AR112113A1 - Método para modular el contenido de alcaloides de una planta - Google Patents
Método para modular el contenido de alcaloides de una plantaInfo
- Publication number
- AR112113A1 AR112113A1 ARP180101737A ARP180101737A AR112113A1 AR 112113 A1 AR112113 A1 AR 112113A1 AR P180101737 A ARP180101737 A AR P180101737A AR P180101737 A ARP180101737 A AR P180101737A AR 112113 A1 AR112113 A1 AR 112113A1
- Authority
- AR
- Argentina
- Prior art keywords
- plant
- alkaloid content
- modulate
- tobacco
- nic1
- Prior art date
Links
- 229930013930 alkaloid Natural products 0.000 title abstract 3
- 150000003797 alkaloid derivatives Chemical class 0.000 title abstract 3
- 241000196324 Embryophyta Species 0.000 abstract 5
- 235000002637 Nicotiana tabacum Nutrition 0.000 abstract 3
- 101150094177 Erf gene Proteins 0.000 abstract 2
- PWHVEHULNLETOV-UHFFFAOYSA-N Nic-1 Natural products C12OC2C2(O)CC=CC(=O)C2(C)C(CCC2=C3)C1C2=CC=C3C(C)C1OC(O)C2(C)OC2(C)C1 PWHVEHULNLETOV-UHFFFAOYSA-N 0.000 abstract 2
- 241000208125 Nicotiana Species 0.000 abstract 2
- 244000061176 Nicotiana tabacum Species 0.000 abstract 1
- 235000019505 tobacco product Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
- A01H5/12—Leaves
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
- A01H6/82—Solanaceae, e.g. pepper, tobacco, potato, tomato or eggplant
- A01H6/823—Nicotiana, e.g. tobacco
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B13/00—Tobacco for pipes, for cigars, e.g. cigar inserts, or for cigarettes; Chewing tobacco; Snuff
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/20—Biochemical treatment
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
- A24B15/241—Extraction of specific substances
- A24B15/245—Nitrosamines
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/04—Plant cells or tissues
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Botany (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Developmental Biology & Embryology (AREA)
- Physiology (AREA)
- Environmental Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Nutrition Science (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Manufacture Of Tobacco Products (AREA)
Abstract
Método para modular el contenido de alcaloides de una planta (por ejemplo, una planta de tabaco), donde dicho método comprende modificar dicha planta mediante modulación de la actividad o expresión de por lo menos un gen Nic1 ERF. También se provee el uso de por lo, menos un gen Nic1 ERF para modular el contenido de alcaloides de una planta, así como células de tabaco, plantas, materiales de propagación vegetal, hojas cosechadas, tabacos procesados o productos de tabaco que se pueden obtener de acuerdo con la presente.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762524216P | 2017-06-23 | 2017-06-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR112113A1 true AR112113A1 (es) | 2019-09-18 |
Family
ID=62909617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP180101737A AR112113A1 (es) | 2017-06-23 | 2018-06-21 | Método para modular el contenido de alcaloides de una planta |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US12139718B2 (es) |
| EP (1) | EP3642346A1 (es) |
| JP (3) | JP7366758B2 (es) |
| CN (1) | CN111315891A (es) |
| AR (1) | AR112113A1 (es) |
| BR (1) | BR112019027710A2 (es) |
| CA (2) | CA3067842C (es) |
| IL (1) | IL271516B2 (es) |
| MX (2) | MX2019015413A (es) |
| PH (1) | PH12019550294A1 (es) |
| WO (1) | WO2018237107A1 (es) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4218404A3 (en) | 2015-06-26 | 2023-09-06 | Altria Client Services LLC | Compositions and methods for producing tobacco plants and products having altered alkaloid levels |
| CA3067842C (en) * | 2017-06-23 | 2025-11-04 | University Of Kentucky Research Foundation | METHODS FOR MODULATING THE ALKALOID CONTENT OF A PLANT OR PART OF THAT PLANT |
| CN111836539A (zh) * | 2018-01-12 | 2020-10-27 | 奥驰亚客户服务有限公司 | 用于产生烟草植物和具有经过改变的生物碱水平的产品的组合物和方法 |
| BR112021001364A2 (pt) | 2018-07-26 | 2021-04-20 | Altria Client Services Llc | composições e métodos à base de engenharia de pmt para produzir plantas de tabaco e produtos tendo níveis de alcaloides alterados |
| EP3914069A1 (en) | 2019-01-24 | 2021-12-01 | Altria Client Services LLC | Tobacco plants comprising reduced nicotine and reduced tobacco specific nitrosamines |
| GB201909562D0 (en) * | 2019-07-03 | 2019-08-14 | British American Tobacco Investments Ltd | Method |
| GB201909563D0 (en) | 2019-07-03 | 2019-08-14 | British American Tobacco Investments Ltd | Method |
| MX2022001491A (es) * | 2019-08-05 | 2022-04-20 | Univ Virginia Patent Foundation | Factor de transcripcion nterf221 y metodos de uso del mismo. |
| JP2022552261A (ja) | 2019-10-10 | 2022-12-15 | アルトリア クライアント サーヴィシーズ リミテッド ライアビリティ カンパニー | 変化したアルカロイドレベルを有するタバコ植物およびタバコ製品を作製するためのqpt操作に基づく組成物および方法 |
| CN114745946B (zh) | 2019-10-10 | 2024-03-08 | 奥驰亚客户服务有限公司 | 浅黄色基因座及其在烟草中的应用 |
| EP4041898A1 (en) | 2019-10-10 | 2022-08-17 | Altria Client Services LLC | Compositions and methods for producing tobacco plants and products having altered alkaloid levels with desirable leaf quality via manipulating leaf quality genes |
| CN110669772A (zh) * | 2019-10-22 | 2020-01-10 | 云南省烟草农业科学研究院 | 一种烟草新烟碱合成调控基因NtERF91的克隆和应用 |
| CN110592103A (zh) * | 2019-10-22 | 2019-12-20 | 云南省烟草农业科学研究院 | 一种烟草假木贼碱合成调控基因NtERF91的克隆和应用 |
| US20240218386A1 (en) | 2019-12-03 | 2024-07-04 | Altria Client Services Llc | Compositions and Methods for Producing Tobacco Plants and Products Having Altered Alkaloid Levels |
| WO2021154738A1 (en) | 2020-01-27 | 2021-08-05 | Altria Client Services Llc | Compositions and methods based on pmt engineering for producing tobacco plants and products having altered alkaloid levels |
| CN116096902A (zh) * | 2020-04-09 | 2023-05-09 | R·J·雷诺兹烟草公司 | 用于调节烟草中尼古丁水平的方法 |
| CN119138333A (zh) * | 2020-06-03 | 2024-12-17 | 奥驰亚客户服务有限公司 | 用于生产具有改变的生物碱水平的烟草植物和制品的组合物和方法 |
| US20250215443A1 (en) | 2022-02-03 | 2025-07-03 | Nicoventures Trading Limited | Method of modulating alkaloid content in tobacco plants |
| US20250137006A1 (en) | 2022-02-03 | 2025-05-01 | Nicoventures Trading Limited | Method of modulating alkaloid content in tobacco plants |
| WO2023148475A1 (en) | 2022-02-04 | 2023-08-10 | Nicoventures Trading Limited | Method of modulating alkaloid content in tobacco plants |
| GB202205149D0 (en) | 2022-04-07 | 2022-05-25 | Nicoventures Trading Ltd | Method |
| GB202205148D0 (en) | 2022-04-07 | 2022-05-25 | Nicoventures Trading Ltd | Method |
| GB202205561D0 (en) | 2022-04-14 | 2022-06-01 | Nicoventures Trading Ltd | Method |
| GB202205562D0 (en) | 2022-04-14 | 2022-06-01 | Nicoventures Trading Ltd | Method |
| GB202206109D0 (en) | 2022-04-27 | 2022-06-08 | Nicoventures Trading Ltd | Method |
| GB202206107D0 (en) | 2022-04-27 | 2022-06-08 | Nicoventures Trading Ltd | Method |
| WO2023230433A1 (en) | 2022-05-23 | 2023-11-30 | Altria Client Services Llc | Methods and compositions for regulating alkaloids in tobacco field |
| CN119948047A (zh) | 2022-08-05 | 2025-05-06 | 奥驰亚客户服务有限公司 | 用于调控烟草中的生物碱的方法和组合物 |
| WO2025147663A2 (en) | 2024-01-05 | 2025-07-10 | Altria Client Services Llc | Methods and compositions for modulating trichome density and flavor molecule secretion |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2162738A (en) | 1937-08-18 | 1939-06-20 | Clarence E Mccoy | Extracting nicotine from tobacco |
| NL8300698A (nl) | 1983-02-24 | 1984-09-17 | Univ Leiden | Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten. |
| US4643290A (en) | 1985-12-04 | 1987-02-17 | Sundstrand Corporation | Bi-directional overtravel stop |
| ATE57390T1 (de) | 1986-03-11 | 1990-10-15 | Plant Genetic Systems Nv | Durch gentechnologie erhaltene und gegen glutaminsynthetase-inhibitoren resistente pflanzenzellen. |
| GB8626862D0 (en) | 1986-11-11 | 1986-12-10 | Jefferson R A | Gene fusion |
| GB8825402D0 (en) | 1988-10-31 | 1988-11-30 | Cambridge Advanced Tech | Sulfonamide resistance genes |
| KR100225087B1 (ko) | 1990-03-23 | 1999-10-15 | 한스 발터라벤 | 피타아제의 식물내 발현 |
| GB9524350D0 (en) | 1995-11-29 | 1996-01-31 | Lynxvale Ltd | Enhancer-increased gene expression in plants |
| ES2539616T3 (es) | 2005-10-18 | 2015-07-02 | Precision Biosciences | Meganucleasa diseñada racionalmente con afinidad de formación de dímeros alterada |
| CN104911204B (zh) * | 2007-05-25 | 2019-01-01 | 22世纪有限责任公司 | 编码调节生物碱合成之转录因子的核酸序列及其在改良植物代谢中的应用 |
| AU2008318430A1 (en) | 2007-10-31 | 2009-05-07 | Precision Biosciences, Inc. | Rationally-designed single-chain meganucleases with non-palindromic recognition sequences |
| EP2206723A1 (en) | 2009-01-12 | 2010-07-14 | Bonas, Ulla | Modular DNA-binding domains |
| GB0903346D0 (en) | 2009-02-27 | 2009-04-08 | Cambridge Advanced Tech | Transgenic Plants |
| TR201815882T4 (tr) | 2009-12-10 | 2018-11-21 | Univ Iowa State Res Found Inc | Tal efektörü aracılı dna modifikasyonu. |
| KR102060691B1 (ko) | 2011-09-06 | 2020-02-11 | 브리티시 아메리칸 토바코 (인베스트먼츠) 리미티드 | 가열식 흡연가능 재료 |
| CA2890160A1 (en) | 2012-10-31 | 2014-05-08 | Cellectis | Coupling herbicide resistance with targeted insertion of transgenes in plants |
| SG10201707569YA (en) | 2012-12-12 | 2017-10-30 | Broad Inst Inc | Delivery, Engineering and Optimization of Systems, Methods and Compositions for Sequence Manipulation and Therapeutic Applications |
| GB2515502A (en) | 2013-06-25 | 2014-12-31 | British American Tobacco Co | Apparatus and method |
| EP4218404A3 (en) | 2015-06-26 | 2023-09-06 | Altria Client Services LLC | Compositions and methods for producing tobacco plants and products having altered alkaloid levels |
| CA3067842C (en) * | 2017-06-23 | 2025-11-04 | University Of Kentucky Research Foundation | METHODS FOR MODULATING THE ALKALOID CONTENT OF A PLANT OR PART OF THAT PLANT |
-
2018
- 2018-06-21 CA CA3067842A patent/CA3067842C/en active Active
- 2018-06-21 AR ARP180101737A patent/AR112113A1/es unknown
- 2018-06-21 EP EP18740703.6A patent/EP3642346A1/en active Pending
- 2018-06-21 WO PCT/US2018/038679 patent/WO2018237107A1/en not_active Ceased
- 2018-06-21 MX MX2019015413A patent/MX2019015413A/es unknown
- 2018-06-21 CN CN201880054539.1A patent/CN111315891A/zh active Pending
- 2018-06-21 JP JP2019570425A patent/JP7366758B2/ja active Active
- 2018-06-21 BR BR112019027710-2A patent/BR112019027710A2/pt unknown
- 2018-06-21 IL IL271516A patent/IL271516B2/en unknown
- 2018-06-21 US US16/625,262 patent/US12139718B2/en active Active
- 2018-06-21 CA CA3248884A patent/CA3248884A1/en active Pending
-
2019
- 2019-12-17 MX MX2023005683A patent/MX2023005683A/es unknown
- 2019-12-18 PH PH12019550294A patent/PH12019550294A1/en unknown
-
2022
- 2022-01-12 JP JP2022002899A patent/JP7470139B2/ja active Active
-
2024
- 2024-01-10 JP JP2024001786A patent/JP2024045195A/ja active Pending
- 2024-09-25 US US18/895,992 patent/US20250122517A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN111315891A (zh) | 2020-06-19 |
| MX2023005683A (es) | 2023-05-26 |
| PH12019550294A1 (en) | 2021-01-04 |
| IL271516B1 (en) | 2024-06-01 |
| CA3248884A1 (en) | 2025-11-29 |
| IL271516A (en) | 2020-02-27 |
| US20200291413A1 (en) | 2020-09-17 |
| WO2018237107A1 (en) | 2018-12-27 |
| US12139718B2 (en) | 2024-11-12 |
| CA3067842C (en) | 2025-11-04 |
| EP3642346A1 (en) | 2020-04-29 |
| JP7366758B2 (ja) | 2023-10-23 |
| JP7470139B2 (ja) | 2024-04-17 |
| JP2020524508A (ja) | 2020-08-20 |
| JP2024045195A (ja) | 2024-04-02 |
| CA3067842A1 (en) | 2018-12-27 |
| MX2019015413A (es) | 2020-07-20 |
| JP2022078014A (ja) | 2022-05-24 |
| US20250122517A1 (en) | 2025-04-17 |
| IL271516B2 (en) | 2024-10-01 |
| BR112019027710A2 (pt) | 2020-08-18 |
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