MX9702011A - Mocrioorganismos y metodos para la sobreproduccion de dahp mediante el gen pps clonado. - Google Patents
Mocrioorganismos y metodos para la sobreproduccion de dahp mediante el gen pps clonado.Info
- Publication number
- MX9702011A MX9702011A MX9702011A MX9702011A MX9702011A MX 9702011 A MX9702011 A MX 9702011A MX 9702011 A MX9702011 A MX 9702011A MX 9702011 A MX9702011 A MX 9702011A MX 9702011 A MX9702011 A MX 9702011A
- Authority
- MX
- Mexico
- Prior art keywords
- dahp
- overproduction
- cloned
- microorganisms
- methods
- Prior art date
Links
- PJWIPEXIFFQAQZ-PUFIMZNGSA-N 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonic acid Chemical compound OP(=O)(O)OC[C@@H](O)[C@@H](O)[C@H](O)CC(=O)C(O)=O PJWIPEXIFFQAQZ-PUFIMZNGSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 244000005700 microbiome Species 0.000 title 1
- 238000012261 overproduction Methods 0.000 title 1
- 101150043515 pps gene Proteins 0.000 title 1
- 230000037361 pathway Effects 0.000 abstract 2
- 108010062110 water dikinase pyruvate Proteins 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 230000002018 overexpression Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1294—Phosphotransferases with paired acceptors (2.7.9)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
- C12P13/227—Tryptophan
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/185—Escherichia
- C12R2001/19—Escherichia coli
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Se utilizan elementos genético que comprenden vectores de expansion y un gen que codifica para sintasa de fosfoenol piruvato, para mejorar la diversion de recursos de carbono en la trayectoria aromática comun y trayectoria que se ramifican de la misma. La sobreexpresion de sintasa de fosfoenol piruvato incrementa la produccion de DAHP a rendimientos casi teoricos.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30737194A | 1994-09-16 | 1994-09-16 | |
| US307,371 | 1994-09-16 | ||
| US307371 | 1994-09-16 | ||
| PCT/US1995/011701 WO1996008567A1 (en) | 1994-09-16 | 1995-09-15 | Microorganisms and methods for overproduction of dahp by cloned pps gene |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MXPA97002011A MXPA97002011A (es) | 1998-04-01 |
| MX9702011A true MX9702011A (es) | 1998-04-30 |
Family
ID=23189463
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9702011A MX9702011A (es) | 1994-09-16 | 1995-09-15 | Mocrioorganismos y metodos para la sobreproduccion de dahp mediante el gen pps clonado. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5906925A (es) |
| EP (1) | EP0782621B1 (es) |
| AT (1) | ATE319834T1 (es) |
| CA (1) | CA2199853C (es) |
| DE (1) | DE69534848T2 (es) |
| DK (1) | DK0782621T3 (es) |
| MX (1) | MX9702011A (es) |
| WO (1) | WO1996008567A1 (es) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5985617A (en) * | 1997-02-18 | 1999-11-16 | Liao; James C. | Microorganisms and methods for overproduction of DAHP by cloned PPS gene |
| DK0827542T3 (da) * | 1995-05-05 | 2008-08-18 | Genencor Int | Anvendelse af glucose-transport-mutanter til fremstilling af forbindelser fra den aromatiske pathway |
| JP4032441B2 (ja) | 1995-08-30 | 2008-01-16 | 味の素株式会社 | L−アミノ酸の製造方法 |
| US6210937B1 (en) * | 1997-04-22 | 2001-04-03 | Bechtel Bwxt Idaho, Llc | Development of genetically engineered bacteria for production of selected aromatic compounds |
| US6613552B1 (en) | 1999-01-29 | 2003-09-02 | Board Of Trustees Operating Michigan State University | Biocatalytic synthesis of shikimic acid |
| US6600077B1 (en) * | 1999-01-29 | 2003-07-29 | Board Of Trustees Operating Michigan State University | Biocatalytic synthesis of quinic acid and conversion to hydroquinone |
| AU5299000A (en) * | 1999-05-28 | 2000-12-18 | Tony Romeo | A global regulator used to enhance the synthesis of aromatic substances |
| US6830903B1 (en) * | 1999-07-23 | 2004-12-14 | Archer-Daniels-Midland Company | Methods for producing L-amino acids using a corynebacterium glutamicum with a disrupted pgi gene |
| EP2182072B1 (en) * | 1999-07-27 | 2012-12-26 | Food Industry Research and Development Institute | Method for producing isoprenoids |
| US6706516B1 (en) * | 1999-07-27 | 2004-03-16 | Food Industry Research And Development Institute | Engineering of metabolic control |
| SG146453A1 (en) * | 2002-04-23 | 2008-10-30 | Cargill Inc | Polypeptides and biosynthetic pathways |
| RU2268300C2 (ru) * | 2003-04-07 | 2006-01-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ОБЛАДАЮЩИХ ПОВЫШЕННОЙ ЭКСПРЕССИЕЙ ГЕНА pckA |
| US7790431B2 (en) * | 2003-09-24 | 2010-09-07 | Board Of Trustees Operating Michigan State University | Methods and materials for the production of shikimic acid |
| US8206955B2 (en) | 2003-10-21 | 2012-06-26 | Cargill, Incorporated | Production of monatin and monatin precursors |
| DE102005018835A1 (de) | 2005-04-22 | 2006-11-02 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung verbesserter Stämme der Familie Enterobacteriaceae |
| DE102005019040A1 (de) | 2005-04-23 | 2006-10-26 | Degussa Ag | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung verbesserter Stämme der Familie Enterobacteriaceae |
| JP2007117082A (ja) * | 2005-09-27 | 2007-05-17 | Ajinomoto Co Inc | L−アミノ酸生産菌及びl−アミノ酸の製造法 |
| RU2006129690A (ru) | 2006-08-16 | 2008-02-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНА ydiN, ГЕНА ydiB ИЛИ ИХ КОМБИНАЦИИ |
| JP2010017081A (ja) * | 2006-10-10 | 2010-01-28 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| JP2010017082A (ja) * | 2006-10-10 | 2010-01-28 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| JP2010041920A (ja) * | 2006-12-19 | 2010-02-25 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| EP2116595B1 (en) | 2007-01-22 | 2017-04-05 | Ajinomoto Co., Inc. | An l-amino acid-producing microorganism and a method for producing an l-amino acid |
| DE102007051024A1 (de) | 2007-03-05 | 2008-09-11 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| EP1975241A1 (de) | 2007-03-29 | 2008-10-01 | Evonik Degussa GmbH | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| DE102007044134A1 (de) | 2007-09-15 | 2009-03-19 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| DE102007052270A1 (de) | 2007-11-02 | 2009-05-07 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| EP2060636A1 (de) | 2007-11-14 | 2009-05-20 | Evonik Degussa GmbH | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| EP2098597A1 (de) | 2008-03-04 | 2009-09-09 | Evonik Degussa GmbH | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| DE102008002309A1 (de) | 2008-06-09 | 2009-12-10 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| DE102008040352A1 (de) | 2008-07-11 | 2010-01-14 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Tryptophan unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| DE102008044768A1 (de) | 2008-08-28 | 2010-03-04 | Evonik Degussa Gmbh | Verfahren zur Herstellung von organisch-chemischen Verbindungen unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
| WO2010027022A1 (ja) | 2008-09-05 | 2010-03-11 | 味の素株式会社 | L-アミノ酸生産菌及びl-アミノ酸の製造法 |
| PE20110369A1 (es) * | 2008-09-08 | 2011-06-24 | Ajinomoto Kk | Un microorganismo que produce l-aminoacido y un metodo para producir un l-aminoacido |
| JP2012029565A (ja) | 2008-11-27 | 2012-02-16 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| ES2648259T3 (es) | 2010-07-06 | 2017-12-29 | Yeda Research And Development Co. Ltd. | Plantas transgénicas que tienen alterada la actividad de la sintetasa DAHP |
| EP2778228B1 (en) | 2011-11-11 | 2017-05-17 | Ajinomoto Co., Inc. | Method for producing 2-ketoglutaric acid and derivatives thereof by using a bacterium from the genus pantoea or the genus corynebacterium |
| MY185322A (en) | 2013-05-13 | 2021-05-04 | Ajinomoto Kk | Method for producing l-amino acid |
| WO2015060314A1 (ja) | 2013-10-21 | 2015-04-30 | 味の素株式会社 | L-アミノ酸の製造法 |
| JP6519476B2 (ja) | 2013-10-23 | 2019-05-29 | 味の素株式会社 | 目的物質の製造法 |
| JP2017131111A (ja) | 2014-06-03 | 2017-08-03 | 味の素株式会社 | L−アミノ酸の製造法 |
| WO2018203947A2 (en) | 2017-02-06 | 2018-11-08 | Zymergen Inc. | Engineered biosynthetic pathways for production of tyramine by fermentation |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5168056A (en) * | 1991-02-08 | 1992-12-01 | Purdue Research Foundation | Enhanced production of common aromatic pathway compounds |
| US5272073A (en) * | 1992-06-30 | 1993-12-21 | Purdue Research Foundation | Biocatalytic synthesis of catechol from glucose |
-
1995
- 1995-09-15 DK DK95931835T patent/DK0782621T3/da active
- 1995-09-15 DE DE69534848T patent/DE69534848T2/de not_active Expired - Lifetime
- 1995-09-15 CA CA002199853A patent/CA2199853C/en not_active Expired - Fee Related
- 1995-09-15 MX MX9702011A patent/MX9702011A/es unknown
- 1995-09-15 EP EP95931835A patent/EP0782621B1/en not_active Expired - Lifetime
- 1995-09-15 WO PCT/US1995/011701 patent/WO1996008567A1/en not_active Ceased
- 1995-09-15 AT AT95931835T patent/ATE319834T1/de not_active IP Right Cessation
-
1997
- 1997-02-18 US US08/801,454 patent/US5906925A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69534848T2 (de) | 2006-11-23 |
| CA2199853A1 (en) | 1996-03-21 |
| US5906925A (en) | 1999-05-25 |
| ATE319834T1 (de) | 2006-03-15 |
| WO1996008567A1 (en) | 1996-03-21 |
| EP0782621A1 (en) | 1997-07-09 |
| DE69534848D1 (de) | 2006-05-04 |
| DK0782621T3 (da) | 2006-07-03 |
| WO1996008567B1 (en) | 2001-04-05 |
| EP0782621B1 (en) | 2006-03-08 |
| CA2199853C (en) | 2009-03-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX9702011A (es) | Mocrioorganismos y metodos para la sobreproduccion de dahp mediante el gen pps clonado. | |
| MY138770A (en) | Process for producing l-amino acid through fermentation | |
| Hahlbrock et al. | Light-induced changes of enzyme activities in parsley cell suspension cultures: effects of inhibitors of RNA and protein synthesis | |
| HU9904447D0 (en) | Process for fermentative production of d-pantotenic acid by increase pand-gene effect | |
| NZ514025A (en) | Compositions and methods for the modification of gene transcription | |
| BR9706059A (pt) | Dna recombinante autonomamente replicável em células de bactérias corineformes, bactéria corineforme abrigando uma aspartoquinase, processo para produzir l-lisa, dna, e vetor pvk7 | |
| BR9706058A (pt) | Dna recombinante replicável autonomamente em cédulas de bactérias corineformes, bactéria corineforme, e, processo para produzir l-lisina | |
| DE69637492D1 (de) | Anwendung von glukosetransportmutanten tur herstellung von verbindungen des aromatischen syntheseweges | |
| DE3382210D1 (de) | Hemmungsresistente 5-enolpyruvyl-3-phosphoshikimat-synthase, herstellung und verwendung. | |
| MY133278A (en) | Method of producing l-lysine by fermentation | |
| AU5722996A (en) | Production of 1,3-propanediol from glycerol by recombinant b acteria expressing recombinant diol dehydratase | |
| AU1878197A (en) | Agents and processes for the production of aquarial and garden pond water | |
| NO964754L (no) | DNA-kjede anvendelig i ökning av karotenoid utbytte | |
| WO2002030958A3 (de) | Casein-peptidfragmente mit wachstumsbeeinflussender aktivität auf zellkulturen | |
| EP0794256A3 (en) | Method for culturing microorganisms having methanol metabolic pathway | |
| GB9611981D0 (en) | Enhancement of gene expression | |
| EP0077196A3 (en) | Aromatic amino acid-producing microorganisms | |
| EP1672061A3 (en) | Nucleotide sequences encoding ACC synthase enzymes | |
| AU1682092A (en) | Production of plants resistant to attacks of sclerotinia sclerotiorum by introducing a gene coding for an oxalate oxidase | |
| EP1047710B1 (de) | Orotidin-5'-phosphatdecarboxylase-gen, genkonstrukt enthaltend dieses gen und seine verwendung | |
| MX215285B (en) | Process for preparing amides | |
| AU5000797A (en) | High level of expression of ingap | |
| FR2784688B1 (fr) | SEQUENCE D'ADNc DECRITE PAR SEQ ID N°1 TRANSCRIVANT UN ARNm CODANT POUR L'OXYDASE TERMINALE ASSOCIEE A LA BIOSYNTHESE DES CAROTENOIDES | |
| ES2125195A1 (es) | Procedimiento de inactivacion de genes que codifican para enzimas del catabolismo del fenilacetato, plasmidos que intervienen y cepas transformadas con los mismos. | |
| NZ505798A (en) | Process for the production of alanine by recombinant microorganisms |