MX2019001103A - Sistema de suministro transdermico de donepezilo. - Google Patents
Sistema de suministro transdermico de donepezilo.Info
- Publication number
- MX2019001103A MX2019001103A MX2019001103A MX2019001103A MX2019001103A MX 2019001103 A MX2019001103 A MX 2019001103A MX 2019001103 A MX2019001103 A MX 2019001103A MX 2019001103 A MX2019001103 A MX 2019001103A MX 2019001103 A MX2019001103 A MX 2019001103A
- Authority
- MX
- Mexico
- Prior art keywords
- transdermal delivery
- donepezil
- delivery system
- therapeutic agent
- donepezil transdermal
- Prior art date
Links
- ADEBPBSSDYVVLD-UHFFFAOYSA-N donepezil Chemical compound O=C1C=2C=C(OC)C(OC)=CC=2CC1CC(CC1)CCN1CC1=CC=CC=C1 ADEBPBSSDYVVLD-UHFFFAOYSA-N 0.000 title abstract 7
- 229960003530 donepezil Drugs 0.000 title abstract 4
- 230000037317 transdermal delivery Effects 0.000 title abstract 3
- 239000003814 drug Substances 0.000 abstract 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 2
- 229940124597 therapeutic agent Drugs 0.000 abstract 2
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- 159000000011 group IA salts Chemical class 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 238000012385 systemic delivery Methods 0.000 abstract 1
Classifications
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- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
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- A61K31/19—Carboxylic acids, e.g. valproic acid
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- Health & Medical Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Polymers & Plastics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se describe un sistema de suministro transdérmico para el suministro sistémico de donepezilo, donde el sistema comprende una capa de depósito de fármaco comprendida de un copolímero de acrilato, glicerina, y base de donepezilo generada in situ mediante la reacción de donepezilo HCl y una sal alcalina. El sistema se proporciona para el tratamiento de enfermedad de Alzheimer y logra el suministro transdérmico del agente terapéutico que es equivalente a la administración del agente terapéutico oralmente.
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662367502P | 2016-07-27 | 2016-07-27 | |
| US201662367542P | 2016-07-27 | 2016-07-27 | |
| US201662423133P | 2016-11-16 | 2016-11-16 | |
| US201762444763P | 2017-01-10 | 2017-01-10 | |
| US201762444745P | 2017-01-10 | 2017-01-10 | |
| US201762457794P | 2017-02-10 | 2017-02-10 | |
| US201762504408P | 2017-05-10 | 2017-05-10 | |
| US201762504391P | 2017-05-10 | 2017-05-10 | |
| PCT/US2017/044050 WO2018022817A1 (en) | 2016-07-27 | 2017-07-26 | Donepezil transdermal delivery system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2019001103A true MX2019001103A (es) | 2019-09-27 |
| MX394249B MX394249B (es) | 2025-03-24 |
Family
ID=59523314
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019001103A MX394249B (es) | 2016-07-27 | 2017-07-26 | Sistema de suministro transdermico de donepezilo. |
| MX2022006681A MX2022006681A (es) | 2016-07-27 | 2019-01-25 | Sistema de suministro transdermico de donepezilo. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022006681A MX2022006681A (es) | 2016-07-27 | 2019-01-25 | Sistema de suministro transdermico de donepezilo. |
Country Status (10)
| Country | Link |
|---|---|
| US (13) | US9993466B2 (es) |
| EP (3) | EP3490558A1 (es) |
| JP (6) | JP7071330B2 (es) |
| KR (9) | KR20230109782A (es) |
| CN (5) | CN116270551A (es) |
| AU (7) | AU2017301928B2 (es) |
| CA (2) | CA3031945C (es) |
| MX (2) | MX394249B (es) |
| SG (1) | SG11201900692WA (es) |
| WO (3) | WO2018022816A1 (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016105499A1 (en) | 2014-12-23 | 2016-06-30 | Intellectual Property Associates, Llc | Methods and formulations for transdermal administration |
| EP3376852B1 (en) * | 2015-11-18 | 2025-06-04 | Commonwealth Scientific and Industrial Research Organisation | Rice grain with thickened aleurone |
| US10835499B2 (en) | 2015-12-30 | 2020-11-17 | Corium, Inc. | Systems and methods for long term transdermal administration |
| US11541018B2 (en) | 2016-06-23 | 2023-01-03 | Corium, Llc | Adhesive matrix with hydrophilic and hydrophobic domains and a therapeutic agent |
| CA3032103A1 (en) | 2016-07-27 | 2018-02-01 | Corium International, Inc. | Memantine transdermal delivery systems |
| KR20230109782A (ko) | 2016-07-27 | 2023-07-20 | 코리움, 엘엘씨 | 아민 약물의 나트륨 바이카보네이트 제자리 전환 구동된경피성 전달 |
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