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NO20013384L - Imidazo[4,5-c]pyridin-4-on-derivater - Google Patents

Imidazo[4,5-c]pyridin-4-on-derivater

Info

Publication number
NO20013384L
NO20013384L NO20013384A NO20013384A NO20013384L NO 20013384 L NO20013384 L NO 20013384L NO 20013384 A NO20013384 A NO 20013384A NO 20013384 A NO20013384 A NO 20013384A NO 20013384 L NO20013384 L NO 20013384L
Authority
NO
Norway
Prior art keywords
imidazo
pyridine
derivatives
prophylaxis
inhibitors
Prior art date
Application number
NO20013384A
Other languages
English (en)
Other versions
NO20013384D0 (no
Inventor
Werner Mederski
Horst Juraszyk
Hanns Wurziger
Christos Tsaklakidis
Dieter Dorsch
Sabine Bernotat-Danielowski
Guido Melzer
Soheila Anzali
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO20013384L publication Critical patent/NO20013384L/no
Publication of NO20013384D0 publication Critical patent/NO20013384D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Nye forbindelser med formel (I) hvor R, R1, R2, RJ og n har de i krav l angitte betydninger, er inhibitorer for koagulasjonsfaktor Xa og kan anven- des til profylakse og/eller behandling av tromboemboliske sykdommer.
NO20013384A 1999-01-08 2001-07-06 Imidazo[4,5-c]pyridin-4-on-derivater NO20013384D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19900471A DE19900471A1 (de) 1999-01-08 1999-01-08 Imidazo[4,5c]-pyridin-4-on-derivate
PCT/EP1999/010236 WO2000040583A2 (de) 1999-01-08 1999-12-21 Imidazo[4,5-c]-pyridin-4-on-derivate

Publications (2)

Publication Number Publication Date
NO20013384L true NO20013384L (no) 2001-07-06
NO20013384D0 NO20013384D0 (no) 2001-07-06

Family

ID=7893790

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013384A NO20013384D0 (no) 1999-01-08 2001-07-06 Imidazo[4,5-c]pyridin-4-on-derivater

Country Status (16)

Country Link
EP (1) EP1149099A2 (no)
JP (1) JP2002534429A (no)
KR (1) KR20010086085A (no)
CN (1) CN1333772A (no)
AR (1) AR022220A1 (no)
AU (1) AU3041700A (no)
BR (1) BR9916774A (no)
CA (1) CA2357771A1 (no)
CZ (1) CZ20012407A3 (no)
DE (1) DE19900471A1 (no)
HU (1) HUP0105054A3 (no)
NO (1) NO20013384D0 (no)
PL (1) PL349341A1 (no)
SK (1) SK9442001A3 (no)
WO (1) WO2000040583A2 (no)
ZA (1) ZA200106454B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL142959A0 (en) 1998-12-23 2002-04-21 Du Pont Pharm Co Nitrogen containing heterobicycles as factor xa inhibitors
US6506771B2 (en) 2000-06-23 2003-01-14 Bristol-Myers Squibb Pharma Company Heteroaryl-phenyl heterobicyclic factor Xa inhibitors
WO2002094197A2 (en) 2001-05-22 2002-11-28 Bristol-Myers Squibb Company Bicyclic inhibitors of factor xa
GB0215293D0 (en) 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
GB0225399D0 (en) * 2002-10-31 2002-12-11 Merck Sharp & Dohme Therapeutic agents
AU2003302238A1 (en) 2002-12-03 2004-06-23 Axys Pharmaceuticals, Inc. 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors
US7550590B2 (en) 2003-03-25 2009-06-23 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
EP1625122A1 (en) 2003-05-14 2006-02-15 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
US20050070531A1 (en) 2003-08-13 2005-03-31 Syrrx, Inc. Dipeptidyl peptidase inhibitors
EP1706403B9 (en) 2003-12-22 2012-07-25 K.U.Leuven Research & Development Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment
ATE426601T1 (de) 2004-12-21 2009-04-15 Gilead Sciences Inc Imidazoa4,5-cupyridinverbindung und verfahren zur antiviralen behandlung
KR101083506B1 (ko) 2005-07-15 2011-11-16 에프. 호프만-라 로슈 아게 신규한 헤테로아릴 융합된 환형 아민
US20070060530A1 (en) 2005-09-14 2007-03-15 Christopher Ronald J Administration of dipeptidyl peptidase inhibitors
EP1924567B1 (en) 2005-09-16 2012-08-22 Takeda Pharmaceutical Company Limited Process for the preparation of pyrimidinedione derivatives
WO2007112347A1 (en) 2006-03-28 2007-10-04 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
ATE454384T1 (de) 2006-07-07 2010-01-15 Gilead Sciences Inc Neue pyridazinverbindung und ihre verwendung
TW200838536A (en) 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound
CN107074846B (zh) * 2014-08-12 2020-05-19 先正达参股股份有限公司 具有含硫取代基的杀有害生物活性杂环衍生物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW219935B (no) * 1991-12-25 1994-02-01 Mitsubishi Chemicals Co Ltd
CA2309347A1 (en) * 1997-12-01 1999-06-10 Merck & Co., Inc. Thrombin inhibitors

Also Published As

Publication number Publication date
WO2000040583A3 (de) 2000-09-21
ZA200106454B (en) 2002-11-06
CA2357771A1 (en) 2000-07-13
PL349341A1 (en) 2002-07-15
AR022220A1 (es) 2002-09-04
DE19900471A1 (de) 2000-07-13
CZ20012407A3 (cs) 2001-12-12
JP2002534429A (ja) 2002-10-15
SK9442001A3 (en) 2002-05-09
BR9916774A (pt) 2001-10-30
HUP0105054A2 (hu) 2002-05-29
EP1149099A2 (de) 2001-10-31
HUP0105054A3 (en) 2002-12-28
AU3041700A (en) 2000-07-24
KR20010086085A (ko) 2001-09-07
WO2000040583A2 (de) 2000-07-13
NO20013384D0 (no) 2001-07-06
CN1333772A (zh) 2002-01-30

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