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MX2020004344A - Objetivos genéticos para el direccionamiento de fijación de nitrógeno para mejorar los rasgos de las plantas. - Google Patents

Objetivos genéticos para el direccionamiento de fijación de nitrógeno para mejorar los rasgos de las plantas.

Info

Publication number
MX2020004344A
MX2020004344A MX2020004344A MX2020004344A MX2020004344A MX 2020004344 A MX2020004344 A MX 2020004344A MX 2020004344 A MX2020004344 A MX 2020004344A MX 2020004344 A MX2020004344 A MX 2020004344A MX 2020004344 A MX2020004344 A MX 2020004344A
Authority
MX
Mexico
Prior art keywords
nitrogen fixation
gene targets
improving plant
plant traits
deletion
Prior art date
Application number
MX2020004344A
Other languages
English (en)
Inventor
Alvin Tamsir
Sarah Bloch
Neal Shah
Original Assignee
Pivot Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pivot Bio Inc filed Critical Pivot Bio Inc
Publication of MX2020004344A publication Critical patent/MX2020004344A/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C—CHEMISTRY; METALLURGY
    • C05—FERTILISERS; MANUFACTURE THEREOF
    • C05F—ORGANIC FERTILISERS NOT COVERED BY SUBCLASSES C05B, C05C, e.g. FERTILISERS FROM WASTE OR REFUSE
    • C05F11/00—Other organic fertilisers
    • C05F11/08—Organic fertilisers containing added bacterial cultures, mycelia or the like
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07059—[Protein-PII] uridylyltransferase (2.7.7.59)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y603/00—Ligases forming carbon-nitrogen bonds (6.3)
    • C12Y603/01—Acid-ammonia (or amine)ligases (amide synthases)(6.3.1)
    • C12Y603/01002—Glutamate-ammonia ligase (6.3.1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/22—Klebsiella
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pretreatment Of Seeds And Plants (AREA)

Abstract

Se proporcionan métodos y sistemas para generar y usar una bacteria genéticamente modificada que comprende una modificación en glnD, en donde dicha modificación se selecciona del grupo que consiste en: eliminación del gen completo, eliminación de sustancialmente todo el gen, eliminación de un dominio ACT, eliminación de más del 50 % de un dominio ACT, desactivación de un dominio ACT y desactivación de un dominio UTasa.
MX2020004344A 2017-10-25 2018-10-25 Objetivos genéticos para el direccionamiento de fijación de nitrógeno para mejorar los rasgos de las plantas. MX2020004344A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762577149P 2017-10-25 2017-10-25
PCT/US2018/057613 WO2019084342A1 (en) 2017-10-25 2018-10-25 GENETIC TARGETS FOR TARGETING NITROGEN FIXATION FOR IMPROVING PLANT CHARACTERISTICS

Publications (1)

Publication Number Publication Date
MX2020004344A true MX2020004344A (es) 2020-10-14

Family

ID=66247708

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2020004344A MX2020004344A (es) 2017-10-25 2018-10-25 Objetivos genéticos para el direccionamiento de fijación de nitrógeno para mejorar los rasgos de las plantas.
MX2024010722A MX2024010722A (es) 2017-10-25 2020-07-13 Objetivos geneticos para el direccionamiento de fijacion de nitrogeno para mejorar los rasgos de las plantas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2024010722A MX2024010722A (es) 2017-10-25 2020-07-13 Objetivos geneticos para el direccionamiento de fijacion de nitrogeno para mejorar los rasgos de las plantas.

Country Status (11)

Country Link
US (2) US12151988B2 (es)
EP (1) EP3700879A4 (es)
JP (2) JP2021500907A (es)
KR (1) KR20200087166A (es)
CN (2) CN111527057A (es)
AU (2) AU2018354338B2 (es)
BR (1) BR112020008002A2 (es)
CA (1) CA3080172C (es)
MX (2) MX2020004344A (es)
PH (1) PH12020550489A1 (es)
WO (1) WO2019084342A1 (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014071182A1 (en) 2012-11-01 2014-05-08 Massachusetts Institute Of Technology Directed evolution of synthetic gene cluster
EP3322679A4 (en) 2015-07-13 2019-07-10 Pivot Bio, Inc. METHOD AND COMPOSITIONS FOR IMPROVING PLANT PROPERTIES
AU2016336328A1 (en) 2015-10-05 2018-04-19 Massachusetts Institute Of Technology Nitrogen fixation using refactored nif clusters
UY37566A (es) 2017-01-12 2018-07-31 Pivot Bio Inc Métodos y composiciones para mejorar características en plantas
RU2020109871A (ru) * 2017-08-09 2021-09-14 Пивот Байо, Инк. Способы и композиции для усовершенствования сконструированных микроорганизмов
BR112020008002A2 (pt) 2017-10-25 2020-11-03 Pivot Bio, Inc. alvos gênicos para fixação de nitrogênio para aprimorar traços de plantas
AU2018354221B2 (en) 2017-10-25 2025-04-17 Pivot Bio, Inc. Methods and compositions for improving engineered microbes that fix nitrogen
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
WO2020006064A2 (en) * 2018-06-27 2020-01-02 Pivot Bio, Inc. Agricultural compositions comprising remodeled nitrogen fixing microbes
AU2019302747B2 (en) 2018-07-11 2025-11-20 Pivot Bio, Inc. Temporally and spatially targeted dynamic nitrogen delivery by remodeled microbes
CA3123940A1 (en) 2019-01-07 2020-07-16 Pivot Bio, Inc. Plant colonization assays using natural microbial barcodes
US12281299B2 (en) * 2019-03-19 2025-04-22 Massachusetts Institute Of Technology Control of nitrogen fixation in rhizobia that associate with cereals
BR112021020165A2 (pt) 2019-04-24 2021-12-21 Pivot Bio Inc Alvos gênicos para fixação direcionada de nitrogênio para melhorar traços de planta
EP4069859A1 (en) * 2019-12-03 2022-10-12 Crobio Ltd Genetically engineered microorganisms
WO2021221690A1 (en) 2020-05-01 2021-11-04 Pivot Bio, Inc. Modified bacterial strains for improved fixation of nitrogen
WO2021146209A1 (en) * 2020-01-13 2021-07-22 Pivot Bio, Inc. Consortia of microorganisms for spatial and temporal delivery of nitrogen
WO2021222567A2 (en) 2020-05-01 2021-11-04 Pivot Bio, Inc. Modified bacterial strains for improved fixation of nitrogen
EP4143293A1 (en) 2020-05-01 2023-03-08 Pivot Bio, Inc. Measurement of nitrogen fixation and incorporation
WO2021222643A1 (en) 2020-05-01 2021-11-04 Pivot Bio, Inc. Stable liquid formulations for nitrogen-fixing microorganisms
EP4149245A2 (en) * 2020-05-13 2023-03-22 Pivot Bio, Inc. De-repression of nitrogen fixation in gram-positive microorganisms
WO2022155445A1 (en) * 2021-01-15 2022-07-21 Zymergen Inc. Non-naturally occurring host cells for enhanced plant growth
UY40273A (es) * 2022-05-17 2023-11-30 Bioconsortia Inc Métodos y composiciones para refactorizar los grupos de fijación de nitrógeno
WO2024059180A1 (en) * 2022-09-15 2024-03-21 Zymergen Inc. Soil-based phenotypic screening assays
WO2024107580A1 (en) * 2022-11-14 2024-05-23 Regents Of The University Of Minnesota Genetically modified endophytic diazotrophs and methods of using same
EP4629812A1 (en) * 2022-12-05 2025-10-15 BioConsortia, Inc. Nitrogen-fixing paenibacillus microbes
CN116103214A (zh) * 2023-02-10 2023-05-12 江苏省农业科学院 一种铁限制条件下显著提高hsaf产量的菌株及其应用
CN119213114A (zh) * 2023-03-24 2024-12-27 北京大学 基因工程化固氮细菌
WO2025024750A2 (en) 2023-07-26 2025-01-30 Pivot Bio, Inc. Assessing nitrogenase proteins in rhizosphere to infer microbial functioning
CN117447566A (zh) * 2023-08-01 2024-01-26 华南农业大学 一种植物耐低磷重要基因GmCXIP1-1及其应用
WO2025155521A1 (en) * 2024-01-18 2025-07-24 Pivot Bio, Inc. Host cells for enhanced plant growth
WO2025155518A1 (en) * 2024-01-18 2025-07-24 Pivot Bio, Inc. Host cells for enhanced plant growth
US20250243130A1 (en) 2024-01-31 2025-07-31 Switch Bioworks, Inc. Phosphate sensing microbial gene switch
WO2025166196A1 (en) 2024-01-31 2025-08-07 Switch Bioworks, Inc. Irreversible condition sensitive microbial gene switches
WO2025174810A2 (en) 2024-02-12 2025-08-21 Switch Bioworks, Inc. Density-dependent microbial gene switch
WO2025188506A1 (en) * 2024-03-05 2025-09-12 Bioconsortia, Inc. Novel genome-edited nitrogen fixing bacteria
CN119876173A (zh) * 2024-12-09 2025-04-25 南京农业大学 水稻OsARF1基因的应用

Family Cites Families (240)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1520545A (en) 1924-09-04 1924-12-23 Charles K Morganroth Transmission gearing
US4832728A (en) 1981-09-25 1989-05-23 Melamine Chemicals, Inc. Fertilizer compositions, processes of making them, and pocesses of using them
US4782022A (en) 1984-06-04 1988-11-01 Lubrizol Genetics, Inc. Nitrogen fixation regulator genes
US6548289B1 (en) 1984-12-28 2003-04-15 Land O'lakes, Inc. Biological nitrogen fixation
US5229291A (en) 1985-12-30 1993-07-20 Novo Industri A/S Rhizobia transformants which symbiotically fixes nitrogen in non-legumes, a material for treating seeds of a non-legume plant, non-legume seeds, a non-legume plant and a method for producing rhizobia transconjungants
DK609885D0 (da) 1985-12-30 1985-12-30 Sven Erik Nielsen Fremgangsmaade til modifikation af organismer
CA1335366C (en) 1986-08-19 1995-04-25 Joseph Kloepper Plant growth promoting rhizobacteria for agronomic nonroot crops
EP0292984A2 (en) * 1987-05-29 1988-11-30 The General Hospital Corporation Cloned rhizobium meliloti ntrA (rpoN) gene
JPH01225483A (ja) 1988-03-04 1989-09-08 Takeshi Uozumi 組換え体プラスミド
EP0339830A3 (en) 1988-04-14 1990-01-17 Biotechnica International, Inc. Improved biological nitrogen fixation
DE69033816T2 (de) 1989-02-24 2002-08-08 Monsanto Technology Llc., St. Louis Synthetische pflanzengene und verfahren zu ihrer herstellung
US5188960A (en) 1989-06-27 1993-02-23 Mycogen Corporation Bacillus thuringiensis isolate active against lepidopteran pests, and genes encoding novel lepidopteran-active toxins
US5116506A (en) 1989-06-30 1992-05-26 Oregon State University Support aerated biofilm reactor
US5071743A (en) 1989-10-27 1991-12-10 Her Majesty The Queen In Right Of Canada, As Represented By The National Research Council Of Canada Process for conducting site-directed mutagenesis
US5610044A (en) 1990-10-01 1997-03-11 Lam; Stephen T. Microorganisms with mannopine catabolizing ability
US5427785A (en) 1990-11-21 1995-06-27 Research Seeds, Inc. Rhizosheric bacteria
GB2259302A (en) 1991-09-09 1993-03-10 Anil Kumar Bali Mutant nitrogen fixing bacterium
CA2051071A1 (en) 1991-09-10 1993-03-11 Anil K. Bali Ammonia production
ATE239089T1 (de) 1991-12-24 2003-05-15 Harvard College Gezielte punkt-mutagenese von dna
US5877012A (en) 1993-03-25 1999-03-02 Novartis Finance Corporation Class of proteins for the control of plant pests
FR2718750B1 (fr) 1994-04-19 1996-06-14 Pasteur Institut Protéines recombinantes de l'hémagglutinine filamenteuse de Bordetella, notamment, B. Pertussis, production et application à la production de protéines étrangères ou de principes actifs vaccinants.
EP0818532B1 (en) 1995-03-30 2005-11-16 Takara Bio Inc. Plant promoter and gene expression with the use of the same
US6740506B2 (en) 1995-12-07 2004-05-25 Diversa Corporation End selection in directed evolution
US5789166A (en) 1995-12-08 1998-08-04 Stratagene Circular site-directed mutagenesis
US6083499A (en) 1996-04-19 2000-07-04 Mycogen Corporation Pesticidal toxins
US5916029A (en) 1996-06-26 1999-06-29 Liphatech, Inc. Process for producing seeds coated with a microbial composition
US5780270A (en) 1996-07-17 1998-07-14 Promega Corporation Site-specific mutagenesis and mutant selection utilizing antibiotic-resistant markers encoding gene products having altered substrate specificity
CA2264482A1 (en) 1996-09-06 1998-03-12 The Trustees Of The University Of Pennsylvania An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase
US6114148C1 (en) 1996-09-20 2012-05-01 Gen Hospital Corp High level expression of proteins
US6063756A (en) 1996-09-24 2000-05-16 Monsanto Company Bacillus thuringiensis cryET33 and cryET34 compositions and uses therefor
US6017534A (en) 1996-11-20 2000-01-25 Ecogen, Inc. Hybrid Bacillus thuringiensis δ-endotoxins with novel broad-spectrum insecticidal activity
US6713063B1 (en) 1996-11-20 2004-03-30 Monsanto Technology, Llc Broad-spectrum δ-endotoxins
US5942664A (en) 1996-11-27 1999-08-24 Ecogen, Inc. Bacillus thuringiensis Cry1C compositions toxic to lepidopteran insects and methods for making Cry1C mutants
HUP9701446A1 (hu) 1997-08-27 1999-05-28 Phylaxia-Pharma Gyógyszer-, Oltóanyag és Agrobiológiai Készítményeket Gyártó és Forgalmazó Rt. Eljárás a talaj mikroorganizmus populációjának előnyös kialakítására
US6218188B1 (en) 1997-11-12 2001-04-17 Mycogen Corporation Plant-optimized genes encoding pesticidal toxins
US6033861A (en) 1997-11-19 2000-03-07 Incyte Genetics, Inc. Methods for obtaining nucleic acid containing a mutation
WO2000002996A2 (en) 1998-07-10 2000-01-20 Cornell Research Foundation, Inc. Recombinant constructs and systems for secretion of proteins via type iii secretion systems
CA2703161C (en) 1998-10-23 2011-12-20 Mycogen Corporation Plant-optimized polynucleotides encoding approximately 15 kda and approximately 45 kda pesticidal proteins
US6489542B1 (en) 1998-11-04 2002-12-03 Monsanto Technology Llc Methods for transforming plants to express Cry2Ab δ-endotoxins targeted to the plastids
CZ20013399A3 (cs) 1999-03-23 2002-01-16 Biovation Limited Způsob izolace proteinů a analýzy proteinů, zejména hmotnostní analýzou
DK1220892T3 (da) 1999-07-27 2008-06-09 Food Industry Res & Dev Inst Engineering af metabolisk kontrol
US6248535B1 (en) 1999-12-20 2001-06-19 University Of Southern California Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens
JP3859947B2 (ja) 2000-08-04 2006-12-20 独立行政法人理化学研究所 突然変異導入方法
AU2001283547A1 (en) 2000-08-09 2002-02-18 The Board Of Regents Of The University Of Nebraska Counter selection strategy for gram-negative bacteria
US7879540B1 (en) 2000-08-24 2011-02-01 Promega Corporation Synthetic nucleic acid molecule compositions and methods of preparation
CN1289852A (zh) 2000-09-26 2001-04-04 国家人类基因组南方研究中心 一种人固氮基因同源蛋白及其编码序列
CN1132930C (zh) 2000-11-29 2003-12-31 中国科学院植物研究所 一种固氮菌和含有该固氮菌的生物肥料
CN1129665C (zh) 2000-11-29 2003-12-03 中国科学院植物研究所 一种耐铵工程菌和含有这种工程菌的生物肥料
AR035799A1 (es) 2001-03-30 2004-07-14 Syngenta Participations Ag Toxinas insecticidas aisladas de bacillus thuringiensis y sus usos.
JP2003033174A (ja) 2001-07-10 2003-02-04 Japan Science & Technology Corp 窒素固定能を増強した根粒菌
GB0121126D0 (en) 2001-08-31 2001-10-24 Univ Nottingham Systemic non-nodular endosymbiotic nitrogen fixation in plants
RU2230114C2 (ru) 2001-11-30 2004-06-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Мутантная глутаминсинтетаза, фрагмент днк, штамм escherichia coli - продуцент l-глутамина и способ получения l-аминокислот
US7084331B2 (en) 2002-01-15 2006-08-01 Society for Techno-Innovation of Agriculture Forestry and Fisheries Rice containing endophytic bacteria and method of producing it
US7462760B2 (en) 2002-06-26 2008-12-09 Pioneer Hi-Bred International, Inc. Genes encoding plant protease-resistant pesticidal proteins and method of their use
WO2004003148A2 (en) 2002-06-26 2004-01-08 E.I. Du Pont De Nemours And Company Genes encoding proteins with pesticidal activity
KR100990524B1 (ko) 2002-08-28 2010-10-29 아사히 가세이 파마 가부시키가이샤 신규한 4급 암모늄 화합물
AU2003265637A1 (en) 2002-08-29 2004-03-19 Natalia N. Bogdanova Nucleotide sequences encoding cry1bb proteins for enhanced expression in plants
US20050266541A1 (en) 2002-11-04 2005-12-01 Harrison F. Dillon Methods and compositions for evolving microbial hydrogen production
CN1500801A (zh) * 2002-11-18 2004-06-02 中国农业科学院原子能利用研究所 可提高联合固氮菌固氮水平的基因及其应用
US7491698B2 (en) 2003-01-21 2009-02-17 Dow Agrosciences Llc Mixing and matching TC proteins for pest control
US7355099B2 (en) 2003-02-20 2008-04-08 Athenix Corporation AXMI-004, a delta-endotoxin gene and methods for its use
US20040197917A1 (en) 2003-02-20 2004-10-07 Athenix Corporation AXMI-014, delta-endotoxin gene and methods for its use
US7351881B2 (en) 2003-02-20 2008-04-01 Athenix Corporation AXMI-008, a delta-endotoxin gene and methods for its use
NZ570682A (en) 2003-02-20 2009-08-28 Athenix Corp AXMI-006 a delta-endotoxin gene and methods for its use as a pesticide
US20040210964A1 (en) 2003-02-20 2004-10-21 Athenix Corporation AXMI-009, a delta-endotoxin gene and methods for its use
US20040216186A1 (en) 2003-02-20 2004-10-28 Athenix Corporation AXMI-006, a delta-endotoxin gene and methods for its use
US20040210965A1 (en) 2003-02-20 2004-10-21 Athenix Corporation AXMI-007, a delta-endotoxin gene and methods for its use
CN1254533C (zh) 2003-06-02 2006-05-03 中国农业大学 含多拷贝nifA基因的巴西固氮螺菌DraT－工程菌株
HU0301909D0 (en) 2003-06-23 2003-08-28 Someus Edward Process for solid fermentation of microorganisms bound to bone black carrier amid for production, storage and uses of granular compositions
WO2005019414A2 (en) 2003-07-07 2005-03-03 Monsanto Technology, Llc Insecticidal proteins secreted from bacillus thuringiensis and uses therefor
US7253343B2 (en) 2003-08-28 2007-08-07 Athenix Corporation AXMI-003, a delta-endotoxin gene and methods for its use
US7205450B2 (en) 2003-10-08 2007-04-17 The Regents Of The University Of California DMI1 gene encodes a protein that is required for the early steps of bacterial and fungal symbioses
US20050183161A1 (en) 2003-10-14 2005-08-18 Athenix Corporation AXMI-010, a delta-endotoxin gene and methods for its use
BRPI0507896A (pt) 2004-02-20 2007-07-24 Pionner Hi Bred International lipases e métodos de utilização das mesmas na criação ou no aumento de resistência a insetos em plantas
US20070006340A1 (en) 2004-03-05 2007-01-04 Lang Bruce A Combinations of Cry1Ab and Cry1Fa as an insect resistance management tool
US20090137390A1 (en) 2004-06-30 2009-05-28 Eric Wendell Triplett Materials and methods for enhancing nitrogen fixation in plants
US7938965B2 (en) 2004-07-07 2011-05-10 National University Of Ireland Biofilm reactor
AU2005101078A4 (en) 2004-07-12 2009-04-30 Zebra Holdings Pty Ltd Method and system for promoting microbial nitrogen fixation activity
JP2008510186A (ja) 2004-08-10 2008-04-03 日本板硝子株式会社 Ｌｃｄミラーシステム及び方法
CN1746304A (zh) 2004-09-10 2006-03-15 中国农业科学院生物技术研究所 固氮负调节基因突变的泌铵工程菌的构建及应用
US20060096918A1 (en) 2004-11-09 2006-05-11 Semmens Michael J Biofilm wastewater treatment devices
US7485451B2 (en) 2004-11-18 2009-02-03 Regents Of The University Of California Storage stable compositions of biological materials
MX2007009206A (es) 2005-01-31 2008-02-19 Athenix Corp Axmi-018, axmi-020 y axmi-021, una familia de genes de delta-endotoxina y metodos para su uso.
WO2006098225A1 (ja) 2005-03-14 2006-09-21 Kagoshima University 窒素固定活性の高い根粒を着生する植物の作出法
US7601498B2 (en) 2005-03-17 2009-10-13 Biotium, Inc. Methods of using dyes in association with nucleic acid staining or detection and associated technology
DE602006009239D1 (de) 2005-04-01 2009-10-29 Athenix Corp Axmi-027 delta-endotoxin-genfamilie und verwendungsverfahren dafür
WO2006119457A1 (en) 2005-05-02 2006-11-09 Athenix Corporation Axmi-028 and axmi-029, family of novel delta-endotoxin genes and methods for their use
US9121035B2 (en) 2005-08-31 2015-09-01 Monsanto Technology Llc Insecticidal compositions and methods for making insect-resistant transgenic plants
ES2459617T3 (es) 2006-01-04 2014-05-12 Metabolic Explorer Procedimiento para la preparación de metionina y sus precursores homoserina o succinilhomoserina que utiliza un microorganismo
US20070249018A1 (en) 2006-02-23 2007-10-25 Goutham Vemuri Reduced overflow metabolism and methods of use
AU2007229234B2 (en) 2006-03-22 2013-04-04 Adjuvants Plus Inc. The production and use of endophytes as novel inoculants for promoting enhanced plant vigor, health, growth, yield reducing environmental stress and for reducing dependency on chemical pesticides for pest control
US7449552B2 (en) 2006-04-14 2008-11-11 Pioneer Hi-Bred International, Inc. Bacillus thuringiensis cry gene and protein
US7329736B2 (en) 2006-04-14 2008-02-12 Pioneer Hi-Bred International, Inc. Bacillus thuringiensis cry gene and protein
CA2652377C (en) 2006-05-16 2014-04-22 Monsanto Technology Llc Use of non-agrobacterium bacterial species for plant transformation
AU2007260716B2 (en) 2006-06-14 2013-05-02 BASF Agricultural Solutions Seed US LLC Axmi-031, axmi-039, axmi-040 and axmi-049, a family of delta-endotoxin genes and methods for their use
EP2455391A3 (en) 2006-06-15 2012-08-22 Athenix Corporation A family of pesticidal proteins and methods for their use
EP2057263A1 (en) 2006-06-30 2009-05-13 BioGasol IPR ApS Production of fermentation products in biofilm reactors using microorganisms immobilised on sterilised granular sludge
US8268584B1 (en) 2006-12-01 2012-09-18 University Of Washington Hydrogen production from microbial strains
EA200970559A1 (ru) 2006-12-08 2009-12-30 Пайонир Хай-Бред Интернэшнл, Инк. Новые кристаллические полипептиды из bacillus thuringiensis, кодирующие их полинуклеотиды и композиции этих соединений
US8076142B2 (en) 2006-12-21 2011-12-13 Basf Plant Sciences Gmbh Rooted plant assay system
FR2910230B3 (fr) 2006-12-22 2009-01-23 Pierre Philippe Claude Methodes de biofertilisations pour ameliorer la stabilite des rendements de grandes cultures agronomiques.
WO2008121633A1 (en) 2007-03-28 2008-10-09 Syngenta Participations Ag Insecticidal proteins
US20100267147A1 (en) 2007-04-25 2010-10-21 GM Biosciences, Inc. Site-directed mutagenesis in circular methylated dna
US8609936B2 (en) 2007-04-27 2013-12-17 Monsanto Technology Llc Hemipteran-and coleopteran active toxin proteins from Bacillus thuringiensis
JP4686791B2 (ja) 2007-07-31 2011-05-25 学校法人日本大学 バイオフィルムの生産方法
EP2020437A1 (en) 2007-08-03 2009-02-04 Commissariat A L'energie Atomique (Nife)-hydrogenases having an improved resistance to dioxygen, process for obtaining them and their applications
EP2201030A2 (en) 2007-10-16 2010-06-30 Athenix Corporation Axmi-066 and axmi-076: delta-endotoxin proteins and methods for their use
WO2009060012A2 (en) 2007-11-06 2009-05-14 Basf Se Plant health compositions comprising a beneficial microorganism and a pesticide
US20090162477A1 (en) 2007-12-21 2009-06-25 Daniel Nadel High yield maize derivatives
BRPI0906761A2 (pt) 2008-01-15 2015-07-14 Univ Michigan State Formulações polimicrobianas para aumentar produtividade de planta
US8518685B2 (en) 2008-03-24 2013-08-27 Tsinghua University Engineered nitrile hydratase-producing bacterium with amidase gene knocked-out, the construction and the use thereof
JP2009232721A (ja) 2008-03-26 2009-10-15 Univ Of Miyazaki エンテロバクター属細菌を用いた植物栽培方法
US8401798B2 (en) 2008-06-06 2013-03-19 Dna Twopointo, Inc. Systems and methods for constructing frequency lookup tables for expression systems
EA020327B1 (ru) 2008-06-25 2014-10-30 Атеникс Корпорейшн Гены токсинов и способы их применения
WO2010003065A2 (en) 2008-07-02 2010-01-07 Athenix Corporation Axmi-115, axmi-113, axmi-005, axmi-163 and axmi-184: insecticidal proteins and methods for their use
CN101328477A (zh) 2008-07-23 2008-12-24 中国人民解放军军事医学科学院生物工程研究所 一种双向筛选系统及其应用
US8084416B2 (en) 2008-12-23 2011-12-27 Athenix Corp. AXMI-150 delta-endotoxin gene and methods for its use
WO2010080184A1 (en) 2009-01-09 2010-07-15 Syracuse University System and method for the heterologous expression of polyketide synthase gene clusters
MX2011007329A (es) 2009-01-23 2011-08-12 Pioneer Hi Bred Int Gen bacillus thuringiensis novedoso con actividad lepidoptera.
MX2011008246A (es) 2009-02-05 2011-09-06 Athenix Corp Genes de delta endotoxina variante axmi.r1 y metodos de uso de los mismos.
EP2395096B1 (en) 2009-02-09 2014-04-09 Kyowa Hakko Bio Co., Ltd. Process for producing L-amino acids
MX2011009496A (es) 2009-03-11 2011-10-14 Athenix Corp Axmi-001, axmi-002, axmi-030, axmi-035 y axmi-045: genes de toxina y metodos para su uso.
WO2010105226A2 (en) 2009-03-13 2010-09-16 University Of Washington Endophytic yeast strains, methods for ethanol and xylitol production, methods for biological nitrogen fixation, and a genetic source for improvement of industrial strains
WO2010109436A1 (en) 2009-03-25 2010-09-30 Carepro Bioscience (P) Ltd Microbial formulation for widespread uesd in agricultural practices
CA2758885C (en) 2009-04-17 2018-09-11 Dow Agrosciences Llc Dig-3 insecticidal cry toxins
US8481026B1 (en) 2009-04-17 2013-07-09 Peter J. Woodruff Bacteria with increased trehalose production and method for using the same in bioremediation
US8334366B1 (en) 2009-04-29 2012-12-18 The United States Of America, As Represented By The Secretary Of Agriculture Mutant lycotoxin-1 peptide sequences for insecticidal and cell membrane altering properties
MX2011013675A (es) 2009-06-16 2012-01-20 Dow Agrosciences Llc Toxinas cry dig-11 insecticidas.
WO2011002992A1 (en) 2009-07-02 2011-01-06 Athenix Corp. Axmi-205 pesticidal gene and methods for its use
WO2011029002A2 (en) 2009-09-03 2011-03-10 Advanced Biological Marketing Herbicide-resistant inoculant strains
MX2012002951A (es) 2009-09-11 2012-07-17 Valent Biosciences Corp Nuevo aislado de bacillus thuringiensis.
CN102041241A (zh) 2009-10-20 2011-05-04 中国农业科学院生物技术研究所 高效泌铵的联合固氮菌株
NZ601092A (en) 2009-12-16 2014-09-26 Dow Agrosciences Llc Combined use of cry1ca and cry1fa proteins for insect resistance management
PH12012501437A1 (en) 2009-12-16 2012-10-22 Dow Agrosciences Llc Combined use of vip3ab and cry1fa for management of resistant insects
NZ601105A (en) 2009-12-16 2014-10-31 Dow Agrosciences Llc Insecticidal protein combination comprising cry1ab and cry2aa for controlling european corn borer, and methods for insect resistance management
KR101841297B1 (ko) 2009-12-16 2018-03-22 다우 아그로사이언시즈 엘엘씨 곤충 내성 관리를 위한 ｃｒｙ1ｂｅ와 조합된 ｃｒｙ1ａｂ의 용도
WO2011075587A1 (en) 2009-12-16 2011-06-23 Dow Agrosciences Llc Combined use of cry1da and cry1fa proteins for insect resistance management
WO2011084622A1 (en) 2009-12-16 2011-07-14 Dow Agrosciences Llc Combined use of cry1ca and cry1ab proteins for insect resistance management
AR079506A1 (es) 2009-12-16 2012-02-01 Dow Agrosciences Llc Uso de cry1da en combinacion de cry1be para el manejo de insectos resistentes
WO2011099019A1 (en) 2010-02-09 2011-08-18 Patel, Babubhai, C. Composition and method of preparation of bacterial based product that fix atmospheric nitrogen from air and makes available to plant
WO2011099024A1 (en) 2010-02-09 2011-08-18 Patel, Babubhai C. Preparation of novel bacterial based product for providing nuitrition essential for promoting plant growth
BR112012020921A2 (pt) 2010-02-18 2015-09-08 Athenix Corp genes de delta-endotoxina axmi218, axmi219, axmi220, axmi226, axmi227, axmi228, axmi229, axmi230 e axmi231 e métodos para sua utilização
AU2011218131B2 (en) 2010-02-18 2016-03-17 BASF Agricultural Solutions Seed US LLC AXMI221z, AXMI222z, AXMI223z, AXMI224z, and AXMI225z delta-endotoxin genes and methods for their use
MX2012012371A (es) 2010-04-23 2014-02-27 Dow Agrosciences Llc Combinaciones que incluyen proteinas cry3aa y cry6aa para prevenir el desarrollo de resistencia en gusanos de la raiz de maiz (diabrotica spp.).
CN101880676A (zh) 2010-05-20 2010-11-10 黑龙江大学 导入nifA基因的大豆根瘤菌基因工程菌株HD-SFH-01的构建方法
US9228240B2 (en) 2010-06-03 2016-01-05 California Institute Of Technology Methods for detecting and quantifying viable bacterial endo-spores
WO2011154960A1 (en) 2010-06-09 2011-12-15 Patel, Babubhai C. Advance material and method of preparation of bacterial formulation using nitrogen fixing bacteria that fix atmoshpheric nitrogen and make available to crop plant
UA111592C2 (uk) 2010-07-07 2016-05-25 Сінгента Партісіпейшнс Аг Спосіб контролю над твердокрилими комахами-шкідниками
CN101899430A (zh) 2010-07-12 2010-12-01 甘肃农业大学 一种高效固氮微生物诱变育种方法
WO2012024176A2 (en) 2010-08-19 2012-02-23 Pioneer Hi-Bred International, Inc. Novel bacillus thuringiensis gene with lepidopteran activity
CA2807375A1 (en) 2010-08-19 2012-02-23 Pioneer Hi-Bred International, Inc. Novel bacillus thuringiensis gene with lepidopteran activity
US20120192605A1 (en) 2010-12-23 2012-08-02 The Ohio State University Fertilizer composition and method
AU2012214420B2 (en) 2011-02-11 2017-03-02 Monsanto Technology Llc Pesticidal nucleic acids and proteins and uses thereof
CN102690808B (zh) 2011-03-23 2017-04-19 北京大学 为真核表达的目的构建原核基因表达岛
BR112013024609B1 (pt) 2011-03-31 2018-11-27 Novozymes Biologicals, Inc. composição, e, método para intensificar o crescimento da planta
MX346662B (es) 2011-04-07 2017-03-27 Monsanto Technology Llc Familia de toxinas inhibidoras de insectos activas contra insectos hemipteros y lepidopteros.
US8513494B2 (en) 2011-04-08 2013-08-20 Chunren Wu Plants and seeds of spring canola variety SCV695971
WO2012142116A2 (en) 2011-04-11 2012-10-18 Targeted Growth, Inc. Identification and use of krp mutants in wheat
WO2012154651A2 (en) 2011-05-06 2012-11-15 The Research Foundation Of State University Of New York Molecular roadblocks for rpon binding sites
WO2012162533A2 (en) 2011-05-25 2012-11-29 Sam Houston State University Bioremediation reactor systems
US20130005590A1 (en) 2011-06-06 2013-01-03 The Regents Of The University Of California Synthetic biology tools
CA2838955C (en) 2011-06-16 2023-10-24 The Regents Of The University Of California Synthetic gene clusters
US9279139B2 (en) 2011-06-21 2016-03-08 University Of Guelph Media comprising a glutamine biosensor and methods of use thereof
CN103974972B (zh) 2011-07-28 2018-05-22 阿森尼克斯公司 Axmi270毒素基因及其使用方法
CN103975065B (zh) 2011-07-29 2018-08-10 阿森尼克斯公司 Axmi279杀虫基因及其使用方法
CN102417882A (zh) * 2011-10-25 2012-04-18 中国农业科学院生物技术研究所 固氮斯氏假单胞菌A1501 rpoN基因的表达方法
BR112014010650B1 (pt) 2011-11-04 2020-12-22 Terragen Holdings Limited composições fertilizantes que compreendem inoculantes microbianos e métodos que utilizam as mesmas
AR083981A1 (es) 2011-11-24 2013-04-10 Consejo Nac Invest Cient Tec Cepa de bacteria recombinante fijadora de nitrogeno, inoculo que la contiene y metodos de aplicacion
CN104204211B (zh) 2012-03-03 2017-07-04 科技部生物技术局 重组固氮微生物及其用途
MY169690A (en) 2012-03-21 2019-05-13 Temasek Life Sciences Laboratory Ltd Nitrogen-fixing bacterial inoculant for improvement of crop productivity and reduction of nitrous oxide emission
KR102095976B1 (ko) 2012-05-30 2020-04-02 바이엘 크롭사이언스 악티엔게젤샤프트 생물학적 방제제 및 살곤충제를 포함하는 조성물
CN104470359B (zh) 2012-05-30 2017-05-24 拜尔农作物科学股份公司 包括一种生物防治剂和一种杀虫剂的组合物
WO2014042517A2 (en) 2012-09-14 2014-03-20 Universiti Putra Malaysia Biofertilizer
DK3502235T3 (da) 2012-09-19 2025-09-22 Bioconsortia Inc Fremgangsmåder til screening for mikroorganismer, der overfører gavnlige egenskaber til planter
WO2014071182A1 (en) 2012-11-01 2014-05-08 Massachusetts Institute Of Technology Directed evolution of synthetic gene cluster
JP6024963B2 (ja) 2012-11-13 2016-11-16 国立大学法人東京農工大学 新規バチルス属窒素固定細菌、植物生育促進剤、及び植物の栽培方法
EP4234696A3 (en) 2012-12-12 2023-09-06 The Broad Institute Inc. Crispr-cas component systems, methods and compositions for sequence manipulation
RU2723946C2 (ru) 2013-02-05 2020-06-18 Юниверсити Оф Сэскэтчевэн Эндофитные микробные симбионты в пренатальном уходе за растениями
US9234213B2 (en) 2013-03-15 2016-01-12 System Biosciences, Llc Compositions and methods directed to CRISPR/Cas genomic engineering systems
AU2014235968B2 (en) 2013-03-21 2018-05-24 Ospedale San Raffaele Srl Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases
WO2014201044A2 (en) 2013-06-10 2014-12-18 The Regents Of The University Of California Plant growth-promoting microorganisms and methods of use thereof
CN103451130B (zh) 2013-07-25 2014-11-26 中国农业大学 一种固氮基因簇及其应用
JP6267073B2 (ja) 2013-07-26 2018-01-24 株式会社前川製作所 Ｅｓｃｈｅｒｉｃｈｉａ属細菌の新規農業用途
JP6241916B2 (ja) 2013-08-18 2017-12-06 国立大学法人島根大学 サツマイモの栽培方法
CA2926731C (en) 2013-10-25 2022-08-30 Asilomar Bio, Inc. Strigolactone formulations and uses thereof
EP3076791B1 (en) 2013-12-04 2021-01-27 Newleaf Symbiotics, Inc. Methods for improving corn yield
JP6296776B2 (ja) 2013-12-16 2018-03-20 京都府 バイオ肥料の製造方法
CA2883596A1 (en) 2014-02-26 2015-08-26 Bioponix Technologies Inc. Continuous bioprocess for organic greenhouse agriculture
JP6489676B2 (ja) 2014-03-17 2019-03-27 国立大学法人名古屋大学 生物窒素固定制御因子及びその利用
ES2805000T3 (es) 2014-04-17 2021-02-10 Glaxosmithkline Biologicals Sa Células huéspedes modificadas y usos de las mismas
US20170086402A1 (en) 2014-05-23 2017-03-30 Bioconsortia, Inc. Integrated plant breeding methods for complementary pairings of plants and microbial consortia
WO2015184016A2 (en) 2014-05-27 2015-12-03 The Broad Institute, Inc. High-thoughput assembly of genetic elements
BR112016028961B1 (pt) 2014-06-10 2023-04-11 Afyx Therapeutics A/S Composição compreendendo fibras eletrotorcidas, seu método de preparação e kit
GB201413335D0 (en) 2014-07-28 2014-09-10 Azotic Technologies Ltd Agricultural methods
GB201413333D0 (en) 2014-07-28 2014-09-10 Azotic Technologies Ltd Plant inoculation
US9800220B2 (en) 2014-09-24 2017-10-24 Intel Corporation Audio system with noise interference mitigation
WO2016100727A1 (en) 2014-12-18 2016-06-23 The Regents Of The University Of California Recombinantly engineered diazotrophs for whole cell hydrocarbon production and methods for making and using them
WO2016114973A1 (en) 2015-01-15 2016-07-21 Pioneer Hi Bred International, Inc Insecticidal proteins and methods for their use
EP4147575A1 (en) 2015-02-09 2023-03-15 BioConsortia, Inc. Agriculturally beneficial microbes, microbial compositions, and consortia
US9796957B2 (en) 2015-03-11 2017-10-24 Regents Of The University Of Minnesota Genetically modified diazotrophs and methods of using same
FR3033790B1 (fr) 2015-03-19 2018-05-04 Universite Claude Bernard Lyon I Utilisation de proanthocyanidines pour limiter la denitrification
US10913939B2 (en) 2015-04-01 2021-02-09 Monsanto Technology Llc Compositions and methods for expression of nitrogenase in plant cells
MX2017013864A (es) 2015-05-01 2018-04-24 Indigo Agriculture Inc Composiciones endofitas en complejo aisladas y metodos para mejorar los rasgos de plantas.
NL2014777B1 (en) 2015-05-07 2017-01-26 Ibema Biezenmortel B V Nitrifying micro-organisms for fertilisation.
CA2985729C (en) 2015-05-11 2023-05-09 Mybiotics Pharma Ltd Systems and methods for growing a biofilm of probiotic bacteria on solid particles for colonization of bacteria in the gut
JP6887390B2 (ja) 2015-06-05 2021-06-16 サステナブル オーガニック ソリューションズ ピーティーワイ リミテッドＳｕｓｔａｉｎａｂｌｅ Ｏｒｇａｎｉｃ Ｓｏｌｕｔｉｏｎｓ Ｐｔｙ Ｌｔｄ 植物の生長を向上させるための方法、コーティングおよび細菌ｓｏｓ３株
EP3322679A4 (en) 2015-07-13 2019-07-10 Pivot Bio, Inc. METHOD AND COMPOSITIONS FOR IMPROVING PLANT PROPERTIES
WO2017042833A1 (en) 2015-09-11 2017-03-16 Zydex Industries Pvt. Ltd. Bio-fertilizer composition
AU2016336328A1 (en) 2015-10-05 2018-04-19 Massachusetts Institute Of Technology Nitrogen fixation using refactored nif clusters
US10131585B2 (en) 2015-10-19 2018-11-20 California Institute Of Technology Hopanoids producing bacteria and related biofertilizers, compositions, methods and systems
TR201513059A1 (tr) 2015-10-20 2019-01-21 Ibrahim Isildak Bi̇r bi̇yogübre formülasyonu
AU2016378742A1 (en) 2015-12-21 2018-07-12 Indigo Ag, Inc. Endophyte compositions and methods for improvement of plant traits in plants of agronomic importance
EP3231874A1 (en) 2016-04-14 2017-10-18 Curetis GmbH Using the full repertoire of genetic information from bacterial genomes and plasmids for improved genetic resistance tests
ITUA20163807A1 (it) 2016-05-25 2017-11-25 Univ Degli Studi Di Foggia Metodo per la produzione di biofilm microbici probiotici e relativi usi
CN106086042A (zh) 2016-06-30 2016-11-09 上海交通大学 固氮菌铵载体基因、突变体、固氮菌铵载体突变株及应用
US20190269138A1 (en) 2016-10-28 2019-09-05 Bayer Cropscience Lp Mutants of bacillus and methods for their use
UY37566A (es) 2017-01-12 2018-07-31 Pivot Bio Inc Métodos y composiciones para mejorar características en plantas
CN106658654A (zh) 2017-01-22 2017-05-10 北京佰才邦技术有限公司 软sim的控制方法及用户终端
RU2020109871A (ru) 2017-08-09 2021-09-14 Пивот Байо, Инк. Способы и композиции для усовершенствования сконструированных микроорганизмов
US10525318B2 (en) 2017-09-12 2020-01-07 Edmond J. Dougherty Timing display device
BR112020008002A2 (pt) 2017-10-25 2020-11-03 Pivot Bio, Inc. alvos gênicos para fixação de nitrogênio para aprimorar traços de plantas
AU2018354221B2 (en) 2017-10-25 2025-04-17 Pivot Bio, Inc. Methods and compositions for improving engineered microbes that fix nitrogen
JP2021510296A (ja) 2018-01-10 2021-04-22 バイエル クロップサイエンス エルピーＢａｙｅｒ Ｃｒｏｐｓｃｉｅｎｃｅ Ｌｐ 改良された微生物とその製造方法
BR112020026676A2 (pt) 2018-06-27 2021-08-03 Pivot Bio, Inc. remodelação microbiana guiada, uma plataforma para a melhoria racional de espécies microbianas para agricultura
WO2020006064A2 (en) 2018-06-27 2020-01-02 Pivot Bio, Inc. Agricultural compositions comprising remodeled nitrogen fixing microbes
AU2019302747B2 (en) 2018-07-11 2025-11-20 Pivot Bio, Inc. Temporally and spatially targeted dynamic nitrogen delivery by remodeled microbes
US12365945B2 (en) 2018-07-25 2025-07-22 Convergent Genomics, Inc. Urinary microbiomic profiling
MX2021003306A (es) 2018-09-21 2021-05-13 Pivot Bio Inc Metodos y composiciones para mejorar la solubilizacion de fosfato.
WO2020092940A1 (en) 2018-11-01 2020-05-07 Pivot Bio, Inc. Biofilm compositions with improved stability for nitrogen fixing microbial products
CN117887620A (zh) 2018-12-07 2024-04-16 皮沃特生物股份有限公司 用于固氮微生物产品的具有提高的稳定性的聚合物组合物
CN113825393A (zh) 2018-12-21 2021-12-21 皮沃特生物股份有限公司 改善植物性状的方法、组合物和培养基
CA3123940A1 (en) 2019-01-07 2020-07-16 Pivot Bio, Inc. Plant colonization assays using natural microbial barcodes
MX2021009391A (es) 2019-02-05 2021-12-10 Pivot Bio Inc Mejora de la consistencia del rendimiento de la cosecha mediante la fijación biológica del nitrógeno.
US12281299B2 (en) 2019-03-19 2025-04-22 Massachusetts Institute Of Technology Control of nitrogen fixation in rhizobia that associate with cereals
BR112021020165A2 (pt) 2019-04-24 2021-12-21 Pivot Bio Inc Alvos gênicos para fixação direcionada de nitrogênio para melhorar traços de planta
EP3959302A4 (en) 2019-04-25 2023-06-21 Pivot Bio, Inc. High-throughput methods for isolating and characterizing ammonium-excreting mutant libraries generated by chemical mutagenesis
WO2021113352A1 (en) 2019-12-04 2021-06-10 Pivot Bio, Inc. System to deliver a solution with a biological product in a planter assembly
WO2021146209A1 (en) 2020-01-13 2021-07-22 Pivot Bio, Inc. Consortia of microorganisms for spatial and temporal delivery of nitrogen
US20230257317A1 (en) 2020-05-01 2023-08-17 Pivot Bio, Inc. Modified bacterial strains for improved fixation of nitrogen
EP4149245A2 (en) 2020-05-13 2023-03-22 Pivot Bio, Inc. De-repression of nitrogen fixation in gram-positive microorganisms

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