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MX9706187A - Derivados de 3-pirrolidiliden-2-ona-cefalosporinas. - Google Patents

Derivados de 3-pirrolidiliden-2-ona-cefalosporinas.

Info

Publication number
MX9706187A
MX9706187A MX9706187A MX9706187A MX9706187A MX 9706187 A MX9706187 A MX 9706187A MX 9706187 A MX9706187 A MX 9706187A MX 9706187 A MX9706187 A MX 9706187A MX 9706187 A MX9706187 A MX 9706187A
Authority
MX
Mexico
Prior art keywords
lower alkyl
hydrogen
formula
derivatives
pyrrolidylidene
Prior art date
Application number
MX9706187A
Other languages
English (en)
Other versions
MXPA97006187A (es
Inventor
Ingrid Heinze-Krauss
Hans Richter
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX9706187A publication Critical patent/MX9706187A/es
Publication of MXPA97006187A publication Critical patent/MXPA97006187A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Los derivados de cefalosporina de formula general I (Ver Formula) donde R1 es hidrogeno, alquilo inferior, aralquilo, cicloalquilo, R3CO- o -C(R4R5)CO2R6; donde R4 y R5 son cada uno independientemente hidrogeno o alquilo inferior o R4 y R5 tomados conjuntamente forman un grupo cicloalquilo; R3 es hidrogeno o alquilo inferior y R6 es hidrogeno, alquilo inferior, alquenilo inferior o un grupo protector de ácido carboxílico, R2 es isobutilo, 2,2-dimetil-propilo o ciclohexil-metilo; n es 0, 1 o 2; X es CH o N; así como también sus esteres fácilmente hidrolizables de los mismos, las sales aceptables farmacéuticamente de los compuestos antes mencionados e hidratos de los compuestos de formula (I) y sus esteres y sales.
MXPA/A/1997/006187A 1995-02-27 1997-08-13 Derivados de 3-pirrolidiliden-2-ona-cefalosporinas MXPA97006187A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP95102742.4 1995-02-27
EP95102742 1995-02-27
PCT/EP1996/000667 WO1996026943A1 (en) 1995-02-27 1996-02-16 Derivatives of 3-pyrrolidylidene-2-one-cephalosporines

Publications (2)

Publication Number Publication Date
MX9706187A true MX9706187A (es) 1997-11-29
MXPA97006187A MXPA97006187A (es) 1998-07-03

Family

ID=

Also Published As

Publication number Publication date
EP0812323A1 (en) 1997-12-17
WO1996026943A1 (en) 1996-09-06
TR199700859T1 (xx) 1998-02-21
AR003927A1 (es) 1998-09-30
BR9607046A (pt) 1997-12-30
CN1176641A (zh) 1998-03-18
US5925632A (en) 1999-07-20
FI973500A7 (fi) 1997-08-26
CA2212345A1 (en) 1996-09-06
AU4877196A (en) 1996-09-18
FI973500A0 (fi) 1997-08-26
JPH11501017A (ja) 1999-01-26
FI973500L (fi) 1997-08-26

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