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MX9701856A - Preparacion de liposomas multi-vesiculares para la liberacion controlada de agentes activos. - Google Patents

Preparacion de liposomas multi-vesiculares para la liberacion controlada de agentes activos.

Info

Publication number
MX9701856A
MX9701856A MX9701856A MX9701856A MX9701856A MX 9701856 A MX9701856 A MX 9701856A MX 9701856 A MX9701856 A MX 9701856A MX 9701856 A MX9701856 A MX 9701856A MX 9701856 A MX9701856 A MX 9701856A
Authority
MX
Mexico
Prior art keywords
liposomes
multivesicular liposomes
active substance
biologically active
preparation
Prior art date
Application number
MX9701856A
Other languages
English (en)
Inventor
Mantripragada B Sankaram
Sinil Kim
Original Assignee
Depotech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Depotech Corp filed Critical Depotech Corp
Publication of MX9701856A publication Critical patent/MX9701856A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/829—Liposomes, e.g. encapsulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

Se divulgan liposomas multi-vasiculares (MVLs) que contienen sustancias biologicamente activas, los liposomas multivesiculares teniendo distribucion de tamaños definida, tamaño promedio ajustable, tamaño y numero ajustable de cámaras internas, y una tasa de liberacion controlada y variable de la sustancia biologicamente activa. El proceso implica encapsular al menos una sustancia biologicamente activa y opcionalmente un separador osmotico en un primer componente acuoso encapsulado dentro de los liposomas. La tasa de liberacion de la sustancia activa hacia el ambiente circundante en el que se introducen los liposomas puede ser reducida incrementando la osmolaridad del primer componente acuoso o incrementada reduciendo la osmolaridad.
MX9701856A 1994-09-13 1997-03-12 Preparacion de liposomas multi-vesiculares para la liberacion controlada de agentes activos. MX9701856A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/305,158 US5993850A (en) 1994-09-13 1994-09-13 Preparation of multivesicular liposomes for controlled release of encapsulated biologically active substances

Publications (1)

Publication Number Publication Date
MX9701856A true MX9701856A (es) 1998-07-31

Family

ID=23179585

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9701856A MX9701856A (es) 1994-09-13 1997-03-12 Preparacion de liposomas multi-vesiculares para la liberacion controlada de agentes activos.

Country Status (14)

Country Link
US (1) US5993850A (es)
EP (1) EP0781123B1 (es)
JP (1) JP3026271B2 (es)
KR (1) KR100387561B1 (es)
CN (1) CN1096850C (es)
AU (1) AU697484B2 (es)
BR (1) BR9508913A (es)
CA (1) CA2199004C (es)
DE (1) DE69535297T2 (es)
FI (1) FI119621B (es)
MX (1) MX9701856A (es)
NO (1) NO323581B1 (es)
NZ (2) NZ292830A (es)
WO (1) WO1996008235A1 (es)

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Also Published As

Publication number Publication date
FI971037L (fi) 1997-05-12
NO971149D0 (no) 1997-03-12
EP0781123A1 (en) 1997-07-02
CN1166136A (zh) 1997-11-26
JP3026271B2 (ja) 2000-03-27
CA2199004C (en) 2008-02-19
BR9508913A (pt) 1997-12-30
NZ292830A (en) 1999-04-29
FI971037A0 (fi) 1997-03-12
FI119621B (fi) 2009-01-30
EP0781123B1 (en) 2006-11-15
AU697484B2 (en) 1998-10-08
DE69535297D1 (de) 2006-12-28
WO1996008235A1 (en) 1996-03-21
AU3511595A (en) 1996-03-29
NO323581B1 (no) 2007-06-11
DE69535297T2 (de) 2007-05-16
CA2199004A1 (en) 1996-03-21
NO971149L (no) 1997-05-13
CN1096850C (zh) 2002-12-25
JPH10502667A (ja) 1998-03-10
EP0781123A4 (en) 2000-12-20
NZ334561A (en) 2000-01-28
US5993850A (en) 1999-11-30
KR100387561B1 (ko) 2003-10-08

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