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MXPA02011218A - Composiciones y metodos para el tratamiento de cancer. - Google Patents

Composiciones y metodos para el tratamiento de cancer.

Info

Publication number
MXPA02011218A
MXPA02011218A MXPA02011218A MXPA02011218A MXPA02011218A MX PA02011218 A MXPA02011218 A MX PA02011218A MX PA02011218 A MXPA02011218 A MX PA02011218A MX PA02011218 A MXPA02011218 A MX PA02011218A MX PA02011218 A MXPA02011218 A MX PA02011218A
Authority
MX
Mexico
Prior art keywords
thalidomide
cancer
treatment
methods
administration
Prior art date
Application number
MXPA02011218A
Other languages
English (en)
Inventor
Sol Barer
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of MXPA02011218A publication Critical patent/MXPA02011218A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Esta invencion se refiere a las composiciones que contienen talidomida y otro medicamento anti-cancer que puede utilizarse en el tratamiento o prevencion de cancer. Los medicamentos anti-cancer preferidos son inhibidores de la topoisomerasa. Una composicion particular contiene talidomida, o una sal, solvato o clatrato farmaceuticamente aceptable de este, e irinotecano. La invencion tambien se refiere a los metodos de tratamiento o prevencion de cancer que consisten en la administracion de un medicamento talidomida y otro medicamento anti-cancer a un paciente en necesidad de un tratamiento o prevencion como este. La invencion ademas se refiere a los metodos para reducir o evitar efectos colaterales adversos asociados con la administracion de quimioterapia o radioterapia, que consisten en la administracion de talidomida a un paciente en necesidad de tal reduccion o evitacion.
MXPA02011218A 2000-05-15 2001-05-10 Composiciones y metodos para el tratamiento de cancer. MXPA02011218A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20414300P 2000-05-15 2000-05-15
PCT/US2001/015327 WO2001087307A2 (en) 2000-05-15 2001-05-10 Compositions and methods for the treatment of cancer

Publications (1)

Publication Number Publication Date
MXPA02011218A true MXPA02011218A (es) 2004-08-19

Family

ID=22756804

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02011218A MXPA02011218A (es) 2000-05-15 2001-05-10 Composiciones y metodos para el tratamiento de cancer.

Country Status (18)

Country Link
US (2) US7435726B2 (es)
EP (1) EP1307197B1 (es)
JP (1) JP5409981B2 (es)
KR (1) KR100790589B1 (es)
AR (1) AR029084A1 (es)
AT (1) ATE322266T1 (es)
AU (2) AU6147401A (es)
BR (1) BR0110877A (es)
CA (1) CA2408707C (es)
DE (1) DE60118571T2 (es)
DK (1) DK1307197T3 (es)
ES (1) ES2258084T3 (es)
MX (1) MXPA02011218A (es)
NZ (1) NZ522767A (es)
PT (1) PT1307197E (es)
TW (1) TWI289449B (es)
WO (1) WO2001087307A2 (es)
ZA (1) ZA200209638B (es)

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JP2003533484A (ja) 2003-11-11
AU6147401A (en) 2001-11-26
AR029084A1 (es) 2003-06-04
ZA200209638B (en) 2003-11-27
DE60118571T2 (de) 2007-02-01
ES2258084T3 (es) 2006-08-16
KR100790589B1 (ko) 2008-01-02
EP1307197A2 (en) 2003-05-07
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US7435726B2 (en) 2008-10-14
JP5409981B2 (ja) 2014-02-05
WO2001087307A3 (en) 2002-07-25
US20020035090A1 (en) 2002-03-21
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BR0110877A (pt) 2003-03-11
AU2001261474B2 (en) 2006-03-09
TWI289449B (en) 2007-11-11
PT1307197E (pt) 2006-08-31
EP1307197B1 (en) 2006-04-05
US20050148524A1 (en) 2005-07-07
HK1054502A1 (en) 2003-12-05
DE60118571D1 (de) 2006-05-18
WO2001087307A2 (en) 2001-11-22

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