NO20022125D0 - Pyrrolderivater som inhibitorer for fosfodiesterase VII - Google Patents

Pyrrolderivater som inhibitorer for fosfodiesterase VII

Info

Publication number: NO20022125D0
Authority: NO; Norway
Prior art keywords: inhibitors; pyrrole derivatives; phosphodiesterase vii; phosphodiesterase; vii
Prior art date: 1999-11-04

Application number

NO20022125A

Other languages

English (en)

Other versions

NO20022125L (no

Inventor

Hans-Michael Eggenweiler

Rochus Jonas

Michael Wolf

Michael Gassen

Thomas Welge

Original Assignee

Merck Patent Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-11-04

Filing date

2002-05-03

Publication date

2002-05-03

2002-05-03 Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh

2002-05-03 Publication of NO20022125L publication Critical patent/NO20022125L/no

2002-05-03 Publication of NO20022125D0 publication Critical patent/NO20022125D0/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Physical Education & Sports Medicine (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Orthopedic Medicine & Surgery (AREA)
Neurosurgery (AREA)
Oncology (AREA)
Dermatology (AREA)
Hematology (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Transplantation (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Hospice & Palliative Care (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)

NO20022125A 1999-11-04 2002-05-03 Pyrrolderivater som inhibitorer for fosfodiesterase VII NO20022125D0 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19953025A DE19953025A1 (de)	1999-11-04	1999-11-04	Pyrrolderivate als Phosphodiesterase VII-Hemmer
PCT/EP2000/010526 WO2001032618A1 (de)	1999-11-04	2000-10-25	Pyrrolderivate als phosphodiesterase vii-hemmer

Publications (2)

Publication Number	Publication Date
NO20022125L NO20022125L (no)	2002-05-03
NO20022125D0 true NO20022125D0 (no)	2002-05-03

Family

ID=7927861

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20022125A NO20022125D0 (no)	1999-11-04	2002-05-03	Pyrrolderivater som inhibitorer for fosfodiesterase VII

Country Status (22)

Country	Link
US (1)	US6737436B1 (no)
EP (1)	EP1230215B1 (no)
JP (1)	JP2003513070A (no)
KR (1)	KR20020063173A (no)
CN (1)	CN1382122A (no)
AR (1)	AR026351A1 (no)
AT (1)	ATE339403T1 (no)
AU (1)	AU782477B2 (no)
BR (1)	BR0015334A (no)
CA (1)	CA2389709C (no)
CZ (1)	CZ20021440A3 (no)
DE (2)	DE19953025A1 (no)
ES (1)	ES2272331T3 (no)
HK (1)	HK1049831A1 (no)
HU (1)	HUP0203288A3 (no)
MX (1)	MXPA02004440A (no)
NO (1)	NO20022125D0 (no)
PL (1)	PL355099A1 (no)
RU (1)	RU2002113750A (no)
SK (1)	SK5952002A3 (no)
WO (1)	WO2001032618A1 (no)
ZA (1)	ZA200204433B (no)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6946481B1 (en) *	1994-08-19	2005-09-20	Abbott Laboratories	Endothelin antagonists
BR0207215A (pt)	2001-12-13	2004-02-10	Daiichi Suntory Pharma Co Ltd	Derivados de pirazolopiriminona tendo ação de inibição de pde7
DE10163991A1 (de) *	2001-12-24	2003-07-03	Merck Patent Gmbh	Pyrrolo-pyrimidine
DE10226420A1 (de) *	2002-06-13	2004-01-15	Eucro European Contract Research Gmbh & Co Kg	Verfahren zur Behandlung der Artherosklerose
JP2006219373A (ja) *	2003-06-13	2006-08-24	Daiichi Asubio Pharma Co Ltd	Ｐｄｅ７阻害作用を有するピリジニルピラゾロピリミジノン誘導体
JP2006219374A (ja)	2003-06-13	2006-08-24	Daiichi Asubio Pharma Co Ltd	Ｐｄｅ７阻害作用を有するイミダゾトリアジノン誘導体
CN102827082B (zh) *	2004-07-01	2015-01-07	第一三共株式会社	具有pde7抑制活性的噻吩并吡唑衍生物
CA2620333A1 (en)	2005-08-26	2007-03-01	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation
EP2258359A3 (en)	2005-08-26	2011-04-06	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation with sabcomelin
AU2006304787A1 (en)	2005-10-21	2007-04-26	Braincells, Inc.	Modulation of neurogenesis by PDE inhibition
EP2314289A1 (en)	2005-10-31	2011-04-27	Braincells, Inc.	Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
JP2009536667A (ja)	2006-05-09	2009-10-15	ブレインセルス，インコーポレイティド	５ｈｔ受容体介在性の神経新生
EP2021000A2 (en)	2006-05-09	2009-02-11	Braincells, Inc.	Neurogenesis by modulating angiotensin
MX2009002496A (es)	2006-09-08	2009-07-10	Braincells Inc	Combinaciones que contienen un derivado de 4-acilaminopiridina.
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
US8637528B2 (en)	2007-03-27	2014-01-28	Omeros Corporation	Use of PDE7 inhibitors for the treatment of movement disorders
NZ580413A (en) *	2007-03-27	2012-11-30	Omeros Corp	The use of pde7 inhibitors for the treatment of movement disorders
US20100216805A1 (en)	2009-02-25	2010-08-26	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
NZ610925A (en)	2010-11-08	2015-10-30	Omeros Corp	Treatment of addiction and impulse-control disorders using pde7 inhibitors
US9220715B2 (en)	2010-11-08	2015-12-29	Omeros Corporation	Treatment of addiction and impulse-control disorders using PDE7 inhibitors
WO2013106547A1 (en)	2012-01-10	2013-07-18	President And Fellows Of Harvard College	Beta-cell replication promoting compounds and methods of their use
EP3652180B1 (en)	2017-07-12	2023-11-29	Dart NeuroScience, LLC	Substituted benzoxazole and benzofuran compounds as pde7 inhibitors
IL318817A (en)	2022-08-18	2025-04-01	Mitodicure Gmbh	Use of a therapeutic agent with PHOSPHODIESTERASE-7 inhibitory activity for the treatment and prevention of diseases associated with chronic fatigue, exhaustion and/or exercise intolerance

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE154827C (no)
DD154827A1 (de) *	1980-11-28	1982-04-21	Karl Gewald	Verfahren zur herstellung von azofarbstoffen aus substituierten 3-aminopyrrolen
US5935990A (en) *	1996-12-10	1999-08-10	G.D. Searle & Co.	Substituted pyrrolyl compounds for the treatment of inflammation

1999
- 1999-11-04 DE DE19953025A patent/DE19953025A1/de not_active Withdrawn
2000
- 2000-10-25 DE DE50013473T patent/DE50013473D1/de not_active Expired - Lifetime
- 2000-10-25 AU AU13873/01A patent/AU782477B2/en not_active Ceased
- 2000-10-25 CZ CZ20021440A patent/CZ20021440A3/cs unknown
- 2000-10-25 HU HU0203288A patent/HUP0203288A3/hu unknown
- 2000-10-25 WO PCT/EP2000/010526 patent/WO2001032618A1/de not_active Ceased
- 2000-10-25 BR BR0015334-6A patent/BR0015334A/pt not_active Application Discontinuation
- 2000-10-25 US US10/129,261 patent/US6737436B1/en not_active Expired - Fee Related
- 2000-10-25 JP JP2001534770A patent/JP2003513070A/ja active Pending
- 2000-10-25 KR KR1020027005646A patent/KR20020063173A/ko not_active Withdrawn
- 2000-10-25 CN CN00814828A patent/CN1382122A/zh active Pending
- 2000-10-25 CA CA002389709A patent/CA2389709C/en not_active Expired - Fee Related
- 2000-10-25 EP EP00975917A patent/EP1230215B1/de not_active Expired - Lifetime
- 2000-10-25 ES ES00975917T patent/ES2272331T3/es not_active Expired - Lifetime
- 2000-10-25 RU RU2002113750/15A patent/RU2002113750A/ru unknown
- 2000-10-25 AT AT00975917T patent/ATE339403T1/de not_active IP Right Cessation
- 2000-10-25 HK HK03101865.7A patent/HK1049831A1/zh unknown
- 2000-10-25 MX MXPA02004440A patent/MXPA02004440A/es unknown
- 2000-10-25 PL PL00355099A patent/PL355099A1/xx unknown
- 2000-10-25 SK SK595-2002A patent/SK5952002A3/sk unknown
- 2000-11-03 AR ARP000105800A patent/AR026351A1/es unknown
2002
- 2002-05-03 NO NO20022125A patent/NO20022125D0/no not_active Application Discontinuation
- 2002-06-03 ZA ZA200204433A patent/ZA200204433B/en unknown

Also Published As

Publication number	Publication date
BR0015334A (pt)	2002-07-09
ZA200204433B (en)	2003-09-03
MXPA02004440A (es)	2004-09-10
CZ20021440A3 (cs)	2002-07-17
EP1230215B1 (de)	2006-09-13
CN1382122A (zh)	2002-11-27
HUP0203288A3 (en)	2003-12-29
NO20022125L (no)	2002-05-03
ATE339403T1 (de)	2006-10-15
PL355099A1 (en)	2004-04-05
JP2003513070A (ja)	2003-04-08
CA2389709C (en)	2009-02-10
CA2389709A1 (en)	2001-05-10
HK1049831A1 (zh)	2003-05-30
HUP0203288A2 (hu)	2003-01-28
AU782477B2 (en)	2005-08-04
KR20020063173A (ko)	2002-08-01
SK5952002A3 (en)	2002-09-10
WO2001032618A1 (de)	2001-05-10
DE50013473D1 (de)	2006-10-26
AU1387301A (en)	2001-05-14
US6737436B1 (en)	2004-05-18
ES2272331T3 (es)	2007-05-01
AR026351A1 (es)	2003-02-05
DE19953025A1 (de)	2001-05-10
RU2002113750A (ru)	2004-01-10
EP1230215A1 (de)	2002-08-14

Publication	Publication Date	Title
NO20022125D0 (no)	2002-05-03	Pyrrolderivater som inhibitorer for fosfodiesterase VII
DK1289985T3 (da)	2004-04-05	Beta-carbolinderivater anvendelige som phosphodiesteraseinhibitorer
NO20023828L (no)	2002-09-30	Pyrimidin-4-on derivater som LDL-PLA2 inhibitorer
ATE278690T1 (de)	2004-10-15	Substituierte pyprolopyridinonderivate als phosphodiesterase-inhibitoren
DK1244647T3 (da)	2006-09-25	Quinzolinderivater som VIGF-inhibitorer
NO20015650D0 (no)	2001-11-20	Pyrrolotriazin-inhibitorer for kinaser
NO20021239L (no)	2002-03-13	Pteridinoner som kinase-inhibitorer
EE05430B1 (et)	2011-06-15	Imidasolo-5-l-2-anilino-primidiinid raku proliferatsiooni inhibitsiooni agensitena
DK1226143T3 (da)	2003-06-30	Imidazopyridinderivater som phosphodiesterase VII-inhibitorer
NO20022232D0 (no)	2002-05-10	Imidazolforbindelser for anvendelse som inhibitorer for fosfodiesterase VII
NO20016201D0 (no)	2001-12-18	Tienopyrimidiner som fosfodiesteraseinhibitorer
NO20021959D0 (no)	2002-04-25	Tetrahydrotiopyranftalazinon-derivater som PDE4-inhibitorer
NO20022123D0 (no)	2002-05-03	Osoksazolderivater for anvendelse som inhibitorer for fosfodiesterase VII
NO20016403L (no)	2002-03-01	Substituerte purinderivater som inhibitorer av celleadhesjon
DK1222193T3 (da)	2003-12-01	Imidazolderivater som phosphodiesterase VII-inhibitorer
PT1206462E (pt)	2003-10-31	Compostos heterociclicos para inibicao da angiogenese
ATE262517T1 (de)	2004-04-15	Thiopyranderivate as mmp-inhibitoren
AU3971700A (en)	2000-11-02	Cyclobutene-3,4-dione derivatives as inhibitors of phosphodiesterase
DK1296981T3 (da)	2005-07-25	Substituerede pyrrolopyridinonderivater som phosphodiesteraseinhibitorer
SI1289985T1 (en)	2004-04-30	Beta-carboline derivatives useful as inhibitors of phosphodiesterase
SI1226143T1 (en)	2003-10-31	Imidazopyridine derivatives used as phosphodiesterase vii inhibitors

Legal Events

Date	Code	Title	Description
2003-09-29	FC2A	Withdrawal, rejection or dismissal of laid open patent application