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DE60134003D1 - Verfahren und zusammensetzungen zur vermeidung und behandlung von anämie - Google Patents

Verfahren und zusammensetzungen zur vermeidung und behandlung von anämie

Info

Publication number
DE60134003D1
DE60134003D1 DE60134003T DE60134003T DE60134003D1 DE 60134003 D1 DE60134003 D1 DE 60134003D1 DE 60134003 T DE60134003 T DE 60134003T DE 60134003 T DE60134003 T DE 60134003T DE 60134003 D1 DE60134003 D1 DE 60134003D1
Authority
DE
Germany
Prior art keywords
compositions
analogs
erythropoietin
analog
hyperglycosylated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60134003T
Other languages
English (en)
Inventor
Joan C Egrie
Steven G Elliott
Jeffrey K Browne
Karen C Sitney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of DE60134003D1 publication Critical patent/DE60134003D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60134003T 2000-04-21 2001-04-19 Verfahren und zusammensetzungen zur vermeidung und behandlung von anämie Expired - Lifetime DE60134003D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55900100A 2000-04-21 2000-04-21
PCT/US2001/012836 WO2001081405A2 (en) 2000-04-21 2001-04-19 Methods and compositions for the prevention and treatment of anemia

Publications (1)

Publication Number Publication Date
DE60134003D1 true DE60134003D1 (de) 2008-06-26

Family

ID=24231877

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60134003T Expired - Lifetime DE60134003D1 (de) 2000-04-21 2001-04-19 Verfahren und zusammensetzungen zur vermeidung und behandlung von anämie

Country Status (13)

Country Link
EP (4) EP2292650A1 (de)
JP (1) JP5022551B2 (de)
AT (1) ATE395357T1 (de)
AU (2) AU5551601A (de)
CA (2) CA2406807C (de)
CY (1) CY1108154T1 (de)
DE (1) DE60134003D1 (de)
DK (1) DK1274728T3 (de)
ES (1) ES2306711T3 (de)
MX (1) MXPA02010333A (de)
PT (1) PT1274728E (de)
SI (1) SI1274728T1 (de)
WO (1) WO2001081405A2 (de)

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EP1605057A3 (de) * 2004-06-09 2006-11-02 Klaus Heyne Verfahren zur Herstellung hyperglykosylierter Proteine
US9988427B2 (en) 2005-05-13 2018-06-05 Charite Universitaetsmedizen-Berlin Erythropoietin variants
KR20080026113A (ko) * 2005-05-24 2008-03-24 아베스타 겐그레인 테크놀로지스 피브이티 리미티드 적혈구생성 자극 단백질의 생산을 위한 재조합 방법
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US7625564B2 (en) 2006-01-27 2009-12-01 Novagen Holding Corporation Recombinant human EPO-Fc fusion proteins with prolonged half-life and enhanced erythropoietic activity in vivo
AU2007275638B2 (en) 2006-07-21 2014-01-16 Amgen Inc. Method of detecting and/ or measuring hepcidin in a sample
EP2081956B1 (de) 2006-11-13 2013-03-20 Charité - Universitätsmedizin Berlin Zellkulturverfahren und behandlungsverfahren mit einer vepo-protein-variante
KR101248252B1 (ko) 2006-11-28 2013-03-27 한올바이오파마주식회사 변형된 에리스로포이에틴 폴리펩티드와 이의 치료용 용도
US8067548B2 (en) 2007-07-26 2011-11-29 Novagen Holding Corporation Fusion proteins having mutated immunoglobulin hinge region
CA2701032C (en) 2007-09-27 2021-01-26 Amgen Inc. Pharmaceutical formulations
ES2962777T3 (es) 2007-11-15 2024-03-21 Amgen Inc Formulación acuosa de anticuerpos estabilizada por antioxidantes para la administración parenteral
CA2711826C (en) 2008-01-25 2018-02-27 Amgen Inc. Ferroportin antibodies and methods of use
US9315577B2 (en) 2008-05-01 2016-04-19 Amgen Inc. Anti-hepcidin antibodies and methods of use
EP2161031A1 (de) 2008-09-05 2010-03-10 SuppreMol GmbH Fc-gamma-Rezeptor zur Behandlung von B-Zellen-vermittelter multipler Sklerose
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Also Published As

Publication number Publication date
EP2292650A1 (de) 2011-03-09
PT1274728E (pt) 2008-06-20
ATE395357T1 (de) 2008-05-15
CA2690018A1 (en) 2001-11-01
JP5022551B2 (ja) 2012-09-12
EP1274728A2 (de) 2003-01-15
ES2306711T3 (es) 2008-11-16
MXPA02010333A (es) 2003-04-25
SI1274728T1 (sl) 2008-08-31
EP1274728B1 (de) 2008-05-14
CA2406807C (en) 2010-04-06
EP2292651A1 (de) 2011-03-09
CY1108154T1 (el) 2014-02-12
WO2001081405A3 (en) 2002-05-16
AU2001255516B2 (en) 2007-01-18
EP1961425A3 (de) 2008-11-26
WO2001081405A2 (en) 2001-11-01
EP1961425B1 (de) 2017-07-19
EP1961425A2 (de) 2008-08-27
AU5551601A (en) 2001-11-07
CA2406807A1 (en) 2001-11-01
JP2003530874A (ja) 2003-10-21
DK1274728T3 (da) 2008-09-01

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