NO20000700D0 - Interleukin-18-proteiner samt fremstilling og anvendelse derav - Google Patents

Interleukin-18-proteiner samt fremstilling og anvendelse derav

Info

Publication number: NO20000700D0
Authority: NO; Norway
Prior art keywords: interleukin; proteins; preparation
Prior art date: 1997-08-14

Application number

NO20000700A

Other languages

English (en)

Other versions

NO327240B1 (no

NO20000700L (no

Inventor

Daniela Novick

Charles Dinarello

Menachem Rubinstein

Soo Hyun Kim

Original Assignee

Yeda Res & Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-08-14

Filing date

2000-02-11

Publication date

2000-02-11

1997-08-14 Priority claimed from IL12155497A external-priority patent/IL121554A0/xx

1997-08-27 Priority claimed from IL12163997A external-priority patent/IL121639A0/xx

2000-02-11 Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev

2000-02-11 Publication of NO20000700D0 publication Critical patent/NO20000700D0/no

2000-04-14 Publication of NO20000700L publication Critical patent/NO20000700L/no

2009-05-18 Publication of NO327240B1 publication Critical patent/NO327240B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/826—Viruses
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/834—Urine; urinary system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Diabetes (AREA)
Cell Biology (AREA)
Urology & Nephrology (AREA)
Orthopedic Medicine & Surgery (AREA)
Neurosurgery (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Neurology (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Transplantation (AREA)

NO20000700A 1997-08-14 2000-02-11 Interleukin-18-bindende protein, DNA som koder for dette, vektor og celle inneholdende slikt DNA, fremgangsmate for fremstilling av proteinet, antistoffer som reagerer mot proteinet samt anvendelse av proteinet for fremstilling av medikamenter. NO327240B1 (no)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
IL12155497A IL121554A0 (en)	1997-08-14	1997-08-14	Interleukin-18 binding proteins their preparation and use
IL12163997A IL121639A0 (en)	1997-08-14	1997-08-27	Interleukin-18 binding proteins their preparation and use
IL12186097A IL121860A0 (en)	1997-08-14	1997-09-29	Interleukin-18 binding proteins their preparation and use
IL12213497A IL122134A0 (en)	1997-08-14	1997-11-06	Interleukin-18 binding proteins their preparation and use
IL12546398A IL125463A0 (en)	1997-08-14	1998-07-22	Interleukin-18 binding proteins their preparation and use
PCT/IL1998/000379 WO1999009063A1 (en)	1997-08-14	1998-08-13	Interleukin-18 binding proteins, their preparation and use

Publications (3)

Publication Number	Publication Date
NO20000700D0 true NO20000700D0 (no)	2000-02-11
NO20000700L NO20000700L (no)	2000-04-14
NO327240B1 NO327240B1 (no)	2009-05-18

Family

ID=27517687

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20000700A NO327240B1 (no)	1997-08-14	2000-02-11	Interleukin-18-bindende protein, DNA som koder for dette, vektor og celle inneholdende slikt DNA, fremgangsmate for fremstilling av proteinet, antistoffer som reagerer mot proteinet samt anvendelse av proteinet for fremstilling av medikamenter.

Country Status (28)

Country	Link
US (4)	US6605280B1 (no)
EP (1)	EP1003781B1 (no)
JP (1)	JP4272348B2 (no)
KR (1)	KR100687388B1 (no)
CN (1)	CN1243021C (no)
AR (2)	AR013422A1 (no)
AT (1)	ATE443719T1 (no)
AU (1)	AU755794B2 (no)
BG (1)	BG65519B1 (no)
BR (1)	BRPI9811940B8 (no)
CA (1)	CA2298855C (no)
CY (1)	CY1109664T1 (no)
CZ (1)	CZ300818B6 (no)
DE (2)	DE69841175D1 (no)
DK (1)	DK1003781T3 (no)
EA (1)	EA003675B1 (no)
EE (1)	EE05538B1 (no)
ES (1)	ES2149149T3 (no)
HU (1)	HU226698B1 (no)
IL (5)	IL121860A0 (no)
NO (1)	NO327240B1 (no)
NZ (1)	NZ502392A (no)
PL (1)	PL206070B1 (no)
PT (1)	PT1003781E (no)
SI (1)	SI1003781T1 (no)
SK (1)	SK287194B6 (no)
UA (1)	UA75862C2 (no)
WO (1)	WO1999009063A1 (no)

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JP2006508056A (ja)	2002-08-28	2006-03-09	イミュネックス・コーポレーション	心臓血管疾患を治療するための組成物および方法
EP1572291B1 (en) *	2002-10-08	2013-04-03	Ares Trading S.A.	The use of cytokine able to bind il-18bp and of inhibiting the activity of a second cytokine
IL152232A0 (en) *	2002-10-10	2003-05-29	Yeda Res & Dev	Promoter to il-18bp, its preparation and use
KR100988129B1 (ko)	2003-04-30	2010-10-18	쥬리디컬 파운데이션 더 케모-세로-쎄라퓨틱 리서치 인스티튜트	인간 항인간 인터루킨-18 항체와 그 단편, 및 이들의이용방법
US20080076708A1 (en) *	2003-05-13	2008-03-27	Valter Altarocca	Active Variants of the Il-18 Binding Protein and Medical Uses Thereof
DK1689777T3 (da)	2003-11-05	2007-06-11	Ares Trading Sa	Fremgangsmåde til oprensning af il18-bindende protein
US7968684B2 (en)	2003-11-12	2011-06-28	Abbott Laboratories	IL-18 binding proteins
BRPI0416467A (pt) *	2003-11-12	2007-03-06	Univ Colorado Regents	ácido nucléico purificado, célula hospedeira, proteìna purificada, anticorpo, fragmento fab, e, métodos para induzir a produção de tnf alfa, para tratar um paciente, e para triagem para inibidores da il-32
US20050100965A1 (en)	2003-11-12	2005-05-12	Tariq Ghayur	IL-18 binding proteins
IL159670A0 (en) *	2003-12-31	2004-06-01	Yeda Res & Dev	Use of il-18 binding protein in inflammations
DK1720979T3 (da) *	2004-03-01	2007-12-10	Ares Trading Sa	Anvendelse af et serumfrit celledyrkningsmedium til fremstilling af IL-18BP I pattedyrceller
WO2005097998A2 (en) *	2004-03-31	2005-10-20	Regeneron Pharmaceuticals, Inc.	Il-18 specific polypeptides and therapeutic uses thereof
DE602005009827D1 (de) *	2004-06-29	2008-10-30	Ares Trading Sa	Verfahren zur aufreinigung von il-18-bindendem protein
SI1888100T1 (sl) *	2005-06-03	2012-01-31	Merck Serono Sa	Uporaba izooblik il-18pb za zdravljenje in/ali prepreäśevanje nevroloĺ kih vnetnih bolezni
PL1885753T3 (pl) *	2005-06-03	2011-12-30	Ares Trading Sa	Wytwarzanie rekombinowanego białka wiążącego IL-18
ATE529433T1 (de) *	2005-06-10	2011-11-15	Ares Trading Sa	Verfahren zur reinigung eines il-18-bindenden proteins
CN101003812B (zh) *	2006-01-17	2011-01-05	温州医学院	一种用于制备重组人egf-il18融合蛋白的方法
CA2652733C (en)	2006-05-25	2016-06-21	Glaxo Group Limited	Modified humanised anti-interleukin-18 antibodies
WO2010040736A2 (en) *	2008-10-07	2010-04-15	Ablynx Nv	Amino acid sequences directed against il18 and/or the il-18 receptor and polypeptides comprising the same for the treatment of diseases and/or disorders associated with il-18 mediated signaling
CA2897067A1 (en) *	2013-01-02	2014-07-10	Wilsa, Inc.	Method and apparatus for conditioning fluids
KR102321172B1 (ko) *	2013-09-05	2021-11-05	에이비2 바이오 에스에이	염증성 질환에서 il-18 결합 단백질(ｉｌ-18ｂｐ)
CA2972689A1 (en)	2015-03-05	2016-09-09	Ab2 Bio Sa	Il-18 binding protein (il-18bp) and antibodies in inflammatory diseases
EP3943097A1 (en)	2020-07-24	2022-01-26	AB2 Bio SA	Car-t cell therapy
CN120737196A (zh) *	2022-01-28	2025-10-03	和径医药科技（上海）有限公司	一种靶向il-18bp的抗体及其应用
IL314346A (en) *	2022-03-15	2024-09-01	Compugen Ltd	Antibodies antagonistic to IL-18BP and their use in monotherapy and combination therapy in cancer treatment
CN114605521A (zh) *	2022-04-06	2022-06-10	内蒙古农业大学	一种细胞免疫调节蛋白及其应用
CN114891125B (zh) *	2022-06-16	2023-04-11	广东医科大学	一种长效重组白细胞介素-18结合蛋白及其生产方法与应用
KR20250133728A (ko)	2023-01-06	2025-09-08	라센 테라퓨틱스, 인코포레이티드	항-il-18bp 항체
TW202515608A (zh)	2023-06-26	2025-04-16	以色列商坎布根有限公司	Ｉｌ—１８ｂｐ拮抗抗體及其於癌症治療之單一療法及組合療法的用途

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1997
- 1997-09-29 IL IL12186097A patent/IL121860A0/xx unknown
- 1997-11-06 IL IL12213497A patent/IL122134A0/xx unknown
1998
- 1998-07-22 IL IL12546398A patent/IL125463A0/xx unknown
- 1998-08-13 AU AU87460/98A patent/AU755794B2/en not_active Expired
- 1998-08-13 DK DK98938877.2T patent/DK1003781T3/da active
- 1998-08-13 ES ES98938877T patent/ES2149149T3/es not_active Expired - Lifetime
- 1998-08-13 WO PCT/IL1998/000379 patent/WO1999009063A1/en not_active Ceased
- 1998-08-13 NZ NZ502392A patent/NZ502392A/xx not_active IP Right Cessation
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- 1998-08-13 JP JP2000509740A patent/JP4272348B2/ja not_active Expired - Lifetime
- 1998-08-13 AT AT98938877T patent/ATE443719T1/de active
- 1998-08-13 CN CNB988081342A patent/CN1243021C/zh not_active Expired - Lifetime
- 1998-08-13 CZ CZ20000490A patent/CZ300818B6/cs not_active IP Right Cessation
- 1998-08-13 US US09/485,632 patent/US6605280B1/en not_active Expired - Lifetime
- 1998-08-13 UA UA2000031437A patent/UA75862C2/uk unknown
- 1998-08-13 PL PL338647A patent/PL206070B1/pl unknown
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- 1998-08-13 EA EA200000216A patent/EA003675B1/ru not_active IP Right Cessation
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- 1998-08-13 BR BRPI9811940 patent/BRPI9811940B8/pt not_active IP Right Cessation
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- 1998-08-13 KR KR1020007001504A patent/KR100687388B1/ko not_active Expired - Lifetime
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- 1998-08-13 DE DE1003781T patent/DE1003781T1/de active Pending
- 1998-08-14 AR ARP980104054A patent/AR013422A1/es active IP Right Grant
2000
- 2000-02-10 BG BG104149A patent/BG65519B1/bg unknown
- 2000-02-11 NO NO20000700A patent/NO327240B1/no not_active IP Right Cessation
- 2000-02-13 IL IL134523A patent/IL134523A/en not_active IP Right Cessation
2003
- 2003-05-08 US US10/434,583 patent/US7101689B2/en not_active Expired - Lifetime
2006
- 2006-03-15 US US11/376,794 patent/US7799541B2/en not_active Expired - Fee Related
2007
- 2007-09-17 AR ARP070104104A patent/AR062867A2/es not_active Application Discontinuation
2009
- 2009-07-29 US US12/511,756 patent/US8436148B2/en not_active Expired - Fee Related
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Also Published As

Publication number	Publication date
AR013422A1 (es)	2000-12-27
BG104149A (bg)	2000-08-31
SK287194B6 (sk)	2010-03-08
CA2298855C (en)	2014-05-27
KR20010022900A (ko)	2001-03-26
BRPI9811940B1 (pt)	2011-10-04
CY1109664T1 (el)	2014-08-13
US6605280B1 (en)	2003-08-12
IL134523A0 (en)	2001-04-30
ES2149149T1 (es)	2000-11-01
ES2149149T3 (es)	2009-12-01
WO1999009063A1 (en)	1999-02-25
US20100010200A1 (en)	2010-01-14
EE05538B1 (et)	2012-04-16
CN1243021C (zh)	2006-02-22
EA200000216A1 (ru)	2000-08-28
US7101689B2 (en)	2006-09-05
IL134523A (en)	2011-09-27
EE200000073A (no)	2000-10-16
HU226698B1 (en)	2009-07-28
BG65519B1 (bg)	2008-10-31
BRPI9811940B8 (pt)	2021-07-06
US20040037829A1 (en)	2004-02-26
NO327240B1 (no)	2009-05-18
CN1267307A (zh)	2000-09-20
PT1003781E (pt)	2009-10-26
PL206070B1 (pl)	2010-06-30
KR100687388B1 (ko)	2007-02-26
IL121860A0 (en)	1998-02-22
DE1003781T1 (de)	2001-01-11
JP4272348B2 (ja)	2009-06-03
AR062867A2 (es)	2008-12-10
HUP0003533A2 (hu)	2001-01-29
EA003675B1 (ru)	2003-08-28
IL122134A0 (en)	1998-04-05
PL338647A1 (en)	2000-11-06
US7799541B2 (en)	2010-09-21
EP1003781B1 (en)	2009-09-23
IL125463A0 (en)	1999-03-12
US8436148B2 (en)	2013-05-07
AU8746098A (en)	1999-03-08
BRPI9811940A (pt)	2000-09-05
US20060154294A1 (en)	2006-07-13
UA75862C2 (uk)	2006-06-15
NZ502392A (en)	2002-12-20
SK1762000A3 (en)	2000-09-12
ATE443719T1 (de)	2009-10-15
NO20000700L (no)	2000-04-14
AU755794B2 (en)	2002-12-19
DE69841175D1 (de)	2009-11-05
CZ2000490A3 (cs)	2000-08-16
CA2298855A1 (en)	1999-02-25
EP1003781A1 (en)	2000-05-31
JP2001514876A (ja)	2001-09-18
DK1003781T3 (da)	2010-01-25
HUP0003533A3 (en)	2003-08-28
CZ300818B6 (cs)	2009-08-19
SI1003781T1 (sl)	2009-12-31
HK1028773A1 (en)	2001-03-02

Publication	Publication Date	Title
NO20000700D0 (no)	2000-02-11	Interleukin-18-proteiner samt fremstilling og anvendelse derav
NO983364L (no)	1999-01-25	Konsensusproteiner
IS5375A (is)	2000-02-11	KAY-nýstárlegt ónæmisprótín
IS4496A (is)	1997-06-04	Úðablöndur úr peptíðum og próteinum
NO20071415L (no)	1999-08-19	OB-fusjonsproteinpreparater og fremgangsmater
DE69839603D1 (de)	2008-07-24	Zierenden proteins
NO963371D0 (no)	1996-08-13	Hematopoeseprotein samt materialer og fremgangsmåter for fremstilling av det
DE69828330D1 (de)	2005-02-03	Aktiviertes Protein C Formulierungen
DK0921796T3 (da)	2001-07-16	Tetrahydrolipstatinholdige præparater
DE69735926D1 (de)	2006-06-29	Interleukin-18 Rezeptorproteine
ID24289A (id)	2000-07-13	Benzotiazol inhibitor-inhibitor protein terosin kinase
NO20002990L (no)	2000-08-08	Nytt overflateprotein
DK0941056T3 (da)	2002-07-15	Sphingomyelinasepræparater samt anvendelse deraf
FI970979A7 (fi)	1997-03-07	Muokatut ihmisen C3-proteiinit
DK0779035T3 (da)	2003-01-20	Modificeret valleprotein
NO971505D0 (no)	1997-04-03	Trofinin og trofininhjelperproteiner
DE69705017D1 (de)	2001-07-05	Medikamente bindendes Protein
EP1018551A4 (en)	2003-07-23	MEGSIN PROTEIN
ID21034A (id)	1999-04-08	Protein kinase dan penggunaannya
DE69837507D1 (de)	2007-05-24	Humanes Hedgehog-Protein
TR199701666A3 (tr)	1999-10-21	Sismanliga karsi proteinler
NO20005547D0 (no)	2000-11-03	Myelinbasiske proteinpeptider og anvendelser derav
KR960010685A (ko)	1996-04-20	펩티드 및 그 용도
SE9701041D0 (sv)	1997-03-21	Novel proteins and their use
NO20006091D0 (no)	2000-11-30	Humant protein C-polypeptid

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