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MX2019015413A - Metodo. - Google Patents

Metodo.

Info

Publication number
MX2019015413A
MX2019015413A MX2019015413A MX2019015413A MX2019015413A MX 2019015413 A MX2019015413 A MX 2019015413A MX 2019015413 A MX2019015413 A MX 2019015413A MX 2019015413 A MX2019015413 A MX 2019015413A MX 2019015413 A MX2019015413 A MX 2019015413A
Authority
MX
Mexico
Prior art keywords
plant
modulating
tobacco
nic1
erf
Prior art date
Application number
MX2019015413A
Other languages
English (en)
Inventor
Matthew Edward Humphry
Shengming Yang
Qiulin Qin
Original Assignee
Univ Kentucky Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kentucky Res Found filed Critical Univ Kentucky Res Found
Publication of MX2019015413A publication Critical patent/MX2019015413A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
    • A01H5/12Leaves
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H6/00Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
    • A01H6/82Solanaceae, e.g. pepper, tobacco, potato, tomato or eggplant
    • A01H6/823Nicotiana, e.g. tobacco
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B13/00Tobacco for pipes, for cigars, e.g. cigar inserts, or for cigarettes; Chewing tobacco; Snuff
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10Chemical features of tobacco products or tobacco substitutes
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18Treatment of tobacco products or tobacco substitutes
    • A24B15/20Biochemical treatment
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18Treatment of tobacco products or tobacco substitutes
    • A24B15/24Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
    • A24B15/241Extraction of specific substances
    • A24B15/245Nitrosamines
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04Plant cells or tissues
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Developmental Biology & Embryology (AREA)
  • Physiology (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Manufacture Of Tobacco Products (AREA)

Abstract

La presente invención proporciona un método para modular el contenido de alcaloides de una planta (por ejemplo, una planta de tabaco), el método comprende modificar dicha planta modulando la actividad o expresión de al menos un gen Nic1 ERF. La presente invención también proporciona el uso de al menos un gen Nic1 ERF para modular el contenido de alcaloides de una planta, así como células de tabaco, plantas, materiales de propagación de plantas, hojas cosechadas, tabacos procesados o productos de tabaco obtenibles de acuerdo con la invención.
MX2019015413A 2017-06-23 2018-06-21 Metodo. MX2019015413A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762524216P 2017-06-23 2017-06-23
PCT/US2018/038679 WO2018237107A1 (en) 2017-06-23 2018-06-21 Method

Publications (1)

Publication Number Publication Date
MX2019015413A true MX2019015413A (es) 2020-07-20

Family

ID=62909617

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2019015413A MX2019015413A (es) 2017-06-23 2018-06-21 Metodo.
MX2023005683A MX2023005683A (es) 2017-06-23 2019-12-17 Metodo.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2023005683A MX2023005683A (es) 2017-06-23 2019-12-17 Metodo.

Country Status (11)

Country Link
US (2) US12139718B2 (es)
EP (1) EP3642346A1 (es)
JP (3) JP7366758B2 (es)
CN (1) CN111315891A (es)
AR (1) AR112113A1 (es)
BR (1) BR112019027710A2 (es)
CA (2) CA3067842C (es)
IL (1) IL271516B2 (es)
MX (2) MX2019015413A (es)
PH (1) PH12019550294A1 (es)
WO (1) WO2018237107A1 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4218404A3 (en) 2015-06-26 2023-09-06 Altria Client Services LLC Compositions and methods for producing tobacco plants and products having altered alkaloid levels
CA3067842C (en) * 2017-06-23 2025-11-04 University Of Kentucky Research Foundation METHODS FOR MODULATING THE ALKALOID CONTENT OF A PLANT OR PART OF THAT PLANT
CN111836539A (zh) * 2018-01-12 2020-10-27 奥驰亚客户服务有限公司 用于产生烟草植物和具有经过改变的生物碱水平的产品的组合物和方法
BR112021001364A2 (pt) 2018-07-26 2021-04-20 Altria Client Services Llc composições e métodos à base de engenharia de pmt para produzir plantas de tabaco e produtos tendo níveis de alcaloides alterados
EP3914069A1 (en) 2019-01-24 2021-12-01 Altria Client Services LLC Tobacco plants comprising reduced nicotine and reduced tobacco specific nitrosamines
GB201909562D0 (en) * 2019-07-03 2019-08-14 British American Tobacco Investments Ltd Method
GB201909563D0 (en) 2019-07-03 2019-08-14 British American Tobacco Investments Ltd Method
MX2022001491A (es) * 2019-08-05 2022-04-20 Univ Virginia Patent Foundation Factor de transcripcion nterf221 y metodos de uso del mismo.
JP2022552261A (ja) 2019-10-10 2022-12-15 アルトリア クライアント サーヴィシーズ リミテッド ライアビリティ カンパニー 変化したアルカロイドレベルを有するタバコ植物およびタバコ製品を作製するためのqpt操作に基づく組成物および方法
CN114745946B (zh) 2019-10-10 2024-03-08 奥驰亚客户服务有限公司 浅黄色基因座及其在烟草中的应用
EP4041898A1 (en) 2019-10-10 2022-08-17 Altria Client Services LLC Compositions and methods for producing tobacco plants and products having altered alkaloid levels with desirable leaf quality via manipulating leaf quality genes
CN110669772A (zh) * 2019-10-22 2020-01-10 云南省烟草农业科学研究院 一种烟草新烟碱合成调控基因NtERF91的克隆和应用
CN110592103A (zh) * 2019-10-22 2019-12-20 云南省烟草农业科学研究院 一种烟草假木贼碱合成调控基因NtERF91的克隆和应用
US20240218386A1 (en) 2019-12-03 2024-07-04 Altria Client Services Llc Compositions and Methods for Producing Tobacco Plants and Products Having Altered Alkaloid Levels
WO2021154738A1 (en) 2020-01-27 2021-08-05 Altria Client Services Llc Compositions and methods based on pmt engineering for producing tobacco plants and products having altered alkaloid levels
CN116096902A (zh) * 2020-04-09 2023-05-09 R·J·雷诺兹烟草公司 用于调节烟草中尼古丁水平的方法
CN119138333A (zh) * 2020-06-03 2024-12-17 奥驰亚客户服务有限公司 用于生产具有改变的生物碱水平的烟草植物和制品的组合物和方法
US20250215443A1 (en) 2022-02-03 2025-07-03 Nicoventures Trading Limited Method of modulating alkaloid content in tobacco plants
US20250137006A1 (en) 2022-02-03 2025-05-01 Nicoventures Trading Limited Method of modulating alkaloid content in tobacco plants
WO2023148475A1 (en) 2022-02-04 2023-08-10 Nicoventures Trading Limited Method of modulating alkaloid content in tobacco plants
GB202205149D0 (en) 2022-04-07 2022-05-25 Nicoventures Trading Ltd Method
GB202205148D0 (en) 2022-04-07 2022-05-25 Nicoventures Trading Ltd Method
GB202205561D0 (en) 2022-04-14 2022-06-01 Nicoventures Trading Ltd Method
GB202205562D0 (en) 2022-04-14 2022-06-01 Nicoventures Trading Ltd Method
GB202206109D0 (en) 2022-04-27 2022-06-08 Nicoventures Trading Ltd Method
GB202206107D0 (en) 2022-04-27 2022-06-08 Nicoventures Trading Ltd Method
WO2023230433A1 (en) 2022-05-23 2023-11-30 Altria Client Services Llc Methods and compositions for regulating alkaloids in tobacco field
CN119948047A (zh) 2022-08-05 2025-05-06 奥驰亚客户服务有限公司 用于调控烟草中的生物碱的方法和组合物
WO2025147663A2 (en) 2024-01-05 2025-07-10 Altria Client Services Llc Methods and compositions for modulating trichome density and flavor molecule secretion

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2162738A (en) 1937-08-18 1939-06-20 Clarence E Mccoy Extracting nicotine from tobacco
NL8300698A (nl) 1983-02-24 1984-09-17 Univ Leiden Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten.
US4643290A (en) 1985-12-04 1987-02-17 Sundstrand Corporation Bi-directional overtravel stop
ATE57390T1 (de) 1986-03-11 1990-10-15 Plant Genetic Systems Nv Durch gentechnologie erhaltene und gegen glutaminsynthetase-inhibitoren resistente pflanzenzellen.
GB8626862D0 (en) 1986-11-11 1986-12-10 Jefferson R A Gene fusion
GB8825402D0 (en) 1988-10-31 1988-11-30 Cambridge Advanced Tech Sulfonamide resistance genes
KR100225087B1 (ko) 1990-03-23 1999-10-15 한스 발터라벤 피타아제의 식물내 발현
GB9524350D0 (en) 1995-11-29 1996-01-31 Lynxvale Ltd Enhancer-increased gene expression in plants
ES2539616T3 (es) 2005-10-18 2015-07-02 Precision Biosciences Meganucleasa diseñada racionalmente con afinidad de formación de dímeros alterada
CN104911204B (zh) * 2007-05-25 2019-01-01 22世纪有限责任公司 编码调节生物碱合成之转录因子的核酸序列及其在改良植物代谢中的应用
AU2008318430A1 (en) 2007-10-31 2009-05-07 Precision Biosciences, Inc. Rationally-designed single-chain meganucleases with non-palindromic recognition sequences
EP2206723A1 (en) 2009-01-12 2010-07-14 Bonas, Ulla Modular DNA-binding domains
GB0903346D0 (en) 2009-02-27 2009-04-08 Cambridge Advanced Tech Transgenic Plants
TR201815882T4 (tr) 2009-12-10 2018-11-21 Univ Iowa State Res Found Inc Tal efektörü aracılı dna modifikasyonu.
KR102060691B1 (ko) 2011-09-06 2020-02-11 브리티시 아메리칸 토바코 (인베스트먼츠) 리미티드 가열식 흡연가능 재료
CA2890160A1 (en) 2012-10-31 2014-05-08 Cellectis Coupling herbicide resistance with targeted insertion of transgenes in plants
SG10201707569YA (en) 2012-12-12 2017-10-30 Broad Inst Inc Delivery, Engineering and Optimization of Systems, Methods and Compositions for Sequence Manipulation and Therapeutic Applications
GB2515502A (en) 2013-06-25 2014-12-31 British American Tobacco Co Apparatus and method
EP4218404A3 (en) 2015-06-26 2023-09-06 Altria Client Services LLC Compositions and methods for producing tobacco plants and products having altered alkaloid levels
CA3067842C (en) * 2017-06-23 2025-11-04 University Of Kentucky Research Foundation METHODS FOR MODULATING THE ALKALOID CONTENT OF A PLANT OR PART OF THAT PLANT

Also Published As

Publication number Publication date
CN111315891A (zh) 2020-06-19
AR112113A1 (es) 2019-09-18
MX2023005683A (es) 2023-05-26
PH12019550294A1 (en) 2021-01-04
IL271516B1 (en) 2024-06-01
CA3248884A1 (en) 2025-11-29
IL271516A (en) 2020-02-27
US20200291413A1 (en) 2020-09-17
WO2018237107A1 (en) 2018-12-27
US12139718B2 (en) 2024-11-12
CA3067842C (en) 2025-11-04
EP3642346A1 (en) 2020-04-29
JP7366758B2 (ja) 2023-10-23
JP7470139B2 (ja) 2024-04-17
JP2020524508A (ja) 2020-08-20
JP2024045195A (ja) 2024-04-02
CA3067842A1 (en) 2018-12-27
JP2022078014A (ja) 2022-05-24
US20250122517A1 (en) 2025-04-17
IL271516B2 (en) 2024-10-01
BR112019027710A2 (pt) 2020-08-18

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