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NO20020217D0 - Nitrogenholdige heterobicykler som faktor Xa-inhibitorer - Google Patents

Nitrogenholdige heterobicykler som faktor Xa-inhibitorer

Info

Publication number
NO20020217D0
NO20020217D0 NO20020217A NO20020217A NO20020217D0 NO 20020217 D0 NO20020217 D0 NO 20020217D0 NO 20020217 A NO20020217 A NO 20020217A NO 20020217 A NO20020217 A NO 20020217A NO 20020217 D0 NO20020217 D0 NO 20020217D0
Authority
NO
Norway
Prior art keywords
inhibitors
factor
nitrogen
heterobicycles
same
Prior art date
Application number
NO20020217A
Other languages
English (en)
Other versions
NO20020217L (no
Inventor
Irina Cipora Jacobson
Mimi Lifen Quan
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Publication of NO20020217D0 publication Critical patent/NO20020217D0/no
Publication of NO20020217L publication Critical patent/NO20020217L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20020217A 1999-07-16 2002-01-15 Nitrogenholdige heterobisykler som faktor Xa-inhibitorer NO20020217L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14434499P 1999-07-16 1999-07-16
PCT/US2000/018903 WO2001005784A1 (en) 1999-07-16 2000-07-12 NITROGEN CONTAINING HETEROBICYCLES AS FACTOR Xa INHIBITORS

Publications (2)

Publication Number Publication Date
NO20020217D0 true NO20020217D0 (no) 2002-01-15
NO20020217L NO20020217L (no) 2002-03-15

Family

ID=22508178

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20020217A NO20020217L (no) 1999-07-16 2002-01-15 Nitrogenholdige heterobisykler som faktor Xa-inhibitorer

Country Status (18)

Country Link
US (2) US6429205B1 (no)
EP (1) EP1196412B1 (no)
JP (1) JP2004507439A (no)
KR (1) KR20030011268A (no)
CN (1) CN1454211A (no)
AT (1) ATE268766T1 (no)
AU (1) AU2481501A (no)
BR (1) BR0013200A (no)
CA (1) CA2380727A1 (no)
DE (1) DE60011430T2 (no)
ES (1) ES2222257T3 (no)
HK (1) HK1045502B (no)
IL (1) IL147317A0 (no)
MX (1) MXPA02000537A (no)
NO (1) NO20020217L (no)
PL (1) PL357108A1 (no)
WO (1) WO2001005784A1 (no)
ZA (1) ZA200200094B (no)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6339099B1 (en) * 1997-06-20 2002-01-15 Dupont Pharmaceuticals Company Guanidine mimics as factor Xa inhibitors
AU5414000A (en) 1999-06-14 2001-01-02 Eli Lilly And Company Compounds
US20020013314A1 (en) * 2000-02-01 2002-01-31 Bing-Yan Zhu 3,4-dihydro-2H-benzo[1,4]oxazine inhibitors of factor Xa
AU2001234690A1 (en) 2000-02-01 2001-08-14 Cor Therapeutics, Inc. 2-(1h)-quinolone and 2-(1h)-quinoxalone inhibitors of factor xa
EP1283199A4 (en) * 2000-05-16 2003-12-17 Takeda Chemical Industries Ltd MELANINE CONCENTRATING HORMONE ANTAGONISTS
US6506771B2 (en) 2000-06-23 2003-01-14 Bristol-Myers Squibb Pharma Company Heteroaryl-phenyl heterobicyclic factor Xa inhibitors
WO2002000647A1 (en) 2000-06-23 2002-01-03 Bristol-Myers Squibb Pharma Company Heteroaryl-phenyl substituted factor xa inhibitors
TWI331526B (en) 2001-09-21 2010-10-11 Bristol Myers Squibb Pharma Co Lactam-containing compounds and derivatives thereof as factor xa inhibitors
CN101357914A (zh) 2001-09-21 2009-02-04 百时美施贵宝公司 含有内酰胺的化合物及其衍生物作为Xa因子的抑制剂
TW200302225A (en) 2001-12-04 2003-08-01 Bristol Myers Squibb Co Substituted amino methyl factor Xa inhibitors
AU2002350217A1 (en) 2001-12-04 2003-06-17 Bristol-Myers Squibb Company Glycinamides as factor xa inhibitors
CN100349890C (zh) * 2002-01-22 2007-11-21 纳幕尔杜邦公司 用于防治无脊椎害虫的喹唑啉(二)酮
KR101022977B1 (ko) 2002-03-26 2011-03-18 베링거 인겔하임 파마슈티칼즈, 인코포레이티드 글루코코르티코이드 모사체, 이의 제조방법, 약제학적조성물 및 이의 용도
US7312214B2 (en) 2002-05-10 2007-12-25 Bristol-Myers Squibb Company 1, 1-disubstituted cycloalkyl derivatives as factor Xa inhibitors
AU2003259747A1 (en) 2002-08-21 2004-03-11 Boehringer Ingelheim Pharmaceuticals, Inc. Substituted hihydroquinolines as glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
HUE025683T2 (hu) 2002-12-03 2016-04-28 Pharmacyclics Llc VIIA faktor inhibitor 2-(2-hidroxi-bifenil-3-il)-1H-benzoimidazol-5-karboxamidin-származékok
ATE444292T1 (de) * 2002-12-23 2009-10-15 Sanofi Aventis Deutschland Pyrazolderivate als faktor-xa-inhibitoren
US7429581B2 (en) 2002-12-23 2008-09-30 Sanofi-Aventis Deutschland Gmbh Pyrazole-derivatives as factor Xa inhibitors
EP1479678A1 (en) * 2003-05-19 2004-11-24 Aventis Pharma Deutschland GmbH Pyrazole-derivatives as factor xa inhibitors
US7122557B2 (en) 2003-03-18 2006-10-17 Bristol-Myers Squibb Company Sulfonyl-amidino-containing and tetrahydropyrimidino-containing compounds as factor Xa inhibitors
US7129264B2 (en) * 2003-04-16 2006-10-31 Bristol-Myers Squibb Company Biarylmethyl indolines and indoles as antithromboembolic agents
UY28526A1 (es) 2003-09-24 2005-04-29 Boehringer Ingelheim Pharma Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos
US20050124664A1 (en) * 2003-10-30 2005-06-09 Eric Sartori Urea thiadiazole inhibitors of plasminogen activator inhibior-1
US7795272B2 (en) 2004-03-13 2010-09-14 Boehringer Ingelheim Pharmaceutical, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
AU2005299693B2 (en) * 2004-10-26 2012-07-05 Janssen Pharmaceutica, N.V. Factor Xa compounds
ES2326907T3 (es) 2004-12-27 2009-10-21 Boehringer Ingelheim Pharmaceuticals Inc. Mimeticos de glucocorticoides, metodos para su preparacion, composiciones farmaceuticas y su uso.
GT200600042A (es) * 2005-02-10 2006-09-27 Aventis Pharma Inc Compuestos de bis arilo y heteroarilo sustituido como antagonistas selectivos de 5ht2a
DE102005038947A1 (de) 2005-05-18 2006-11-30 Grünenthal GmbH Substituierte Benzo[d]isoxazol-3-yl-amin-Verbindungen und deren Verwendung in Arzneimitteln
RU2009125614A (ru) 2006-12-06 2011-01-20 Бёрингер Ингельхайм Интернациональ Гмбх (De) Глюкокортикоидные миметики, способы их получения, фармацевтические композиции и их применения
NZ580801A (en) * 2007-05-10 2012-09-28 Bristol Myers Squibb Co Aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
BRPI0915680A2 (pt) 2008-06-06 2019-09-24 Boehringer Ingelheim Int miméticos de glicocorticoide, métodos de prepará-los, composições farmacêuticas, e usos dos mesmos
EP2865671B1 (en) * 2012-06-22 2017-11-01 Sumitomo Chemical Company, Ltd Fused heterocyclic compound
JP7017524B2 (ja) * 2016-05-23 2022-02-15 ザ ロックフェラー ユニバーシティー 自己免疫疾患を治療するためのアミノアシルインダゾール免疫調節薬

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2240946C (en) 1995-12-21 2002-09-10 The Dupont Merck Pharmaceutical Company Isoxazoline, isothiazoline and pyrazoline factor xa inhibitors
WO1998028282A2 (en) 1996-12-23 1998-07-02 Du Pont Pharmaceuticals Company OXYGEN OR SULFUR CONTAINING 5-MEMBERED HETEROAROMATICS AS FACTOR Xa INHIBITORS
HUP0000735A3 (en) * 1996-12-23 2002-03-28 Bristol Myers Squibb Pharma Co Nitrogen containing heteroaromatics as factor xa inhibitors
ZA985247B (en) * 1997-06-19 1999-12-17 Du Pont Merck Pharma Guanidine mimics as factor Xa inhibitors.
EE9900584A (et) 1997-06-19 2000-08-15 Dupont Pharmaceuticals Company Neutraalse P1 spetsiifilisusrühmaga faktori Xa inhibiitorid
JP2001526268A (ja) 1997-12-22 2001-12-18 デュポン ファーマシューティカルズ カンパニー Ｘａ因子阻害剤としての、オルト−置換Ｐ１を有する、窒素含有複素環式芳香族化合物

Also Published As

Publication number Publication date
DE60011430T2 (de) 2005-07-07
NO20020217L (no) 2002-03-15
WO2001005784A1 (en) 2001-01-25
ATE268766T1 (de) 2004-06-15
BR0013200A (pt) 2002-05-07
MXPA02000537A (es) 2004-09-10
EP1196412A1 (en) 2002-04-17
US6429205B1 (en) 2002-08-06
JP2004507439A (ja) 2004-03-11
HK1045502A1 (en) 2002-11-29
CA2380727A1 (en) 2001-01-25
KR20030011268A (ko) 2003-02-07
PL357108A1 (en) 2004-07-12
DE60011430D1 (de) 2004-07-15
IL147317A0 (en) 2002-08-14
ES2222257T3 (es) 2005-02-01
HK1045502B (en) 2004-12-10
US20030096820A1 (en) 2003-05-22
AU2481501A (en) 2001-02-05
ZA200200094B (en) 2003-04-30
US6716841B2 (en) 2004-04-06
CN1454211A (zh) 2003-11-05
EP1196412B1 (en) 2004-06-09

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