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MX2019005688A - Glicosidos de esteviol de alta pureza. - Google Patents

Glicosidos de esteviol de alta pureza.

Info

Publication number
MX2019005688A
MX2019005688A MX2019005688A MX2019005688A MX2019005688A MX 2019005688 A MX2019005688 A MX 2019005688A MX 2019005688 A MX2019005688 A MX 2019005688A MX 2019005688 A MX2019005688 A MX 2019005688A MX 2019005688 A MX2019005688 A MX 2019005688A
Authority
MX
Mexico
Prior art keywords
steviol glycosides
methods
reb
highly purified
rebaudiosides
Prior art date
Application number
MX2019005688A
Other languages
English (en)
Other versions
MX395693B (es
Inventor
Prakash Indra
Bunders Cynthia
Cyrille Jarrin
Markosyan Avetik
Soni Pankaj
Badie Aurélien
Ter Halle Robert
Original Assignee
Purecircle Sdn Bhd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51985807&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2019005688(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Purecircle Sdn Bhd filed Critical Purecircle Sdn Bhd
Publication of MX2019005688A publication Critical patent/MX2019005688A/es
Publication of MX395693B publication Critical patent/MX395693B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A23L2/60—Sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/302—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by natural substances obtained from animals or plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Agronomy & Crop Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Seasonings (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

Se describen métodos para preparar glicósidos de esteviol altamente purificados, particularmente rebaudiósidos A, D y M. Los métodos incluyen la utilización de microorganismos recombinantes para convertir varias composiciones de partida a los glicósidos de esteviol objetivo. Además, se describen glicósidos de esteviol novedosos reb D2 y reb M2, así como métodos para preparar los mismos. Los rebaudiósidos altamente purificados con útiles como edulcorante no calórico en composiciones comestibles y masticables tales como cualquiera de bebidas, confiterías, productos de panadería, galletitas y gomas de mascar.
MX2019005688A 2013-05-28 2014-05-28 Glicosidos de esteviol de alta pureza. MX395693B (es)

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US201361827922P 2013-05-28 2013-05-28
US201361843544P 2013-07-08 2013-07-08
US201361861528P 2013-08-02 2013-08-02
US201361881166P 2013-09-23 2013-09-23
US201361885084P 2013-10-01 2013-10-01
US201361904751P 2013-11-15 2013-11-15
US201361913482P 2013-12-09 2013-12-09
US201361921635P 2013-12-30 2013-12-30
US201461925329P 2014-01-09 2014-01-09
US201461939855P 2014-02-14 2014-02-14
US14/287,837 US9752174B2 (en) 2013-05-28 2014-05-27 High-purity steviol glycosides
PCT/US2014/039666 WO2014193888A1 (en) 2013-05-28 2014-05-28 High-purity steviol glycosides

Publications (2)

Publication Number Publication Date
MX2019005688A true MX2019005688A (es) 2019-09-05
MX395693B MX395693B (es) 2025-03-25

Family

ID=51985807

Family Applications (4)

Application Number Title Priority Date Filing Date
MX2019005688A MX395693B (es) 2013-05-28 2014-05-28 Glicosidos de esteviol de alta pureza.
MX2015016362A MX365044B (es) 2013-05-28 2014-05-28 Glicosidos de esteviol de alta pureza.
MX2015016096A MX384819B (es) 2013-05-28 2014-05-28 Glucosidos de esteviol de alta pureza.
MX2021008960A MX2021008960A (es) 2013-05-28 2015-11-23 Glicosidos de esteviol de alta pureza.

Family Applications After (3)

Application Number Title Priority Date Filing Date
MX2015016362A MX365044B (es) 2013-05-28 2014-05-28 Glicosidos de esteviol de alta pureza.
MX2015016096A MX384819B (es) 2013-05-28 2014-05-28 Glucosidos de esteviol de alta pureza.
MX2021008960A MX2021008960A (es) 2013-05-28 2015-11-23 Glicosidos de esteviol de alta pureza.

Country Status (7)

Country Link
US (5) US9752174B2 (es)
EP (2) EP3004128A4 (es)
CN (4) CN112538512A (es)
BR (2) BR112015029684B1 (es)
CA (2) CA2913252C (es)
MX (4) MX395693B (es)
WO (2) WO2014193934A1 (es)

Families Citing this family (117)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9107436B2 (en) 2011-02-17 2015-08-18 Purecircle Sdn Bhd Glucosylated steviol glycoside as a flavor modifier
US10696706B2 (en) 2010-03-12 2020-06-30 Purecircle Usa Inc. Methods of preparing steviol glycosides and uses of the same
US20150344512A1 (en) 2011-12-19 2015-12-03 Purecircle Usa Inc. Methods of purifying steviol glycosides and uses of the same
US11690391B2 (en) 2011-02-17 2023-07-04 Purecircle Sdn Bhd Glucosylated steviol glycoside as a flavor modifier
US9771434B2 (en) 2011-06-23 2017-09-26 Purecircle Sdn Bhd Products from stevia rebaudiana
EP3345490B1 (en) 2011-12-19 2023-11-08 The Coca-Cola Company Beverage comprising rebaudioside x
EP2826861B1 (en) 2012-03-16 2020-04-29 Suntory Holdings Limited Steviol glycosyltransferase and gene encoding same
ES2820518T3 (es) 2012-03-27 2021-04-21 Suntory Holdings Ltd Método para producir glucósido de esteviol
CN110358795B (zh) 2012-05-22 2024-12-03 谱赛科有限责任公司 高纯度的甜菊醇糖苷
US9752174B2 (en) 2013-05-28 2017-09-05 Purecircle Sdn Bhd High-purity steviol glycosides
TW201402599A (zh) 2012-05-30 2014-01-16 Suntory Holdings Ltd 甜菊糖苷糖苷轉化酵素及編碼該酵素之基因
PL3714699T3 (pl) 2013-06-07 2025-04-28 Purecircle Usa Inc. EKSTRAKT Z STEWII ZAWIERAJĄCY WYBRANE GLIKOZYDY STEWIOLOWE JAKO MODYFIKATOR PROFILU SMAKOWEGO, SŁONEGO i SŁODKIEGO
US10952458B2 (en) 2013-06-07 2021-03-23 Purecircle Usa Inc Stevia extract containing selected steviol glycosides as flavor, salty and sweetness profile modifier
CN103397064B (zh) * 2013-08-14 2015-04-15 苏州汉酶生物技术有限公司 一种酶法制备瑞鲍迪甙m的方法
US9522929B2 (en) * 2014-05-05 2016-12-20 Conagen Inc. Non-caloric sweetener
WO2016028899A1 (en) * 2014-08-19 2016-02-25 The Coca-Cola Company Methods for preparing rebaudioside i and uses
BR112017004238A2 (pt) 2014-09-02 2017-12-12 Purecircle Usa Inc extratos de estévia enriquecidos em rebaudiosídeo d, e, n e/ou o e processo para a preparação dos mesmos
WO2017035527A1 (en) * 2015-08-27 2017-03-02 Purecircle Sdn Bhd Stevia extracts
EP3193636B1 (en) * 2014-09-19 2022-07-06 PureCircle SDN BHD High-purity steviol glycosides
EP3202269B1 (en) 2014-09-30 2020-04-08 Suntory Holdings Limited Carbonated beverage, syrup to be used for preparing carbonated beverage, method for manufacturing carbonated beverage, and method for suppressing generation of bubbles in carbonated beverage
CN106714578B (zh) * 2014-10-03 2020-07-28 康纳根有限公司 无热量甜味剂及合成方法
EP3215629B1 (en) 2014-11-05 2024-08-07 Manus Bio Inc. Microbial production of steviol glycosides
WO2016100689A1 (en) 2014-12-17 2016-06-23 Cargill, Incorporated Steviol glycoside compounds, compositions for oral ingestion or use, and method for enhancing steviol glycoside solubility
US10604743B2 (en) 2015-03-16 2020-03-31 Dsm Ip Assets B.V. UDP-glycosyltransferases
WO2016151046A1 (en) * 2015-03-23 2016-09-29 Dsm Ip Assets B.V. Udp-glycosyltransferases from solanum lycopersicum
BR112017021066B1 (pt) 2015-04-03 2022-02-08 Dsm Ip Assets B.V. Glicosídeos de esteviol, método para a produção de um glicosídeo de esteviol, composição, usos relacionados, gênero alimentício, alimento para animais e bebida
US10752928B2 (en) 2015-04-14 2020-08-25 Conagen Inc. Production of non-caloric sweeteners using engineered whole-cell catalysts
AU2016271628B2 (en) 2015-05-29 2020-01-30 Cargill, Incorporated Fermentation methods for producing steviol glycosides using high pH and compositions obtained therefrom
EP4063513A1 (en) 2015-05-29 2022-09-28 Cargill, Incorporated Heat treatment to produce glycosides
CN107614677A (zh) 2015-05-29 2018-01-19 嘉吉公司 用于使用多阶段进料生产甜菊醇糖苷的发酵方法
CA2991662A1 (en) * 2015-07-10 2017-01-19 Dsm Ip Assets B.V. Steviol glycoside composition
AU2016301190A1 (en) 2015-08-06 2018-02-15 Cargill, Incorporated Fermentation methods for producing steviol glycosides
US20190203244A1 (en) * 2015-08-20 2019-07-04 Pepsico, Inc. Preparation of rebaudioside m in a single reaction vessel
ES2970118T3 (es) 2015-10-26 2024-05-27 Purecircle Usa Inc Composiciones de glicósido de esteviol
US11653686B2 (en) 2015-12-15 2023-05-23 Purecircle Usa Inc. Steviol glycoside compositions
JP6109353B1 (ja) 2016-01-05 2017-04-05 サントリー食品インターナショナル株式会社 飲料、飲料の製造方法、及び飲料の泡立ちを抑制する方法
WO2017120480A1 (en) 2016-01-07 2017-07-13 Purecircle Usa Inc. Highly soluble steviol glycosides
JP6257863B1 (ja) * 2016-03-31 2018-01-10 サントリーホールディングス株式会社 ステビア含有飲料
CN109152379B (zh) 2016-03-31 2023-10-27 三得利控股株式会社 含有茶聚合多酚和RebD及/或RebM的饮料
WO2017189994A1 (en) * 2016-04-29 2017-11-02 Pepsico, Inc. Novel steviol glycosides blends
CN105919016A (zh) * 2016-04-29 2016-09-07 清流县冠裕食品有限公司 罐头食品甜味剂配方
EP3455233A4 (en) * 2016-05-10 2020-03-11 The Coca-Cola Company METHOD FOR FREEZING DRYING COMPOSITIONS WITH REBAUDIOSIDE M AND REBAUDIOSIDE D
WO2017198682A1 (en) 2016-05-16 2017-11-23 Evolva Sa Production of steviol glycosides in recombinant hosts
AU2017284104B2 (en) 2016-06-15 2020-06-25 Codexis, Inc. Engineered beta-glucosidases and glucosylation methods
US10494397B2 (en) * 2016-07-15 2019-12-03 Pepsico, Inc. Rebaudioside analogs
WO2018029272A1 (en) * 2016-08-09 2018-02-15 Dsm Ip Assets B.V. Crystallization of steviol glycosides
ES2906310T3 (es) 2016-08-12 2022-04-18 Amyris Inc Glicosiltransferasa dependiente de UDP para la producción de alta eficiencia de rebaudiósidos
US10085472B2 (en) * 2016-08-29 2018-10-02 Pepsico, Inc. Compositions comprising rebaudioside J
WO2018066895A1 (ko) * 2016-10-07 2018-04-12 씨제이제일제당(주) 알룰로스를 이용한, 알코올성 음료의 알코올감의 개선 방법
EP3525598B1 (en) * 2016-10-14 2023-11-29 Conagen Inc. Biosynthetic production of steviol glycosides and processes therefor
US11359222B2 (en) 2016-10-21 2022-06-14 Pepsico, Inc. Enzymatic method for preparing Rebaudioside j
JP6972123B2 (ja) * 2016-10-21 2021-11-24 ペプシコ・インク 酵素法を使用するレバウディオサイドｎを調製するための方法
WO2018072203A1 (zh) * 2016-10-21 2018-04-26 苏州汉酶生物技术有限公司 一种酶法制备瑞鲍迪甙c的方法
MX2019005570A (es) 2016-11-14 2019-10-15 Purecircle Usa Inc Moleculas derivadas de estevia, metodos para obtener dichas moleculas y uso de las mismas.
JP7228511B2 (ja) * 2016-11-16 2023-02-24 ザ コカ・コーラ カンパニー ミラクルフルーツによるステビア甘味飲料の味覚改善
CN106834389B (zh) * 2016-12-13 2020-03-17 南京工业大学 一种重组菌催化莱鲍迪甙a制备莱鲍迪甙m2的方法
CN106754595B (zh) * 2016-12-13 2019-10-22 南京工业大学 一株重组菌及其在催化莱鲍迪甙a生成莱鲍迪甙d中的应用
WO2018112189A1 (en) 2016-12-14 2018-06-21 The Coca-Cola Company Preparing novel steviol glycosides by bioconversion
IL268121B2 (en) 2017-02-03 2024-01-01 Codexis Inc Engineered glycosyltransferases and steviol glycoside glucosylation methods
CN108441369A (zh) * 2017-02-16 2018-08-24 新疆唐庭霞露酒庄有限公司 一种冰葡萄酒的制备方法
JP7356348B2 (ja) 2017-02-24 2023-10-04 コーンプロダクツ ディベロップメント インコーポレーテッド 製麦におけるステビオール配糖体の使用
EP3592138A4 (en) 2017-03-08 2020-11-25 PureCircle USA Inc. CULTIVARS OF STEVIA PLANTS WITH HIGH REBAUDIOSIDE M CONTENT AND THEIR PRODUCTION PROCESSES
CA3063742A1 (en) * 2017-05-15 2018-11-22 Purecircle Usa Inc. High-purity steviol glycosides
WO2018213290A1 (en) * 2017-05-15 2018-11-22 Purecircle Usa Inc. High-purity steviol glycosides
JP7116751B2 (ja) 2017-06-30 2022-08-10 コナゲン インコーポレイテッド β－グルコシダーゼによるステビオール配糖体の加水分解
US11432573B2 (en) * 2017-07-27 2022-09-06 Franco Cavaleri Food and beverage sweeteners
BR112020002708A2 (pt) 2017-08-11 2020-08-25 Amyris, Inc. célula hospedeira, métodos para produzir ácido caurenoico, rebaudiosídeo d, rebaudiosídeo m e glicosídeo de esteviol, composição de fermentação, caureno oxidase de ocorrência não natural, e, ácido nucleico de ocorrência não natural
CN109423486B (zh) * 2017-08-29 2022-02-25 中国科学院分子植物科学卓越创新中心 新型udp-糖基转移酶及其应用
US11365417B2 (en) 2017-09-12 2022-06-21 Bio Capital Holdings, LLC Biological devices and methods of use thereof to produce steviol glycosides
WO2019090336A1 (en) * 2017-11-06 2019-05-09 Purecircle Usa Inc. High-purity steviol-glycosides
EP3710488A4 (en) * 2017-11-14 2021-08-25 PureCircle USA Inc. STEVIA MOLECULES, METHOD FOR MANUFACTURING SUCH MOLECULES AND USES THEREOF
WO2019178116A1 (en) * 2018-03-12 2019-09-19 Conagen Inc. Biosynthetic production of steviol glycosides rebaudioside j and rebaudioside n
JP7402168B2 (ja) * 2018-03-14 2023-12-20 ザ コカ・コーラ カンパニー ステビアブレンドを含む濃縮物および使用
WO2019178471A1 (en) * 2018-03-16 2019-09-19 Purecircle Usa Inc. High-purity steviol glycosides
CA3094205A1 (en) * 2018-03-16 2019-09-19 Purecircle Usa Inc. High-purity steviol glycosides
AU2018413277B2 (en) * 2018-03-16 2024-07-11 Purecircle Usa Inc. High-purity steviol glycosides
CA3100539A1 (en) 2018-05-17 2019-11-21 The Coca-Cola Company Process for preparing concentrated solutions of steviol glycosides, and uses
CN108753748B (zh) * 2018-06-08 2021-12-10 中国中医科学院中药研究所 大黄素糖基转移酶蛋白FtUGT75R2及其编码基因与应用
KR102392728B1 (ko) * 2018-06-28 2022-04-29 주식회사 삼양사 말토올리고당을 포함하는 혼합당 조성물
EP3830106A4 (en) 2018-07-30 2022-07-06 Codexis, Inc. MANIPULATED GLYCOSYLTRANSFERASES AND METHODS FOR STEVIOL GLYCOSIDE GLUCOSYLATION
WO2020064788A1 (en) * 2018-09-29 2020-04-02 Firmenich Sa Terpene glycoside derivatives and uses thereof
EP3867370A1 (en) 2018-10-15 2021-08-25 Amyris, Inc. Stevia rebaudiana kaurenoic acid hydroxylase variants for high efficiency production of rebaudiosides
EP3877519A4 (en) 2018-11-09 2022-08-24 Ginkgo Bioworks, Inc. BIOSYNTHESIS OF MOGROSIDS
AU2020211408A1 (en) 2019-01-24 2021-08-12 Amyris, Inc. ABC transporters for the high efficiency production of rebaudiosides
CN109750072B (zh) * 2019-01-31 2022-04-19 南京工业大学 一种酶法制备莱鲍迪苷e的方法
CN109750071A (zh) * 2019-01-31 2019-05-14 南京工业大学 一种生物催化合成莱鲍迪苷m的方法
CA3130257A1 (en) * 2019-02-15 2020-08-20 Purecircle Usa Inc. High-purity steviol glycosides
BR112021019734A2 (pt) * 2019-04-01 2022-03-08 Coca Cola Co Composições contendo brazeína
US12065685B1 (en) 2019-05-13 2024-08-20 Amyris, Inc. UDP-glycosyltransferase variants and uses thereof
US20220228186A1 (en) * 2019-05-23 2022-07-21 Arzeda Corp. Compositions and methods for producing steviol glycosides
CN112080480B (zh) * 2019-06-14 2023-01-03 中国科学院分子植物科学卓越创新中心 糖基转移酶突变体及其应用
CN110669809B (zh) * 2019-11-12 2022-12-23 广西师范大学 一种酶法制备罗汉果苷iv和苷v的方法
EP4040986B1 (en) * 2019-12-13 2025-12-24 Firmenich Incorporated Taste modifying compositions and uses thereof
CN111187316B (zh) * 2020-02-14 2021-06-15 南京全凯生物基材料研究院有限公司 一种从甜菊糖母液中提取莱包迪苷d和莱包迪苷m的方法
AU2021258172A1 (en) * 2020-04-20 2022-11-17 Cargill, Incorporated Steviol glycoside malonic acid esters
US20230172235A1 (en) * 2020-05-07 2023-06-08 The Coca-Cola Company Beverages comprising rebaudioside am and rebaudioside m with enhanced flavor
CN112760302B (zh) * 2020-12-23 2022-08-26 中化健康产业发展有限公司 一种能够催化莱鲍迪苷A生成莱鲍迪苷D的糖基转移酶StUGT
JP2022103561A (ja) * 2020-12-28 2022-07-08 サントリーホールディングス株式会社 Ｄ－アラビノースを含む飲料
CN117616129A (zh) * 2021-02-17 2024-02-27 阿泽达公司 用于产生莱苞迪苷d的组合物和方法
JP7210626B2 (ja) * 2021-02-18 2023-01-23 ペプシコ・インク 酵素的方法を使用してレバウディオサイドｊを調製するための方法
JP2024508795A (ja) 2021-03-01 2024-02-28 カーギル インコーポレイテッド キシロシル化ステビオールグリコシド及び酵素的産生方法
MX2023012997A (es) * 2021-05-04 2024-01-11 Coca Cola Co Bebidas que comprenden sales con sabor mejorado.
CN115611969B (zh) * 2021-07-14 2025-10-17 潍坊康地恩生物科技有限公司 一种索马甜突变体及其应用
TW202342764A (zh) * 2021-10-19 2023-11-01 南韓商Ｃｊ第一製糖股份有限公司 用於製備甜菊糖雙苷d及甜菊糖雙苷m的方法
CN115558651B (zh) * 2021-12-30 2025-08-22 中化健康产业发展有限公司 一种能够催化莱鲍迪苷A生成多种甜菊糖苷衍生物的糖基转移酶CaUGT
CN114921431B (zh) * 2022-05-05 2023-04-25 湖北大学 糖基转移酶突变体及其在发酵生产芳香醇糖苷中的应用
CN114875054B (zh) * 2022-06-24 2023-11-17 南京工业大学 一种酶法制备糖基化甜菊糖苷类化合物的方法及其衍生物
WO2024042405A1 (en) 2022-08-26 2024-02-29 Amyris Bio Products Portugal, Unipessoal, Ltda. Compositions and methods for the synthesis of bio-based polymers
WO2024042486A1 (en) 2022-08-26 2024-02-29 Amyris Bio Products Portugal, Unipessoal, Ltda. Compositions and methods for the production of polyurethanes
CN118126977A (zh) * 2022-12-01 2024-06-04 南京工业大学 一种糖基转移酶突变体及其催化合成甜茶苷衍生物Rub2G的方法
EP4627098A1 (en) 2022-12-02 2025-10-08 Amyris Bio Products Portugal, Unipessoal, LDA Compositions and methods for using previously cultured cells
CN116462777B (zh) * 2023-04-14 2023-11-17 桂林莱茵合成生物技术有限公司 一种新型葡萄糖基甜菊糖苷rmm及其应用、合成方法
WO2024228615A1 (en) 2023-05-03 2024-11-07 Purecircle Sdn. Bhd. High-purity steviol glycosides
JP2025534044A (ja) * 2023-06-30 2025-10-09 ドンタイ ハオルイ バイオテクノロジー カンパニー リミテッド 糖転移酵素ｕｇｔｓｌ２突然変異体、糖転移酵素突然変異体及びそのレバウディオサイドｍ２を合成する方法
CN117256832A (zh) * 2023-09-19 2023-12-22 领航食品(肇庆)有限公司 一种罗汉果甜苷的制备方法及其应用
CN117717136B (zh) * 2024-02-05 2025-11-18 温州大学 一种透明质酸钠饮品及其制备方法和应用
WO2026006475A1 (en) * 2024-06-25 2026-01-02 Arzeda Corp. Compositions and methods for glycosylation of steviol glycosides

Family Cites Families (203)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3030481A (en) 1957-12-23 1962-04-17 S & C Electric Co Switch construction
US3017168A (en) 1959-01-26 1962-01-16 Phillips Petroleum Co In situ retorting of oil shale
US3723410A (en) 1970-12-01 1973-03-27 Amazon Natural Drug Co Method of producing stevioside
JPS51142570A (en) 1975-06-04 1976-12-08 Morita Kagaku Kogyo Method of imparting sweetness to food or pharmaceutical agent
JPS525800A (en) 1975-06-27 1977-01-17 Sanyo Kokusaku Pulp Co Ltd Method of purifying stevioside
JPS5283731A (en) 1976-01-01 1977-07-12 Ajinomoto Co Inc Rebaudiosides
JPS52100500A (en) 1976-02-18 1977-08-23 Japan Organo Co Ltd Purification and concentration of aqueous stevioside extract
JPS52136200A (en) 1976-05-12 1977-11-14 Daicel Chem Ind Ltd Extraction purification of stevioside
JPS5338669A (en) 1976-09-16 1978-04-08 Toyo Soda Mfg Co Ltd Separation of natural sweetening agent
JPS5430199A (en) 1977-08-08 1979-03-06 Sanyo Kokusaku Pulp Co Ltd Purification of stevia sweetening agnet
JPS54132599A (en) 1978-04-04 1979-10-15 Sanyo Kokusaku Pulp Co Ltd Separation and purification of stevioside sweetening
US4219571A (en) 1978-06-15 1980-08-26 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Process for producing a sweetener
JPS5539731A (en) 1978-09-11 1980-03-19 Res Inst For Prod Dev Extraction of stevioside
JPS5581567A (en) 1978-12-13 1980-06-19 Res Inst For Prod Dev Extraction and purification of stevioside
JPS5592400A (en) 1978-12-29 1980-07-12 Daikin Ind Ltd Purification of stevioside
JPS55120770A (en) 1979-03-14 1980-09-17 Chisso Corp Purification of stevioside solution
JPS55138372A (en) 1979-04-13 1980-10-29 Chisso Corp Purification of stevioside solution
JPS55162953A (en) 1979-06-04 1980-12-18 Yamada Masami Preparation of stevioside
JPS607108B2 (ja) 1979-11-13 1985-02-22 不二サッシ株式会社 カ−テンウオ−ルの改装工法
JPS5699768A (en) 1980-01-09 1981-08-11 Hayashibara Biochem Lab Inc Preparation of steviol glycoside
JPS56109568A (en) 1980-02-01 1981-08-31 Maruzen Kasei Kk Purification of stevia sweetening substance
JPS56121453A (en) 1980-02-27 1981-09-24 Ajinomoto Co Inc Separation of stevioside and rebaudioside a
JPS56121454A (en) 1980-02-27 1981-09-24 Ajinomoto Co Inc Separation of stevioside and rebaudioside a by crystallization
JPS56121455A (en) 1980-02-27 1981-09-24 Ajinomoto Co Inc Separation of stevioside and rebaudioside a by crystallization
JPS56160962A (en) 1980-05-14 1981-12-11 Dick Fine Chem Kk Purification of solution containing stevioside-type sweetening substance
JPS55159770A (en) 1980-05-26 1980-12-12 Res Inst For Prod Dev Extraction and purification of stevioside
JPS572656A (en) 1980-06-05 1982-01-08 Shinnakamura Kagaku Kogyo Kk Decoloration and purification of stevia extract
JPS575663A (en) 1980-06-13 1982-01-12 Res Inst For Prod Dev Purification of stevioside through extraction
JPS5746998A (en) 1980-09-04 1982-03-17 Fuji Food:Kk Preparation of stevioside
US4454290A (en) 1980-09-22 1984-06-12 Dynapol Stevioside analogs
JPS5775992A (en) 1980-10-30 1982-05-12 Tama Seikagaku Kk Purification of stevioside
JPS5846310B2 (ja) 1980-11-19 1983-10-15 丸善化成株式会社 ステビア中の主要甘味成分を単離する方法
JPS57134498A (en) 1981-02-12 1982-08-19 Hayashibara Biochem Lab Inc Anhydrous crystalline maltitol and its preparation and use
US4361697A (en) 1981-05-21 1982-11-30 F. K. Suzuki International, Inc. Extraction, separation and recovery of diterpene glycosides from Stevia rebaudiana plants
JPS5820170A (ja) 1981-07-24 1983-02-05 Toshizo Fukushima 甘味料の製法
JPS5828246A (ja) 1981-08-10 1983-02-19 Mitsubishi Acetate Co Ltd ステビオサイドの製造方法
JPS5828247A (ja) 1981-08-10 1983-02-19 Mitsubishi Acetate Co Ltd ステビオサイド溶液の精製方法
JPS58149697A (ja) 1982-02-27 1983-09-06 Dainippon Ink & Chem Inc β−１，３グリコシルステビオシドの製造方法
JPS58212759A (ja) 1982-06-04 1983-12-10 Sekisui Chem Co Ltd ステビア甘味物質の精製方法
JPS58212760A (ja) 1982-06-04 1983-12-10 Sekisui Chem Co Ltd ステビア甘味物質の精製方法
JPS5945848A (ja) 1982-09-09 1984-03-14 Morita Kagaku Kogyo Kk 新天然甘味料の製造方法
GB8403612D0 (en) * 1984-02-10 1984-03-14 Tate & Lyle Plc Sweetener
US4612942A (en) 1984-03-08 1986-09-23 Stevia Company, Inc. Flavor enhancing and modifying materials
US4657638A (en) 1985-07-29 1987-04-14 University Of Florida Distillation column
US4599403A (en) 1985-10-07 1986-07-08 Harold Levy Method for recovery of stevioside
JPS62166861A (ja) 1986-01-20 1987-07-23 Sanpack:Kk ステビア乾葉からの甘味成分抽出・精製法
EP0302948B1 (de) 1987-07-21 1993-12-01 Roger H. Giovanetto Verfahren zur Gewinnung von Steviosiden aus pflanzlichem Rohmaterial
JP3111203B2 (ja) 1987-12-26 2000-11-20 中里 隆憲 ステビア新品種に属する植物
DE3810681A1 (de) 1988-03-29 1989-10-12 Udo Kienle Verfahren zur herstellung eines natuerlichen suessungsmittels auf der basis von stevia rebaudiana und seine verwendung
JP2898688B2 (ja) 1990-03-14 1999-06-02 日本製紙株式会社 高甘味糖付加ステビア甘味料及びその製法
CN1024348C (zh) 1990-05-23 1994-04-27 孟凡彬 用普通树脂提取甜菊甙的新工艺
US5576042A (en) 1991-10-25 1996-11-19 Fuisz Technologies Ltd. High intensity particulate polysaccharide based liquids
JPH067108A (ja) 1992-06-23 1994-01-18 P C C Technol:Kk ステビア甘味物質の抽出分離方法
JPH06192283A (ja) 1992-12-17 1994-07-12 Ikeda Pan:Kk 純粋なレバウディオサイドａを生産する方法
CN1032651C (zh) 1993-09-21 1996-08-28 袁斯鸣 甜菊糖甙的精制方法
JP3436317B2 (ja) 1993-11-24 2003-08-11 大日本インキ化学工業株式会社 ステビア甘味料の製造方法
JPH07177862A (ja) 1993-12-24 1995-07-18 Morita Kagaku Kogyo Kk 水難溶性甘味料
US5549757A (en) 1994-06-10 1996-08-27 Ingredient Technology Corporation Process for recrystallizing sugar and product thereof
JPH08214A (ja) 1994-06-17 1996-01-09 Ikeda Pan:Kk レバウディオサイドａ系甘味料およびその製造方法
JP3262458B2 (ja) 1994-07-29 2002-03-04 キヤノン株式会社 記録装置
CN1112565A (zh) 1995-03-06 1995-11-29 北京市环境保护科学研究院 膜法组合技术提取甜菊甙工艺
JP3352860B2 (ja) 1995-10-19 2002-12-03 守田化学工業株式会社 α−グルコシル化ステビア甘味料
RU2111969C1 (ru) 1995-11-08 1998-05-27 Республиканская научно-исследовательская лаборатория по биологически активным веществам Способ получения стевиозида
US5962678A (en) * 1996-09-13 1999-10-05 Alberta Research Council Method of extracting selected sweet glycosides from the Stevia rebaudiana plant
TW557327B (en) 1996-11-08 2003-10-11 Hayashibara Biochem Lab Kojibiose phosphorylase, its preparation and uses
JP2002262822A (ja) 1997-01-30 2002-09-17 Morita Kagaku Kogyo Kk 種子栽培可能なステビア品種の植物体から得られる甘味料
JPH10271928A (ja) 1997-01-30 1998-10-13 Morita Kagaku Kogyo Kk ステビア・レバウディアナ・ベルトニーに属する新植物
RU2156083C2 (ru) 1997-06-24 2000-09-20 Дмитриенко Николай Васильевич Способ получения экстракта из травы стевии
RU2123267C1 (ru) 1997-06-24 1998-12-20 Дмитриенко Николай Васильевич Способ получения концентрата экстракта из порошка травы стевии
JPH1131191A (ja) 1997-07-14 1999-02-02 Olympus Optical Co Ltd マルチメディア情報読取装置
US5972120A (en) 1997-07-19 1999-10-26 National Research Council Of Canada Extraction of sweet compounds from Stevia rebaudiana Bertoni
JP3646497B2 (ja) 1997-12-22 2005-05-11 味の素株式会社 顆粒状甘味料
CN1078217C (zh) 1998-02-18 2002-01-23 南开大学 吸附树脂法从甜菊糖中富集、分离菜鲍迪甙a
GB9808579D0 (en) * 1998-04-22 1998-06-24 Novartis Nutrition Ag Improvements in or relating to organic compounds
CN1098860C (zh) 1998-06-08 2003-01-15 江苏省中国科学院植物研究所 高品质甜菊糖甙分离富集工艺
JP2000236842A (ja) 1998-12-24 2000-09-05 Nippon Paper Industries Co Ltd ステビア甘味料
US6228996B1 (en) 1999-02-24 2001-05-08 James H. Zhou Process for extracting sweet diterpene glycosides
RU2167544C2 (ru) 1999-03-09 2001-05-27 Краснодарский научно-исследовательский институт хранения и переработки сельскохозяйственной продукции Способ получения экстракта из растения stevia rebaudiana bertoni для виноделия
US20020132320A1 (en) 2001-01-10 2002-09-19 Wang Peng George Glycoconjugate synthesis using a pathway-engineered organism
RU2198548C1 (ru) 2001-06-01 2003-02-20 Общество с ограниченной ответственностью Научно-производственное холдинговое объединение "СТЕВИЯ-АГРОМЕДФАРМ" Способ получения экстракта из растения stevia rebaudiana bertoni
CN1132840C (zh) 2001-10-24 2003-12-31 青岛创升生物科技有限公司 甜菊糖甙的精制方法
MX264256B (es) 2002-02-14 2009-02-03 Novozymes As Proceso para producir hidrolizado de almidon.
SE0200539D0 (sv) 2002-02-25 2002-02-25 Metcon Medicin Ab Granulation process and starch granulate
US6855526B2 (en) * 2002-05-15 2005-02-15 The United States Of America As Represented By The Secretary Of Agriculture Method for making mannitol with Lactobacillus intermedius
CN1237182C (zh) 2002-06-25 2006-01-18 山东华仙甜菊股份有限公司 一种甜菊糖味质的改善方法
MXPA05009353A (es) 2003-03-10 2005-11-04 Genencor Int Composiciones de grano que contienen isomalto-oligosacaridos pre-bioticos y metodos para la elaboracion y uso de las mismas.
US20110097443A1 (en) 2004-03-17 2011-04-28 Ting Liu Carlson Low glycemic sweeteners and products made using the same
US7476248B2 (en) 2004-04-06 2009-01-13 Alcon, Inc. Method of calculating the required lens power for an opthalmic implant
AU2005273544B2 (en) * 2004-08-18 2011-02-10 H C L Manufacturers Pty Ltd Herbal compositions for the prevention or treatment of urinary incontinence and overactive bladder
US7923552B2 (en) 2004-10-18 2011-04-12 SGF Holdings, LLC High yield method of producing pure rebaudioside A
US7838044B2 (en) 2004-12-21 2010-11-23 Purecircle Sdn Bhd Extraction, separation and modification of sweet glycosides from the Stevia rebaudiana plant
US20060142555A1 (en) 2004-12-23 2006-06-29 Council Of Scientific And Industrial Research Process for production of steviosides from stevia rebaudiana bertoni
WO2006072878A1 (en) 2005-01-07 2006-07-13 Ranbaxy Laboratories Limited Oral dosage forms of sertraline having controlled particle size and processes for their preparation
WO2006072879A1 (en) 2005-01-07 2006-07-13 Ranbaxy Laboratories Limited Preparation of sweetener tablets of stevia extract by dry granulation methods
US7838011B2 (en) 2005-02-14 2010-11-23 Pankaj Modi Stabilized protein compositions for topical administration and methods of making same
US8613910B2 (en) * 2005-07-27 2013-12-24 Merck Patent Gmbh Flavonoids as synergists for enhancing the action of self-tanning substances
US8318459B2 (en) 2011-02-17 2012-11-27 Purecircle Usa Glucosyl stevia composition
US8337927B2 (en) 2005-10-11 2012-12-25 Purecircle Sdn Bhd Process for manufacturing a sweetener and use thereof
US8334006B2 (en) 2005-10-11 2012-12-18 Purecircle Sdn Bhd Process for manufacturing a sweetener and use thereof
US8790730B2 (en) 2005-10-11 2014-07-29 Purecircle Usa Process for manufacturing a sweetener and use thereof
US7807206B2 (en) 2005-10-11 2010-10-05 Purecircle Sdn Bhd Sweetner and use
US8318232B2 (en) 2005-10-11 2012-11-27 Purecircle Sdn Bhd Sweetner and use
US8257948B1 (en) 2011-02-17 2012-09-04 Purecircle Usa Method of preparing alpha-glucosyl Stevia composition
US8298599B2 (en) 2005-10-11 2012-10-30 Purecircle Sdn Bhd Process for manufacturing a sweetener and use thereof
US9386797B2 (en) 2011-02-17 2016-07-12 Purecircle Sdn Bhd Glucosyl stevia composition
US7862845B2 (en) 2005-10-11 2011-01-04 Purecircle Sdn Bhd Process for manufacturing a sweetener and use thereof
US8956677B2 (en) 2005-11-23 2015-02-17 The Coca-Cola Company High-potency sweetener composition with glucosamine and compositions sweetened therewith
US20070116823A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company High-potency sweetener for hydration and sweetened hydration composition
US20070116831A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company Dental Composition with High-Potency Sweetener
US8512789B2 (en) 2005-11-23 2013-08-20 The Coca-Cola Company High-potency sweetener composition with dietary fiber and compositions sweetened therewith
US8945652B2 (en) 2005-11-23 2015-02-03 The Coca-Cola Company High-potency sweetener for weight management and compositions sweetened therewith
MX2008006583A (es) 2005-11-23 2008-05-31 Coca Cola Co Composiciones de edulcorante natural de alta potencia, con perfil de sabor y/o perfil temporal mejorado, metodos para su formulacion, y usos
US8940351B2 (en) 2005-11-23 2015-01-27 The Coca-Cola Company Baked goods comprising high-potency sweetener
US20070134391A1 (en) 2005-11-23 2007-06-14 The Coca-Cola Company High-Potency Sweetener Composition for Treatment and/or Prevention of Autoimmune Disorders and Compositions Sweetened Therewith
US8956678B2 (en) 2005-11-23 2015-02-17 The Coca-Cola Company High-potency sweetener composition with preservative and compositions sweetened therewith
US20070116825A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company Confection with High-Potency Sweetener
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US20070116833A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition with Calcium and Compositions Sweetened Therewith
US20070116836A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition for Treatment and/or Prevention of Osteoporosis and Compositions Sweetened Therewith
US8377491B2 (en) 2005-11-23 2013-02-19 The Coca-Cola Company High-potency sweetener composition with vitamin and compositions sweetened therewith
US8435587B2 (en) 2005-11-23 2013-05-07 The Coca-Cola Company High-potency sweetener composition with long-chain primary aliphatic saturated alcohol and compositions sweetened therewith
US20070116800A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company Chewing Gum with High-Potency Sweetener
US20070116839A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition With C-Reactive Protein Reducing Substance and Compositions Sweetened Therewith
US9144251B2 (en) 2005-11-23 2015-09-29 The Coca-Cola Company High-potency sweetener composition with mineral and compositions sweetened therewith
US8993027B2 (en) 2005-11-23 2015-03-31 The Coca-Cola Company Natural high-potency tabletop sweetener compositions with improved temporal and/or flavor profile, methods for their formulation, and uses
US8367138B2 (en) 2005-11-23 2013-02-05 The Coca-Cola Company Dairy composition with high-potency sweetener
US8524304B2 (en) 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with probiotics/prebiotics and compositions sweetened therewith
US8962058B2 (en) 2005-11-23 2015-02-24 The Coca-Cola Company High-potency sweetener composition with antioxidant and compositions sweetened therewith
US8435588B2 (en) 2005-11-23 2013-05-07 The Coca-Cola Company High-potency sweetener composition with an anti-inflammatory agent and compositions sweetened therewith
US8524303B2 (en) 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with phytosterol and compositions sweetened therewith
US8367137B2 (en) 2005-11-23 2013-02-05 The Coca-Cola Company High-potency sweetener composition with fatty acid and compositions sweetened therewith
US20070116820A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company Edible gel compositions comprising high-potency sweeteners
US20070116829A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company Pharmaceutical Composition with High-Potency Sweetener
US8940350B2 (en) 2005-11-23 2015-01-27 The Coca-Cola Company Cereal compositions comprising high-potency sweeteners
US20070116822A1 (en) 2005-11-23 2007-05-24 The Coca-Cola Company High-potency sweetener composition with saponin and compositions sweetened therewith
US7927851B2 (en) 2006-03-21 2011-04-19 Vineland Research And Innovation Centre Compositions having ent-kaurenoic acid 13-hydroxylase activity and methods for producing same
US8791253B2 (en) 2006-06-19 2014-07-29 The Coca-Cola Company Rebaudioside A composition and method for purifying rebaudioside A
US9012626B2 (en) 2006-06-19 2015-04-21 The Coca-Cola Company Rebaudioside a composition and method for purifying rebaudioside a
EP2049673B1 (en) 2006-08-11 2011-04-13 Danisco US Inc. Native grain amylases in enzyme combinations for granular starch hydrolysis
CN101541294B (zh) 2006-09-20 2013-01-23 株式会社汤山制作所 药剂包装装置
FR2906712B1 (fr) 2006-10-09 2025-02-28 France Chirurgie Instr Bouchon meatique a pose simplifiee.
FR2906973B1 (fr) 2006-10-17 2009-01-16 Roquette Freres Composition edulcorante granulee
US20080102497A1 (en) 2006-10-31 2008-05-01 Dominic Wong Enzymatic hydrolysis of starch
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
US20080107787A1 (en) 2006-11-02 2008-05-08 The Coca-Cola Company Anti-Diabetic Composition with High-Potency Sweetener
US9101161B2 (en) 2006-11-02 2015-08-11 The Coca-Cola Company High-potency sweetener composition with phytoestrogen and compositions sweetened therewith
FI20070521A7 (fi) 2006-11-10 2008-05-11 Atacama Labs Oy Rakeita, tabletteja ja rakeistusmenetelmä
CN101200480B (zh) 2006-12-15 2011-03-30 成都华高药业有限公司 莱鲍迪甙a的提取方法
ATE547953T1 (de) 2007-01-22 2012-03-15 Cargill Inc Verfahren zur herstellung gereinigter rebaudiosid-a-zusammensetzungen durch solvent/antisolvent- kristallisation
US9877500B2 (en) 2007-03-14 2018-01-30 Concentrate Manufacturing Company Of Ireland Natural beverage products
BRPI0701736A (pt) 2007-04-05 2008-07-15 Stevia Natus Produtos Naturais processo industrial fìsico-quìmico de obtenção de edulcorantes naturais e princìpios ativos puros de steviosìdeo e rebaudiosìdeo a, a partir da folha de plantas de stévia, sem a utilização de solventes orgánicos para fabricação de adoçantes
CN101932719B (zh) 2007-04-26 2014-04-02 株式会社林原 支链α-葡聚糖及生成其的α-葡糖基转移酶和它们的制造方法以及用途
US8030481B2 (en) 2007-05-21 2011-10-04 The Coca-Cola Company Stevioside polymorphic and amorphous forms, methods for their formulation, and uses
US20080292765A1 (en) 2007-05-22 2008-11-27 The Coca-Cola Company Sweetness Enhancers, Sweetness Enhanced Sweetener Compositions, Methods for Their Formulation, and Uses
US20080292775A1 (en) 2007-05-22 2008-11-27 The Coca-Cola Company Delivery Systems for Natural High-Potency Sweetener Compositions, Methods for Their Formulation, and Uses
US8709521B2 (en) 2007-05-22 2014-04-29 The Coca-Cola Company Sweetener compositions having enhanced sweetness and improved temporal and/or flavor profiles
ES2527113T3 (es) 2007-06-29 2015-01-20 Mcneil Nutritionals, Llc Edulcorantes de mesa que contienen estevia y procedimientos de producción de los mismos
US7964232B2 (en) 2007-09-17 2011-06-21 Pepsico, Inc. Steviol glycoside isomers
TWI475963B (zh) 2008-02-25 2015-03-11 可口可樂公司 甜菊糖苷ａ衍生性產物以及製造彼的方法
FR2929533B1 (fr) 2008-04-03 2010-04-30 Novasep Procede de separation multicolonnes a gradient.
US20110033525A1 (en) 2008-04-11 2011-02-10 Zhijun Liu Diterpene Glycosides as Natural Solubilizers
US8321670B2 (en) 2008-07-11 2012-11-27 Bridgewater Systems Corp. Securing dynamic authorization messages
CN102216313A (zh) 2008-10-03 2011-10-12 守田化学工业株式会社 新的甜菊醇糖苷
WO2010054829A1 (en) 2008-11-14 2010-05-20 Cargill, Incorporated Improving the mouthfeel of beverages
US20120058236A1 (en) 2009-04-09 2012-03-08 Cargill Incorporated Sweetener composition comprising high solubility form of rebaudioside a and method of making
BRPI1010766A2 (pt) 2009-06-16 2015-09-22 Epc Beeijing Natural Products Co Ltd processo para rebaudiosídeo d
US8414950B2 (en) * 2009-10-15 2013-04-09 Purecircle Sdn Bhd High-purity rebaudioside D and low-calorie table top tablet containing the same
US8299224B2 (en) 2009-10-15 2012-10-30 Purecircle Sdn Bhd High-purity Rebaudioside D
CA2775732C (en) 2009-10-15 2018-10-09 Purecircle Sdn Bhd High-purity rebaudioside d and applications
US8703224B2 (en) 2009-11-04 2014-04-22 Pepsico, Inc. Method to improve water solubility of Rebaudioside D
US20110111115A1 (en) 2009-11-06 2011-05-12 Jingang Shi Rebaudioside a polymorphs and methods to prepare them
ES2707280T3 (es) 2009-11-12 2019-04-03 Purecircle Usa Inc Granulación de un edulcorante a base de estevia
CN104855925B (zh) * 2009-12-28 2017-04-26 可口可乐公司 甜味增强剂，其组合物，及使用方法
US20110189360A1 (en) 2010-02-04 2011-08-04 Pepsico, Inc. Method to Increase Solubility Limit of Rebaudioside D in an Aqueous Solution
EP2533651A1 (en) * 2010-02-08 2012-12-19 The Coca-Cola Company Solubility enhanced terpene glycoside(s)
NZ604915A (en) 2010-06-02 2014-10-31 Evolva Nutrition Inc Recombinant production of steviol glycosides
WO2012075030A1 (en) 2010-11-30 2012-06-07 Massachusetts Institute Of Technology Microbial production of natural sweeteners, diterpenoid steviol glycosides
WO2012082493A1 (en) 2010-12-13 2012-06-21 Cargill, Incorporated Crystalline forms of rebaudioside b
CA2821116C (en) 2010-12-13 2021-01-19 Ting Liu Carlson Glycoside blends
BR112013014814B1 (pt) 2010-12-24 2019-09-03 Daicel Corp processo para produzir ácido acético
US9603373B2 (en) 2011-02-17 2017-03-28 Purecircle Sdn Bhd Glucosyl stevia composition
CN103732753B (zh) 2011-08-08 2018-03-30 埃沃尔瓦公司 甜菊醇糖苷类的重组生产
WO2013041236A1 (en) * 2011-09-22 2013-03-28 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Sweetener compositions, methods of making same and consumables containing same
CN103159808B (zh) 2011-12-09 2017-03-29 上海泓博智源医药股份有限公司 一种制备天然甜味剂的工艺方法
EP3345490B1 (en) 2011-12-19 2023-11-08 The Coca-Cola Company Beverage comprising rebaudioside x
WO2013110673A1 (en) 2012-01-23 2013-08-01 Dsm Ip Assets B.V. Diterpene production
US9752174B2 (en) * 2013-05-28 2017-09-05 Purecircle Sdn Bhd High-purity steviol glycosides
CN110358795B (zh) * 2012-05-22 2024-12-03 谱赛科有限责任公司 高纯度的甜菊醇糖苷
CN102766667B (zh) * 2012-08-14 2014-06-11 成都南诺格生物科技有限责任公司 甜菊苷转化为莱鲍迪苷e的方法
JP6192283B2 (ja) 2012-10-11 2017-09-06 スリーエム イノベイティブ プロパティズ カンパニー ファスナ部材
US20140122227A1 (en) * 2012-10-25 2014-05-01 Microsoft Corporation Targeting marketing messages based on user preferences
EP3892728A1 (en) 2013-02-06 2021-10-13 Evolva SA Methods for improved production of rebaudioside d and rebaudioside m
SG10201705993YA (en) 2013-02-11 2017-08-30 Evolva Sa Efficient production of steviol glycosides in recombinant hosts
US20140342044A1 (en) * 2013-05-14 2014-11-20 Pepsico, Inc. Compositions and Comestibles
US10952458B2 (en) 2013-06-07 2021-03-23 Purecircle Usa Inc Stevia extract containing selected steviol glycosides as flavor, salty and sweetness profile modifier
EP3024941B1 (en) 2013-07-23 2019-07-03 DSM IP Assets B.V. Diterpene production in yarrowia
CN103397064B (zh) 2013-08-14 2015-04-15 苏州汉酶生物技术有限公司 一种酶法制备瑞鲍迪甙m的方法
EP3111775B1 (en) * 2014-02-24 2019-01-09 Suntory Holdings Limited Carbonated beverage containing high-intensity sweetener
US9522929B2 (en) 2014-05-05 2016-12-20 Conagen Inc. Non-caloric sweetener
EP3193636B1 (en) * 2014-09-19 2022-07-06 PureCircle SDN BHD High-purity steviol glycosides
CN105200098A (zh) 2015-06-30 2015-12-30 苏州汉酶生物技术有限公司 一种利用酿酒酵母酶法制备瑞鲍迪甙m的方法
WO2019117315A1 (ja) 2017-12-15 2019-06-20 日本電気株式会社 セルロース系樹脂組成物、成形体及びこれを用いた製品、並びにセルロース系樹脂組成物の製造方法
JP7177862B2 (ja) 2021-01-04 2022-11-24 本田技研工業株式会社 位置決定装置

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