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MX2019002498A - Metodos y productos para la expresion de proteinas en celulas. - Google Patents

Metodos y productos para la expresion de proteinas en celulas.

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Publication number
MX2019002498A
MX2019002498A MX2019002498A MX2019002498A MX2019002498A MX 2019002498 A MX2019002498 A MX 2019002498A MX 2019002498 A MX2019002498 A MX 2019002498A MX 2019002498 A MX2019002498 A MX 2019002498A MX 2019002498 A MX2019002498 A MX 2019002498A
Authority
MX
Mexico
Prior art keywords
methods
cells
products
proteins
nucleic acids
Prior art date
Application number
MX2019002498A
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English (en)
Inventor
Matthew Angel
Christopher Rohde
Original Assignee
Factor Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Factor Bioscience Inc filed Critical Factor Bioscience Inc
Publication of MX2019002498A publication Critical patent/MX2019002498A/es

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    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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Abstract

La presente invención se refiere, en parte, a ácidos nucleicos que codifican proteínas, agentes terapéuticos que comprenden ácidos nucleicos que codifican proteínas, métodos para inducir a células a expresar proteínas utilizando ácidos nucleicos, kits y dispositivos para transfectar, realizar la edición genética y reprogramar células, y células, organismos y agentes terapéuticos producidos usando estos métodos, kits y dispositivos. Se describen métodos y productos para alterar la secuencia de ADN de una célula, así como también métodos y productos para inducir a células a expresar proteínas, mediante el uso de moléculas de ARN sintético. También se describen agentes terapéuticos que comprenden ácidos nucleicos que codifican proteínas de edición de genes.
MX2019002498A 2012-11-01 2015-04-27 Metodos y productos para la expresion de proteinas en celulas. MX2019002498A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261721302P 2012-11-01 2012-11-01
US201361785404P 2013-03-14 2013-03-14
US201361842874P 2013-07-03 2013-07-03

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MX2019002498A true MX2019002498A (es) 2021-11-16

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MX2015005346A MX363017B (es) 2012-11-01 2013-11-01 Métodos y productos para la expresión de proteínas en células.
MX2019002498A MX2019002498A (es) 2012-11-01 2015-04-27 Metodos y productos para la expresion de proteinas en celulas.

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MX2015005346A MX363017B (es) 2012-11-01 2013-11-01 Métodos y productos para la expresión de proteínas en células.

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US (19) US9447395B2 (es)
EP (2) EP3786298A1 (es)
JP (5) JP6510416B2 (es)
KR (4) KR102315098B1 (es)
CN (1) CN104769112A (es)
AU (3) AU2013337651B2 (es)
BR (2) BR122019025678B1 (es)
CA (2) CA3150985A1 (es)
MX (2) MX363017B (es)
RU (2) RU2711249C2 (es)
WO (1) WO2014071219A1 (es)

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DE10347710B4 (de) 2003-10-14 2006-03-30 Johannes-Gutenberg-Universität Mainz Rekombinante Impfstoffe und deren Verwendung
DE102005046490A1 (de) 2005-09-28 2007-03-29 Johannes-Gutenberg-Universität Mainz Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
CA2807552A1 (en) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
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