[go: up one dir, main page]

NO20006576L - Et substituert triazol-pyridazinderivat og farmasöytiske preparater fremstilt av dette - Google Patents

Et substituert triazol-pyridazinderivat og farmasöytiske preparater fremstilt av dette

Info

Publication number
NO20006576L
NO20006576L NO20006576A NO20006576A NO20006576L NO 20006576 L NO20006576 L NO 20006576L NO 20006576 A NO20006576 A NO 20006576A NO 20006576 A NO20006576 A NO 20006576A NO 20006576 L NO20006576 L NO 20006576L
Authority
NO
Norway
Prior art keywords
pharmaceutical preparations
substituted triazole
pyridazine derivative
pyridazine
derivative
Prior art date
Application number
NO20006576A
Other languages
English (en)
Other versions
NO20006576D0 (no
NO317992B1 (no
Inventor
William Robert Carling
Jose Luis Castro Pineiro
Cameron John Cowden
Anthony John Davies
Andrew Madin
James Francis Mccabe
Gareth Edward Stephen Pearce
Leslie Joseph Street
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of NO20006576D0 publication Critical patent/NO20006576D0/no
Publication of NO20006576L publication Critical patent/NO20006576L/no
Publication of NO317992B1 publication Critical patent/NO317992B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20006576A 1998-06-24 2000-12-21 7-(1,1-dimetyletyl)-6-(2-etyl-2H-1.2.4-triazol-3-ylmetoksy)-3-(2-fluorfenyl)-1-2-4-triazol[4,3,-6]pyridazin, vannfri polymorf som omfatter denne, farmasoytisk preparat som omfatter denne, anvendelse av denne for fremstilling av et medikament og fremgangsmate for fremstilling av denne forbindelsen NO317992B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9813576.7A GB9813576D0 (en) 1998-06-24 1998-06-24 Therapeutic agents
PCT/GB1999/001897 WO1999067245A1 (en) 1998-06-24 1999-06-15 A substituted triazolo-pyridazine derivative, pharmaceutical compositions made therefrom

Publications (3)

Publication Number Publication Date
NO20006576D0 NO20006576D0 (no) 2000-12-21
NO20006576L true NO20006576L (no) 2001-02-14
NO317992B1 NO317992B1 (no) 2005-01-17

Family

ID=10834265

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20006576A NO317992B1 (no) 1998-06-24 2000-12-21 7-(1,1-dimetyletyl)-6-(2-etyl-2H-1.2.4-triazol-3-ylmetoksy)-3-(2-fluorfenyl)-1-2-4-triazol[4,3,-6]pyridazin, vannfri polymorf som omfatter denne, farmasoytisk preparat som omfatter denne, anvendelse av denne for fremstilling av et medikament og fremgangsmate for fremstilling av denne forbindelsen

Country Status (35)

Country Link
US (1) US6630471B1 (no)
EP (1) EP1090004B1 (no)
JP (1) JP4749545B2 (no)
KR (1) KR100604108B1 (no)
CN (1) CN1138779C (no)
AR (1) AR018925A1 (no)
AT (1) ATE239730T1 (no)
AU (1) AU757315B2 (no)
BG (1) BG64989B1 (no)
BR (1) BR9911563A (no)
CA (1) CA2335328C (no)
CO (1) CO5031239A1 (no)
CZ (1) CZ291409B6 (no)
DE (1) DE69907675T2 (no)
EA (1) EA003332B1 (no)
EE (1) EE200000767A (no)
ES (1) ES2196824T3 (no)
GB (1) GB9813576D0 (no)
GE (1) GEP20033143B (no)
HR (1) HRP20000879A2 (no)
HU (1) HUP0102894A3 (no)
ID (1) ID27771A (no)
IL (2) IL139775A0 (no)
IS (1) IS2258B (no)
MY (1) MY124341A (no)
NO (1) NO317992B1 (no)
NZ (1) NZ508290A (no)
PE (1) PE20000710A1 (no)
PL (1) PL204650B1 (no)
RS (1) RS49746B (no)
SK (1) SK285307B6 (no)
TR (1) TR200003789T2 (no)
TW (1) TWI222449B (no)
WO (1) WO1999067245A1 (no)
ZA (1) ZA200007485B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2345443A (en) * 1999-01-08 2000-07-12 Merck Sharp & Dohme Use of triazolo-pyridazines for treating premenstrual syndrome
US20050042194A1 (en) 2000-05-11 2005-02-24 A.P. Pharma, Inc. Semi-solid delivery vehicle and pharmaceutical compositions
GB0111191D0 (en) * 2001-05-08 2001-06-27 Merck Sharp & Dohme Therapeutic agents
RU2005122484A (ru) * 2002-12-18 2006-01-20 Вертекс Фармасьютикалз Инкорпорейтед (Us) Композиции, используемые в качестве ингибиторов протеинкиназ
WO2006061428A2 (en) * 2004-12-10 2006-06-15 Universität Zürich Gaba-a alpha 2 and alpha 3 receptor agonists for treating neuropathic, inflammatory and migraine associated pain
JP2012531419A (ja) * 2009-06-23 2012-12-10 コンサート ファーマシューティカルズ インコーポレイテッド Ｇａｂａ−ａ受容体修飾物質としての重水素修飾されたトリアゾロピリダジン誘導体
US20110082147A1 (en) * 2009-07-24 2011-04-07 Concert Pharmaceuticals, Inc. Substituted imidazotriazines
WO2011047315A1 (en) 2009-10-15 2011-04-21 Concert Pharmaceuticals, Inc. Subsitituted benzimidazoles
PH12012501361A1 (en) 2009-12-31 2012-10-22 Centro Nac De Investigaciones Oncologicas Cnio Tricyclic compounds for use as kinase inhibitors
WO2012098387A1 (en) * 2011-01-18 2012-07-26 Centro Nacional De Investigaciones Oncológicas (Cnio) 6, 7-ring-fused triazolo [4, 3 - b] pyridazine derivatives as pim inhibitors
MX356683B (es) 2011-09-27 2018-06-08 Genfit Derivados de triazolpiridazinas 6-sustituidas como agonistas rev-erb.
EP3407886A1 (en) 2016-01-27 2018-12-05 Universität Zürich Use of gabaa receptor modulators for treatment of itch
KR20250057112A (ko) * 2018-04-18 2025-04-28 뉴로사이클 테라퓨틱스, 인크. Gabaa 양성 알로스테릭 조절제 화합물, 이의 제조 방법 및 용도
IL281335B2 (en) 2018-09-13 2024-07-01 Saniona As A gabaa receptor ligand
HU231223B1 (hu) 2018-09-28 2022-01-28 Richter Gedeon Nyrt. GABAA A5 receptor modulátor hatású biciklusos vegyületek
EP4126858A1 (en) 2020-03-26 2023-02-08 Richter Gedeon Nyrt. Dihydro-2-pyrrolo[3,4-c]pyridine derivatives as gabaa a5 receptor modulators
WO2025141131A1 (en) 2023-12-27 2025-07-03 Saniona A/S A gabaa receptor ligand and the use thereof in medicine, in particular in the treatment of epilepsy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2194205T3 (es) * 1996-07-25 2003-11-16 Merck Sharp & Dohme Derivados de triazolo-piridazina sustituidos como ligandos para los receptores gaba.

Also Published As

Publication number Publication date
EA200100071A1 (ru) 2001-06-25
IL139775A0 (en) 2002-02-10
PE20000710A1 (es) 2000-08-14
SK285307B6 (sk) 2006-10-05
NO20006576D0 (no) 2000-12-21
DE69907675D1 (de) 2003-06-12
CZ291409B6 (cs) 2003-03-12
HRP20000879A2 (en) 2001-06-30
JP2002518501A (ja) 2002-06-25
AR018925A1 (es) 2001-12-12
BR9911563A (pt) 2001-03-20
EA003332B1 (ru) 2003-04-24
AU4630199A (en) 2000-01-10
BG105152A (en) 2001-10-31
EP1090004B1 (en) 2003-05-07
CA2335328A1 (en) 1999-12-29
AU757315B2 (en) 2003-02-13
CN1138779C (zh) 2004-02-18
EE200000767A (et) 2002-06-17
DE69907675T2 (de) 2004-03-04
YU77800A (sh) 2003-10-31
CZ20004872A3 (cs) 2001-07-11
CA2335328C (en) 2007-11-27
RS49746B (sr) 2008-04-04
US6630471B1 (en) 2003-10-07
ES2196824T3 (es) 2003-12-16
TWI222449B (en) 2004-10-21
SK19552000A3 (sk) 2001-08-06
BG64989B1 (bg) 2006-11-30
ZA200007485B (en) 2002-01-07
WO1999067245A1 (en) 1999-12-29
PL204650B1 (pl) 2010-01-29
EP1090004A1 (en) 2001-04-11
GEP20033143B (en) 2003-12-25
NO317992B1 (no) 2005-01-17
ID27771A (id) 2001-04-26
JP4749545B2 (ja) 2011-08-17
PL345332A1 (en) 2001-12-17
IL139775A (en) 2007-02-11
MY124341A (en) 2006-06-30
HUP0102894A2 (hu) 2001-11-28
CN1307579A (zh) 2001-08-08
CO5031239A1 (es) 2001-04-27
ATE239730T1 (de) 2003-05-15
NZ508290A (en) 2003-09-26
IS5730A (is) 2000-11-24
HUP0102894A3 (en) 2003-03-28
IS2258B (is) 2007-06-15
KR100604108B1 (ko) 2006-07-26
KR20010053136A (ko) 2001-06-25
GB9813576D0 (en) 1998-08-19
TR200003789T2 (tr) 2001-04-20

Similar Documents

Publication Publication Date Title
IS4644A (is) Setin bensýlamínópíperidín efnasambönd og lyfjablöndur þeirra
NO20014219D0 (no) <Kappa>-agonist-forbindelser og farmasöytiske preparater derav
NO20021401D0 (no) Konazolinforbindelser og farmasöytiske preparater inneholdende slike forbindelser
IS5070A (is) Nýtt form S-handhverfu ómeprasóls og lyfjablöndursem innihalda það
IS5953A (is) Lyfjablöndur úr örgerðum eplerenonum
NO20016277D0 (no) Systemer og fremgangsmåter for aerolisering av farmasöytiske formuleringer
EE04904B1 (et) Tiobensimidasooli derivaadid ja farmatseutiline kompositsioon
NO965539D0 (no) Farmasöytiske tacrinepreparater
BR9610153A (pt) Formulações farmacêuticas
BR9611626A (pt) Formulações farmacéuticas
ATE187063T1 (de) Arzneimittel
PT869126E (pt) Derivados de ditiolano, sua preparacao e seus efeitos terapeuticos
DE69530325D1 (de) Aerosol-arzneiformulierungen
NO20011157D0 (no) Benzenderivater og farmasøytisk anvendelse derav
ATE367150T1 (de) Arzneimittel
NO20006576D0 (no) Et substituert triazol-pyridazinderivat og farmasöytiske preparater fremstilt av dette
NO961274D0 (no) Azolderivat og farmasöytiske preparat derav
NO994659D0 (no) Nye pyridinderivater og farmasöytiske preparater inneholdende slike
ID16781A (id) Formulasi-formulasi farmasi
DE69926012D1 (de) Arzneizubereitungen
NO973980D0 (no) Imiadazolderivater og medisinsk preparat
ITMI941169A0 (it) Formulazioni farmaceutiche
DK1066261T3 (da) Pyridinderivat og farmaceutisk præparat indeholdende samme
NO994764D0 (no) Nye pyridinderivater og farmasöytiske preparater inneholdende disse
DE69906934D1 (de) Arzneizubereitungen

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees