MX2023002672A - Metodo para eliminar agentes antiespumantes de un caldo de fermentacion. - Google Patents
Metodo para eliminar agentes antiespumantes de un caldo de fermentacion.Info
- Publication number
- MX2023002672A MX2023002672A MX2023002672A MX2023002672A MX2023002672A MX 2023002672 A MX2023002672 A MX 2023002672A MX 2023002672 A MX2023002672 A MX 2023002672A MX 2023002672 A MX2023002672 A MX 2023002672A MX 2023002672 A MX2023002672 A MX 2023002672A
- Authority
- MX
- Mexico
- Prior art keywords
- fermentation broth
- antifoaming agent
- interest
- molecule
- antifoaming agents
- Prior art date
Links
- 239000002518 antifoaming agent Substances 0.000 title abstract 7
- 238000000855 fermentation Methods 0.000 title abstract 6
- 230000004151 fermentation Effects 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 5
- 238000001914 filtration Methods 0.000 abstract 1
- 229920001515 polyalkylene glycol Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21062—Subtilisin (3.4.21.62)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
La presente invención se refiere a un método para separar una molécula de interés de un agente antiespumante en un caldo de fermentación que comprende dicha molécula de interés y dicho agente antiespumante. El método comprende las etapas de filtrar el caldo de fermentación a una temperatura en el rango de 1°C a 15°C por encima del punto de turbidez del agente antiespumante, y de este modo obtener una primera fracción del caldo de fermentación que comprende la molécula de interés y una segunda fracción del caldo de fermentación que comprende el agente antiespumante, en donde el agente antiespumante es un agente antiespumante a base de polialquilenglicol. La invención además se refiere a un proceso para purificar una molécula de interés a partir de un caldo de fermentación que comprende dicho método.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20194676 | 2020-09-04 | ||
| PCT/EP2021/074332 WO2022049228A1 (en) | 2020-09-04 | 2021-09-03 | Method for removing antifoaming agents from a fermentation broth |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2023002672A true MX2023002672A (es) | 2023-03-28 |
Family
ID=72422064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023002672A MX2023002672A (es) | 2020-09-04 | 2021-09-03 | Metodo para eliminar agentes antiespumantes de un caldo de fermentacion. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230323329A1 (es) |
| EP (1) | EP4208561A1 (es) |
| KR (1) | KR20230061387A (es) |
| CN (1) | CN116096854A (es) |
| BR (1) | BR112023003778A2 (es) |
| CA (1) | CA3191023A1 (es) |
| MX (1) | MX2023002672A (es) |
| WO (1) | WO2022049228A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025093743A1 (en) * | 2023-11-02 | 2025-05-08 | Chr. Hansen A/S | Methods for improving one or more process parameters of a fermentation process |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4931397A (en) | 1985-09-24 | 1990-06-05 | Miles Inc. | Method for removing antifoaming agents during processing of microbial fermentations |
| CA2156829C (en) | 1993-02-26 | 1999-06-08 | Paul Amaat R. G. France | High active enzyme granulates |
| DE19619221A1 (de) | 1996-05-13 | 1997-11-20 | Solvay Enzymes Gmbh & Co Kg | Enzymgranulat für Wasch- und Reinigungsanwendungen |
| PT970236E (pt) | 1997-02-20 | 2006-08-31 | Dsm Ip Assets Bv | Producao fermentativa de compostos valiosos a escala industrial utilizando meios quimicamente definidos |
| EP1520011A2 (en) | 2002-07-01 | 2005-04-06 | Novozymes A/S | Sterilisation of a fermentation medium comprising hydrolysed n-source |
| ES2436498T3 (es) * | 2007-10-18 | 2014-01-02 | Unilever N.V. | Método para producir un agente espumante |
| DK2346987T3 (en) | 2008-10-16 | 2016-04-25 | Unilever Nv | Hydrophobin solution with anti-foaming agent |
-
2021
- 2021-09-03 CA CA3191023A patent/CA3191023A1/en active Pending
- 2021-09-03 EP EP21770250.5A patent/EP4208561A1/en active Pending
- 2021-09-03 BR BR112023003778A patent/BR112023003778A2/pt not_active Application Discontinuation
- 2021-09-03 WO PCT/EP2021/074332 patent/WO2022049228A1/en not_active Ceased
- 2021-09-03 KR KR1020237007483A patent/KR20230061387A/ko not_active Withdrawn
- 2021-09-03 US US18/023,130 patent/US20230323329A1/en active Pending
- 2021-09-03 CN CN202180054439.0A patent/CN116096854A/zh active Pending
- 2021-09-03 MX MX2023002672A patent/MX2023002672A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA3191023A1 (en) | 2022-03-10 |
| WO2022049228A1 (en) | 2022-03-10 |
| EP4208561A1 (en) | 2023-07-12 |
| US20230323329A1 (en) | 2023-10-12 |
| CN116096854A (zh) | 2023-05-09 |
| BR112023003778A2 (pt) | 2023-03-28 |
| KR20230061387A (ko) | 2023-05-08 |
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