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MX2023003058A - Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía. - Google Patents

Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía.

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Publication number
MX2023003058A
MX2023003058A MX2023003058A MX2023003058A MX2023003058A MX 2023003058 A MX2023003058 A MX 2023003058A MX 2023003058 A MX2023003058 A MX 2023003058A MX 2023003058 A MX2023003058 A MX 2023003058A MX 2023003058 A MX2023003058 A MX 2023003058A
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Mexico
Prior art keywords
energy
genetically engineered
engineered bacterium
fermentation pathway
buk
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MX2023003058A
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English (en)
Inventor
James Bruce Yarnton Haycock Behrendorff
Alexander Paul Mueller
Michael Kopke
Ryan Edward Hill
Rasmus Overgaard Jensen
Darmawi Juminaga
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Lanzatech Nz Inc
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Application filed by Lanzatech Nz Inc filed Critical Lanzatech Nz Inc
Publication of MX2023003058A publication Critical patent/MX2023003058A/es

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Abstract

La presente invención se refiere a una bacteria diseñada por ingeniería genética que tiene una enzima que convierte 3-hidroxiisovaleril-CoA en 3-hidroxiisovalerato y una enzima que convierte 3-hidroxiisovalerato en isobutilen. Por lo general, la bacteria es capaz de producir isobutilen a partir de un sustrato gaseoso que contiene CO, CO2 y/o H2, como el syngas o un gas de desperdicio industrial.
MX2023003058A 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía. MX2023003058A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562240850P 2015-10-13 2015-10-13
PCT/US2016/056926 WO2017066498A1 (en) 2015-10-13 2016-10-13 Genetically engineered bacterium comprising energy-generating fermentation pathway

Publications (1)

Publication Number Publication Date
MX2023003058A true MX2023003058A (es) 2023-04-05

Family

ID=58499646

Family Applications (4)

Application Number Title Priority Date Filing Date
MX2023003058A MX2023003058A (es) 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía.
MX2018004642A MX391661B (es) 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía
MX2022003568A MX2022003568A (es) 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía.
MX2021003330A MX2021003330A (es) 2015-10-13 2018-04-13 Bacteria dise?ada por ingenieria genetica que comprende una trayectoria de fermentacion que genera energia.

Family Applications After (3)

Application Number Title Priority Date Filing Date
MX2018004642A MX391661B (es) 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía
MX2022003568A MX2022003568A (es) 2015-10-13 2016-10-13 Bacteria diseñada por ingeniería genética que comprende una trayectoria de fermentación que genera energía.
MX2021003330A MX2021003330A (es) 2015-10-13 2018-04-13 Bacteria dise?ada por ingenieria genetica que comprende una trayectoria de fermentacion que genera energia.

Country Status (12)

Country Link
US (3) US9738875B2 (es)
EP (2) EP3362567A4 (es)
JP (2) JP6905518B2 (es)
KR (2) KR20210037002A (es)
CN (2) CN108884467A (es)
AU (2) AU2016339989B2 (es)
CA (6) CA3051234C (es)
EA (2) EA202190729A1 (es)
MX (4) MX2023003058A (es)
MY (5) MY200202A (es)
WO (1) WO2017066498A1 (es)
ZA (5) ZA201802346B (es)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130323820A1 (en) 2012-06-01 2013-12-05 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
MA40644A (fr) * 2014-09-17 2016-03-24 Global Bioenergies Procédés pour produire de l'acide 3-hydroxy-3-méthylbutyrique
US11291693B2 (en) 2015-06-25 2022-04-05 Synlogic Operating Company, Inc. Bacteria engineered to treat metabolic diseases
CA3051234C (en) * 2015-10-13 2020-09-15 Lanzatech New Zealand Limited Genetically engineered bacterium comprising energy-generating fermentation pathway
GB201603915D0 (en) * 2016-03-07 2016-04-20 Chain Biotechnology Ltd Method and microbes for the production of chiral compounds
WO2017200884A1 (en) 2016-05-14 2017-11-23 Lanzatech, Inc. Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods
US11539066B2 (en) 2016-11-22 2022-12-27 The Penn State Research Foundation Devices and methods for generating electrical current from methane
CN107177609B (zh) * 2017-05-15 2020-12-11 大连理工大学 一种fruB基因过表达的重组梭菌、其构建方法及应用
CN107083406B (zh) * 2017-05-27 2021-02-02 浙江华睿生物技术有限公司 (r)-3-羟基丁酸的生产方法
US11634733B2 (en) * 2017-06-30 2023-04-25 Inv Nylon Chemicals Americas, Llc Methods, materials, synthetic hosts and reagents for the biosynthesis of hydrocarbons and derivatives thereof
SG11202001716XA (en) 2017-09-08 2020-03-30 Lanzatech Inc Processes and systems for metabolite production using hydrogen rich c1-containing substrates
KR20200050470A (ko) * 2017-09-28 2020-05-11 란자테크, 인크. 우드-륭달 미생물에서 유전자 녹아웃
US11505809B2 (en) 2017-09-28 2022-11-22 Inv Nylon Chemicals Americas Llc Organisms and biosynthetic processes for hydrocarbon synthesis
CN111386339B (zh) 2017-11-30 2024-05-10 东丽株式会社 用于生产3-羟基己二酸、α-氢化己二烯二酸及/或己二酸的基因修饰微生物以及该化学产品的制造方法
WO2019126400A1 (en) 2017-12-19 2019-06-27 Lanzatech, Inc. Microorganisms and methods for the biological production of ethylene glycol
EP3743520A4 (en) * 2018-01-23 2021-11-10 Lanzatech, Inc. TWO-STAGE FERMENTATION PROCESS FOR MANUFACTURING A PRODUCT
US11661613B2 (en) 2018-02-01 2023-05-30 Inv Nylon Chemicals Americas, Llc Methods and materials for the biosynthesis of hydroxy fatty acid anions and/or derivatives thereof and/or compounds related thereto
EP3752276A4 (en) 2018-02-12 2021-11-17 Lanzatech, Inc. METHODS FOR IMPROVING CARBON CONVERSION EFFICIENCY
EP3781668B1 (en) 2018-04-20 2023-10-04 Lanzatech, Inc. Fermentation process for producing ethanol
CN109251940B (zh) * 2018-10-30 2020-10-16 浙江华睿生物技术有限公司 一种产β-羟基-β-甲基丁酸工程菌的构建方法
KR102549843B1 (ko) 2018-11-19 2023-06-29 란자테크, 인크. 발효와 가스화의 통합
EP3921433A4 (en) 2019-02-08 2022-11-23 Lanzatech, Inc. PROCESS FOR RECOVERING NEAR BOILING POINT PRODUCTS
BR112021018090A2 (pt) 2019-03-20 2021-11-23 Global Bioenergies Organismo ou micro-organismo recombinante, uso do organismo ou micro-organismo recombinante e método para a produção de isobuteno
FR3096373B1 (fr) * 2019-05-24 2024-09-13 Ifp Energies Now Outil genetique optimisé pour modifier les bacteries
SG11202111976TA (en) 2019-07-11 2021-11-29 Lanzatech Inc Methods for optimizing gas utilization
WO2021011763A1 (en) * 2019-07-16 2021-01-21 San Diego State University (SDSU) Foundation, dba San Diego State University Research Foundation Products of manufacture and methods for methane capturing using biofiltration
CN112280723B (zh) * 2019-07-23 2022-08-19 清华大学 联产1,3-丙二醇和1,3-丁二醇的重组菌及其应用
CN112280722B (zh) * 2019-07-23 2022-03-08 清华大学 用于生产光学纯1,3-丁二醇的重组菌及其应用
JP7376041B2 (ja) * 2019-09-11 2023-11-08 公益財団法人地球環境産業技術研究機構 形質転換体及びそれを用いる1,3-ブタンジオールの製造方法
CN111089914A (zh) * 2019-11-07 2020-05-01 河北首朗新能源科技有限公司 微生物发酵生产乙醇中代谢物的高效液相检测方法
CN114846050B (zh) * 2019-12-23 2025-01-14 希欧生物清洁有限公司 新型生物塑料
JP7475598B2 (ja) * 2020-03-04 2024-04-30 大阪瓦斯株式会社 1,3-ブタンジオールの製造方法
US11932818B2 (en) 2020-03-16 2024-03-19 Lanzatech, Inc. Tail gas of gas fermentation to dry gasification feedstock
CN113840909A (zh) 2020-03-18 2021-12-24 朗泽科技有限公司 从气态底物发酵生产2-苯乙醇
CN111220762A (zh) * 2020-03-24 2020-06-02 河北首朗新能源科技有限公司 一种乙醇梭菌蛋白中有机物的含量的检测方法及应用
BR112022021838A2 (pt) * 2020-04-29 2022-12-13 Lanzatech Inc Microrganismo, método para produzir ss-cetoadipato, e, método de produção de um polímero
CA3224707A1 (en) * 2020-06-06 2021-12-09 Lanzatech, Inc. Microorganism with knock-in at acetolactate decarboxylase gene locus
KR20230042416A (ko) * 2020-09-25 2023-03-28 란자테크, 인크. 재조합 미생물 및 이의 용도
KR102443037B1 (ko) 2020-10-23 2022-09-14 한국과학기술연구원 에탄올을 포함하는 합성 가스로부터 2,3-부탄디올 제조용 배지 조성물 및 이를 이용한 2,3-부탄디올 생산 방법
CN116348603B (zh) 2021-02-08 2024-07-02 朗泽科技有限公司 重组微生物及其用途
JP7645685B2 (ja) * 2021-03-31 2025-03-14 大阪瓦斯株式会社 2-ヒドロキシイソ酪酸産生能を有する微生物及び2-ヒドロキシイソ酪酸の製造方法
JP2024513395A (ja) 2021-04-09 2024-03-25 ランザテク,インコーポレイテッド 供給原料を提供するためのプロセス及び装置
CN115369048B (zh) * 2021-05-17 2023-10-20 华东理工大学 一种产玉米黄质的解脂耶氏酵母基因工程菌及其构建方法和应用
US12241105B2 (en) 2021-07-20 2025-03-04 Lanzatech, Inc. Recombinant microorganisms and uses therefor
TW202307202A (zh) 2021-08-06 2023-02-16 美商朗澤科技有限公司 用於改良乙二醇之生物產生的微生物及方法
US12091648B2 (en) 2021-11-03 2024-09-17 Lanzatech, Inc. System and method for generating bubbles in a vessel
CN116376856B (zh) * 2022-04-06 2023-11-03 深圳蓝晶生物科技有限公司 表达乙酰乙酰辅酶a还原酶变体的工程化微生物及提高pha产量的方法
US11913056B2 (en) 2022-04-06 2024-02-27 Shenzhen Bluepha Biosciences Co., Ltd. Engineered microorganisms expressing acetoacetyl-CoA reductase variants and method for improving the yield of PHA
US12280331B2 (en) 2022-04-29 2025-04-22 Lanzatech, Inc. Low residence time gas separator
US12077800B2 (en) 2022-06-16 2024-09-03 Lanzatech, Inc. Liquid distributor system and process of liquid distribution
AU2023286621A1 (en) 2022-06-21 2025-01-09 Lanzatech, Inc. Microorganisms and methods for the continuous co-production of tandem repeat proteins and chemical products from c1-substrates
JP2025525381A (ja) 2022-06-21 2025-08-05 ランザテク,インコーポレイテッド C1基質からの高価値の特殊タンパク質及び化学産物の連続共産生のための微生物及び方法
US12129503B2 (en) 2022-08-10 2024-10-29 Lanzatech, Inc. Carbon sequestration in soils with production of chemical products
US12359224B2 (en) 2023-06-05 2025-07-15 Lanzatech, Inc. Integrated gas fermentation and carbon black processes
US12281344B2 (en) 2023-06-05 2025-04-22 Lanzatech, Inc. Integrated gas fermentation

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5593886A (en) 1992-10-30 1997-01-14 Gaddy; James L. Clostridium stain which produces acetic acid from waste gases
UA72220C2 (uk) 1998-09-08 2005-02-15 Байоенджініерінг Рісорсиз, Інк. Незмішувана з водою суміш розчинник/співрозчинник для екстрагування оцтової кислоти, спосіб одержання оцтової кислоти (варіанти), спосіб анаеробного мікробного бродіння для одержання оцтової кислоти (варіанти), модифікований розчинник та спосіб його одержання
CN1217001C (zh) * 2002-01-04 2005-08-31 清华大学 一种生产d-(-)-3-羟基丁酸的方法
CN101432434B (zh) * 2005-09-29 2015-03-11 布特马斯先进生物燃料公司 4碳醇的发酵生产
NZ546496A (en) 2006-04-07 2008-09-26 Lanzatech New Zealand Ltd Gas treatment process
US7704723B2 (en) 2006-08-31 2010-04-27 The Board Of Regents For Oklahoma State University Isolation and characterization of novel clostridial species
NZ553984A (en) 2007-03-19 2009-07-31 Lanzatech New Zealand Ltd Alcohol production process
KR101114918B1 (ko) * 2007-08-09 2012-02-15 주식회사 엘지화학 재조합 미생물을 이용한 광학활성(s)-3-하이드록시부탄산 및(s)-3-하이드록시부티레이트 에스테르의 제조방법
KR101042242B1 (ko) * 2007-09-07 2011-06-17 한국과학기술원 1,4-부탄디올 생성능을 가지는 변이체 및 이를 이용한1,4-부탄디올의 제조방법
EP2217696B1 (en) 2007-11-13 2015-09-16 Lanzatech New Zealand Limited Novel bacteria and methods of use thereof
CN106119112B (zh) * 2008-03-27 2021-07-13 基因组股份公司 用于产生己二酸和其他化合物的微生物
BRPI0915017B1 (pt) 2008-06-09 2018-12-26 Lanzatech New Zealand Ltd método para produzir 2,3-butanodiol pela fermentação microbiana de um substrato gasoso compreendendo co
PL2304040T3 (pl) 2008-07-04 2018-01-31 Scientist Of Fortune Sa Wytwarzanie alkenów za pomocą dekarboksylacji enzymatycznej kwasów 3-hydroksyalkanowych
WO2010022763A1 (en) * 2008-08-25 2010-03-04 Metabolic Explorer Method for the preparation of 2-hydroxy-isobutyrate
US8895288B2 (en) * 2008-12-30 2014-11-25 Danisco Us Inc. Methods of producing isoprene and a co-product
WO2011031897A1 (en) * 2009-09-09 2011-03-17 Genomatica, Inc. Microorganisms and methods for the co-production of isopropanol with primary alcohols, diols and acids
EP2295593A1 (en) 2009-09-15 2011-03-16 Philippe Marliere Method for the enymatic production of 3-hydroxy-3-methylbutyric acid from acetone and acetyl-CoA
SG181607A1 (en) * 2009-12-10 2012-07-30 Genomatica Inc Methods and organisms for converting synthesis gas or other gaseous carbon sources and methanol to 1,3-butanediol
EP2336341A1 (en) 2009-12-21 2011-06-22 Philippe Marliere Method for producing an alkene comprising the step of converting an alcohol by an enzymatic dehydration step
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
CN102791869B (zh) 2010-03-10 2015-08-19 朗泽科技新西兰有限公司 通过发酵的酸产生
EP2606138A2 (en) 2010-08-19 2013-06-26 Lanzatech New Zealand Limited A process for producing chemicals using microbial fermentation of substrates comprising carbon monoxide
WO2012026833A1 (en) 2010-08-26 2012-03-01 Lanzatech New Zealand Limited Process for producing ethanol and ethylene via fermentation
US20110236941A1 (en) * 2010-10-22 2011-09-29 Lanzatech New Zealand Limited Recombinant microorganism and methods of production thereof
US8271519B2 (en) 2010-11-01 2012-09-18 Sas Institute Inc. Systems and methods for fast remote data access from a spreadsheet
US9365868B2 (en) * 2011-02-25 2016-06-14 Lanzatech New Zealand Limited Fermentation process for producing isopropanol using a recombinant microorganism
DK2678432T3 (en) * 2011-02-25 2018-11-26 Lanzatech New Zealand Ltd RECOMBINANT MICROORGANISMS AND APPLICATIONS THEREOF
AU2012305021B2 (en) 2011-09-08 2016-06-09 Lanzatech Nz, Inc. A fermentation process
EP2710117B1 (en) 2012-01-31 2016-04-27 Lanzatech New Zealand Limited Recombinant microorganisms and methods of use thereof
CN104508136A (zh) 2012-05-30 2015-04-08 新西兰郎泽科技公司 重组微生物及其用途
US20130323820A1 (en) 2012-06-01 2013-12-05 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
CN113186144A (zh) 2012-06-08 2021-07-30 朗泽科技新西兰有限公司 重组微生物和其用途
US9347076B2 (en) 2012-06-21 2016-05-24 Lanzatech New Zealand Limited Recombinant microorganisms that make biodiesel
JP6302471B2 (ja) 2012-08-28 2018-03-28 ランザテク・ニュージーランド・リミテッド 組換え微生物およびその使用
US8787096B1 (en) 2013-01-16 2014-07-22 Qualcomm Incorporated N-well switching circuit
EP2813575A1 (de) * 2013-06-14 2014-12-17 Evonik Industries AG Verfahren zur Herstellung von organischen Verbindungen aus Knallgas und CO2 über Acetoacetyl-CoA als Zwischenprodukt
WO2015084633A1 (en) * 2013-12-03 2015-06-11 Genomatica, Inc. Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis
JP2016538869A (ja) 2013-12-03 2016-12-15 ランザテク・ニュージーランド・リミテッド ケトンの生成のための微生物及び方法
WO2015101493A1 (en) * 2013-12-31 2015-07-09 Global Bioenergies 3-hydroxyisovalerate (hiv) synthase variants
EP3189130A1 (en) 2014-09-03 2017-07-12 Global Bioenergies Recombinant microorganism producing alkenes from acetyl-coa
CA3051234C (en) * 2015-10-13 2020-09-15 Lanzatech New Zealand Limited Genetically engineered bacterium comprising energy-generating fermentation pathway

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