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NO20016403L - Substituerte purinderivater som inhibitorer av celleadhesjon - Google Patents

Substituerte purinderivater som inhibitorer av celleadhesjon

Info

Publication number
NO20016403L
NO20016403L NO20016403A NO20016403A NO20016403L NO 20016403 L NO20016403 L NO 20016403L NO 20016403 A NO20016403 A NO 20016403A NO 20016403 A NO20016403 A NO 20016403A NO 20016403 L NO20016403 L NO 20016403L
Authority
NO
Norway
Prior art keywords
inhibitors
cell adhesion
purine derivatives
substituted purine
substituted
Prior art date
Application number
NO20016403A
Other languages
English (en)
Other versions
NO20016403D0 (no
Inventor
Anuschirwan Peyman
Jochen Knolle
Thomas R Gadek
Jean-Francois Gourvest
Jean-Marie Ruxer
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of NO20016403D0 publication Critical patent/NO20016403D0/no
Publication of NO20016403L publication Critical patent/NO20016403L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20016403A 1999-07-02 2001-12-28 Substituerte purinderivater som inhibitorer av celleadhesjon NO20016403L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99112637A EP1065208A1 (en) 1999-07-02 1999-07-02 Substituted purine derivatives as inhibitors of cell adhesion
PCT/EP2000/005921 WO2001002399A1 (en) 1999-07-02 2000-06-26 Substituted purine derivatives as inhibitors of cell adhesion

Publications (2)

Publication Number Publication Date
NO20016403D0 NO20016403D0 (no) 2001-12-28
NO20016403L true NO20016403L (no) 2002-03-01

Family

ID=8238483

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20016403A NO20016403L (no) 1999-07-02 2001-12-28 Substituerte purinderivater som inhibitorer av celleadhesjon

Country Status (30)

Country Link
US (1) US6747016B1 (no)
EP (2) EP1065208A1 (no)
JP (1) JP2003503497A (no)
KR (1) KR20020015997A (no)
CN (1) CN1171888C (no)
AR (1) AR034242A1 (no)
AT (1) ATE262528T1 (no)
AU (1) AU774382B2 (no)
BG (1) BG106229A (no)
BR (1) BR0012050A (no)
CA (1) CA2376673A1 (no)
CZ (1) CZ20014553A3 (no)
DE (1) DE60009296T2 (no)
EA (1) EA005372B1 (no)
EE (1) EE200100713A (no)
ES (1) ES2219353T3 (no)
HU (1) HUP0300183A3 (no)
IL (1) IL147245A0 (no)
MX (1) MXPA01013241A (no)
MY (1) MY122631A (no)
NO (1) NO20016403L (no)
NZ (1) NZ516095A (no)
PL (1) PL352281A1 (no)
SK (1) SK18792001A3 (no)
TR (1) TR200103858T2 (no)
TW (1) TWI229080B (no)
UA (1) UA72923C2 (no)
WO (1) WO2001002399A1 (no)
YU (1) YU89701A (no)
ZA (1) ZA200200017B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10042655A1 (de) * 2000-08-31 2002-03-14 Aventis Pharma Gmbh Verfahren zur Herstellung von Inhibitoren der Zell-Adhäsion
FR2847254B1 (fr) * 2002-11-19 2005-01-28 Aventis Pharma Sa Nouveaux derives antagonistes du recepteur de la vitronectine, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les refermant
FR2870541B1 (fr) * 2004-05-18 2006-07-14 Proskelia Sas Derives de pyrimidines antigonistes du recepteur de la vitronectine
CN103265495B (zh) * 2005-12-29 2016-11-16 莱西肯医药有限公司 多环氨基酸衍生物及其使用方法
CL2007002994A1 (es) * 2006-10-19 2008-02-08 Wyeth Corp Compuestos derivados heterociclicos que contienen sulfamoilo, inhibidores de hsp90; composicion farmaceutica; y uso para el tratamiento del cancer, tal como cancer de mama, de colon y prostata, entre otros.
CN107450106A (zh) * 2017-09-28 2017-12-08 北京小米移动软件有限公司 饮水安全提示方法、装置及智能水杯
US12522583B2 (en) 2018-11-07 2026-01-13 Dana-Farber Cancer Institute, Inc. Benzimidazole derivatives and aza-benzimidazole derivatives as Janus kinase 2 inhibitors and uses thereof
WO2020097400A1 (en) 2018-11-07 2020-05-14 Dana-Farber Cancer Institute, Inc. Imidazopyridine derivatives and aza-imidazopyridine derivatives as janus kinase 2 inhibitors and uses thereof
US12415816B2 (en) 2018-11-07 2025-09-16 Dana-Farber Cancer Institute, Inc. Benzothiazole derivatives and 7-aza-benzothiazole derivatives as janus kinase 2 inhibitors and uses thereof
EP4146639A1 (en) 2020-05-06 2023-03-15 Ajax Therapeutics, Inc. 6-heteroaryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors
TW202241889A (zh) 2020-12-23 2022-11-01 美商雅捷可斯治療公司 作為ｊａｋ２抑制劑之６－雜芳基氧基苯并咪唑及氮雜苯并咪唑
TW202325289A (zh) 2021-11-09 2023-07-01 美商雅捷可斯治療公司 Ｊａｋ２抑制劑之形式及組合物
WO2023086319A1 (en) 2021-11-09 2023-05-19 Ajax Therapeutics, Inc. 6-he tero aryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2186720T3 (es) * 1994-05-27 2003-05-16 Merck & Co Inc Composiciones para inhibir la reabsorcion osea mediada por osteoclastos.
WO1998008840A1 (en) * 1996-08-29 1998-03-05 Merck & Co., Inc. Integrin antagonists
EP0946164A4 (en) * 1996-10-30 2000-08-23 Merck & Co Inc INTEGRIN ANTAGONISTS
DE19653646A1 (de) * 1996-12-20 1998-06-25 Hoechst Ag Substituierte Purinderivate, Verfahren zu deren Herstellung, sie enthaltende Mittel und deren Verwendung
JP2001509176A (ja) * 1997-01-17 2001-07-10 メルク エンド カンパニー インコーポレーテッド インテグリンアンタゴニスト
AU752882B2 (en) * 1998-01-23 2002-10-03 Aventis Pharma Deutschland Gmbh Novel sulfonamide derivatives as inhibitors of bone resorption and as inhibitors of cell adhesion
WO1999038621A1 (en) 1998-01-28 1999-08-05 Danmist Aps Method of piezoelectrically atomising and pumping fluids and piezoelectric fluid atomising and pumping device

Also Published As

Publication number Publication date
DE60009296D1 (de) 2004-04-29
ATE262528T1 (de) 2004-04-15
CA2376673A1 (en) 2001-01-11
PL352281A1 (en) 2003-08-11
JP2003503497A (ja) 2003-01-28
CZ20014553A3 (cs) 2002-06-12
EE200100713A (et) 2003-04-15
HUP0300183A3 (en) 2005-12-28
HUP0300183A2 (hu) 2003-06-28
NO20016403D0 (no) 2001-12-28
MXPA01013241A (es) 2002-06-21
TR200103858T2 (tr) 2002-06-21
WO2001002399A1 (en) 2001-01-11
KR20020015997A (ko) 2002-03-02
UA72923C2 (uk) 2005-05-16
CN1171888C (zh) 2004-10-20
EP1065208A1 (en) 2001-01-03
YU89701A (sh) 2004-09-03
AR034242A1 (es) 2004-02-18
BG106229A (bg) 2002-08-30
CN1371376A (zh) 2002-09-25
TWI229080B (en) 2005-03-11
EP1196416A1 (en) 2002-04-17
ES2219353T3 (es) 2004-12-01
AU774382B2 (en) 2004-06-24
US6747016B1 (en) 2004-06-08
ZA200200017B (en) 2003-01-02
SK18792001A3 (sk) 2002-07-02
EA005372B1 (ru) 2005-02-24
IL147245A0 (en) 2002-08-14
AU5534900A (en) 2001-01-22
EP1196416B1 (en) 2004-03-24
DE60009296T2 (de) 2005-05-25
NZ516095A (en) 2004-08-27
EA200200121A1 (ru) 2002-06-27
MY122631A (en) 2006-04-29
BR0012050A (pt) 2002-12-31

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application