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NO20023038D0 - Nye azabicyklooktanderivater for behandling av kardialarytmier - Google Patents

Nye azabicyklooktanderivater for behandling av kardialarytmier

Info

Publication number
NO20023038D0
NO20023038D0 NO20023038A NO20023038A NO20023038D0 NO 20023038 D0 NO20023038 D0 NO 20023038D0 NO 20023038 A NO20023038 A NO 20023038A NO 20023038 A NO20023038 A NO 20023038A NO 20023038 D0 NO20023038 D0 NO 20023038D0
Authority
NO
Norway
Prior art keywords
treatment
new
cardiac arrhythmias
azabicyclooctane
derivatives
Prior art date
Application number
NO20023038A
Other languages
English (en)
Other versions
NO20023038L (no
Inventor
Magnus Bjoersne
Fritiof Ponten
Gert Strandlund
Peder Svensson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20023038D0 publication Critical patent/NO20023038D0/no
Publication of NO20023038L publication Critical patent/NO20023038L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/24Camphidines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20023038A 1999-12-23 2002-06-21 Nye azabicyklooktanderivater for anvendelse ved behandling av kardiale arytmier NO20023038L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9904765A SE9904765D0 (sv) 1999-12-23 1999-12-23 Pharmaceutically-useful compounds
PCT/SE2000/002604 WO2001047893A1 (en) 1999-12-23 2000-12-19 New azabicyclooctane derivatives useful in the treatment of cardiac arrhythmias

Publications (2)

Publication Number Publication Date
NO20023038D0 true NO20023038D0 (no) 2002-06-21
NO20023038L NO20023038L (no) 2002-08-22

Family

ID=20418291

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20023038A NO20023038L (no) 1999-12-23 2002-06-21 Nye azabicyklooktanderivater for anvendelse ved behandling av kardiale arytmier

Country Status (26)

Country Link
US (1) US6559162B2 (no)
EP (1) EP1244631A1 (no)
JP (1) JP2003519128A (no)
KR (1) KR20020063261A (no)
CN (1) CN1229350C (no)
AR (1) AR026925A1 (no)
AU (1) AU777069B2 (no)
BR (1) BR0016678A (no)
CA (1) CA2394097A1 (no)
CO (1) CO5261611A1 (no)
CZ (1) CZ20022174A3 (no)
EE (1) EE200200305A (no)
HU (1) HUP0301030A3 (no)
IL (1) IL150212A0 (no)
IS (1) IS6438A (no)
MX (1) MXPA02006249A (no)
MY (1) MY133785A (no)
NO (1) NO20023038L (no)
NZ (1) NZ519497A (no)
PL (1) PL357098A1 (no)
RU (1) RU2262505C2 (no)
SE (1) SE9904765D0 (no)
SK (1) SK8912002A3 (no)
UA (1) UA75057C2 (no)
WO (1) WO2001047893A1 (no)
ZA (1) ZA200204310B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9903759D0 (sv) * 1999-10-18 1999-10-18 Astra Ab Pharmaceutically active compounds
ES2275657T3 (es) * 2000-03-20 2007-06-16 MERCK SHARP & DOHME LTD. Derivados de bicicloalquilo puenteados sulfonamido sustituidos.
MXPA04000565A (es) * 2001-07-19 2005-06-17 Cv Therapeutics Inc Compuestos de piperazina sustituidos y su uso como inhibidores de oxidacion de acidos grasos.
US7001909B2 (en) * 2001-07-19 2006-02-21 Cv Therapeutics, Inc. Substituted heterocyclic compounds
MXPA05000434A (es) 2002-07-08 2005-04-19 Ranbaxy Lab Ltd Derivados de hexano [3.1.0] azabiciclo 3,6-disustituido utiles como antagonistas de receptor muscarinico.
US7056924B2 (en) * 2002-07-18 2006-06-06 Cv Therapeutics, Inc. Substituted heterocyclic compounds
US7488748B2 (en) * 2003-01-28 2009-02-10 Ranbaxy Laboratories Limited 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists
US7517905B2 (en) 2003-04-09 2009-04-14 Ranbaxy Laboratories Limited Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists
EP1626957A1 (en) 2003-04-11 2006-02-22 Ranbaxy Laboratories Limited Azabicyclo derivatives as muscarinic receptor antagonists
NZ544449A (en) * 2003-06-23 2008-10-31 Cv Therapeutics Inc Urea derivatives of piperazines and piperidines as fatty acid oxidation inhibitors
WO2006035303A1 (en) * 2004-09-29 2006-04-06 Ranbaxy Laboratories Limited Muscarinic receptor antagonists
JP4994772B2 (ja) * 2006-10-11 2012-08-08 日本曹達株式会社 ビスアミノールエーテル化合物を用いるピペリジン−4−オン誘導体の製造方法
JP4999061B2 (ja) * 2006-10-11 2012-08-15 日本曹達株式会社 ピペリジン−4−オン誘導体の製造方法
KR20100017687A (ko) * 2007-05-17 2010-02-16 코텍스 파마슈티칼스, 인크. 글루타메이트에 의한 시냅스 반응을 향상시키기 위한 이치환된 아미드 화합물
CN102311439B (zh) * 2010-07-02 2015-11-25 上海药明康德新药开发有限公司 1-取代-3,8-二氮杂双环[3.2.1]辛烷衍生物及制备方法
CN102452981B (zh) * 2010-11-03 2015-08-19 上海药明康德新药开发有限公司 1,3-二取代-3-氮杂双环[3.2.1]辛烷衍生物及制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2428792A1 (de) 1974-06-14 1976-01-02 Knoll Ag Neue antiarrhythmika
DE3112055A1 (de) 1981-03-27 1982-10-07 Basf Ag, 6700 Ludwigshafen Bispidinderivate, ihre herstellung und diese enthaltende arzneimittel
DE3234697A1 (de) 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
GB8516371D0 (en) * 1985-06-28 1985-07-31 Beecham Group Plc Compounds
PT88381B (pt) 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
DE3732094A1 (de) 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
US5070094A (en) * 1989-09-05 1991-12-03 G. D. Searle & Co. N-benzyltropaneamides
US5110933A (en) 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
US5084572A (en) * 1989-11-13 1992-01-28 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo [3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
FR2707986B1 (fr) * 1993-07-22 1996-02-23 Smithkline Beecham Labo Pharma Nouveaux composés, leur procédé de préparation et leur utilisation en tant que médicaments.
JP3235913B2 (ja) * 1993-07-30 2001-12-04 エーザイ株式会社 アミノ安息香酸誘導体
US5468858A (en) 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
DE4402931A1 (de) 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh Neue 3-Phenylsulfonyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel
EA002270B1 (ru) 1996-03-29 2002-02-28 Пфайзер Инк. Производные 6-фенилпиридил-2-амина
WO1998018788A1 (en) 1996-10-30 1998-05-07 Schering Corporation Piperazino derivatives as neurokinin antagonists
SE9704709D0 (sv) 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
HUP0202214A3 (en) 1999-04-09 2002-12-28 Astrazeneca Ab Adamantane derivatives, preparation and use thereof
SE9901875D0 (sv) 1999-05-25 1999-05-25 Astra Pharma Prod Novel compounds

Also Published As

Publication number Publication date
RU2262505C2 (ru) 2005-10-20
EP1244631A1 (en) 2002-10-02
WO2001047893A1 (en) 2001-07-05
AR026925A1 (es) 2003-03-05
US6559162B2 (en) 2003-05-06
AU2565901A (en) 2001-07-09
US20020137766A1 (en) 2002-09-26
PL357098A1 (en) 2004-07-12
BR0016678A (pt) 2002-10-15
EE200200305A (et) 2003-06-16
IS6438A (is) 2002-06-20
KR20020063261A (ko) 2002-08-01
IL150212A0 (en) 2002-12-01
CA2394097A1 (en) 2001-07-05
SK8912002A3 (en) 2003-02-04
UA75057C2 (en) 2006-03-15
HUP0301030A2 (hu) 2003-08-28
AU777069B2 (en) 2004-09-30
SE9904765D0 (sv) 1999-12-23
HUP0301030A3 (en) 2007-03-28
ZA200204310B (en) 2003-08-29
NZ519497A (en) 2004-02-27
CN1434802A (zh) 2003-08-06
RU2002114821A (ru) 2004-01-20
CN1229350C (zh) 2005-11-30
MY133785A (en) 2007-11-30
CO5261611A1 (es) 2003-03-31
CZ20022174A3 (cs) 2002-09-11
JP2003519128A (ja) 2003-06-17
MXPA02006249A (es) 2004-09-06
NO20023038L (no) 2002-08-22

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Legal Events

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