[go: up one dir, main page]

MX2019005315A - Produccion de particulas similares a picornavirus en plantas. - Google Patents

Produccion de particulas similares a picornavirus en plantas.

Info

Publication number
MX2019005315A
MX2019005315A MX2019005315A MX2019005315A MX2019005315A MX 2019005315 A MX2019005315 A MX 2019005315A MX 2019005315 A MX2019005315 A MX 2019005315A MX 2019005315 A MX2019005315 A MX 2019005315A MX 2019005315 A MX2019005315 A MX 2019005315A
Authority
MX
Mexico
Prior art keywords
plant
picornavirus
nucleic acid
pvlp
plants
Prior art date
Application number
MX2019005315A
Other languages
English (en)
Other versions
MX386517B (es
Inventor
Lavoie Pierre-Olivier
Vezina Louis-Philippe
Couture Manon
Poulin Lucie
Andre D'aoust Marc-
Original Assignee
Medicago Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicago Inc filed Critical Medicago Inc
Publication of MX2019005315A publication Critical patent/MX2019005315A/es
Publication of MX386517B publication Critical patent/MX386517B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/125—Picornaviridae, e.g. calicivirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/125—Picornaviridae, e.g. calicivirus
    • A61K39/13—Poliovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/085—Picornaviridae, e.g. coxsackie virus, echovirus, enterovirus
    • C07K16/106—
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32311—Enterovirus
    • C12N2770/32322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32311—Enterovirus
    • C12N2770/32323—Virus like particles [VLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32311—Enterovirus
    • C12N2770/32351—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32611—Poliovirus
    • C12N2770/32623—Virus like particles [VLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32611—Poliovirus
    • C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/22—Vectors comprising a coding region that has been codon optimised for expression in a respective host
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)

Abstract

Se proporciona un método para producir una partícula similar a picornavirus (PVLP) en una planta. El método comprende introducir un primer ácido nucleico y un segundo ácido nucleico en la planta, porción de la planta, o una célula de planta. El primer ácido nucleico comprende una primera región de regulación activa en la planta ligada operativamente a una secuencia de nucleótidos que codifica un polipéptido de picornavirus. El segundo ácido nucleico comprende una segunda región de regulación activa en la planta y ligada operacionalmente a una secuencia de nucleótidos que codifica una o más de proteasas de picornavirus. La planta, porción de la planta, o célula de planta se incuba bajo condiciones que permiten la expresión de los ácidos nucleicos, produciendo de esta manera la PVLP. También se proporciona una PVLP que comprende el polipéptido.
MX2019005315A 2012-09-05 2013-08-29 Produccion de particulas similares a picornavirus en plantas. MX386517B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261697266P 2012-09-05 2012-09-05
PCT/CA2013/050666 WO2014036645A1 (en) 2012-09-05 2013-08-29 Picornavirus-like particle production in plants

Publications (2)

Publication Number Publication Date
MX2019005315A true MX2019005315A (es) 2019-08-05
MX386517B MX386517B (es) 2025-03-19

Family

ID=50236410

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2015002835A MX364778B (es) 2012-09-05 2013-08-29 Produccion de particulas similares a picornavirus en plantas.
MX2019005315A MX386517B (es) 2012-09-05 2013-08-29 Produccion de particulas similares a picornavirus en plantas.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2015002835A MX364778B (es) 2012-09-05 2013-08-29 Produccion de particulas similares a picornavirus en plantas.

Country Status (18)

Country Link
US (2) US10202423B2 (es)
EP (1) EP2893007B1 (es)
JP (3) JP2015528285A (es)
KR (1) KR102134815B1 (es)
CN (1) CN104755614B (es)
AU (1) AU2013312971B2 (es)
BR (1) BR112015004714A2 (es)
CA (1) CA2884073C (es)
ES (1) ES2911774T3 (es)
IL (1) IL237413B (es)
MX (2) MX364778B (es)
MY (2) MY174081A (es)
NZ (1) NZ705488A (es)
PH (1) PH12015500459B1 (es)
RU (1) RU2693431C2 (es)
SG (2) SG10201810400TA (es)
WO (1) WO2014036645A1 (es)
ZA (1) ZA201502264B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7798767B2 (ja) * 2019-12-18 2026-01-14 ジェネトン 植物毛状根からの組換えウイルスベクターの生産

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5428147A (en) 1983-04-15 1995-06-27 Mycogen Plant Science, Inc. Octopine T-DNA promoters
US5100792A (en) 1984-11-13 1992-03-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues
US5036006A (en) 1984-11-13 1991-07-30 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US4962028A (en) 1986-07-09 1990-10-09 Dna Plant Technology Corporation Plant promotors
GB9108386D0 (en) 1991-04-19 1991-06-05 Agricultural Genetics Co Modified plant viruses as vectors
US6392121B1 (en) * 1998-10-07 2002-05-21 Boyce Thompson Institute For Plant Research Gemini virus vectors for gene expression in plants
US7125978B1 (en) 1999-10-04 2006-10-24 Medicago Inc. Promoter for regulating expression of foreign genes
MXPA04003901A (es) * 2001-11-07 2004-07-08 Cytos Biotechnology Ag Disposiciones de antigenos para el tratamiento de enfermedades eosinofilicas alergicas.
WO2008016594A1 (en) 2006-07-31 2008-02-07 The Trustees Of Columbia University In The City Of New York Picornavirus and uses thereof
CA2615372A1 (en) 2007-07-13 2009-01-13 Marc-Andre D'aoust Influenza virus-like particles (vlps) comprising hemagglutinin
GB0800272D0 (en) * 2008-01-08 2008-02-13 Plant Bioscience Ltd Protein expression systems
KR101956910B1 (ko) 2008-01-21 2019-03-12 메디카고 인코포레이티드 헤마글루티닌을 발현하는 트랜스제닉 식물에서 생산된 재조합 인플루엔자 바이러스-유사 입자(ＶＬＰｓ)
EP2328401B8 (en) 2008-08-27 2017-04-19 Arizona Board of Regents for and on behalf of Arizona State University A dna replicon system for high-level rapid production of vaccines and monoclonal antibody therapeutics in plants
US8168192B2 (en) 2008-11-19 2012-05-01 National Chung Hsing University Enterovirus type 71 protein and method for production
TR201803560T4 (tr) 2009-09-22 2019-01-21 Medicago Inc Bitkiden türetilen proteinlerin hazırlanma metotları.
GB0918375D0 (en) * 2009-10-20 2009-12-02 Animal Health Inst Construct
CN101695569A (zh) * 2009-11-03 2010-04-21 中国人民解放军军事医学科学院微生物流行病研究所 一种手足口病单、双价基因工程亚单位疫苗及其制备方法
EP3093025B1 (en) * 2010-03-12 2018-08-01 Merial Inc. Bluetongue virus recombinant vaccines and uses thereof
AR078257A2 (es) 2010-09-01 2011-10-26 Inst Nac De Tecnologia Agropecuaria Inta Composicion para inmunizar mamiferos contra el virus de la aftosa
ES2614527T3 (es) * 2010-11-04 2017-05-31 Medicago Inc. Sistema de expresión en plantas
CN102559615B (zh) * 2010-12-23 2016-09-28 上海泽润生物科技有限公司 Ev71疫苗制备方法及通过该方法制备的疫苗

Also Published As

Publication number Publication date
IL237413A0 (en) 2015-04-30
AU2013312971A1 (en) 2015-03-19
MY174081A (en) 2020-03-09
JP7105131B2 (ja) 2022-07-22
MY196679A (en) 2023-04-29
CN104755614B (zh) 2021-10-01
JP2020171302A (ja) 2020-10-22
MX2015002835A (es) 2015-05-15
US10590173B2 (en) 2020-03-17
PH12015500459B1 (en) 2019-10-25
SG11201501523XA (en) 2015-03-30
WO2014036645A1 (en) 2014-03-13
HK1210208A1 (en) 2016-04-15
CA2884073C (en) 2022-01-18
EP2893007B1 (en) 2022-03-16
KR102134815B1 (ko) 2020-07-17
CN104755614A (zh) 2015-07-01
EP2893007A4 (en) 2016-06-29
JP2015528285A (ja) 2015-09-28
US10202423B2 (en) 2019-02-12
MX364778B (es) 2019-05-06
BR112015004714A2 (pt) 2017-11-21
CA2884073A1 (en) 2014-03-13
EP2893007A1 (en) 2015-07-15
PH12015500459A1 (en) 2015-04-20
RU2693431C2 (ru) 2019-07-02
US20150225462A1 (en) 2015-08-13
NZ705488A (en) 2018-05-25
US20190112341A1 (en) 2019-04-18
ZA201502264B (en) 2020-12-23
KR20150046348A (ko) 2015-04-29
IL237413B (en) 2021-03-25
SG10201810400TA (en) 2018-12-28
MX386517B (es) 2025-03-19
ES2911774T3 (es) 2022-05-20
RU2015109663A (ru) 2016-10-27
JP2018191645A (ja) 2018-12-06
AU2013312971B2 (en) 2019-04-18

Similar Documents

Publication Publication Date Title
AR084726A1 (es) Metodos para aumentar el rendimiento y la produccion de productos quimicos finos en plantas
CL2013002797A1 (es) Método para la fabricación de un fertilizante; sistema de fabricacion de un fertilizante; fertilizante; proceso de preparación de fertilizante
PH12013502600A1 (en) Rabies virus like particle production in plants
CL2012002627A1 (es) Metodos para aumentar la tolerancia al estres abiotico y/o reducir las consecuencias del estres abiotico en plantas que comprende ponerla en contacto con una composicion que contiene acido dicarboxilico o un derivado.
MX390738B (es) Metodo para producir plantas de genoma modificado a partir de protoplastos de planta a alta eficiencia.
MX376138B (es) Produccion de particulas similares a virus de influenza en plantas.
BR112015021708A2 (pt) Inibidor de polipetídeo do tnfa, polinucleotídeo isolado, estrutura de expressão de ácido nucleico, célula de planta, composição farmacêutica e método de produção de um inibidor de polipeptídeo do tnfa
PH12018501452A1 (en) Rotavirus-like particle production in plants
MX2018006627A (es) Aumentar el rendimiento de particulas similares a virus en plantas.
BR112013018516A2 (pt) constructo de ácido nucléico para expressão de alfa-galactosidade em plantas e células de plantas
AR095746A1 (es) Modificación de plantas para producir farneseno y otros terpenoides
CL2019000318A1 (es) Método para producir un l-aminoácido tal como l-lisina.
CL2012002568A1 (es) Metodo para mejorar los rasgos relacionados con el rendimiento en plantas en relación con las plantas control que comprende modular la expresión en una planta de un acido nucleico que codifica un polipeptido tipo cle2; constructo que codifica polipeptido cle2; uso de dicho constructo para producir planta con mayor rendimiento , en particular mayor biomasa y/o mayor rendimiento de semillas.
CL2013003821A1 (es) Polinucleótido que codifica un polipéptido receptor pyr/pyl mutado, casete de expresión que comprende dicho ácido nucleico, y método para producir planta con actividad inhibida de la proteína fosfatasa tipo 2 en ausencia de ácido abscísico.
AR100382A1 (es) Método para producir nailon
AR100122A1 (es) Proteína antiportadora de protones / azúcar tonoplastidaria y su uso para aumentar la concentración de sacarosa de un órgano de almacenamiento de sacarosa de plantas
EA201891335A1 (ru) Добавление аргинина с целью повышения эффективности ацетогенов, ферментирующих газ
MX2019005315A (es) Produccion de particulas similares a picornavirus en plantas.
AR087578A1 (es) Metodos para aumentar el contenido de proteinas, aceites y/o aminoacidos en una planta
CL2012002361A1 (es) Método para mejorar rasgos relacionados con el rendimiento en plantas que comprende modular la expresión en una planta de una molécula de ácido nucleico, vector que comprende, y método de producción dichas plantas transgénicas.
AR092810A1 (es) Plantas que tienen uno o mas rasgos mejorados relacionados con el rendimiento y un metodo para producirlas
AR092811A1 (es) Plantas que tienen uno o mas rasgos mejorados relacionados con el rendimiento y un metodo para producirlas
TH162258A (th) การผลิตอนุภาคคล้ายพิคอร์นาไวรัสในพืช
AR082253A1 (es) Plantas que tienen mejores rasgos relacionados con el rendimiento y un metodo para producirlas
AR083838A1 (es) Plantas que expresan un polipeptido hab1 o kelp que tienen mejores rasgos relacionados con el rendimiento y un metodo para producirlas