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MX2021008064A - Antagonista de union al eje pd-1 e inhibidores de tigit para usarse en el tratamiento de cancer. - Google Patents

Antagonista de union al eje pd-1 e inhibidores de tigit para usarse en el tratamiento de cancer.

Info

Publication number
MX2021008064A
MX2021008064A MX2021008064A MX2021008064A MX2021008064A MX 2021008064 A MX2021008064 A MX 2021008064A MX 2021008064 A MX2021008064 A MX 2021008064A MX 2021008064 A MX2021008064 A MX 2021008064A MX 2021008064 A MX2021008064 A MX 2021008064A
Authority
MX
Mexico
Prior art keywords
methods
axis binding
treating cancer
binding antagonists
tigit inhibitors
Prior art date
Application number
MX2021008064A
Other languages
English (en)
Inventor
Kristin Bowles
Laetitia Comps-Agrar
Bryan Irving
Robert J Johnston
Xin Yu
Jane Grogan
Jason Hackney
Dan Eaton
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51300845&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2021008064(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2021008064A publication Critical patent/MX2021008064A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
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    • C07K16/3023—Lung
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/3046—Stomach, Intestines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • A01K2227/10—Mammal
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

La presente invención describe un tratamiento de combinación que comprende un antagonista de unión al eje PD-1 y un agente que disminuye o inhibe la expresión y/o la actividad de TIGIT y métodos para su uso, incluyendo métodos para tratar condiciones en donde se desea una inmunogenicidad mejorada tal como el incremento de la inmunogenicidad del tumor para el tratamiento de cáncer o infección crónica.
MX2021008064A 2013-07-16 2016-01-14 Antagonista de union al eje pd-1 e inhibidores de tigit para usarse en el tratamiento de cancer. MX2021008064A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361846941P 2013-07-16 2013-07-16
US201361865582P 2013-08-13 2013-08-13
US201461950754P 2014-03-10 2014-03-10
US201461985884P 2014-04-29 2014-04-29
US201461992109P 2014-05-12 2014-05-12

Publications (1)

Publication Number Publication Date
MX2021008064A true MX2021008064A (es) 2021-08-05

Family

ID=51300845

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016000510A MX384142B (es) 2013-07-16 2014-07-16 Antagonista de unión al eje pd-1 e inhibidores de tigit para usarse en el tratamiento de cáncer.
MX2021008064A MX2021008064A (es) 2013-07-16 2016-01-14 Antagonista de union al eje pd-1 e inhibidores de tigit para usarse en el tratamiento de cancer.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2016000510A MX384142B (es) 2013-07-16 2014-07-16 Antagonista de unión al eje pd-1 e inhibidores de tigit para usarse en el tratamiento de cáncer.

Country Status (26)

Country Link
US (7) US9873740B2 (es)
EP (2) EP3021869B1 (es)
JP (5) JP6636920B2 (es)
KR (4) KR20160030936A (es)
CN (2) CN121197418A (es)
AU (4) AU2014290069B2 (es)
BR (1) BR112016000853A2 (es)
CA (1) CA2916681A1 (es)
DK (1) DK3021869T3 (es)
ES (1) ES2819209T3 (es)
HK (1) HK1217283A1 (es)
HR (1) HRP20201404T1 (es)
HU (1) HUE050496T2 (es)
IL (3) IL320652A (es)
LT (1) LT3021869T (es)
MX (2) MX384142B (es)
MY (1) MY183503A (es)
PL (1) PL3021869T3 (es)
PT (1) PT3021869T (es)
RS (1) RS60826B1 (es)
RU (1) RU2702108C2 (es)
SG (1) SG11201600310QA (es)
SI (1) SI3021869T1 (es)
TW (2) TWI888366B (es)
WO (1) WO2015009856A2 (es)
ZA (2) ZA201800079B (es)

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EP2277532A1 (en) 2002-09-11 2011-01-26 Genentech, Inc. Novel composition and methods for the treatment of immune related diseases
JP2008544746A (ja) 2005-05-12 2008-12-11 ザイモジェネティクス， インコーポレイテッド 免疫応答を調節するための組成物および方法
HUE036780T2 (hu) 2008-04-09 2018-07-30 Genentech Inc Új kompozíciók és eljárások immunológiai vonatkozású betegségek kezelésére
DK3702371T5 (da) 2009-03-25 2024-08-26 Genentech Inc Anti-FGFR3-antistoffer og fremgangsmåder ved anvendelse af disse
CA2860170C (en) 2010-12-22 2022-06-14 The Board Of Trustees Of The Leland Stanford Junior University Superagonists and antagonists of interleukin-2
EP2758073B1 (en) 2011-09-23 2018-10-31 OncoMed Pharmaceuticals, Inc. Vegf/dll4 binding agents and uses thereof
MX2015007051A (es) 2012-12-07 2016-01-12 Chemocentryx Inc Diazol lactamas.
KR20160030936A (ko) 2013-07-16 2016-03-21 제넨테크, 인크. Pd-1 축 결합 길항제 및 tigit 억제제를 사용한 암을 치료하는 방법
CN105722860A (zh) 2013-09-24 2016-06-29 梅迪塞纳医疗股份有限公司 白介素-2融合蛋白及其应用
WO2015048312A1 (en) 2013-09-26 2015-04-02 Costim Pharmaceuticals Inc. Methods for treating hematologic cancers
TWI681969B (zh) 2014-01-23 2020-01-11 美商再生元醫藥公司 針對ｐｄ-１的人類抗體
TWI680138B (zh) 2014-01-23 2019-12-21 美商再生元醫藥公司 抗ｐｄ-ｌ１之人類抗體
JOP20200094A1 (ar) 2014-01-24 2017-06-16 Dana Farber Cancer Inst Inc جزيئات جسم مضاد لـ pd-1 واستخداماتها
JOP20200096A1 (ar) 2014-01-31 2017-06-16 Children’S Medical Center Corp جزيئات جسم مضاد لـ tim-3 واستخداماتها
US10519237B2 (en) 2014-03-12 2019-12-31 Yeda Research And Development Co. Ltd Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
BR112016020919A2 (pt) 2014-03-12 2018-01-23 Yeda Res & Dev redução dos níveis ou da atividade sistêmica de células t regulatórias para o tratamento de doença e lesão do snc
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