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NL1025069A1 - Aanvaardbaar niet-hygroscopisch tussenproduct van een preparaat dat een hygroscopisch geneesmiddel bevat. - Google Patents

Aanvaardbaar niet-hygroscopisch tussenproduct van een preparaat dat een hygroscopisch geneesmiddel bevat.

Info

Publication number
NL1025069A1
NL1025069A1 NL1025069A NL1025069A NL1025069A1 NL 1025069 A1 NL1025069 A1 NL 1025069A1 NL 1025069 A NL1025069 A NL 1025069A NL 1025069 A NL1025069 A NL 1025069A NL 1025069 A1 NL1025069 A1 NL 1025069A1
Authority
NL
Netherlands
Prior art keywords
hygroscopic
preparation containing
acceptable non
drug
hygroscopic drug
Prior art date
Application number
NL1025069A
Other languages
English (en)
Other versions
NL1025069C2 (nl
Inventor
Danchen Gao
Ann M Czyzewski
Jay Sanjay Trivedi
Rajeev Dattatreya Gokhale
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of NL1025069A1 publication Critical patent/NL1025069A1/nl
Application granted granted Critical
Publication of NL1025069C2 publication Critical patent/NL1025069C2/nl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
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    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
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    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
NL1025069A 2002-12-19 2003-12-18 Aanvaardbaar niet-hygroscopisch tussenproduct van een preparaat dat een hygroscopisch geneesmiddel bevat. NL1025069C2 (nl)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US43514702P 2002-12-19 2002-12-19
US43502202P 2002-12-19 2002-12-19
US43542202P 2002-12-19 2002-12-19
US43502202 2002-12-19
US43514702 2002-12-19
US43542202 2002-12-19

Publications (2)

Publication Number Publication Date
NL1025069A1 true NL1025069A1 (nl) 2004-07-01
NL1025069C2 NL1025069C2 (nl) 2005-02-16

Family

ID=32719157

Family Applications (1)

Application Number Title Priority Date Filing Date
NL1025069A NL1025069C2 (nl) 2002-12-19 2003-12-18 Aanvaardbaar niet-hygroscopisch tussenproduct van een preparaat dat een hygroscopisch geneesmiddel bevat.

Country Status (17)

Country Link
US (2) US20050013856A1 (nl)
EP (2) EP1575563B1 (nl)
JP (2) JP2006513238A (nl)
AR (2) AR042511A1 (nl)
AT (1) ATE353633T1 (nl)
AU (2) AU2003298010A1 (nl)
BR (2) BR0317392A (nl)
CA (2) CA2511385A1 (nl)
DE (1) DE60311875T2 (nl)
ES (1) ES2280835T3 (nl)
HN (1) HN2003000417A (nl)
MX (2) MXPA05006802A (nl)
NL (1) NL1025069C2 (nl)
PE (1) PE20040972A1 (nl)
TW (2) TW200423971A (nl)
UY (1) UY28138A1 (nl)
WO (2) WO2004060352A1 (nl)

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AR042511A1 (es) 2005-06-22
MXPA05005667A (es) 2005-07-26
DE60311875D1 (de) 2007-03-29
UY28138A1 (es) 2004-08-31
WO2004060353A1 (en) 2004-07-22
EP1575563A1 (en) 2005-09-21
AU2003298010A1 (en) 2004-07-29
ES2280835T3 (es) 2007-09-16
ATE353633T1 (de) 2007-03-15
AU2003296948A1 (en) 2004-07-29
HN2003000417A (es) 2005-11-01
WO2004060352A8 (en) 2005-09-15
US20040197411A1 (en) 2004-10-07
NL1025069C2 (nl) 2005-02-16
EP1575564A1 (en) 2005-09-21
MXPA05006802A (es) 2005-09-08
CA2509261A1 (en) 2004-07-22
CA2511385A1 (en) 2004-07-22
DE60311875T2 (de) 2007-08-30
TW200423971A (en) 2004-11-16
PE20040972A1 (es) 2004-12-14
BR0317392A (pt) 2005-12-20
TW200413006A (en) 2004-08-01
WO2004060353A9 (en) 2004-10-07
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JP2006513238A (ja) 2006-04-20
WO2004060352A1 (en) 2004-07-22

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