NO20011293L - Faktor VIIa-inhibitorer - Google Patents

Faktor VIIa-inhibitorer

Info

Publication number: NO20011293L
Authority: NO; Norway
Prior art keywords: factor viia; viia inhibitors; inhibitors; factor; viia
Prior art date: 1998-09-15

Application number

NO20011293A

Other languages

English (en)

Other versions

NO328523B1 (no

NO20011293D0 (no

Inventor

Pavel Safar

Alena Safarova

Peter Wildgoose

Original Assignee

Aventis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-09-15

Filing date

2001-03-14

Publication date

2001-05-04

2001-03-14 Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh

2001-03-14 Publication of NO20011293D0 publication Critical patent/NO20011293D0/no

2001-05-04 Publication of NO20011293L publication Critical patent/NO20011293L/no

2010-03-08 Publication of NO328523B1 publication Critical patent/NO328523B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/105831—Protein or peptide standard or control [e.g., hemoglobin, etc.]

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO20011293A 1998-09-15 2001-03-14 Faktor VIIa-inhibitorer, fremgangsmate for fremstilling av slike og farmasoytisk preparat omfattende slike, samt anvendelse av inhibitorene for fremstilling av farmasoytisk preparat. NO328523B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP98117506A EP0987274A1 (en)	1998-09-15	1998-09-15	Factor VIIa Inhibitors
PCT/EP1999/006449 WO2000015658A1 (en)	1998-09-15	1999-09-02	FACTOR VIIa INHIBITORS

Publications (3)

Publication Number	Publication Date
NO20011293D0 NO20011293D0 (no)	2001-03-14
NO20011293L true NO20011293L (no)	2001-05-04
NO328523B1 NO328523B1 (no)	2010-03-08

Family

ID=8232644

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20011293A NO328523B1 (no)	1998-09-15	2001-03-14	Faktor VIIa-inhibitorer, fremgangsmate for fremstilling av slike og farmasoytisk preparat omfattende slike, samt anvendelse av inhibitorene for fremstilling av farmasoytisk preparat.

Country Status (25)

Country	Link
US (1)	US6287794B1 (no)
EP (2)	EP0987274A1 (no)
JP (1)	JP4537581B2 (no)
KR (1)	KR100665490B1 (no)
CN (1)	CN1203087C (no)
AR (1)	AR027814A1 (no)
AT (1)	ATE460424T1 (no)
AU (1)	AU760580B2 (no)
BR (1)	BR9913742A (no)
CA (1)	CA2344048A1 (no)
CZ (1)	CZ300249B6 (no)
DE (1)	DE69942123D1 (no)
HK (1)	HK1040253B (no)
HU (1)	HUP0103851A3 (no)
ID (1)	ID28494A (no)
IL (2)	IL141415A0 (no)
MY (1)	MY125150A (no)
NO (1)	NO328523B1 (no)
NZ (1)	NZ510509A (no)
PL (1)	PL203227B1 (no)
RU (1)	RU2223967C2 (no)
TR (1)	TR200100766T2 (no)
TW (1)	TW576839B (no)
WO (1)	WO2000015658A1 (no)
ZA (1)	ZA200101861B (no)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0987274A1 (en) *	1998-09-15	2000-03-22	Hoechst Marion Roussel Deutschland GmbH	Factor VIIa Inhibitors
US6472393B1 (en)	1999-01-13	2002-10-29	Genentech, Inc.	Serine protease inhibitors
EP1059302A1 (en) *	1999-06-08	2000-12-13	Aventis Pharma Deutschland GmbH	Factor VIIa inhibitors
BR0014667A (pt) *	1999-10-01	2002-07-02	Chugai Pharmaceutical Co Ltd	Prevenção e tratamento de doenças relacionadas à coagulação sanguìnea
EP1095933A1 (en)	1999-10-30	2001-05-02	Aventis Pharma Deutschland GmbH	Novel N-guanidinoalkylamides, their preparation, their use, and pharmaceutical preparations comprising them
EP1162194A1 (en) *	2000-06-06	2001-12-12	Aventis Pharma Deutschland GmbH	Factor VIIa inhibitory (thio)urea derivatives, their preparation and their use
GB0014134D0 (en) *	2000-06-10	2000-08-02	Astrazeneca Ab	Combination therapy
WO2002034711A1 (en)	2000-10-20	2002-05-02	Biocryst Pharmaceuticals, Inc.	Biaryl compounds as serine protease inhibitors
BR0115938A (pt)	2000-12-06	2003-12-23	Aventis Pharma Deustschland Gm	Derivados de guanidina e amidina com inibidores do fator xa
EP1364960A4 (en)	2001-02-02	2005-05-18	Chugai Pharmaceutical Co Ltd	PEPTIDE DERIVATIVES
EP1270551A1 (en) *	2001-06-26	2003-01-02	Aventis Pharma Deutschland GmbH	Urea derivatives with antiproteolytic activity
EP1314733A1 (en)	2001-11-22	2003-05-28	Aventis Pharma Deutschland GmbH	Indole-2-carboxamides as factor Xa inhibitors
AU2003290663A1 (en) *	2002-11-13	2004-06-03	Haematologic Technologies, Inc.	Assay for tissue factor and factor viia
US7358268B2 (en)	2002-12-04	2008-04-15	Sanofi-Aventis Deutschland Gmbh	Imidazole derivatives as factor Xa inhibitors
US7429581B2 (en)	2002-12-23	2008-09-30	Sanofi-Aventis Deutschland Gmbh	Pyrazole-derivatives as factor Xa inhibitors
US7223780B2 (en)	2003-05-19	2007-05-29	Sanofi-Aventis Deutschland Gmbh	Triazole-derivatives as blood clotting enzyme factor Xa inhibitors
US7741341B2 (en)	2003-05-19	2010-06-22	Sanofi-Aventis Deutschland Gmbh	Benzimidazole-derivatives as factor Xa inhibitors
EP1479677A1 (en) *	2003-05-19	2004-11-24	Aventis Pharma Deutschland GmbH	New indole derivatives as factor xa inhibitors
US7317027B2 (en)	2003-05-19	2008-01-08	Sanofi-Aventis Deutschland Gmbh	Azaindole-derivatives as factor Xa inhibitors
EP1479680A1 (en)	2003-05-19	2004-11-24	Aventis Pharma Deutschland GmbH	Azaindole derivatives as Factor Xa inhibitors
EP1479675A1 (en)	2003-05-19	2004-11-24	Aventis Pharma Deutschland GmbH	Indazole-derivatives as factor Xa inhibitors
WO2004113316A1 (en)	2003-05-20	2004-12-29	Genentech, Inc.	Benzofuran inhibitors of factor viia
JP2007505160A (ja)	2003-05-20	2007-03-08	ジェネンテック・インコーポレーテッド	第ＶＩＩａ因子のアシルスルファミド阻害剤
EP1568698A1 (en)	2004-02-27	2005-08-31	Aventis Pharma Deutschland GmbH	Pyrrole-derivatives as factor Xa inhibitors
CN103251647A (zh) *	2004-05-27	2013-08-21	巴克斯特国际公司	应用硫酸多糖治疗出血障碍的方法
WO2008107362A2 (en) *	2007-03-07	2008-09-12	Novo Nordisk Health Care Ag	Stabiliser and inhibitors of factor vii
EP2176223B1 (en)	2007-07-10	2013-01-23	Sanofi	Malonamide derivatives with antithrombotic activity
JP2011510043A (ja) *	2008-01-23	2011-03-31	ノボノルディスクヘルスケアアーゲー	新規血液凝固因子インヒビター
TR201807926T4 (tr)	2011-02-04	2018-06-21	Octapharma Ag	Koagülasyon faktörlerinin çökeltme yoluyla etkisizleştirilmesine/çıkarılmasına yönelik usul.
CA3112175A1 (en) *	2018-09-11	2020-03-19	Anbition S.R.L.	Peptides and medical uses thereof
KR20210062649A (ko) *	2018-09-11	2021-05-31	앤비션 에스.알.엘.	펩티드 및 이의 의학적 용도
JP7775080B2 (ja)	2019-07-01	2025-11-25	トニックスファーマリミテッド	抗ｃｄ１５４抗体およびその使用
MX2023008055A (es)	2021-01-06	2023-08-22	Tonix Pharma Ltd	Métodos para inducir tolerancia inmune con anticuerpos anti-cd154 modificados.
GB202209228D0 (en) *	2022-06-23	2022-08-10	Univ Strathclyde	Modified amino acids and uses thereof
WO2025248134A1 (en)	2024-05-31	2025-12-04	Tonix Pharma Limited	Treatment methods comprising administration of modified cd154 antibodies

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5023236A (en) *	1988-04-07	1991-06-11	Corvas, Inc.	Factor VII/VIIA active site inhibitors
WO1990003390A1 (en) *	1988-09-23	1990-04-05	Corvas, Inc.	Peptidyl inhibitors of the initiation of coagulation
CA2008116C (en) *	1989-02-23	2001-11-20	Thomas Weller	Glycine derivatives
US5190919A (en) *	1989-11-13	1993-03-02	Board Of Regents, The University Of Texas System	Antihemostatic factor vii peptides
HU206372B (en) *	1990-09-03	1992-10-28	Richter Gedeon Vegyeszet	Process for producing new oligopeptides which selectively inhibit proliferation of haemopoietic cells and pharmaceutical compositions comprising same
US5506134A (en)	1990-10-22	1996-04-09	Corvas International, Inc.	Hypridoma and monoclonal antibody which inhibits blood coagulation tissue factor/factor VIIa complex
US5833982A (en)	1991-02-28	1998-11-10	Zymogenetics, Inc.	Modified factor VII
US5788965A (en)	1991-02-28	1998-08-04	Novo Nordisk A/S	Modified factor VII
SE9301916D0 (sv) *	1993-06-03	1993-06-03	Ab Astra	New peptides derivatives
ATE171950T1 (de) *	1993-06-18	1998-10-15	Nycomed Imaging As	Faktor vii-peptide
US5849510A (en) *	1994-04-26	1998-12-15	Selectide Corporation	Factor Xa inhibitors
DE69532754T2 (de) *	1994-04-26	2005-03-10	Aventis Pharmaceuticals, Inc.	Faktor xa inhibitoren
RU2097033C1 (ru) *	1994-09-30	1997-11-27	Московская государственная академия тонкой химической технологии им.М.В.Ломоносова	Имидазолсодержащие ингибиторы катепсин g-индуцированной агрегации тромбоцитов
US5837684A (en) *	1995-06-07	1998-11-17	Nycomed Imaging As	Peptides
AU2056197A (en) *	1996-02-22	1997-09-10	Du Pont Merck Pharmaceutical Company, The	M-amidino phenyl analogs as factor xa inhibitors
EP0987274A1 (en) *	1998-09-15	2000-03-22	Hoechst Marion Roussel Deutschland GmbH	Factor VIIa Inhibitors

1998
- 1998-09-15 EP EP98117506A patent/EP0987274A1/en not_active Withdrawn
1999
- 1999-09-02 WO PCT/EP1999/006449 patent/WO2000015658A1/en not_active Ceased
- 1999-09-02 CN CNB998109169A patent/CN1203087C/zh not_active Expired - Fee Related
- 1999-09-02 HK HK02101586.6A patent/HK1040253B/zh not_active IP Right Cessation
- 1999-09-02 TR TR2001/00766T patent/TR200100766T2/xx unknown
- 1999-09-02 AT AT99969095T patent/ATE460424T1/de not_active IP Right Cessation
- 1999-09-02 EP EP99969095A patent/EP1114061B1/en not_active Expired - Lifetime
- 1999-09-02 HU HU0103851A patent/HUP0103851A3/hu unknown
- 1999-09-02 CZ CZ20010914A patent/CZ300249B6/cs not_active IP Right Cessation
- 1999-09-02 DE DE69942123T patent/DE69942123D1/de not_active Expired - Lifetime
- 1999-09-02 RU RU2001110086/04A patent/RU2223967C2/ru not_active IP Right Cessation
- 1999-09-02 ID IDW20010598A patent/ID28494A/id unknown
- 1999-09-02 PL PL346781A patent/PL203227B1/pl not_active IP Right Cessation
- 1999-09-02 CA CA002344048A patent/CA2344048A1/en not_active Abandoned
- 1999-09-02 JP JP2000570196A patent/JP4537581B2/ja not_active Expired - Fee Related
- 1999-09-02 AU AU59723/99A patent/AU760580B2/en not_active Ceased
- 1999-09-02 KR KR1020017003350A patent/KR100665490B1/ko not_active Expired - Fee Related
- 1999-09-02 IL IL14141599A patent/IL141415A0/xx active IP Right Grant
- 1999-09-02 NZ NZ510509A patent/NZ510509A/xx not_active IP Right Cessation
- 1999-09-02 BR BR9913742-9A patent/BR9913742A/pt not_active Application Discontinuation
- 1999-09-13 AR ARP990104586A patent/AR027814A1/es active IP Right Grant
- 1999-09-14 MY MYPI99003984A patent/MY125150A/en unknown
- 1999-09-14 US US09/395,572 patent/US6287794B1/en not_active Expired - Lifetime
- 1999-09-20 TW TW088115707A patent/TW576839B/zh active
2001
- 2001-02-13 IL IL141415A patent/IL141415A/en not_active IP Right Cessation
- 2001-03-06 ZA ZA200101861A patent/ZA200101861B/en unknown
- 2001-03-14 NO NO20011293A patent/NO328523B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
MY125150A (en)	2006-07-31
HUP0103851A2 (hu)	2002-04-29
EP1114061A1 (en)	2001-07-11
JP4537581B2 (ja)	2010-09-01
ID28494A (id)	2001-05-31
KR100665490B1 (ko)	2007-01-10
RU2223967C2 (ru)	2004-02-20
PL203227B1 (pl)	2009-09-30
CN1203087C (zh)	2005-05-25
CZ300249B6 (cs)	2009-04-01
CA2344048A1 (en)	2000-03-23
US6287794B1 (en)	2001-09-11
CZ2001914A3 (en)	2001-06-13
KR20010075130A (ko)	2001-08-09
IL141415A (en)	2006-09-05
CN1318069A (zh)	2001-10-17
AU760580B2 (en)	2003-05-15
DE69942123D1 (de)	2010-04-22
NO328523B1 (no)	2010-03-08
EP0987274A1 (en)	2000-03-22
WO2000015658A1 (en)	2000-03-23
PL346781A1 (en)	2002-02-25
BR9913742A (pt)	2001-06-05
AR027814A1 (es)	2003-04-16
NO20011293D0 (no)	2001-03-14
TR200100766T2 (tr)	2001-10-22
NZ510509A (en)	2002-09-27
IL141415A0 (en)	2002-03-10
HK1040253A1 (en)	2002-05-31
JP2002524571A (ja)	2002-08-06
HUP0103851A3 (en)	2002-05-28
TW576839B (en)	2004-02-21
EP1114061B1 (en)	2010-03-10
ZA200101861B (en)	2001-10-22
AU5972399A (en)	2000-04-03
ATE460424T1 (de)	2010-03-15
HK1040253B (zh)	2005-09-02

Publication	Publication Date	Title
NO20011293L (no)	2001-05-04	Faktor VIIa-inhibitorer
NO20003808D0 (no)	2000-07-25	Substituerte oksoazaheterosyklylfaktor Xa inhibitorer
NO20021230L (no)	2002-05-21	Faktor Xa inhibitorer
ATE245142T1 (de)	2003-08-15	No-synthase inhibitoren
FI964317A7 (fi)	1996-10-25	Tekijän-Xa-inhibiittoreita
NO20013072L (no)	2001-06-20	Nitrogenholdige heterocykler som faktor Xa-inhibitorer
DK1027332T3 (da)	2004-10-04	Hidtil ukendte lactametalloproteaseinhibitorer
DK0958287T3 (da)	2003-01-20	Sulfamidmetalloprotease-inhibitorer
NO20004497L (no)	2000-11-07	Modifisert faktor VIII
EP1055911A4 (en)	2003-04-23	NAVIGATOR
ATE246707T1 (de)	2003-08-15	Faktor viia inhibitore
ATE252547T1 (de)	2003-11-15	Matrixmetalloproteinaseinhibitoren
ID27766A (id)	2001-04-26	Garam-garam paroksetin
DE69903507D1 (de)	2002-11-21	Beizvorrichtung
FR2782671B3 (fr)	2000-07-21	Livre
DE69901764D1 (de)	2002-07-18	Beizvorrichtung
DE59901997D1 (de)	2002-08-14	Thermochrome beschichtung
ATA67498A (de)	1999-12-15	Breitschlitzdüse
DE69932221D1 (de)	2006-08-17	Selbserhöhte Wortleitung
DE19980061D2 (de)	2000-01-27	Breitschlitzdüse
IT245169Y1 (it)	2002-03-19	I moduli
FI3785U1 (fi)	1999-02-18	Puupaneeli
SE9801103D0 (sv)	1998-03-30	Gradning
FI3562U1 (fi)	1998-08-31	Päällyste
FI3536U1 (fi)	1998-08-17	Päällystin

Legal Events

Date	Code	Title	Description
2011-05-09	MM1K	Lapsed by not paying the annual fees