MX2019001412A - Compuestos de 9-aminometil minociclina y usos de los mismos. - Google Patents
Compuestos de 9-aminometil minociclina y usos de los mismos.Info
- Publication number
- MX2019001412A MX2019001412A MX2019001412A MX2019001412A MX2019001412A MX 2019001412 A MX2019001412 A MX 2019001412A MX 2019001412 A MX2019001412 A MX 2019001412A MX 2019001412 A MX2019001412 A MX 2019001412A MX 2019001412 A MX2019001412 A MX 2019001412A
- Authority
- MX
- Mexico
- Prior art keywords
- subject
- minocycline
- propylamino
- dose
- dimethyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
- C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Abstract
Se describen métodos y composiciones para usar un compuesto de tetraciclina para tratar infecciones bacterianas. En una modalidad, por ejemplo, la invención proporciona un método para tratar a un sujeto por una infección, que comprende administrar a dicho sujeto una cantidad eficaz de 9-[(2,2-dimetil-propilamino)-m etil]-minociclina o una sal de la misma, de modo que dicho sujeto sea tratado, en donde la 9-[(2,2-dimetil-propilamino)-metil]-minoc iclina se administra por vía oral a una dosis de aproximadamente 450 mg por día durante dos días consecutivos, luego a una dosis de aproximadamente 300 mg por día durante 5 o más días.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662370527P | 2016-08-03 | 2016-08-03 | |
| US201762514479P | 2017-06-02 | 2017-06-02 | |
| US201762532454P | 2017-07-14 | 2017-07-14 | |
| PCT/US2017/045220 WO2018026987A1 (en) | 2016-08-03 | 2017-08-03 | 9-aminomethyl minocycline compounds and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2019001412A true MX2019001412A (es) | 2019-06-24 |
| MX395671B MX395671B (es) | 2025-03-25 |
Family
ID=61074001
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019001412A MX395671B (es) | 2016-08-03 | 2017-08-03 | Compuestos de 9-aminometil minociclina y usos de los mismos. |
| MX2022011203A MX2022011203A (es) | 2016-08-03 | 2019-02-01 | Compuestos de 9-aminometil minociclina y usos de los mismos. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022011203A MX2022011203A (es) | 2016-08-03 | 2019-02-01 | Compuestos de 9-aminometil minociclina y usos de los mismos. |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US10111890B2 (es) |
| EP (1) | EP3493813A4 (es) |
| JP (3) | JP7225088B2 (es) |
| CN (1) | CN109789153A (es) |
| AU (3) | AU2017305409C1 (es) |
| BR (1) | BR112019001948A2 (es) |
| CA (1) | CA3031790A1 (es) |
| MX (2) | MX395671B (es) |
| MY (1) | MY197146A (es) |
| PH (1) | PH12019500242A1 (es) |
| RU (1) | RU2760186C2 (es) |
| SG (2) | SG10201913574SA (es) |
| TW (2) | TWI746610B (es) |
| WO (1) | WO2018026987A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0908951A2 (pt) * | 2008-03-05 | 2017-01-17 | Paratek Pharm Innc | compostos de minociclina e método de uso dos mesmos |
| SG10201913599RA (en) | 2016-11-01 | 2020-02-27 | Paratek Pharm Innc | 9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (cabp) |
| CN113164456A (zh) * | 2018-09-04 | 2021-07-23 | 帕拉特克药品公司 | 使用四环素化合物治疗分枝杆菌感染的方法 |
| PT117254B (pt) | 2021-05-26 | 2024-04-18 | Hovione Farm S A | Método de síntese de compostos 9-aminometil tetraciclinas |
| WO2023238143A1 (en) * | 2022-06-11 | 2023-12-14 | Gufic Biosciences Limited | A freeze dried parenteral composition of omadacycline tosylate with improved stability |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001043726A1 (en) * | 1999-12-16 | 2001-06-21 | Trident Technologies, Llc | System and method for extended delivery of a therapeutic agent with its receptor loading dose |
| CN101307017A (zh) * | 2002-03-08 | 2008-11-19 | 帕拉特克药品公司 | 氨基-甲基取代的四环素类化合物 |
| US7981930B2 (en) * | 2007-03-13 | 2011-07-19 | Adamas Pharmaceuticals, Inc. | Compositions and kits for treating influenza |
| BRPI0908951A2 (pt) * | 2008-03-05 | 2017-01-17 | Paratek Pharm Innc | compostos de minociclina e método de uso dos mesmos |
| TW202332671A (zh) * | 2008-05-19 | 2023-08-16 | 美商Ｐｒｔｋ Ｓｐｖ２公司 | 四環素化合物之甲苯磺酸鹽及同素異形體 |
| AU2016235151A1 (en) * | 2015-03-24 | 2017-10-12 | Paratek Pharmaceuticals, Inc. | Minocycline compounds for biodefense |
| SG11201808246SA (en) * | 2016-03-24 | 2018-10-30 | Paratek Pharm Innc | Methods for treating and preventing c. difficile infection |
| US10238670B2 (en) * | 2016-05-02 | 2019-03-26 | Paratek Pharmaceuticals, Inc. | 9-aminomethyl minocycline compounds and methods of use thereof in urinary tract infection (UTI) treatment |
-
2017
- 2017-08-02 TW TW106126049A patent/TWI746610B/zh active
- 2017-08-02 TW TW110137764A patent/TW202206081A/zh unknown
- 2017-08-03 MY MYPI2019000487A patent/MY197146A/en unknown
- 2017-08-03 CN CN201780058535.6A patent/CN109789153A/zh active Pending
- 2017-08-03 SG SG10201913574SA patent/SG10201913574SA/en unknown
- 2017-08-03 JP JP2019505163A patent/JP7225088B2/ja active Active
- 2017-08-03 WO PCT/US2017/045220 patent/WO2018026987A1/en not_active Ceased
- 2017-08-03 SG SG11201900379RA patent/SG11201900379RA/en unknown
- 2017-08-03 CA CA3031790A patent/CA3031790A1/en active Pending
- 2017-08-03 BR BR112019001948-0A patent/BR112019001948A2/pt not_active Application Discontinuation
- 2017-08-03 AU AU2017305409A patent/AU2017305409C1/en active Active
- 2017-08-03 EP EP17837652.1A patent/EP3493813A4/en active Pending
- 2017-08-03 MX MX2019001412A patent/MX395671B/es unknown
- 2017-08-03 US US15/667,683 patent/US10111890B2/en active Active
- 2017-08-03 RU RU2019101842A patent/RU2760186C2/ru active
-
2018
- 2018-09-24 US US16/139,346 patent/US20190125767A1/en not_active Abandoned
-
2019
- 2019-02-01 PH PH12019500242A patent/PH12019500242A1/en unknown
- 2019-02-01 MX MX2022011203A patent/MX2022011203A/es unknown
-
2022
- 2022-06-08 AU AU2022203977A patent/AU2022203977A1/en not_active Abandoned
-
2023
- 2023-02-08 JP JP2023017224A patent/JP2023058586A/ja active Pending
-
2024
- 2024-08-05 AU AU2024205530A patent/AU2024205530A1/en active Pending
- 2024-12-26 JP JP2024229728A patent/JP2025041903A/ja active Pending
- 2024-12-27 US US19/003,281 patent/US20250275989A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| TW201808307A (zh) | 2018-03-16 |
| EP3493813A1 (en) | 2019-06-12 |
| RU2019101842A (ru) | 2020-09-04 |
| SG10201913574SA (en) | 2020-02-27 |
| TWI746610B (zh) | 2021-11-21 |
| AU2017305409C1 (en) | 2022-06-23 |
| JP7225088B2 (ja) | 2023-02-20 |
| JP2023058586A (ja) | 2023-04-25 |
| BR112019001948A2 (pt) | 2019-05-07 |
| MX2022011203A (es) | 2022-09-19 |
| AU2017305409A1 (en) | 2019-03-21 |
| SG11201900379RA (en) | 2019-02-27 |
| AU2024205530A1 (en) | 2024-08-22 |
| PH12019500242A1 (en) | 2019-07-29 |
| AU2022203977A1 (en) | 2022-06-30 |
| CN109789153A (zh) | 2019-05-21 |
| CA3031790A1 (en) | 2018-02-08 |
| MY197146A (en) | 2023-05-26 |
| AU2017305409B2 (en) | 2022-03-17 |
| TW202206081A (zh) | 2022-02-16 |
| MX395671B (es) | 2025-03-25 |
| US20250275989A1 (en) | 2025-09-04 |
| US20190125767A1 (en) | 2019-05-02 |
| RU2019101842A3 (es) | 2020-09-04 |
| JP2025041903A (ja) | 2025-03-26 |
| RU2760186C2 (ru) | 2021-11-22 |
| US10111890B2 (en) | 2018-10-30 |
| US20180055859A1 (en) | 2018-03-01 |
| WO2018026987A1 (en) | 2018-02-08 |
| EP3493813A4 (en) | 2020-04-08 |
| JP2019524767A (ja) | 2019-09-05 |
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