[go: up one dir, main page]

MX2019010544A - Dispositivo de administracion de farmacos con caracteristica de prevencion de la activacion. - Google Patents

Dispositivo de administracion de farmacos con caracteristica de prevencion de la activacion.

Info

Publication number
MX2019010544A
MX2019010544A MX2019010544A MX2019010544A MX2019010544A MX 2019010544 A MX2019010544 A MX 2019010544A MX 2019010544 A MX2019010544 A MX 2019010544A MX 2019010544 A MX2019010544 A MX 2019010544A MX 2019010544 A MX2019010544 A MX 2019010544A
Authority
MX
Mexico
Prior art keywords
drug administration
administration device
housing
activation prevention
prevention characteristic
Prior art date
Application number
MX2019010544A
Other languages
English (en)
Inventor
Chan James
Frances BOYAVAL Margaux
Stonecipher Brian
KUO Avon
Lee Cameron Allan
Franklin BISCHOFF Maxwell
Allen Flender Gregg
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX2019010544A publication Critical patent/MX2019010544A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1413—Modular systems comprising interconnecting elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/27—General characteristics of the apparatus preventing use
    • A61M2205/276—General characteristics of the apparatus preventing use preventing unwanted use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00—Methods of manufacture, assembly or production

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Un dispositivo de administración de fármacos ponible incluye un inyector que tiene una carcasa, un depósito, una aguja o cánula, un mecanismo de impulsión para impulsar un producto farmacológico fuera del depósito, a través de la aguja o cánula, y hasta un paciente, y un mecanismo activador dispuesto en una superficie de la carcasa para activar el mecanismo de impulsión. Un mecanismo de prevención de la activación está acoplado a la carcasa del inyector y/o mecanismo de prevención de la activación para impedir el accionamiento inadvertido del mecanismo activador.
MX2019010544A 2017-03-06 2018-03-06 Dispositivo de administracion de farmacos con caracteristica de prevencion de la activacion. MX2019010544A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762467602P 2017-03-06 2017-03-06
PCT/US2018/021126 WO2018165143A1 (en) 2017-03-06 2018-03-06 Drug delivery device with activation prevention feature

Publications (1)

Publication Number Publication Date
MX2019010544A true MX2019010544A (es) 2019-10-21

Family

ID=61750530

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019010544A MX2019010544A (es) 2017-03-06 2018-03-06 Dispositivo de administracion de farmacos con caracteristica de prevencion de la activacion.

Country Status (8)

Country Link
US (1) US11590277B2 (es)
EP (1) EP3592403B1 (es)
JP (2) JP2020508803A (es)
AU (1) AU2018231107B2 (es)
CA (1) CA3050927A1 (es)
ES (1) ES3051784T3 (es)
MX (1) MX2019010544A (es)
WO (1) WO2018165143A1 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1762259T3 (pl) 2005-09-12 2011-03-31 Unomedical As Urządzenie wprowadzające, przeznaczone do zestawu infuzyjnego, z pierwszą i drugą jednostką sprężynową
US10194938B2 (en) 2011-03-14 2019-02-05 UnoMedical, AS Inserter system with transport protection
JP6799001B2 (ja) 2015-03-10 2020-12-09 リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 注入装置
CN119950878A (zh) 2017-05-05 2025-05-09 里珍纳龙药品有限公司 自动注射器和相关使用方法
JP7465818B2 (ja) 2018-05-24 2024-04-11 ノバルティス アーゲー 自動薬物送達装置
EP3972672A4 (en) 2019-05-20 2023-06-21 Unomedical A/S Rotatable infusion device and methods thereof
USD955566S1 (en) * 2020-07-01 2022-06-21 Zealand Pharma A/S Medicament delivery device
US11311666B1 (en) 2021-02-18 2022-04-26 Fresenius Kabi Deutschland Gmbh Modular wearable medicament delivery device and method of use thereof
US11872369B1 (en) 2021-02-18 2024-01-16 Fresenius Kabi Deutschland Gmbh Wearable medicament delivery device with leakage and skin contact sensing and method of use thereof
US11464902B1 (en) 2021-02-18 2022-10-11 Fresenius Kabi Deutschland Gmbh Wearable medicament delivery device with compressible reservoir and method of use thereof
US11607505B1 (en) 2021-02-19 2023-03-21 Fresenius Kabi Deutschland Gmbh Wearable injector with sterility sensors
US11426523B1 (en) 2021-02-19 2022-08-30 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including a removable cartridge
US11344682B1 (en) 2021-02-19 2022-05-31 Fresenius Kabi Deutschland Gmbh Drug supply cartridge with visual use indicator and delivery devices that use the same
US11497847B1 (en) 2021-02-19 2022-11-15 Fresenius Kabi Deutschland Gmbh Wearable injector with adhesive substrate
US11413394B1 (en) 2021-02-19 2022-08-16 Fresenius Kabi Deutschland Gmbh Display for wearable drug delivery device
US11406755B1 (en) 2021-02-19 2022-08-09 Fresenius Kabi Deutschland Gmbh Sensing fluid flow irregularities in an on-body injector
US11633537B1 (en) 2021-02-19 2023-04-25 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including a pre-filled cartridge
US11529459B1 (en) 2021-04-30 2022-12-20 Fresenius Kabi Deutschland Gmbh Wearable injector with adhesive module
US11419976B1 (en) 2021-04-30 2022-08-23 Fresenius Kabi Deutschland Gmbh Wearable drug delivery device with pressurized fluid dispensing
US11351300B1 (en) 2021-04-30 2022-06-07 Fresenius Kabl Deutschland GmbH Drug dispensing system with replaceable drug supply cartridges
US11504470B1 (en) 2021-04-30 2022-11-22 Fresenius Kabi Deutschland Gmbh Deformable drug reservoir for wearable drug delivery device
US11717608B1 (en) 2021-05-03 2023-08-08 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including an adhesive pad
US11484646B1 (en) 2021-05-04 2022-11-01 Fresenius Kabi Deutschland Gmbh Sealing systems for a reservoir of an on-body injector
USD1007676S1 (en) 2021-11-16 2023-12-12 Regeneron Pharmaceuticals, Inc. Wearable autoinjector
USD1029241S1 (en) * 2022-05-06 2024-05-28 Sensile Medical Ag Medicine injector

Family Cites Families (179)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3927955A (en) 1971-08-23 1975-12-23 East West Medical Products Inc Medical cassette pump
US4703008A (en) 1983-12-13 1987-10-27 Kiren-Amgen, Inc. DNA sequences encoding erythropoietin
KR850004274A (ko) 1983-12-13 1985-07-11 원본미기재 에리트로포이에틴의 제조방법
NZ210501A (en) 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
KR100221066B1 (ko) 1989-10-13 1999-10-01 스튜어트 엘.왓트 에리트로포이에틴 유사체와 그를 포함하는 제약학적 조성물
US7217689B1 (en) 1989-10-13 2007-05-15 Amgen Inc. Glycosylation analogs of erythropoietin
US5856298A (en) 1989-10-13 1999-01-05 Amgen Inc. Erythropoietin isoforms
ZA946122B (en) 1993-08-17 1995-03-20 Amgen Inc Erythropoietin analogs
US6562596B1 (en) 1993-10-06 2003-05-13 Amgen Inc. Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods
US5773569A (en) 1993-11-19 1998-06-30 Affymax Technologies N.V. Compounds and peptides that bind to the erythropoietin receptor
US5830851A (en) 1993-11-19 1998-11-03 Affymax Technologies N.V. Methods of administering peptides that bind to the erythropoietin receptor
US5885574A (en) 1994-07-26 1999-03-23 Amgen Inc. Antibodies which activate an erythropoietin receptor
ES2251723T3 (es) 1994-08-12 2006-05-01 Immunomedics, Inc. Inmunoconjugados y anticuerpos humanizados especificos para linfoma de celulas b y celulas de leucemia.
US5686292A (en) 1995-06-02 1997-11-11 Genentech, Inc. Hepatocyte growth factor receptor antagonist antibodies and uses thereof
US5767078A (en) 1995-06-07 1998-06-16 Johnson; Dana L. Agonist peptide dimers
US5928194A (en) 1997-04-07 1999-07-27 Maget; Henri J. R. Self-contained liquid microdispenser
US6500150B1 (en) 1997-06-16 2002-12-31 Elan Pharma International Limited Pre-filled drug-delivery device and method of manufacture and assembly of same
IL133974A0 (en) 1997-07-14 2001-04-30 Bolder Biotechnology Inc Derivatives of growth hormone and related proteins
US6753165B1 (en) 1999-01-14 2004-06-22 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
US6391633B1 (en) 1997-07-23 2002-05-21 Roche Diagnostics Gmbh Production of erythropoietin by endogenous gene activation
US6030086A (en) 1998-03-02 2000-02-29 Becton, Dickinson And Company Flash tube reflector with arc guide
TW426531B (en) 1998-03-23 2001-03-21 Elan Corp Plc Improved drug delivery device
US6310078B1 (en) 1998-04-20 2001-10-30 Ortho-Mcneil Pharmaceutical, Inc. Substituted amino acids as erythropoietin mimetics
US20050181482A1 (en) 2004-02-12 2005-08-18 Meade Harry M. Method for the production of an erythropoietin analog-human IgG fusion proteins in transgenic mammal milk
ATE339507T1 (de) 1998-06-15 2006-10-15 Gtc Biotherapeutics Inc Erythropoietin-analog-menschliches serum-albumin fusionsprotein
ATE355303T1 (de) 1998-10-23 2006-03-15 Amgen Inc Methoden und zusammensetzungen zur prävention und behandlung der anämie
ATE348163T1 (de) 1998-10-23 2007-01-15 Amgen Inc Thrombopoietin substitute
CA2352532C (en) 1998-11-27 2014-10-14 Darwin Discovery Ltd. Compositions and methods for increasing bone mineralization
EP1006184A1 (en) 1998-12-03 2000-06-07 F. Hoffmann-La Roche Ag IGF-1 receptor interacting proteins (IIPs) genes coding therefor and uses thereof
JP2002544123A (ja) 1999-04-14 2002-12-24 スミスクライン・ビーチャム・コーポレイション エリトロポイエチン受容体抗体
US7297680B2 (en) 1999-04-15 2007-11-20 Crucell Holland B.V. Compositions of erythropoietin isoforms comprising Lewis-X structures and high sialic acid content
CZ299516B6 (cs) 1999-07-02 2008-08-20 F. Hoffmann-La Roche Ag Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem
CA2388617A1 (en) 1999-10-22 2001-05-03 Millennium Pharmaceuticals, Inc. Nucleic acid molecules derived from rat brain and programmed cell death models
US20050202538A1 (en) 1999-11-12 2005-09-15 Merck Patent Gmbh Fc-erythropoietin fusion protein with improved pharmacokinetics
AU2154401A (en) 1999-11-12 2001-05-30 Merck Patent Gmbh Erythropoietin forms with improved properties
US7223593B2 (en) 2000-01-21 2007-05-29 Biovex Limited Herpes virus strains for gene therapy
AUPQ599700A0 (en) 2000-03-03 2000-03-23 Super Internet Site System Pty Ltd On-line geographical directory
US6586398B1 (en) 2000-04-07 2003-07-01 Amgen, Inc. Chemically modified novel erythropoietin stimulating protein compositions and methods
DE60134003D1 (de) 2000-04-21 2008-06-26 Amgen Inc Verfahren und zusammensetzungen zur vermeidung und behandlung von anämie
US6756480B2 (en) 2000-04-27 2004-06-29 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
US7078376B1 (en) 2000-08-11 2006-07-18 Baxter Healthcare S.A. Therapeutic methods for treating subjects with a recombinant erythropoietin having high activity and reduced side effects
US20030191291A1 (en) 2000-09-08 2003-10-09 Kochendoerfer Gerd G. Synthetic erythropoiesis stimulating proteins
US7271689B1 (en) 2000-11-22 2007-09-18 Fonar Corporation Magnet structure
EP1345628B1 (en) 2000-12-20 2011-04-13 F. Hoffmann-La Roche AG Conjugates of erythropoietin (epo) with polyethylene glycol (peg)
ZA200305995B (en) 2001-01-05 2004-08-04 Pfizer Antibodies to insulin-like growth factor I receptor.
IL158261A0 (en) 2001-04-04 2004-05-12 Genodyssee New polynucleotides and polypeptides of the erythropoietin gene
HU229910B1 (hu) 2001-05-11 2014-12-29 Amgen Inc Thousand Oaks A TALL-1-hez kötõdõ peptidek és rokon molekulák
PH12012502439A1 (en) 2001-06-26 2013-06-17 Amgen Inc Antibodies to opgl
US6900292B2 (en) 2001-08-17 2005-05-31 Lee-Hwei K. Sun Fc fusion proteins of human erythropoietin with increased biological activities
CA2456648C (en) 2001-08-23 2011-08-16 Genmab A/S Human antibodies specific for interleukin 15 (il-15)
US7247304B2 (en) 2001-08-23 2007-07-24 Genmab A/S Methods of treating using anti-IL-15 antibodies
US6930086B2 (en) 2001-09-25 2005-08-16 Hoffmann-La Roche Inc. Diglycosylated erythropoietin
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7138370B2 (en) 2001-10-11 2006-11-21 Amgen Inc. Specific binding agents of human angiopoietin-2
US7521053B2 (en) 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents
WO2003055526A2 (en) 2001-12-21 2003-07-10 Maxygen Aps Erythropoietin conjugates
US7241444B2 (en) 2002-01-18 2007-07-10 Pierre Fabre Medicament Anti-IGF-IR antibodies and uses thereof
JP4606739B2 (ja) 2002-01-18 2011-01-05 ピエール、ファーブル、メディカマン 新規抗ｉｇｆ−ｉｒ抗体およびその使用
WO2003064664A1 (en) 2002-01-31 2003-08-07 Oxford Biomedica (Uk) Limited Physiologically regulated erythropoietin- exprressing vector for the treatment of anaemia
GB0202252D0 (en) 2002-01-31 2002-03-20 Oxford Biomedica Ltd Anemia
JP4109204B2 (ja) 2002-03-26 2008-07-02 レツク・フアーマシユーテイカルズ・デー・デー 所望エリスロポエチングリコアイソフォームプロフィールの製造方法
WO2003083118A1 (fr) 2002-03-29 2003-10-09 Kumiai Chemical Industry Co., Ltd. Genes codant l'acetolactase synthase
AU2003222069A1 (en) 2002-03-29 2003-10-20 Centocor, Inc. Mammalian cdr mimetibodies, compositions, methods and uses
CA2485365A1 (en) 2002-05-13 2003-11-20 Modigenetech Ltd. Ctp-extended erythropoietin
JP4563171B2 (ja) 2002-05-24 2010-10-13 シェーリング コーポレイション 中和ヒト抗ｉｇｆｒ抗体
US8034904B2 (en) 2002-06-14 2011-10-11 Immunogen Inc. Anti-IGF-I receptor antibody
US7538195B2 (en) 2002-06-14 2009-05-26 Immunogen Inc. Anti-IGF-I receptor antibody
JP2005536992A (ja) 2002-06-28 2005-12-08 セントカー・インコーポレーテツド 哺乳動物のｅｐｏ模倣ｃｈ１欠失ミメティボディ、組成物、方法および使用
AU2003280130B2 (en) 2002-06-28 2009-06-11 Centocor, Inc. Mammalian CH1 deleted mimetibodies, compositions, methods and uses
WO2004009627A1 (en) 2002-07-19 2004-01-29 Cangene Corporation Pegylated erythropoietic compounds
TW200413406A (en) 2002-08-26 2004-08-01 Kirin Brewery Peptides and drugs containing the same
EP2277543B1 (en) 2002-09-06 2015-12-16 Amgen, Inc Therapeutic anti-IL-1R1 monoclonal antibody
MXPA05002591A (es) 2002-09-11 2005-09-20 Fresenius Kabi Gmbh Derivados de almidon de hidroxialquilo.
US6919426B2 (en) 2002-09-19 2005-07-19 Amgen Inc. Peptides and related molecules that modulate nerve growth factor activity
US7396913B2 (en) 2002-10-14 2008-07-08 Abbott Laboratories Erythropoietin receptor binding antibodies
TWI320716B (en) 2002-10-14 2010-02-21 Abbott Lab Erythropoietin receptor binding antibodies
US20040071694A1 (en) 2002-10-14 2004-04-15 Devries Peter J. Erythropoietin receptor binding antibodies
US7335743B2 (en) 2002-10-16 2008-02-26 Amgen Inc. Human anti-IFN-γ neutralizing antibodies as selective IFN-γ pathway inhibitors
US20040091961A1 (en) 2002-11-08 2004-05-13 Evans Glen A. Enhanced variants of erythropoietin and methods of use
PL383616A1 (pl) 2002-12-20 2008-04-14 Amgen Inc. Środki wiążące inhibitujące miostatynę
BRPI0408317A (pt) 2003-03-14 2006-03-07 Pharmacia Corp anticorpos do receptor de igf-i para o tratamento de cáncer
WO2004087756A2 (en) 2003-04-02 2004-10-14 F. Hoffmann-La Roche Ag Antibodies against insulin-like growth factor i receptor and uses thereof
US7220410B2 (en) 2003-04-18 2007-05-22 Galaxy Biotech, Llc Monoclonal antibodies to hepatocyte growth factor
ES2527871T3 (es) 2003-05-01 2015-02-02 Imclone Llc Anticuerpos completamente humanos dirigidos contra el receptor del factor de crecimiento 1 similar a la insulina humana
TWI353991B (en) 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
UA88146C2 (ru) 2003-05-12 2009-09-25 Афимакс, Инк. Новые пептиды, которые связываются с рецептором эритропоэтина
PL1625156T3 (pl) 2003-05-12 2013-03-29 Affymax Inc Peptydy wiążące się do receptora erytropoetyny
WO2004101600A2 (en) 2003-05-12 2004-11-25 Affymax, Inc. Novel poly(ethylene glycol) modified compounds and uses thereof
US7074755B2 (en) 2003-05-17 2006-07-11 Centocor, Inc. Erythropoietin conjugate compounds with extended half-lives
JP2007537986A (ja) 2003-05-30 2007-12-27 セントカー・インコーポレーテツド トランスグルタミナーゼを用いる新規なエリトロポエチン複合体の形成
WO2005001136A1 (en) 2003-06-04 2005-01-06 Irm Llc Methods and compositions for modulating erythropoietin expression
WO2004110527A1 (de) 2003-06-12 2004-12-23 Disetronic Licensing Ag Insertionsvorrichtung für infusionssets
US7579157B2 (en) 2003-07-10 2009-08-25 Hoffmann-La Roche Inc. Antibody selection method against IGF-IR
ES2392954T3 (es) 2003-07-15 2012-12-17 Amgen Inc. Anticuerpos neutralizantes anti-NGF humanos como inhibidores selectivos de la ruta de NGF
CN103755807A (zh) 2003-07-18 2014-04-30 安姆根有限公司 肝细胞生长因子的特异性结合物
US20050019914A1 (en) 2003-07-24 2005-01-27 Aventis Pharma Deutschland Gmbh Perfusion process for producing erythropoietin
GB0317511D0 (en) 2003-07-25 2003-08-27 Biovex Ltd Viral vectors
US20070275871A1 (en) 2003-08-28 2007-11-29 Biorexis Technology, Inc. Epo Mimetic Peptides and Fusion Proteins
BRPI0409650A (pt) 2003-09-09 2006-04-25 Warren Pharmaceuticals Inc métodos para regular o nìvel hematócrito e humanos, produtos de eritropoietina artificial, métodos para preparar um produto de eritropoietina e pra tratar anemia em pacientes em risco de dano no tecido, e, composição farmacêutica
IL157984A (en) 2003-09-17 2015-02-26 Dali Medical Devices Ltd Automatic needle
UA89481C2 (uk) 2003-09-30 2010-02-10 Центокор, Инк. Еритропоетинові міметичні шарнірно-серцевинні міметитіла людини, композиції, способи та застосування
JP4767857B2 (ja) 2003-09-30 2011-09-07 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ベンゾイミダゾール化合物
UA93653C2 (ru) 2003-11-07 2011-03-10 Иммунекс Корпорейшн Выделенное антитело, kotopoe специфически связывается c человеческим рецептором il-4 (il-4r)
PE20050928A1 (es) 2003-11-21 2005-11-08 Schering Corp Combinaciones terapeuticas de anticuerpo anti-igfr1
EP1694347B1 (en) 2003-11-24 2013-11-20 BioGeneriX AG Glycopegylated erythropoietin
US8633157B2 (en) 2003-11-24 2014-01-21 Novo Nordisk A/S Glycopegylated erythropoietin
WO2005058967A2 (en) 2003-12-16 2005-06-30 Pierre Fabre Medicament Novel anti-insulin/igf-i hybrid receptor or anti-insulin/igf-i hybrid receptor and igf-ir antibodies and uses thereof
EP1548031A1 (en) 2003-12-22 2005-06-29 Dubai Genetics FZ-LLC Nature-identical erythropoietin
JP2008500275A (ja) 2003-12-31 2008-01-10 セントカー・インコーポレーテツド Ｎ末端の遊離チオールを有する新規な組み換えタンパク質
CA2551916C (en) 2003-12-31 2014-04-29 Merck Patent Gesellschaft Mit Beschraenkter Haftung Fc-erythropoietin fusion protein with improved pharmacokinetics
US7423139B2 (en) 2004-01-20 2008-09-09 Insight Biopharmaceuticals Ltd. High level expression of recombinant human erythropoietin having a modified 5′-UTR
WO2005070451A1 (en) 2004-01-22 2005-08-04 Zafena Aktiebolag Pharmaceutical composition comprising non-glycosylated erythropoietin
WO2005084711A1 (en) 2004-03-02 2005-09-15 Chengdu Institute Of Biological Products A pegylated recombinant erythropoietin that has in vivo activity
AR048918A1 (es) 2004-03-11 2006-06-14 Fresenius Kabi De Gmbh Conjugados de almidon de hidroxietilo y eritropoyetina
AU2005229009A1 (en) 2004-03-23 2005-10-13 Amgen, Inc. Monoclonal antibodies specific for human OX40L (CD 134L)
US20050227289A1 (en) 2004-04-09 2005-10-13 Reilly Edward B Antibodies to erythropoietin receptor and uses thereof
AU2005235794A1 (en) 2004-04-23 2005-11-03 Cambridge Antibody Technology Limited Erythropoietin protein variants
PL1781697T3 (pl) 2004-07-07 2009-10-30 H Lundbeck As Nowa karbamylowana EPO i sposób jej wytwarzania
FR2873699B1 (fr) 2004-07-29 2009-08-21 Pierre Fabre Medicament Sa Nouveaux anticorps anti igf ir rt leurs utilisations
WO2006029094A2 (en) 2004-09-02 2006-03-16 Xencor, Inc. Erythropoietin derivatives with altered immunogenicity
WO2006050959A2 (en) 2004-11-10 2006-05-18 Aplagen Gmbh Molecules which promote hematopoiesis
MY146381A (en) 2004-12-22 2012-08-15 Amgen Inc Compositions and methods relating relating to anti-igf-1 receptor antibodies
US7906625B2 (en) 2005-01-24 2011-03-15 Amgen Inc. Humanized anti-amyloid antibody
DK2058020T3 (da) 2005-02-01 2013-01-07 Intelliject Inc Indretning til indgivelse af lægemiddel
US7731686B2 (en) 2005-02-01 2010-06-08 Intelliject, Inc. Devices, systems and methods for medicament delivery
US7592429B2 (en) 2005-05-03 2009-09-22 Ucb Sa Sclerostin-binding antibody
CA2680945C (en) 2005-06-17 2014-03-18 Imclone Systems Incorporated Anti-pdgfralpha antibodies
WO2007000328A1 (en) 2005-06-27 2007-01-04 Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa Antibodies that bind to an epitope on insulin-like growth factor 1 receptor and uses thereof
KR20130023356A (ko) 2005-07-18 2013-03-07 메다렉스, 인코포레이티드 인간 항-ｂ7ｒｐ1 중화 항체
FR2888850B1 (fr) 2005-07-22 2013-01-11 Pf Medicament Nouveaux anticorps anti-igf-ir et leurs applications
PE20071101A1 (es) 2005-08-31 2007-12-21 Amgen Inc Polipeptidos y anticuerpos
GB0603683D0 (en) 2006-02-23 2006-04-05 Novartis Ag Organic compounds
TWI395754B (zh) 2006-04-24 2013-05-11 Amgen Inc 人類化之ｃ-ｋｉｔ抗體
RU2008150314A (ru) 2006-05-19 2010-06-27 Гликофи, Инк. (Us) Композиции эритропоэтина
CL2007002567A1 (es) 2006-09-08 2008-02-01 Amgen Inc Proteinas aisladas de enlace a activina a humana.
WO2008133647A2 (en) 2006-11-07 2008-11-06 Merck & Co., Inc. Antagonists of pcsk9
EP2083860A4 (en) 2006-11-07 2010-05-26 Merck Sharp & Dohme PCSK9 ANTAGONISTS
EP2083861A4 (en) 2006-11-07 2010-11-24 Merck Sharp & Dohme ANTAGONISTS OF PCSK9
WO2008057457A2 (en) 2006-11-07 2008-05-15 Merck & Co., Inc. Antagonists of pcsk9
PH12013500355A1 (en) 2006-12-14 2021-08-09 Schering Corp Engineered anti-tslp antibody
WO2008125623A2 (en) 2007-04-13 2008-10-23 Novartis Ag Molecules and methods for modulating proprotein convertase subtilisin/kexin type 9 (pcsk9)
KR20100034015A (ko) 2007-06-20 2010-03-31 아이알엠 엘엘씨 알레르기 질환 치료를 위한 방법 및 조성물
US7982016B2 (en) 2007-09-10 2011-07-19 Amgen Inc. Antigen binding proteins capable of binding thymic stromal lymphopoietin
CA2703712A1 (en) 2007-10-26 2009-04-30 Joseph A. Hedrick Anti-pcsk9 and methods for treating lipid and cholesterol disorders
AR070316A1 (es) 2008-02-07 2010-03-31 Merck & Co Inc Antagonistas de pcsk9 (proproteina subtilisina-kexina tipo 9)
AR070315A1 (es) 2008-02-07 2010-03-31 Merck & Co Inc Anticuerpos 1b20 antagonistas de pcsk9
JP5731829B2 (ja) * 2008-03-10 2015-06-10 アンタレス・ファーマ・インコーポレーテッド 注射器安全装置
TWI445716B (zh) 2008-09-12 2014-07-21 Rinat Neuroscience Corp Ｐｃｓｋ９拮抗劑類
JO3672B1 (ar) 2008-12-15 2020-08-27 Regeneron Pharma أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9).
JO3382B1 (ar) 2008-12-23 2019-03-13 Amgen Inc أجسام مضادة ترتبط مع مستقبل cgrp بشري
EP2480576A4 (en) 2009-09-25 2013-04-10 Merck Sharp & Dohme PCSK9 ANTAGONISTS
CN104474606B (zh) * 2009-10-13 2017-04-26 瓦莱里塔斯公司 流体输送装置
AU2010313324A1 (en) 2009-10-30 2012-04-12 Merck Sharp & Dohme Corp. AX213 and AX132 PCSK9 antagonists and variants
WO2011053759A1 (en) 2009-10-30 2011-05-05 Merck Sharp & Dohme Corp. Ax1 and ax189 pcsk9 antagonists and variants
AR079336A1 (es) 2009-12-11 2012-01-18 Irm Llc Antagonistas de la pro-proteina convertasa-subtilisina/quexina tipo 9 (pcsk9)
EP2545079A2 (en) 2010-03-11 2013-01-16 Rinat Neuroscience Corporation ANTIBODIES WITH pH DEPENDENT ANTIGEN BINDING
WO2012032411A2 (en) 2010-09-07 2012-03-15 Tecpharma Licensing Ag Automatic injection device
WO2012054438A1 (en) 2010-10-22 2012-04-26 Schering Corporation Anti-pcsk9
TW201307391A (zh) 2010-12-22 2013-02-16 Genentech Inc 抗－ｐｃｓｋ９抗體及其使用方法
PH12013501576A1 (en) 2011-01-28 2013-09-30 Sanofi Biotechnology Pharmaceutical compositions comprising human antibodies to pcsk9
EP2673031B1 (en) * 2011-02-09 2020-07-15 Becton, Dickinson and Company Medical infusion device comprising a self-contained torsion spring inserter
MX2013009258A (es) 2011-02-11 2013-10-17 Novartis Ag Antagonistas de pcsk9.
JP6210558B2 (ja) * 2011-07-25 2017-10-11 プレシフレックス エスアー 流体投与装置
DK2782630T3 (da) * 2011-11-22 2020-01-13 Becton Dickinson Co Medikamentleveringssystem med en forsinkelsesmekanisme
EP2827923B1 (en) * 2012-03-19 2018-12-26 Steadymed Ltd. Fluid-connection mechanism for patch-pumps
JP6224075B2 (ja) * 2012-04-13 2017-11-01 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ 不用意な起動を防ぐ安全機能を備えた注入装置
US9333292B2 (en) * 2012-06-26 2016-05-10 Medtronic Minimed, Inc. Mechanically actuated fluid infusion device
EP2935311B1 (en) 2012-12-20 2021-03-31 Amgen Inc. Apj receptor agonists and uses thereof
AU2013370281B2 (en) 2012-12-27 2017-09-07 Kaleo, Inc. Devices, systems and methods for locating and interacting with medicament delivery systems
US9486297B2 (en) 2013-01-25 2016-11-08 M. Wade Clayton Light for oral anesthesia injection syringe
US20140274874A1 (en) 2013-03-14 2014-09-18 Amgen Inc. Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods
US10189890B2 (en) 2013-03-14 2019-01-29 Amgen Inc. Variants of tissue inhibitor of metalloproteinase type three (TIMP-3), compositions and methods
US9186456B2 (en) * 2013-04-30 2015-11-17 Avent, Inc. Flow selector device alignment system
WO2014197317A1 (en) 2013-06-03 2014-12-11 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using multiple reservoirs
EP3010568B1 (en) * 2013-06-18 2019-02-27 Enable Injections, Inc. Vial transfer and injection apparatus
EP2944340A1 (en) 2014-05-12 2015-11-18 Sanofi Activating mechanism for a medicament delivery device and medicament delivery device
CN107278158A (zh) 2014-09-29 2017-10-20 尤尼特拉克特注射器控股有限公司 用于药物输送泵的刚性针插入机构
CN107614034B (zh) * 2015-04-24 2024-04-26 贝克顿·迪金森公司 用于导管插入装置的按钮安全帽
US10080837B2 (en) * 2015-07-07 2018-09-25 Flextronics Ap, Llc. Sterile patch pump

Also Published As

Publication number Publication date
EP3592403A1 (en) 2020-01-15
AU2018231107A1 (en) 2019-08-01
JP2020508803A (ja) 2020-03-26
CA3050927A1 (en) 2018-09-13
JP2022163158A (ja) 2022-10-25
WO2018165143A1 (en) 2018-09-13
AU2018231107B2 (en) 2023-04-20
US11590277B2 (en) 2023-02-28
EP3592403B1 (en) 2025-08-20
US20190381238A1 (en) 2019-12-19
ES3051784T3 (en) 2025-12-30

Similar Documents

Publication Publication Date Title
MX2019010544A (es) Dispositivo de administracion de farmacos con caracteristica de prevencion de la activacion.
CL2023003062A1 (es) Dispositivos y métodos para administración exacta de dosis
CY1122354T1 (el) Αυτοματος εγχυτηρας μiας χρησεως
MX2019010543A (es) Insercion de agujas por sobrepresion.
WO2019032482A3 (en) HYDRAULIC-PNEUMATIC PRESSURE CHAMBER DELIVERY SYSTEM
MX2021004219A (es) Dispositivo de administracion de farmacos con mecanismo de amortiguacion.
MX2022003703A (es) Dispositivo de administracion de farmacos.
AR088375A1 (es) Auto-inyector
MX2021010055A (es) Autoinyector con indicador de audio.
MX2021011213A (es) Mecanismo de insercion con desvio rotacional para una bomba de administracion de farmacos.
MX372859B (es) Aparatos y métodos para inyección ocular.
AR085254A1 (es) Dispositivo de inyeccion
AR037305A1 (es) Autoinyector neumatico energizado
MX2020009431A (es) Dispositivos para inyectar medicamentos y metodos de uso.
MX2022002580A (es) Dispositivo de inyeccion activable para administracion de farmacos.
MX2021010179A (es) Autoinyector con cubierta de aguja.
AR116607A1 (es) Dispositivo de administración de fármacos con indicador de dosis
BR112019002267A2 (pt) sistema de injeção de implante/medicamento baseado em alojamento de segurança
WO2019092469A8 (en) Handheld drug delivery device
EP4534125A3 (en) Safety device with collapsible housing and trigger activation
EP4434562A3 (en) Medicament delivery device and actuation mechanism for a drug delivery device
MX2024013000A (es) Mecanismo de activacion para dispositivo de suministro de farmacos
MX2017012591A (es) Dispositivos para suministro dirigido de implantes terapeuticos.
MX2022012850A (es) Dispositivos de administracion de sustancias terapeuticas.
CL2021002030A1 (es) Dispositivo de administración para la administración de un fluido