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MX379817B - Inhibidores de histona deacetilasa y composiciones y metodos para el uso de los mismos. - Google Patents

Inhibidores de histona deacetilasa y composiciones y metodos para el uso de los mismos.

Info

Publication number
MX379817B
MX379817B MX2017014299A MX2017014299A MX379817B MX 379817 B MX379817 B MX 379817B MX 2017014299 A MX2017014299 A MX 2017014299A MX 2017014299 A MX2017014299 A MX 2017014299A MX 379817 B MX379817 B MX 379817B
Authority
MX
Mexico
Prior art keywords
compositions
methods
histone deacetylase
deacetylase inhibitors
inhibitors
Prior art date
Application number
MX2017014299A
Other languages
English (en)
Other versions
MX2017014299A (es
Inventor
Alan F Haughan
de Poël Amanda Van
Andrew J Stott
Celia Dominguez
Christopher A Luckhurst
Elizabeth A Saville-Stones
Grant Wishart
Michael Wall
Michel C Maillard
Perla Breccia
Rebecca E Jarvis
Original Assignee
Chdi Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chdi Foundation Inc filed Critical Chdi Foundation Inc
Publication of MX2017014299A publication Critical patent/MX2017014299A/es
Publication of MX379817B publication Critical patent/MX379817B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

Se proporcionan ciertos inhibidores de la histona deacetilasa (HDAC) de Fórmula (I), sus composiciones y los métodos de su uso. (ver Fórmula).
MX2017014299A 2015-05-07 2016-05-06 Inhibidores de histona deacetilasa y composiciones y metodos para el uso de los mismos. MX379817B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562158379P 2015-05-07 2015-05-07
PCT/US2016/031329 WO2016179550A1 (en) 2015-05-07 2016-05-06 Histone deacetylase inhibitors and compositions and methods of use thereof

Publications (2)

Publication Number Publication Date
MX2017014299A MX2017014299A (es) 2018-08-09
MX379817B true MX379817B (es) 2025-03-11

Family

ID=57218066

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017014299A MX379817B (es) 2015-05-07 2016-05-06 Inhibidores de histona deacetilasa y composiciones y metodos para el uso de los mismos.

Country Status (12)

Country Link
US (2) US10047073B2 (es)
EP (1) EP3291809B1 (es)
JP (1) JP6782255B2 (es)
KR (1) KR20180002730A (es)
CN (1) CN107735087B (es)
AU (1) AU2016256917B2 (es)
BR (1) BR112017023710B1 (es)
CA (1) CA2984621C (es)
EA (1) EA035592B1 (es)
IL (1) IL255449B2 (es)
MX (1) MX379817B (es)
WO (1) WO2016179550A1 (es)

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JP6782255B2 (ja) * 2015-05-07 2020-11-11 シーエイチディーアイ ファウンデーション，インコーポレーテッド ヒストンデアセチラーゼ阻害薬及び組成物並びにそれらの使用の方法
BR112018074559A2 (pt) * 2016-06-09 2019-03-12 Basf Se compostos, composição agroquímica, uso de compostos e método para combater fungos nocivos fitopatogênicos
WO2018015447A1 (en) * 2016-07-22 2018-01-25 Syngenta Participations Ag Microbiocidal oxadiazole derivatives
US10357493B2 (en) 2017-03-10 2019-07-23 Selenity Therapeutics (Bermuda), Ltd. Metalloenzyme inhibitor compounds
WO2019219464A1 (en) 2018-05-15 2019-11-21 Basf Se Substituted trifluoromethyloxadiazoles for combating phytopathogenic fungi
KR102052844B1 (ko) 2019-01-31 2019-12-05 주식회사 아이스크림에듀 학습 분석 방법 및 시스템
KR102009034B1 (ko) 2019-01-31 2019-08-08 주식회사 아이스크림에듀 학습 분석을 기초로 정보를 제공하는 방법 및 시스템
JP2022543106A (ja) 2019-07-30 2022-10-07 エイコニゾ セラピューティクス，インコーポレーテッド Ｈｄａｃ６インヒビターおよびそれらの使用
KR102232343B1 (ko) 2019-12-11 2021-03-26 주식회사 아이스크림에듀 인공지능 기반 맞춤형 학습 방법 및 시스템
KR102191672B1 (ko) 2019-12-20 2020-12-16 주식회사 아이스크림에듀 학습 분석 및 인공지능 기반 맞춤형 학습 방법 및 시스템
KR102197752B1 (ko) 2019-12-20 2021-01-04 주식회사 아이스크림에듀 맞춤형 자동 문항 생성을 통한 인공지능 기반 학습 방법 및 시스템
KR102191670B1 (ko) 2019-12-20 2020-12-16 주식회사 아이스크림에듀 문제은행 및 지식맵 기반 맞춤형 학습 방법 및 시스템
KR102191671B1 (ko) 2019-12-20 2020-12-16 주식회사 아이스크림에듀 소셜 러닝 및 e포트폴리오 기반 맞춤형 학습 방법 및 시스템
KR102258235B1 (ko) 2020-02-27 2021-05-31 주식회사 아이스크림에듀 실감 콘텐츠가 적용된 인공지능 기반의 맞춤형 학습 방법 및 시스템
KR102232344B1 (ko) 2020-02-27 2021-03-26 주식회사 아이스크림에듀 빅데이터 및 인공지능 기반의 맞춤형 학습 방법 및 시스템
KR102258234B1 (ko) 2020-02-27 2021-05-31 주식회사 아이스크림에듀 인공지능 가정교사 인터페이스가 적용된 맞춤형 학습 방법 및 시스템
CN111190006A (zh) * 2020-03-09 2020-05-22 上海市东方医院（同济大学附属东方医院） 组蛋白去乙酰化酶6在制备用于评估维持性腹膜透析患者腹膜功能的标志物中的用途
KR102222533B1 (ko) 2020-06-25 2021-03-05 주식회사 아이스크림미디어 고정형 웹 콘텐츠를 반응형 콘텐츠로 자동 변환하는 시스템 및 그 제어방법
US20230286970A1 (en) * 2020-08-07 2023-09-14 Italfarmaco S.P.A. Novel oxadiazole-based selective hdac6 inhibitors
KR102248960B1 (ko) 2020-08-19 2021-05-07 주식회사 아이스크림에듀 인공지능 학습 플랫폼을 이용한 비즈니스 방법 및 시스템
CN117430513A (zh) * 2023-10-27 2024-01-23 中昊(大连)化工研究设计院有限公司 环丙基胺的合成新方法

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Also Published As

Publication number Publication date
US20190185463A1 (en) 2019-06-20
EP3291809A4 (en) 2018-10-03
WO2016179550A1 (en) 2016-11-10
CN107735087B (zh) 2021-09-03
JP2018515492A (ja) 2018-06-14
BR112017023710A2 (pt) 2018-07-31
HK1252489A1 (zh) 2019-05-24
CN107735087A (zh) 2018-02-23
JP6782255B2 (ja) 2020-11-11
US20160333001A1 (en) 2016-11-17
EA201792255A1 (ru) 2018-06-29
KR20180002730A (ko) 2018-01-08
BR112017023710B1 (pt) 2023-03-07
IL255449B2 (en) 2023-07-01
EP3291809A1 (en) 2018-03-14
IL255449A0 (en) 2017-12-31
AU2016256917B2 (en) 2021-08-26
EA035592B1 (ru) 2020-07-13
EP3291809B1 (en) 2021-08-25
IL255449B1 (en) 2023-03-01
MX2017014299A (es) 2018-08-09
CA2984621C (en) 2023-09-26
US10047073B2 (en) 2018-08-14
AU2016256917A1 (en) 2017-11-23
CA2984621A1 (en) 2016-11-10

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