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MY8700184A - 6 7-benzomorphan derivatives processes for their production pharmaceutical compositions containing said derivatives and their use as pharmaceuticals - Google Patents

6 7-benzomorphan derivatives processes for their production pharmaceutical compositions containing said derivatives and their use as pharmaceuticals

Info

Publication number
MY8700184A
MY8700184A MY184/87A MY8700184A MY8700184A MY 8700184 A MY8700184 A MY 8700184A MY 184/87 A MY184/87 A MY 184/87A MY 8700184 A MY8700184 A MY 8700184A MY 8700184 A MY8700184 A MY 8700184A
Authority
MY
Malaysia
Prior art keywords
derivatives
hydrogen
pharmaceuticals
pharmaceutical compositions
compositions containing
Prior art date
Application number
MY184/87A
Other languages
English (en)
Inventor
Anthony Marie Dr Akkerman
Hermanus C C K Van Dr Bakel
Roelof Christian Klaas Smit
Hendricus Bernardus Anto Welle
Magda Dr Marko
Original Assignee
Acf Chemiefarma Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acf Chemiefarma Nv filed Critical Acf Chemiefarma Nv
Publication of MY8700184A publication Critical patent/MY8700184A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrrole Compounds (AREA)
MY184/87A 1979-10-23 1987-12-30 6 7-benzomorphan derivatives processes for their production pharmaceutical compositions containing said derivatives and their use as pharmaceuticals MY8700184A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7907800A NL7907800A (nl) 1979-10-23 1979-10-23 Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan, farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werkwijze voor het bereiden van deze verbindingen en de farmaceutische preparaten.

Publications (1)

Publication Number Publication Date
MY8700184A true MY8700184A (en) 1987-12-31

Family

ID=19834064

Family Applications (1)

Application Number Title Priority Date Filing Date
MY184/87A MY8700184A (en) 1979-10-23 1987-12-30 6 7-benzomorphan derivatives processes for their production pharmaceutical compositions containing said derivatives and their use as pharmaceuticals

Country Status (17)

Country Link
US (2) US4425353A (fi)
EP (1) EP0028717B1 (fi)
JP (1) JPS5686164A (fi)
AT (1) ATE8990T1 (fi)
AU (1) AU539310B2 (fi)
CA (1) CA1155840A (fi)
DE (1) DE3068961D1 (fi)
DK (1) DK435380A (fi)
ES (1) ES496167A0 (fi)
FI (1) FI67373C (fi)
IE (1) IE50667B1 (fi)
IL (1) IL61324A (fi)
MY (1) MY8700184A (fi)
NL (1) NL7907800A (fi)
NZ (1) NZ195329A (fi)
PT (1) PT71949B (fi)
ZA (1) ZA806528B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4579950A (en) * 1982-08-20 1986-04-01 Hoechst-Roussel Pharmaceuticals Inc. Intermediates for spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine] compounds
JPH01102077A (ja) * 1987-09-24 1989-04-19 Hoechst Roussel Pharmaceut Inc ２，６‐メタノピロロ‐３‐ベンズアゾジン類
DE4121821A1 (de) * 1991-07-02 1993-01-14 Boehringer Ingelheim Kg Neue benzomorphane und ihre verwendung als arzneimittel
DE19528472A1 (de) * 1995-08-03 1997-02-06 Boehringer Ingelheim Kg Neues Verfahren zur Herstellung von Norbenzomorphan einer Zwischenstufe bei Herstellung von pharmazeutisch wertvollen Benzomorphanderivaten, insbesondere von (-)-(1R,5S,S"R)-3'-Hydroxy-2-(2-methoxypropyl-)-5,9,9-trimethyl-6,7 benzomorphan
AU9621598A (en) 1997-10-20 1999-05-10 Novo Nordisk A/S Luteinising hormone antagonists useful for treatment of estrogen deficiencies, or as a contraceptive
US6136980A (en) * 1998-05-01 2000-10-24 Boehringer Ingelheim Kg Method of preparing norbenzomorphane as an intermediate in the preparation of pharmaceutically useful benzomorphane derivatives, in particular (-)-(1R,5S,2"R)-3'-hydroxy-2-(2-methoxypropyl)-5,9,9-trimethyl-6,7-benzo morphane
EP1225901A2 (en) * 1999-09-21 2002-07-31 Emory University Uses and compositions for treating platelet-related disorders using anagrelide
US6495694B2 (en) * 2000-06-16 2002-12-17 Boehringer Ingelheim Pharma Kg Efficient separation of enantiomers of piperidone derivatives by precipitation of the desired eantiomer during in situ racemization of the unwanted enantiomer
CA2870605A1 (en) 2012-05-11 2013-11-14 Purdue Pharma L.P. Benzomorphan compounds as opioid receptors modulators
US10138207B2 (en) 2012-11-09 2018-11-27 Purdue Pharma, L.P. Benzomorphan analogs and the use thereof
EP2951160B1 (en) 2013-01-31 2019-04-24 Purdue Pharma LP Benzomorphan analogs and the use thereof
WO2015171553A1 (en) 2014-05-06 2015-11-12 Purdue Pharma L.P. Benzomorphan analogs and use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL130089C (fi) 1963-11-07
US4087532A (en) 1974-03-09 1978-05-02 Boehringer Ingelheim Gmbh Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
GB1513961A (en) * 1975-02-25 1978-06-14 Acf Chemiefarma Nv 6,7-benzomorphans method for their preparation and intermediates
DE2716687A1 (de) 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
US4202897A (en) * 1977-07-25 1980-05-13 Sandoz, Inc. Prolactin secretion inhibitors
IT8049377A0 (it) 1979-08-03 1980-07-30 Sandoz Ag Medicamento a base di composti triciclici per inibire la secrezione dell'ormone luteinizzante(caso 1005224)

Also Published As

Publication number Publication date
CA1155840A (en) 1983-10-25
IL61324A0 (en) 1980-12-31
AU6354080A (en) 1981-04-30
FI67373C (fi) 1985-03-11
US4425353A (en) 1984-01-10
EP0028717A1 (en) 1981-05-20
IL61324A (en) 1985-03-31
FI67373B (fi) 1984-11-30
PT71949B (en) 1981-12-17
DK435380A (da) 1981-04-24
AU539310B2 (en) 1984-09-20
NL7907800A (nl) 1981-04-27
ES8106894A1 (es) 1981-09-16
ZA806528B (en) 1982-06-30
FI803237L (fi) 1981-04-24
NZ195329A (en) 1984-05-31
IE50667B1 (en) 1986-06-11
EP0028717B1 (en) 1984-08-15
PT71949A (en) 1981-08-19
DE3068961D1 (en) 1984-09-20
ATE8990T1 (de) 1984-09-15
US4406904A (en) 1983-09-27
JPS5686164A (en) 1981-07-13
IE802188L (en) 1981-04-23
ES496167A0 (es) 1981-09-16

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