 2002-11-28 2006-06-01 Astrazeneca Ab Oxazolidinone and/or isoxazoline derivatives as antibacterial agents
GB0227701D0 (en) 2002-11-28 2003-01-08 Astrazeneca Ab Chemical compounds
GB0229521D0 (en) 2002-12-19 2003-01-22 Astrazeneca Ab Chemical compounds
GB0229522D0 (en) 2002-12-19 2003-01-22 Astrazeneca Ab Chemical compounds
GB0229526D0 (en) 2002-12-19 2003-01-22 Astrazeneca Ab Chemical compounds
GB0229518D0 (en) 2002-12-19 2003-01-22 Astrazeneca Ab Chemical compounds
TW200500360A (en) 2003-03-01 2005-01-01 Astrazeneca Ab Hydroxymethyl compounds
GB0306357D0 (en) 2003-03-20 2003-04-23 Astrazeneca Ab Chemical compounds
GB0306358D0 (en) 2003-03-20 2003-04-23 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
CA2477379A1 (en) 2003-09-04
US20050182112A1 (en) 2005-08-18
WO2003072576A2 (en) 2003-09-04
RU2004129278A (ru) 2005-06-10
MXPA04008273A (es) 2004-11-10
EP1480975A2 (en) 2004-12-01
TW200403241A (en) 2004-03-01
IS7424A (is) 2004-08-26
AU2003209994A1 (en) 2003-09-09
BR0308018A (pt) 2005-01-04
NZ535591A (en) 2006-07-28
IL163643A0 (en) 2005-12-18
US7199143B2 (en) 2007-04-03
NO20043951D0 (no) 2004-09-21
KR20040086465A (ko) 2004-10-08
CN1653064A (zh) 2005-08-10
JP2005531504A (ja) 2005-10-20
AR039559A1 (es) 2005-02-23
ZA200406684B (en) 2005-09-21
PL372090A1 (en) 2005-07-11
CO5601010A2 (es) 2006-01-31
WO2003072576A3 (en) 2003-12-31

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